Domestic Databases Research Articles

A Review of Clinical Research on Gamchosasim-tang for Helicobacter Pylori Associated Gastric Ulcer

Objectives: The purpose of this study was to investigate clinical research trends regarding the efficacy of Gamchosasim-tang on Helicobacter pylori-associated gastric ulcer.Methods: Studies were searched on Pubmed, CNKI, and domestic databases (OASIS, ScienceON, RISS, KISS, and Kmbase) using keywords such as “helicobacter”, “h. pylori”, “ulcer”, and “Gancao Xiexin.” Data on the publication year, characteristics of patients, diagnosis methods, interventions, outcome measures, and results were extracted. The quality of each study was assessed using a risk-of-bias tool.Results: In total, eight studies were selected. All were randomized-controlled trials. Gamchosasim-tang and quadruple therapy were co-administered for the treatment group in most of the studies. A combination of Gamchosasim-tang and eradication therapy was effective in improving disease-associated symptoms and lowering recurrence rate. No obvious side effects were observed in any of the studies.Conclusion: Gamchosasim-tang can be a safe and effective treatment method for helicobacter pylori-associated gastric ulcer, so it can be used in clinical practice.

Research Trends of CV23 Electroacupuncture: A Literature Review Focusing on PubMed and Domestic Studies

Objectives: The purpose of this study was to analyze the research trends of electroacupuncture (EA) at CV23.Methods: Studies published until July 2024 were searched on PubMed and domestic databases (OASIS, ScienceON, RISS, KISS, KCI, KMbase, and DBpia) using the keywords “CV23”, “lianquan”, “electroacupuncture”, “염천”, “전침”, and “전기자극”.Results: A total of 16 studies were selected. There were 6 randomized controlled trials, 1 case report, and 9 experimental studies. Of the 16 papers selected, 15 examined the effect of EA at CV23 on improving swallowing function. Clinical studies found that EA at CV23 was effective in improving dysphagia, aphasia, and drooling symptoms through mechanisms such as increased hyolaryngeal movement, normalization of pathologically elevated NO, ET, and improvement of excitement of the swallowing motor cortex. According to experimental studies, EA at CV23 activates the brain region associated with swallowing function, promotes the swallowing reflex by increasing neurotransmitters, improves electromyography of the swallowing muscles, and improves blood flow around CV23.Conclusion: Electroacupuncture at CV23 may be an effective and safe method for post-stroke dysphagia, post-stroke aphasia, and post-stroke drooling. In the future, research should be conducted in different diseases and high-quality studies should be conducted.

An Integrative Review of Psychosocial Intervention Programs for Children and Adolescents who Experienced Traumatic Events

Background: This integrative review study aims to analyze the core components, intervention strategies, and effects of psychosocial intervention programs conducted for children and adolescents in Korea who have experienced traumatic events.Methods: The integrative review involved a search of major domestic databases using key terms such as 'children’, 'adolescents’, 'trauma’, 'post-traumatic stress’, 'intervention’, and 'education’. A total of 10 studies were selected for analysis based on predefined criteria.Results: The 10 selected studies were categorized into three types of interventions based on the environment and structure of the intervention delivery: individual-based interventions targeting only children and adolescents, family-based interventions involving family members, and school-based interventions conducted within schools. These interventions were found to be effective in addressing mental health issues caused by trauma in children and adolescents.Conclusions: Despite the serious nature of traumatic experiences among children and adolescents, this integrative review found that domestic research on psychosocial interventions for this population lacks rigorous study design and is limited in the selection of participants and trauma events. Therefore, the study suggests the need for the development and dissemination of more proactive psychosocial interventions for children and adolescents. The findings of this study are expected to serve as foundational data for the development of trauma managing programs for this population.

The Prevalence of Brucella Spp. in Dairy Products in Iran: A Systematic Review and Meta-Analysis.

Brucellosis, a significant zoonotic disease, threatens food safety substantially, particularly in developing nations such as the Middle East. This study aimed to comprehensively assess the prevalence of Brucella spp. in Iranian milk and dairy products through a systematic review and meta-analysis. A thorough search of international and domestic databases from January 2008 to October 2023 identified 38 relevant studies encompassing 11,130 samples for meta-analysis. The overall prevalence of Brucella spp. in Iranian dairy products was 22% (95% CI: 16-28%). The highest and lowest overall prevalence of Brucella spp. in milk were found in raw goat milk 27% (95% CI: 11-42%) and raw camel milk 15% (95% CI: -0.42 to 72%), respectively. The overall prevalence of traditional cheese, ice cream, and cream is estimated to be 9% (95% CI: -16 to 35%), 2% (95% CI: -2.78 to 2.82%), and 9% (95% CI: -0.94 to 1.12%). Geographical disparities were evident, with Zanjan province reporting the highest contamination rate, 53%, while Razavi Khorasan province had the lowest, 1%. However, the prevalence of Brucella spp. in Iranian dairy products has fluctuated over time, with a significant association between the study year and sample size. Comprehensive planning, robust policy implementation, and rigorous monitoring are imperative to mitigate and ultimately eliminate Brucella contamination in dairy products effectively. Further research is essential to refine prevalence estimates and develop targeted prevention strategies to safeguard public health.

Current status and prospects of health hazards database for chemical hazards

In order to facilitate technical personnel related to occupational health and safety production to search, obtain, and master information on the hazard classification and health effects of chemical hazards, this article surveyed 14 commonly used foreign databases and 9 commonly used domestic databases, analyzed the characteristics, main content, scope of application, and network resources of each database, and considered the development of database for occupational health hazard of chemical hazards.

Spirituality, a Neglected Dimension in Improving the Lifestyle of Coronary Artery Patients by Nurses: A Scoping Review.

By modifying the lifestyle of patients, the risk factors of Coronary Artery Diseases (CADs) are adjusted. This study was performed with the aim to investigate the role of nurses in the lifestyle of coronary artery patients. This scoping review was conducted with the question of the role of nurses in improving the lifestyle of coronary artery patients. This study was conducted in databases and search engines of ScienceDirect, Springer, Scopus, PubMed, MEDLINE, and Google Scholar for English texts, and in the Magiran and Scientific Information Database (SID) databases and search engines for the texts printed in Persian. The search for articles printed from 2012 to 2022 was conducted based on the keywords used in the title and abstract of the articles. The keywords used to search domestic databases included nursing, lifestyle and healthy lifestyle, and heart diseases (based on MeSH). Nurses have made significant efforts and performed interventions to improve the lifestyle of coronary artery patients through guidance and education regarding the improvement of their diet and mobility, compliance with their treatment regimen, and reduction of the risk factors of CAD. In the psychological dimension, they had a positive effect in some fields such as stress management and mental health. However, in the spiritual dimension, effective studies and interventions have not been conducted by nurses. The role of nurses in the lifestyle of coronary artery patients is effective in the physical dimension, limited in the psychological dimension, and neglected in the spiritual dimension.

A Review of Domestic Research on Traditional Korean Medicine for Chemotherapy-Induced Peripheral Neuropathy

Objectives: This study was performed to research Korean medical treatment methods for chemotherapy-induced peripheral neuropathy by summarizing domestic studies.Methods: All domestic research papers on the Korean medical treatment of chemotherapy-induced peripheral neuropathy were selected from the literature published until April 2024 in four domestic databases. In total, 26 domestic papers were selected.Results: Eighteen clinical studies and eight experimental studies were published by April 2024. Most of the studied patients were in their fifties, and 93.4% of the subjects were women. Uchashinki-hwan (牛車腎氣丸) was the most frequently prescribed herbal formula, and Rehmanniae Radix Preparata was the most commonly used herb. All studies showed significant effects of Korean medical treatment, and any adverse events were not reported.Conclusion: This study included all domestic research papers on chemotherapy-induced peripheral neuropathy to identify research trends in the Korean medicine community. Based on this, it is meaningful to confirm areas that need to be supplemented in future research plans. However, large-scale studies are needed.

Meta-Ethnography, a Method for the Synthesis of Qualitative Research: A Narrative Review

Background: Synthesis studies are used for the retrieval, review, synthesis, analysis, and integration of the findings of original studies. The purpose of this review was to shed more light on how meta-ethnography works as a method of inductive and interpretative knowledge synthesis, and on its application and implementation in medical sciences. Methods: This was a narrative review study and the statistical population included all scholarly publications on the synthesis of qualitative studies and meta-ethnography published from 1998 to 2022. The search in international and domestic databases led to the extraction of 118 books and articles. After reviewing the titles, abstracts, and full texts of these publications, we included 2 books and 8 articles in the review. Results: Meta-ethnography is used for synthesizing the knowledge obtained from qualitative studies to re-conceptualize their findings. There are seven phases in the process of meta-ethnography: Getting started; Deciding on what is of initial interest; Reading the studies; Determining how the studies are related; Translating the studies to each other; Synthesizing the translations; and expressing the synthesis. The number of studies required to perform meta-ethnography has been recently suggested to be 40. Strategies for updating meta-ethnography include repeating the previous strategy and reformulating the strategy according to a new objective, a revised review question, or new inclusion criteria. Conclusion: Noblit and Hare introduced meta-ethnography in 1988 as a qualitative research method for the synthesis of educational ethnographies. Today, it is widely used in healthcare research.

Modern pharmacotherapy for cholestasis syndrome

Diseases of the hepatobiliary system today remain an urgent health problem worldwide. A significant percentage of gastroenterological patients are people suffering from cholestasis syndrome. In gastroenterology, there are a number of nosological forms accompanied by the development of cholestasis syndrome. This pathological condition has many etiological factors, but in general, the mechanisms of its formation for various reasons are largely similar. When working with this group of patients, it is necessary to take into account the peculiarities of the clinical picture, which may vary depending on the etiology of the cholestatic syndrome. The fact of the economic burden in this pathology is also important, because sometimes it is necessary to resort to high-tech examination methods and expensive laboratory screening to perform high-quality differential diagnosis. As for the treatment of cholestatic syndrome, at the moment there are many drugs with different mechanisms of action, the predominant part of which, according to randomized clinical trials and meta-analyses, has proven effectiveness. In this article, based on literature sources taken from foreign and domestic databases, the etiology and pathogenesis of the development of cholestasis syndrome, the clinical picture and approaches to the diagnosis of this condition are considered. When considering the treatment of cholestatic syndrome, this article focuses on therapy with ursodeoxycholic acid drugs, in particular Ecurochol. A clinical case is also considered on the example of a patient with cholestasis syndrome who was prescribed treatment with Ecurochol and who showed positive dynamics due to improvements in the ultrasound picture of the abdominal organs.

Analysis of research trends on microneedle patches loaded pharmacopuncture preparation: A Literature Review

Objectives: The purpose of this study is to review the dissolving microneedle patches literature, which is loaded with pharmacopuncture preparation. By exploring types of pharmacopuncture preparation applied to microneedle patches, we aim to develop new potential preparation.Methods: This review included both animal and human studies that published between February 2015 and March 2024. After searching, no RCTs were found, the final selected in-vivo and in-vitro studies were analyzed. A total of 13 articles were retrieved from the international database, and a total of 5 articles were retrieved from the domestic database. Finally, 7 studies were selected, and evaluated by the published year, country of publication, types of animal model, disease type, retention type, evaluation index, adverse effects.Conclusions: According to 7 studies, pharmacopuncture preparation coated dissolving microneedle patch include bee venom, placenta, and ginseng in osteoarthritis, rheumatoid arthritis, hypertrophic scar, psoriasis, and neurodegeneration. In the future, follow-up studies on the safety, retention time, and optimal effective dose of the microneedle patches are expected.

Robot-Assisted Gait Training in Individuals With Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Spinal cord injury (SCI) rehabilitation emphasizes locomotion. Robotic-assisted gait training (RAGT) is widely used in clinical settings because of its benefits; however, its efficacy remains controversial. We conducted a systematic review and meta-analysis to investigate the efficacy of RAGT in patients with SCI. We searched international and domestic databases for articles published until April 18, 2024. The meta-analysis employed a random effects model to determine the effect size as either mean difference (MD) or standardized MD (SMD). Evidence quality was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Twenty-three studies with a total of 690 participants were included in the final analysis. The overall pooled effect size for improvement in activities of daily living was 0.24, with SMD (95% confidence interval [95% CI], 0.04-0.43; GRADE: high) favoring RAGT over conventional rehabilitation. Muscular strength (MD, 0.23; 95% CI, 0.02-0.44; GRADE: high), walking index for SCI (MD, 0.31; 95% CI, 0.07-0.55; GRADE: moderate) and 6 min walk test distance (MD, 0.38; 95% CI, 0.14-0.63; GRADE: moderate) showed significant improvement in the robot group. Subgroup analysis revealed that subacute patients and intervention periods >2 months were more effective. This meta-analysis revealed that RAGT significantly improved activities of daily living, muscular strength, and walking abilities. Additional studies are needed to identify the optimal treatment protocol and specific patient groups for which the protocol is most effective.

Biomarkers of oxidative stress and proteopathies in the diagnosis of neurodegenerative diseases

Introduction. Despite numerous studies in the field of neurodegenerative diseases, the exact mechanisms of these processes have not yet been identified. The purpose of this review is to analyze the methodological approaches necessary to revise the traditional and create new reliable prognostic and diagnostic algorithms that reflect pathogenetic features at different stages of neurodegeneration and atypical course of the disease. Material and methods. The review highlights the results of clinical and experimental studies obtained using a complex of clinical, laboratory and instrumental methods with an emphasis on markers of oxidative stress and proteopathy. In preparing the materials, sources from international and domestic databases were used: Scopus, Web of Science, Pub Medline, RSCI mainly for the last 15 years. Results. An idea has been formed about the molecular mechanisms of neural tissue regression in a number of neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s disease. The relationship between the parameters of the oxidative process and the features of metal-energy shifts in organs and organ systems is demonstrated. The role of markers of oxidative stress in the early stages, when the process of inflammation prevails and in the atypical course of the disease, is shown. Valuable biochemical markers are cytokines, glutathione levels, myeloperoxidase activation, and isoprostanes. The review points to the prospect of including in screening indicators of iron and other metals such as Zn, Mg, affecting the clinic accumulation of β-amyloid, in connection with which they can be considered as the basis for the progression of neurodegeneration. New data on the contribution of halogenating stress to the pathogenesis of neuroinflammation are presented. An aspect requiring development in the field of biomarkers for assessing the duration of the disease and prognostic prospects is the data on the correlation of metabolic shifts in the intestinal microbiota with the duration of the disease and the inflammatory process. Essential for the creation of express diagnostic methods is the determination of redox balance as an integral marker in saliva, which has obvious advantages over the use of biological fluids, such as liquor and serum. Conclusion. The prospects of creating new prognostic and diagnostic schemes are associated with complexes, including laboratory and instrumental methods, in blood, liquor and saliva. Evaluation of the sensitivity and specificity of new markers depending on the clinical diagnosis allows the selection of pathogenetically significant markers in the early stages of the disease, with atypical neurodegeneration, to establish subtypes of the disease, to carry out their differential diagnosis.

Влияние загрязнения атмосферы на респираторное здоровье детей

The review is devoted to a highly relevant problem – the impact of polluted air on the respiratory health of the child population. The main pollutants (pollutants) of the air in both urban and rural areas, the depth of their penetration into the respiratory tract are analyzed in detail; evidence is given of an increased risk of respiratory infections and exacerbations of bronchial asthma in children living in large cities. The following issues were discussed: controlled exposure of pollutants and respiratory tract infections; mechanisms of negative effects of polluted air on lungs; is reducing air pollution able to improve human health? It should be noted separately that, despite a thorough search in all foreign and domestic databases available to authors, in the 21st century, single articles are devoted to air pollution issues. This can serve as an indicator of the importance and necessity of conducting in-depth research on this issue. Key words: air pollution, particulate matter, children, respiratory infections, asthma

Analysis of conditions and nature of work of therapists: A literature review

Introduction: Currently, insufficient attention is paid to nonspecific negative factors of the working environment of therapists, such as exposure to electromagnetic fields from electronic devices, lack of standards for the area of working premises (residence rooms), and non-compliance with the optimal work/rest schedule. Objective: Based on the analysis of literature data, to identify contemporary nonspecific risk factors at workplaces of general practitioners and outline the main ways of their prevention. Materials and methods: We have reviewed scientific publications indexed in international (Web of Science, Scopus, PubMed) and domestic (RSCI) databases for 2014–2023. Of more than 2,000 sources found, we selected 89 given the keywords and then included 49 papers published over the past 5 years in the review. Results: Modern therapists are exposed to combined physical and biological factors and experience psychological stress, leading to a higher incidence of work-related diseases. Long-term exposures to risk factors of the work environment increase the risk of job burnout and psychological maladjustment resulting in negative personality changes, deterioration of health and relationships with colleagues, patients, relatives and, ultimately, a decrease in the effectiveness and quality of medical care provided. Conclusions: We have considered and systematized factors of the work environment of therapists with a focus on less studied, but no less significant current nonspecific negative factors, and outlined the main directions for solving the problem of maintaining health of medical professionals.

Analysis of factors and trends in the DBMS market in Russia

At the present stage of development of information systems, there is a growing need for reliable systems for storing and retrieving information. Each organization uses a significant amount of data in its activities, which makes it necessary to have a reliable DBMS, which will allow organizing the storage of a large amount of information with high speed of search and update. Due to the current political situation in Russia, there is a tendency towards import substitution of software, including DBMS. This situation became the main impetus for the development of domestic software. The development of domestic database management systems is also encouraged by government policy. All this led to an increase of popularity and number of developments of domestic software in general and DBMS in particular.

An Integrative Review of Psychosocial Intervention Programs for Infertile Females

Background: This study aims to analyze intervention studies conducted on infertile females in South Korea and research and research the core elements comprising these studies.Methods: The integrative review was conducted based on the guidelines of Whittmore and Knafl, and included the following steps: problem identification, literature search, data evaluation, data analysis, and presentation. Next, six domestic databases were searched using keywords such as ‘infertility’, ‘intervention’, and ‘education’ in Korean and English, and published studies were reviewed according to specific criteria and quality assessment.Results: Among 4,109 searched papers, 6 were selected for the final data analysis. A total of six interventions were conducted in the selected articles, and each strategy was variously categorized into cognitive, emotional, behavioral, relational, and physical aspects. All interventions were found to be effective in promoting psychosocial health in infertile females.Conclusions: Despite the fact that female infertility is a major public health problem in Korea, the low number of articles reveals a relative lack of psychosocial intervention studies. Therefore, it is suggested that future studies incorporate physiological endpoints into psychosocial studies, and we hope that this study will serve as a basis for developing programs for infertile females in the future.

Developing Cluster-based Fire Following Earthquake Risk Evaluation Method using Building Registration Data

The Pohang earthquake raised concerns about the potential occurrence of fire-following earthquake (FFE). The United States and Japan effectively manage FFE risks through ignition and fire-burned ratio assessments. This study introduced a streamlined method for assessing FFE risk by leveraging a public building database (e.g., building registration data). The proposed method was applied to the Pohang regions. Hence, the ignition and fire spread calculation methods employed in the United States and Japan were adapted to suit the domestic database. The method was then implemented in clusters identified in the Pohang region. The fire-burned ratios, accompanied by the covering volume fraction (CVF) for each cluster, were computed using the extracted and newly developed building information. This method was used to evaluate the FFE risks in the Pohang areas.

PROBLEMS OF IMPLEMENTING BUILDING INFORMATION MODELING (BIM) TECHNOLOGY IN CONSTRUCTION

The article explores issues related to design problems and the possibility of using building information modeling (BIM) to solve them. The article begins with the definition of information modeling technology and the scope of its application, the relevance of the topic at the legislative level is indicated. The characteristic features of the modeling levels from 3D to 6D are highlighted and described, conclusions are drawn on their use and solving problems related to BIM. The topic of belonging of the modeling level to a certain stage of design is revealed, special attention is paid to the estimate case. The application of information modeling in the construction industry of Russia is considered. Barriers to the introduction of TIM technologies in the construction industry are highlighted and described, major Russian companies that have already implemented this system in their work are highlighted. Special attention is paid to the lack of domestic databases, software, trained personnel and examples are given to address these issues. The topic of families, the scope of their application, the pros and cons of this modeling method are revealed. There is a plus of working with TIM for designers of private houses, the ease of reading drawings for builders. The possibility of automating the design, construction and operation of the building is noted.

A Review of Domestic Research on Traditional Korean Medicine for Chronic Prostatitis in Clinical Research Papers

Objectives: This study was conducted to examine the current status of traditional Korean medicine studies on chronic prostatitis in Korea, identify deficiencies, and suggest future medicine research methods to lay the foundation for traditional Korean medicine treatment.Methods: All domestic clinical research papers on the traditional Korean treatment of chronic prostatitis were selected from the literature published until October 2023 in three domestic databases. A total of 13 selected research data were classified into clinical research papers.Results: In clinical research papers, the basis for the diagnosis of cases was clinical symptoms through medical history listening and diagnosis through past visits to hospitals. The average treatment period was 7 weeks, and the duration of treatment was not significantly affected by the duration of the disease. The most widely used Korean medicine treatment intervention was herbal medicine.Conclusions: This study included all domestic clinical research papers on chronic prostatitis to identify research trends in the Korean oriental medicine community. Based on this, it is meaningful to confirm areas that need to be supplemented in future research plans.

Metaverse in the development of “smart cities”: Problems of data management

Aim. To identify the main problems of handling digital data in metaverses of “smart cities”, as well as to develop recommendations for their solution.Objectives. To analyze the scientific sources that investigate the issues of applying the metaverse technology for the development of “smart cities”; to identify the problems of data management in the development of metaverse “smart cities”; to offer recommendations on data management in the implementation of this technology.Methods. The object of the study is the modern concept of digital metaverse as a new stage of transformation of socio-economic systems in the conditions of rapid development of digital technologies. The subject of the study is the problematics of handling digital data in the framework of the realization of the ideas of digital metaverse “smart cities”. The research algorithm consisted of three stages: analysis of publications on the subject of the study in foreign and domestic databases of scientific literature, identification of problems of data handling in digital systems and virtual environments, development of recommendations for leveling the identified problems.Results. The study shows that the most important resource for the development of metaverse “smart cities” is digital data; it is argued that the main condition for the development of metaverse “smart city” is the formation of a common space of data exchange of the main participants within the metaverse “smart city”. The main problems related to the use of digital data in the development of smart city metaverse are summarized. The novelty of the study lies in the development of recommendations for the formation of a system of handling digital data in the development of “smart cities” metaverse.Conclusions. The obtained results contribute to the development of scientific direction related to the digitalization of urban spaces within the concept of “smart city” metaverse, and future studies devoted to this topic.