Dodecylethyldimethylammonium Bromide Research Articles

Stimuli Responsive Molecular Exchange of Structure Directing Agents on Gold Nanobipyramids: Cancer Cell Detection and Synergistic Therapeutics.

Surface-engineered gold nanoparticles have been considered as versatile systems for theranostics applications. Moreover, surface covering or stabilizing agents on gold nanoparticles especially gold nanobipyramids (AuNBPs) provides an extra space for cargo molecules entrapment. However, it is not well studied yet and also the preparation of AuNBPs still remains dependent largely on cetyltrimethylammonium bromide (CTAB), a cytotoxic surfactant. Therefore, the direct use of CTAB stabilized nanoparticles is not recommended for cancer theranostics applications. Herein, we address an approach of dodecyl ethyl dimethylammonium bromide (DMAB) as biocompatible structure directing agent for AuNBPs, which also accommodate anticancer drug doxorubicin (45%), an additional chemotherapeutics agent. Upon near-infrared light (NIR, 808 nm) exposure, engineered AuNBPs exhibit (i) better phototransduction (51 °C) due to NIR absorption ability (650-900 nm), (ii) photo triggered drug release (more than 80%), and (iii) synergistic chemophototherapy for breast cancer cells. Drug release response has been evaluated in tumor microenvironment conditions (84% in acidic pH and 80% at high GSH) due to protonation and high affinity of thiol binding with AuNBPs followed by DMAB replacement. Intracellular glutathione (GSH, 5-7.5 mM) replaces DMAB from AuNBPs, which cause easy aggregation of nanoparticles as corroborated by colorimetric shifts, suggesting their utilization as a molecular sensing probe of early stage cancer biomarkers. Our optimized recipe yield is monodisperse DMAB-AuNBPs with ∼90% purity even at large scales (500 mL volume per batch). DMAB-AuNBPs show better cell viability (more than 90%) across all concentrations (5-500 ug/mL) when directly compared to CTAB-AuNBPs (less than 10%). Our findings show the potential of DMAB-AuNBPs for early stage cancer detection and theranostics applications.

Evaluation of surfactants as solubilizing medium for levofloxacin

Micelles are well established solubilizing agents which can solubilize poorly soluble drug moieties. For choosing the optimum solubilizing medium for levofloxacin (LEVO) solubilization, studies were carried out using various surfactants viz., tyloxapol, tween 80, tween 20, sodium cholate, (NaC), sodium dodecyl sulphate (SDS), dodecyl ethyl dimethyl ammonium bromide (DDAB), dodecyl trimethyl ammonium bromide (DTAB), cetyl trimethyl ammonium bromide (CTAB). UV–Visible and fluorescence spectroscopy studies were used to evaluate the binding constants (Kb) and quenching constants (Ksv) which were found to be highest for CTAB based systems. Variation in thermodynamic parameters viz., free energy (∆G0m), enthalpy (∆H0m) and entropy (∆S0m) of drug-surfactant associations were estimated via conductivity measurements. Changes in enthalpy and entropy for LEVO-CTAB systems suggested increase in partitioning of drug in CTAB micelles. Solubility of LEVO showed a linear increase with increasing CTAB concentrations. Interactions of LEVO with serum protein (bovine serum albumin; BSA) were investigated in presence of surfactants using UV–Visible and fluorescence studies. Long term biocompatibility of LEVO-CTAB formulation was observed in association with structural (collagen) and transport proteins (BSA, human serum albumin; HSA) via circular dichroism studies.

Electrochemical exfoliation of graphite in nanofibrillated kenaf cellulose (NFC)/surfactant mixture for the development of conductive paper

The effect of incorporating common dodecyl anionic and cationic surfactants such as dodecyltrimethylammonium bromide (DTAB), dodecylethyldimethylammonium bromide (DDAB), and sodium dodecylsulfate (SDS) in nanocomposites of reduced graphene oxide and nanocellulose are described. The stabilization and electrical properties of the nanocomoposites of reduced graphene oxide (RGO) and nanofibrillated kenaf cellulose (NFC) were characterized using four-point probe electrical conductivity measurements. Raman spectroscopy, field emission scanning electron microscopy, and high-resolution transmission electron microscopy were used to investigate dispersion morphology and the quality of RGO inside the NFC matrices. Small-angle neutron scattering (SANS) was used to study the aggregation behavior of the aqueous surfactant systems and RGO dispersions. The cationic surfactant DTAB proved to be the best choice for stabilization of RGO in NFC, giving enhanced electrical conductivity five orders of magnitude higher than the neat NFC. The results highlight the effects of hydrophilic surfactant moieties on the structure, stability and properties of RGO/NFC composites.

Self-Assembly and Thermodynamic Properties of Dodecyldimethylethylammonium Bromide in Ethylene Glycol or Ethylene Glycol Oligomers and Water Mixed Solutions

The self-assembly behavior of dodecyldimethylethylammonium bromide (DEDAB) in mixed solvent media of ethylene glycol (EG)/water, polyethylene glycol 200 (PEG 200)/water, or polyethylene glycol 400 ...

Mixed surfactant (altering chain length and head group) aggregates as an effective carrier for tuberculosis drug

Surface properties and aggregation behavior of cationic-cationic and cationic-non-ionic mixed surfactant systems viz. Dodecylethyldimethylammonium bromide (DDAB) with a series of double chain cationic surfactants (DiDDAB, DMDTAB, and DODAB) and non-ionic surfactants (Brij 96, Tyloxapol and Tween 80) were analysed using surface tension and transmission electron microscopy (TEM). The effect of chain length of cationic surfactant and hydrophilic-lypophilic balance (HLB) prominently observed in critical aggregation (cac) value. The aqueous solubility of anti-tuberculosis drug: rifampicin (RIF) was comparatively studied by UV–vis spectroscopy in presence of formulated micelles and vesicles. RIF was significantly solubilised in aqueous medium using all the formulated aggregates. RIF is very unstable in basic medium (above pH-7) and in oxidizing media. Therefore, stability at pH-13 as well as in strong oxidising environment was monitored using UV–vis spectroscopy. To trace the locus of the drug encapsulation in the micelles/vesicles, fluorescence spectroscopy and TEM studies were carried out. Both the techniques stemmed in complimentary results and confirmed that, RIF is majorly populated at polar medium in cationic-cationic vesicles and favour to reside at hydrophobic medium of the nonionic-cationic micelles.

Synthesis of less toxic gold nanorods by using dodecylethyldimethylammonium bromide as an alternative growth-directing surfactant

Gold nanoparticles having a rod-like morphology are regularly investigated as potential nano-therapeutic materials owing to their interesting optical properties, facile surface modification, tunable aspect ratios, and low cytotoxicity. Gold nanorods are historically prepared starting from HAuCl4 in the presence of ascorbic acid, silver nitrate, and the growth directing surfactant, cetyltrimethylammonium bromide (CTAB). While CTAB drives a rod-like morphology, it is known to be cytotoxic. This inherent toxicity is often addressed by removing or masking the native CTAB surfactant present on the nanorod surface. In the current study we have investigated a less toxic alternative surfactant, dodecylethyldimethylammonium bromide (C12EDMAB), as a possible growth-directing agent. Monodisperse gold nanorods having various lengths have been grown in the presence of C12EDMAB. SEM data suggests that the quantity of C12EDMAB on the rod’s surface is much higher than that of CTAB. Toxicity assays were performed on HEp-2 and A549 cells showing lower toxicity at select concentrations for C12EDMAB coated rods.

Dodecyl ethyl dimethyl ammonium bromide capped WO3nanoparticles: efficient scaffolds for chemical sensing and environmental remediation

The current work revealed the comparative analysis of bare and surface functionalized tungsten trioxide (WO3) nanoparticles that can be successfully utilized as competent photocatalysts for the degradation of organic dyes and as efficient electron transporters for the fabrication of highly sensitive electrochemical sensors in aqueous medium. The room temperature synthesis of WO3 nanoparticles with good crystallinity was carried out in the presence of dodecylethyldimethyl ammonium bromide (DEDMAB) as the template by a wet chemical process. The surface functionalized nanoparticles possess a controllable band gap and act as an effectual substrate for electrochemical sensing of hydrazine. The sensitivity values of the fabricated sensor range from 9.39 μA μM(-1) cm(-2) with the limits of detection ranging from 28.8 μM. Furthermore, surface modulated particles also exhibited enhanced photocatalytic performance in the photodegradation of Congo red dye with an efficiency of 98.67% compared to bare WO3 nanoparticles without any modification. The comparison of the current responses and photodegradation activity of the bare and capped WO3 particles illustrates an excellent sensitivity, selectivity and operational stability of the as-functionalized nanoparticles.

Micellization and Surface Properties of Alkanediyl-1,4-bis(tetradecyldimethylammonium Bromide) Gemini Surfactants with Dodecylethyldimethylammonium Bromide

Mixed micellization and surface properties of three cationic gemini surfactants, viz., (butanediyl-), (pentanediyl-), (hexanediyl-)-1,4-bis(tetradecyldimethylammonium bromide) (14-s-14; s = 4–6) with dodecylethyldimethylammonium bromide have been studied by conductometric, tensiometric, and fluorimetric techniques at 298 K. Values of cmc, ideal cmc(cmc*), degree of counter ion dissociation (g), micellar mole fractions of the components, and interaction parameters have been determined. Further, activity coefficients of the components, surface excess concentration (Γmax), minimum surface area per molecule (Amin), surface pressure at the cmc (πcmc), average aggregation numbers of the micelles (Nagg), excess Gibbs free energy (), and Gibbs free energy of micellization () were also calculated and discussed. The compositions of the mixed systems were varied between 0 and 1. It is observed that the values of cmc, g, , , and Γmax decreases whereas Amin increases with augmentation of 14-s-14 (s = 4–6) mole fraction in the mixed systems. The negative values of interaction parameters (βσ and βm) obtained for mixed micelle formation indicate attractive interaction between the components leading to nonideality. The nonideal behavior has been theoretically treated by Clint's and Rubingh's model in light of regular solution theory.

Aggregation behavior of Dioctadecyldimethylammonium chloride in mixed cationic surfactant system

The spontaneous formation of mixed vesicles, their coexistence and solubilization due to formation of mixed micelles were investigated for the double chain Dioctadecyldimethylammonium chloride (DODAC) and a single chain Dodecylethyldimethylammonium bromide (DDAB), mixed cationic surfactants. Various analytical techniques viz., conductivity, surface tension, fluorescence and absorption spectroscopy were utilized. To gain an insight into the mixed aggregate formed, thermodynamic free energy, molecular interaction parameter, the total critical micelle concentration and degree of ionization of the mixed micelle (α) as a function of molar ratio were assessed. Acoustic properties of the mixed surfactant system as functions of temperature were also calculated. Interaction of pyrene with mixed aggregates in the present system was assessed through fluorescence spectroscopy (at cvc as well as cmc) at 298.15K and atmospheric pressure.

Solubilization efficiency of mixed cationic aggregates towards aromatic compounds

The present work deals with the aggregation behaviour and structure transitions of mixed system of dioctadecyldimethylammonium chloride (DODAC) and dodecylethyldimethylammonium bromide (DDAB) in order to further evaluate its solubilization efficiency of aromatic compounds. Structure transitions and stability of the prepared formulations have been assessed by differential scanning calorimetric (DSC), zeta potential and fluorescence spectroscopy. The vesicle–micelle transition has been analyzed by fluorescence anisotropy measurement at various pH (3.2, 7.2 and 11.2). The mixed surfactant system has further been utilized to enhance the solubility of a hydrophobic moiety i.e. pyrene. Various parameters such as molar solubilization ratio (MSR), partition coefficient (Km), association constant (K1) and average number of pyrene molecule associated with aggregate (SM) have been estimated. Present work provides information about the precise vesicle–micelle transition point in a mixed micellar system and takes into account the solubilization selectivity, where vesicles show higher solubilization efficiency as compared to micelles.

Thermodynamic properties of new gluconamide-based cationic surfactants in aqueous solution: Experimental and modeling approaches

The micellization processes of 2-(alkyldimethylammonio)ethylgluconamide bromides (CnGAB), dodecyltrimethylammonium bromide (DTAB) and dodecylethyldimethylammonium bromide (DEDAB) were studied using solution conductivity and isothermal titration calorimetry (ITC). The critical micelle concentrations (CMC), the degree of counterion binding (β), the enthalpies (ΔHm) and entropies (ΔSm) of micellization as well as the contributions of the headgroups to Gibbs free energies (ΔGm0(hy)) were calculated. Approximate relative partial enthalpies (L2) were evaluated as functions of concentration from the calorimetric curves. In comparison with DTAB, the hydrophobicity of C12GAB is reduced by an extent corresponding to the shortening of DTAB’s alkyl chain by one methylene group. The micelles of C12GAB are hydrated by one methylene group deeper than those of DTAB. The free energy of the transfer of the headgroup from the bulk solution to the micelle is more favorable for DTAB than C12GAB. This effect is approximately equal to the ΔGm0(CH2) contribution. In contrast to the usual ionic surfactant behavior, the degree of counterions binding for CnGABs decreases with increasing alkyl chain length. This is supposed to be a consequence of screening of the charged layer of the micelle by the large, hydrated and hydrogen-bonded headgroups from the bromide anions in bulk solution. The computational modeling made it possible to relate the surfactants’ molecular properties to the interactions the surfactants enter into, suggesting that, due to the strongly polar character of their headgroup, CnGABs form small premicellar aggregates.

Micellization behavior of dodecylethyldimethylammonium bromide as a function of temperature and concentration

Micellization behavior of aqueous solutions of dodecylethyldimethylammonium bromide has been studied as a function of concentration and temperature employing densiometry, viscometry, ultrasound velocity measurements and conductometry. Density data has been used to evaluate apparent molar volumes and apparent molar expansion of surfactant monomers and micelles. Isoentropic compressibility, apparent molar isoentropic compressibility and apparent molar compression values and various acoustic interaction parameters like molar sound velocity, acoustic impedance and Wada's constant, have also been calculated using ultrasound velocity data. Conductivity measurements have been used to evaluate the degree of counterion binding. All methods yielded almost similar critical micellar concentration values. The data was used to discuss thermodynamics of micellization based on phase separation and mass action models. Micellization process of the surfactant was found to be spontaneous.

Thermal imidization peculiarities of electrospun BPDA-PDA/ODA copolyamic acid nanofibers

Copolyamic acid (coPAA) based on 4,4′-oxydianiline (ODA), p-phenylenediamine (PDA) and 3,3′,4,4′-biphenyltetracarboxylic dianhydride (BPDA) was synthesized in N,N-dimethylformamide (DMF). The preparation of continuous defect-free nanofibers from BPDA-PDA/ODA coPAA was achieved by electrospinning of its DMF solution. The average fiber diameter significantly increased from 385 to 590 nm on increasing the total polymer concentration of the spinning solutions from 5 to 7 wt%. The addition of dodecylethyldimethylammonium bromide (DEDAB) salt to the spinning solution resulted in the procurement of coPAA nanofibers with a much smaller (more than 3 times) average diameter. The coPAA imidization process was investigated through FTIR spectroscopy. The chemical composition and morphology of coPI nanofibers were assessed by X-ray photoelectron spectroscopy and scanning electron microscopy. Imidization under isothermal conditions proceeded faster in the first stage. Activation energies in the first and second imidization stages were similar when DEDAB had been added into the electrospinning solution. Cylindrical or crimped defect-free nanofibers of BPDA-PDA/ODA copolyimide (coPI) were obtained by the stepped thermal imidization of coPAA. The morphology of coPI nanofibers depends on the curing temperature. The crimped coPI nanofibers were most probably due to the relief of residual stress when the curing temperature was higher than the polymer glass transition temperature. Open image in new window

Activity and thermodynamic parameters of some surfactants adsorption at the water–air interface

Measurements of the surface tension of aqueous solutions of Triton X-100, Triton X-114, Triton X-165, sodium dodecylsulfate, sodium hexadecylsulfonate, cetyltrimethylammonium bromide, cetylpyridinium bromide, sodium N-lauryl sarcosinate, dodecyldimethylethylammonium bromide, tetradecyltrimethylammonium bromide and benzyldimethyldodecylammonium bromide were made at different temperatures. On the basis of the obtained results the activity of the surfactants at the water–air interface was determined and discussed based on the intermolecular interactions. The surfactant activity at the water–air interface was taken into account for determination of thermodynamic parameters of surfactant adsorption using the Langmuir method and the Szyszkowski equation. The thermodynamic parameters were also determined by means of the Rosen and Aronson, Gamboa and Olea methods as well that based on the changes of tail–water interface tension to that of tail–air.

Significant effect of polar head group of surfactants on the solubilization of Zein in mixed micellar (SDS–DDAB) media

In recent years, the ability of ionic surfactants such as sodium dodecyl sulfate (SDS) to solubilize the water-insoluble protein Zein in aqueous solution, referred to as the Zein solubilization test, has been investigated to rank the skin irritation potential and protein denaturation potential of surfactants. However, the potential of cationic surfactants towards solubilization of Zein has not been explored much. In present report, the effect of the concentration of cationic surfactant, dodecylethyldimethylammonium bromide (DDAB) on Zein solubilization in the presence of anionic surfactant, SDS has been investigated. It has been observed that the solubilization of the Zein protein induced by SDS is affected by the presence of DDAB. The electrostatic and hydrophobic interactions between two surfactants are the deciding factors for the solubilization of Zein. The estimated values of critical aggregation concentration (cac) and critical micellization concentration (cmc) indicate that the association of Zein with SDS–DDAB takes place at somewhat higher concentration than with SDS. Fluorescence study reveals the more hydrophobic environment for the pyrene in SDS–DDAB in Zein than SDS–DDAB in water. The aggregation behavior of mixed surfactants in the presence of protein has also been analyzed. Thermodynamic study of the colloidal behavior of mixed surfactants depicts that at higher temperature enthalpy factor as well as entropic factor increases however, increase in entropy dominates over enthalpy factor.

Behavior of papain in mixed micelles of anionic–cationic surfactants having similar tails and dissimilar head groups

The mixed micellar behavior of anionic surfactant, sodium dodecylsulfate (SDS) and cationic surfactant, dodecylethyldimethylammonium bromide (DDAB) at varying mole fractions of DDAB, i.e. α DDAB in aqueous solution of papain has been investigated with the aid of spectroscopy and physiochemical measurements. Thermodynamic parameters have been computed over the entire mole fraction range of DDAB. The Clint equation and the regular approximation method have been used to investigate the interactions between mixed surfactants in the presence of protein. The two surfactants have similar tails, however, the charges on respective polar head groups are expected to have significant effect on their colloidal behavior. The cmc values of mixed surfactants have been estimated from fluorescence, conductivity, surface tension, ultrasonic speed and density measurements. The results show that lower and higher mole fractions of DDAB give negative departure from ideality whereas intermediate mole fractions have positive deviation. The aggregation number, N agg of mixed micelles has also been calculated. The turbidity or cloudiness at intermediate mole fractions demonstrates a reduction in the background free monomer concentration due to neutralization of the monomers of opposite charge. The effect of concentration of papain on mixed micellar behavior indicates that with increase in the concentration of protein, the cac and cmc values increase. The unfolding of polypeptide chain in the presence of mixed surfactant has been observed.

Solubilization and conformational behavior of Zein in aqueous solution of dodecyldimethylethylammonium bromide (DDAB)

The solubilization and conformational behavior of Zein in the presence of cationic surfactant, dodecyldimethylethylammonium bromide (DDAB) have been studied. The colloidal properties of DDAB in the absence and presence of Zein have also been investigated using physico-chemical and spectroscopy methods. The surfactant appears to bind to Zein at concentrations below the critical micelle concentration (cmc) and the binding becomes weaker at concentrations above the cmc. The interaction between DDAB and Zein depends on the chemical structure and molecular parameters (conformation, molar mass, charge) of the protein. The schematic sketches of the molecular mechanisms of the complex formation between like-charged proteins and surfactants have been proposed.

Surface and volume properties of dodecylethyldimethylammonium bromide and benzyldimethyldodecylammonium bromide: I. Surface properties of dodecylethyldimethylammonium bromide and benzyldimethyldodecylammonium bromide

Surface tension measurements were carried out for aqueous solutions of two cationic surfactants: dodecylethyldimethylammonium bromide (C 12(EDMAB)) and benzyldimethyldodecylammonium bromide (BDDAB). Isotherms and thermodynamic adsorption parameters were determined from the surface tension data. Firstly, the surface excess concentration in the adsorbed monolayer and the total concentration of the surfactants were determined, then the standard free energy of adsorption was calculated by different methods. In the calculations, different orientations of the surfactants at the adsorbed monolayer were also taken into account. From the experimental and calculated data it results that the difference in the structure of the two cationic surfactants by changing the methyl group for aryl one in their heads causes an increase of the efficiency and a decrease of the effectiveness of adsorption at water–air interface, and that the standard free energy of adsorption can be predicted from the surface tension of the surfactants assuming the aryl group to be equivalent to 3.5 methylene groups. The experimentally obtained difference between the standard free energy of adsorption of the C 12(EDMAB) and BDDAB was in good agreement with that theoretically accounted, corresponding to the standard free energy of adsorption of the aryl group. However, the best correlation between the values was obtained when a parallel orientation of the surfactant molecules at the adsorbed monolayer was taken into account.

Surface and volume properties of dodecylethyldimethylammonium bromide and benzyldimethyldodecylammonium bromide: II. Volumetric properties of dodecylethyldimethylammonium bromide and benzyldimethyldodecylammonium bromide

Density measurements were carried out for aqueous solutions of two cationic surfactants: dodecylethyldimethylammonium bromide (C 12(EDMAB)) and benzyldimethyldodecylammonium bromide (BDDAB). On the basis of the obtained results of the measurements the CMC and partial molar volumes of the surfactants studied were also determined. The obtained CMC values were also analyzed with those accounted on the basis of the surface tension data from the previous paper [J. Harkot, B. Jańczuk, J. Colloid Interface Sci. (2008), submitted for publication]. The values of CMC determined from the surface tension and density measurements for C 12(EDMAB) are equal to 9.9 × 10 −3 and 1.5 × 10 −2 M and for BDDAB to 5.25 × 10 −3 and 5.3 × 10 −3 M , respectively. These obtained values are very similar. However, in the literature it is difficult to find the CMC values for C 12(EDMAB) and BDDAB determined by these two methods used by us—especially from the density measurements for BDDAB and surface tension measurements for C 12(EDMAB). In the case of the apparent molar volumes of C 12(EDMAB) there is a good agreement between the values obtained by us and those found in the literature. The CMC values for C 12(EDMAB) and BDDAB were also determined on the basis of their surface tension and free energy of electrostatic interactions between the polar heads of these surfactants and compared with those obtained from the surface tension and density measurements. It was found that the theoretically obtained CMC values were close to those determined from the density and surface tension data for the C 12(EDMAB) and that the ratios of the CMC values of the surfactants to their concentration at which the water surface tension decreased by about 20 mN/m proved that the presence of the aryl group in the BDDAB head instead of the methyl group caused that its micellization process was more inhibited in relation to its adsorption at air–water interface than that of C 12(EDMAB).

The role of adsorption of dodecylethyldimethylammonium bromide and benzyldimethyldodecylammonium bromide surfactants in wetting of polytetrafluoroethylene and poly(methyl methacrylate) surfaces

The role of adsorption of dodecylethyldimethylammonium bromide (C12(EDMAB)) and benzyldimethyldodecylammonium bromide (BDDAB) at water–air and polytetrafluoroethylene (PTFE)–water and poly(methyl methacrylate) (PMMA)–water interface, in wetting of PTFE and PMMA surface, was established from the measured values of the contact angle (θ) of aqueous C12(EDMAB) and BDDAB solutions in PTFE (PMMA)-solution drop–air system, and from the measured values of the surface tension of aqueous C12(EDMAB) and BDDAB solutions. Adsorption of C12(EDMAB) and BDDAB at water–air interface was determined earlier from the Gibbs equation. Adsorption at solid–water interface was deduced from the Lucassen-Reynders equation based on the relationship between adhesion tension (γLVcosθ) and surface tension (γLV). The slope of the γLVcosθ–γLV curve was found to be constant and equal to −1, and about −0.3 for PTFE and PMMA surface, respectively (in the case of both surfactant studied: C12(EDMAB) and BDDAB, and in the whole range of surfactants concentration in solution). It means that the amount of the surfactant adsorbed at the PTFE–water interface, ΓSL, was essentially equal to its amount adsorbed at water–air interface, ΓLV. However, ΓSL at the PMMA–water interface was about three times smaller as compared to that at water–air interface. By extrapolating the linear dependence between γLVcosθ–γLV and dependence between cosθ–γLV and cosθ=1 we determined the value of the critical surface tension of PTFE and PMMA surface wetting, γc. The obtained values of γc for PTFE surface were equal 23.4 and 23.8mN/m, 23.1 and 23.2mN/m for C12(EDMAB) and BDDAB, respectively and they were higher than the surface tension of PTFE (20.24mN/m). On the other hand, the obtained values of γc for PMMA surface were equal 31.4 and 30.9mN/m, 31.7 and 31.3mN/m for C12(EDMAB) and BDDAB, respectively and they were smaller than the surface tension of PMMA (39.21mN/m). Using the values of PTFE and PMMA surface tension and the measured values of the surface tension of aqueous C12(EDMAB) and BDDAB solutions in the Young equation, the PTFE (PMMA)-solution interfacial tension, γSL, was also determined. Next, the work of adhesion (WA) was deduced, and it occurred that the dependence between the WA and the surface tension (γLV) for both studied solids was linear. However, the values of the WA for PMMA change as a function of logC (C—surfactant concentration) changed from 91.7 to 68.5mJ/m2 and from 91.8 to 65.1mJ/m2 for C12(EDMAB) and BDDAB, respectively. On the other hand, the work of adhesion of both studied surfactants solutions to the PTFE surface was practically constant (an average value was equal 45.8 and 45.4mJ/m2, respectively). These values were close to the value of the work of water adhesion to PTFE surface (45.5mJ/m2).