Diversity In Asia Research Articles

Chemometrics-based analysis of the phytochemical profile and antioxidant activity of Salvia species from Iran

In recent years, the exploration of the therapeutic potential of Salvia has gained considerable attention, leading to a growing number of scientific studies emphasizing its pharmacological properties. Despite this, therapeutic applications of Salvia remain underexploited, requiring further investigation. Iran is a major center for sage diversity in Asia, boasting 60 Salvia species, 17 of which are unique to the area. This study aimed to comprehensively explore and compare the extracts of 102 Salvia samples belonging to 20 distinct Salvia species from Iran, providing a deeper understanding of their specific polyphenol content and, consequently, their antioxidant capabilities and potential therapeutic uses. All samples were analyzed to determine the contents of total phenolics, total flavonoids, total tannin, photosynthetic pigments, and ascorbic acid, along with their antioxidant activity. These data were then combined with the forty distinct chemical fingerprints identified by ultrafast high-pressure liquid chromatography coupled with high-resolution mass spectrometry. Multivariate data analysis was employed to find correlations and differences among the huge number of data obtained and to identify Salvia species with similar phytochemical and/or antioxidant properties. The results show that each Salvia species is characterized by a distinct class of polyphenols recognized for their antidiabetic, anti-inflammatory, cardioprotective and neuroprotective properties. Overall, our findings reveal the potential of some Salvia species for targeted therapeutic applications and provide a rational basis for the development of Salvia-derived nutraceuticals, ultimately improving the prospects for the use of Salvia in medicine.

An integrative taxonomy of Asian Caryodaphnopsis (Lauraceae) based on morphology and phylogenomics

AbstractCaryodaphnopsis is a small genus of the Lauraceae family with disjunct distribution in tropical Asia and tropical America. Taxa from each region form a well­supported monophyletic clade. However, the species circumscription in Asian Caryodaphnopsis remains ambiguous due to few and generally unstable morphological characters used for classification. To address this, we conducted an integrative taxonomy of the Asian clade. We investigated 13 populations, sampled 57 accessions covering the entire taxonomic diversity, geographic range, and morphological variation in Asia, and reconstructed a new phylogeny using single‐nucleotide polymorphisms. We obtained a well‐resolved phylogeny of the Asian Caryodaphnopsis. The first diverged clade consists of three species endemic to lowland forests. The second (largest) clade (eight species in total) mainly occurs in limestone mountain forests and has a double‐layered lower leaf epidermis morphology of type 2 (less complete roomy with closed “roof”) and type 3 (complete roomy with closed “roof”). Based on the diagnostic morphological characters, distinct distributional ranges, and monophyly of each clade, we recognize 12 species in the Asian Caryodaphnopsis, including three new species: C. cangyuanensis sp. nov., C. hekouensis sp. nov., and C. rubrinervis sp. nov. We also reinstate C. latifolia, and re‐circumscribe the widespread C. tonkinensis and other species based on fruit and inflorescence morphology and molecular evidence.

Gastronomic Tourism: Experiencing a Region's Identity through Modern Cuisine in Asia

The culinary diversity in Asia affects the interest of tourists to visit, this is a fascinating thing to explore. This study investigate the role of gastronomy tourism in expressing and communicating the identity of a region. This study use descriptive qualitative method, it explains how to understand research subject phenomena, behavior, perceptions, motivations, actions, and so on, holistically, and how to describe the results in the form of words and sentences (Moleong: 2010). Using the theory of gastronomic identity proposed by Harrington (2005), researchers analyze that Authenticity is the representation of traditional culinary traditions that reflect a region's historical and cultural foundations. Diversity includes the variety of ingredients, recipes, and culinary skills in a region, Innovation is the imaginative modification and advancement of conventional cooking techniques to suit modern preferences and fads. And sustainable food practices prioritize social responsibility and environmental friendliness in the case of five countries in Asia : China, Indonesia, India, Turkey, Kazakhstan. Gastronomy tourism can be found as a powerful tool for promoting a region's identity, both to locals and tourists.

Aquaculture production and diversification: What causes what?

Aquaculture, an important source of food supply, is expected to be the main sector to satisfy growing seafood demand in the future. Being the most diversified food product in the world, aquaculture diversification can add resilience to global food security, satisfy consumer preferences, and promote price stability. Understanding the relationships between aquaculture production and diversification and their causations is crucial for developing effective strategies to support long-term sustainability and resilience of aquaculture development. This study investigates the direction of causal relationships between aquaculture production and diversification using a panel vector autoregression (PVAR) model with three decades of aquaculture production data and the Effective Number of Species (ENS) values by country. Diversification is measured in terms of within-group diversity (ENSα) and between-group diversity (ENSβ); this approach provides deeper insights into diversification strategies. The model results show that between-group diversification is more conducive to production expansion globally, especially in the Americas and Asia, and the positive effects are long lasting. Within-group diversification also induces more production in Europe and, to a lesser extent, in Asia. Therefore, policies and market incentives that promote diversification across different species groups in the Americas and Asia, and diversification within the same species group in Europe and Asia, are potential strategies to expand aquaculture production. Other findings include production leading within-group diversification in Asia and Europe, but not in the Americas and Africa. A possible explanation is that production expansion would accumulate experience, develop scope economies and emerging technologies, and build up capacities. These factors generate spillover effects that facilitate species diversification, considering that Asia and Europe have a longer history of aquaculture development compared to the Americas and Africa. However, no significant relationship is found indicating production leading between-group diversification.

Toxoplasma gondii Genotypes Isolated from Humans: A Systematic Review

Toxoplasma gondii has the capacity to infect several animals, including humans. This parasite has great genetic variability due to crossing over in felines’ gut. These new atypical and exotic genotypes are complex, requiring genotyping research to help elucidate virulence mechanisms. For the purpose of the study, five English language databases reporting data on T. gondii genotyping in humans were searched. The searching process resulted in the inclusion of 28 articles published from 2000 to September 2020. The data revealed that 1,167 samples were genotyped into 470 T. gondii isolates. In the world, type II was predominant (53.65%, n = 257). Atypical genotypes were the second most common (22.33%, n = 107). The results suggest greater genetic diversity in Asia and America than in the European and African continents. The genotype #9 was prevalent in Asia. Furthermore, atypical strains were predominant in 50 isolates from patients with ocular toxoplasmosis (52%, n = 26). In individuals with congenital toxoplasmosis, type II was predominant presenting a prevalence of 46.49% (n = 73). Type II strains were predominant in immunocompromised with a prevalence of 75.6% (n = 31). In cancer patients, there was a predominance of atypical strains with 67.14% (n = 47) and genotype #17 was specific for this group. In general, this systematic review indicated a great degree of genetic diversity and circulation of virulent T. gondii strains in humans. However, further studies are needed to better understand the population structure of T. gondii and its clinical characteristics.

Making meaning from fragmentary fossils: Early Homo in the Early to early Middle Pleistocene

In celebration of the 50th anniversary of the Journal of Human Evolution, we re-evaluate the fossil record for early Homo (principally Homo erectus, Homo habilis, and Homo rudolfensis) from early diversification and dispersal in the Early Pleistocene to the ultimate demise of H. erectus in the early Middle Pleistocene. The mid-1990s marked an important historical turning point in our understanding of early Homo with the redating of key H. erectus localities, the discovery of small H. erectus in Asia, and the recovery of an even earlier presence of early Homo in Africa. As such, we compare our understanding of early Homo before and after this time and discuss how the order of fossil discovery and a focus on anchor specimens has shaped, and in many ways biased, our interpretations of early Homo species and the fossils allocated to them. Fragmentary specimens may counter conventional wisdom but are often overlooked in broad narratives. We recognize at least three different cranial and two or three pelvic morphotypes of early Homo. Just one postcranial morph aligns with any certainty to a cranial species, highlighting the importance of explicitly identifying how we link specimens together and to species; we offer two ways of visualizing these connections. Chronologically and morphologically H. erectus is a member of early Homo, not a temporally more recent species necessarily evolved from either H. habilis or H. rudolfensis. Nonetheless, an ancestral–descendant notion of their evolution influences expectations around the anatomy of missing elements, especially the foot. Weak support for long-held notions of postcranial modernity in H. erectus raises the possibility of alternative drivers of dispersal. New observations suggest that the dearth of faces in later H. erectus may mask taxonomic diversity in Asia and suggest various later mid-Pleistocene populations could derive from either Asia or Africa. Future advances will rest on the development of nuanced ways to affiliate fossils, greater transparency of implicit assumptions, and attention to detailed life history information for comparative collections; all critical pursuits for future research given the great potential they have to enrich our evolutionary reconstructions for the next fifty years and beyond.

A new vista on Asian families and intimacies: creating common foundations for knowledge production within and on Asia

A three-level project has been carried out to fulfil the mission of creating common foundations for international research collaboration within and on Asia. The first level is the collection, translation and sharing of important research findings from Asian insider perspectives that had been published or presented in the various languages in Asia. The second is to create a common basis for empirical research by building a database for international comparison. On the third level, effective international collaborative research projects focusing on various topics are made possible. Diversity in Asia has usually been taken to mean diversity of civilisations, but, at a deeper level is found the diversity rooted in kinship structure. This layer plays particularly important roles in constructing local forms of family, gender and intimacy. On top of these, modernisation created another layer. These layers influence each other at various times and to various degrees, constructing a dynamic diversity.

The Patentability of Second and Subsequent Medical Uses in Asia’s Patent Legislation

Abstract This study examines, from a comparative law perspective, how jurisdictions across East, Southeast and South Asia deal with the issue of the patentability of second/subsequent medical uses. The Covid-19 pandemic highlighted the importance of subsequent medical uses of known medical compositions, as a number of medicines that are being used to treat Covid-19 were originally developed for other illnesses. The decision whether second/subsequent medical uses of pharmaceuticals are patentable in any given jurisdiction is, however, a policy decision to the extent that it is one of the main exclusions available to countries as a ‘flexibility’ under the World Trade Organization’s Agreement on Trade-related Aspects of Intellectual Property Rights (the TRIPS Agreement). The results of this study show that there is a wide variation in Asia regarding the patentability of second/subsequent uses, and examines the possible reasons for this variation. The paper concludes with recommendations for countries in the region.

Tropical and subtropical Asia's valued tree species under threat.

Tree diversity in Asia's tropical and subtropical forests is central to nature-based solutions. Species vulnerability to multiple threats, which affect provision of ecosystem services, is poorly understood. We conducted a region-wide, spatially explicit assessment of the vulnerability of 63 socioeconomically important tree species to overexploitation, fire, overgrazing, habitat conversion, and climate change. Trees were selected for assessment from national priority lists, and selections were validated by an expert network representing 20 countries. We used Maxent suitability modeling to predict species distribution ranges, freely accessible spatial data sets to map threat exposures, and functional traits to estimate threat sensitivities. Species-specific vulnerability maps were created as the product of exposure maps and sensitivity estimates. Based on vulnerability to current threats and climate change, we identified priority areas for conservation and restoration. Overall, 74% of the most important areas for conservation of these trees fell outside protected areas, and all species were severely threatened across an average of 47% of their native ranges. The most imminent threats were overexploitation and habitat conversion; populations were severely threatened by these factors in an average of 24% and 16% of their ranges, respectively. Our model predicted limited overall climate change impacts, although some study species were likely to lose over 15% of their habitat by 2050 due to climate change. We pinpointed specific natural areas in Borneo rain forests as hotspots for in situ conservation of forest genetic resources, more than 82% of which fell outside designated protected areas. We also identified degraded areas in Western Ghats, Indochina dry forests, and Sumatran rain forests as hotspots for restoration, where planting or assisted natural regeneration will help conserve these species, and croplands in southern India and Thailand as potentially important agroforestry options. Our results highlight the need for regionally coordinated action for effective conservation and restoration.

A Case for Value-Added Exports in the Estimation of Export Diversification in Asia and the Pacific

A Case for Value-Added Exports in the Estimation of Export Diversification in Asia and the Pacific

Spatiotemporal Evolution of the Global Species Diversity of Rhododendron.

Evolutionary radiation is a widely recognized mode of species diversification, but its underlying mechanisms have not been unambiguously resolved for species-rich cosmopolitan plant genera. In particular, it remains largely unknown how biological and environmental factors have jointly driven its occurrence in specific regions. Here, we use Rhododendron, the largest genus of woody plants in the Northern Hemisphere, to investigate how geographic and climatic factors, as well as functional traits, worked together to trigger plant evolutionary radiations and shape the global patterns of species richness based on a solid species phylogeny. Using 3,437 orthologous nuclear genes, we reconstructed the first highly supported and dated backbone phylogeny of Rhododendron comprising 200 species that represent all subgenera, sections, and nearly all multispecies subsections, and found that most extant species originated by evolutionary radiations when the genus migrated southward from circumboreal areas to tropical/subtropical mountains, showing rapid increases of both net diversification rate and evolutionary rate of environmental factors in the Miocene. We also found that the geographically uneven diversification of Rhododendron led to a much higher diversity in Asia than in other continents, which was mainly driven by two environmental variables, that is, elevation range and annual precipitation, and were further strengthened by the adaptation of leaf functional traits. Our study provides a good example of integrating phylogenomic and ecological analyses in deciphering the mechanisms of plant evolutionary radiations, and sheds new light on how the intensification of the Asian monsoon has driven evolutionary radiations in large plant genera of the Himalaya-Hengduan Mountains.

Evolutionary origin of species diversity on the Qinghai–Tibet Plateau

AbstractThe Qinghai–Tibet Plateau (QTP) sensu lato (sl) houses an exceptional species diversity in Asia. To develop a comprehensive understanding of species diversity in this fascinating region, we reviewed recent progress from biogeographic, paleogeographic, paleontological and genomic research of both plants and animals in the QTPsl. Numerous studies have been conducted to examine whether the QTPsl uplift triggered the production of rich species diversity there, whether a Quaternary “unified ice sheet” eliminated plants and animals on the central plateau and how high‐altitude species developed the extreme environment adaptations. Major disputes arose about the first issue, mainly from different understanding of the QTP circumscriptions and related uplift, inaccurate dating of molecular phylogenetic trees, and non‐causal correlations between uplift and species diversification. The QTPsl uplift is spatially and temporally heterogeneous, and abundant fossils reported recently similarly support such an asynchronous upheaval model across the entire region. Available phylogeographic studies of alpine plants and animals suggested their glacial refugia in the central QTPsl, rejecting a unified ice sheet during the Last Glacial Maximum. Genomic evidence from a limited number of alpine species has identified numerous candidate genes for high‐altitude adaptation. In the future, more studies should be focused on speciation and adaptation mechanisms of the alpine species in the QTPsl based on the cutting‐edge methods.

CSRP3, p.Arg122*, is responsible for hypertrophic cardiomyopathy in a Chinese family

Hypertrophic cardiomyopathy (HCM) is a hereditary disease manifested by a thickened ventricular wall. Cysteine and glycine-rich protein 3 (CSRP3), the gene encoding muscle LIM protein, is important for initiating hypertrophic gene expression. The mutation of CSRP3 causes dilated cardiomyopathy or HCM. In the present study, we enrolled a Chinese family with HCM across three generations. Whole-exome sequencing (WES) was performed in the proband to detect the candidate genes of the family. Sanger sequencing was performed for mutational analysis and confirmation of cosegregation. Through histopathological and imaging examinations, an obvious left ventricular hypertrophy was found in the proband. After WES data filtering, bioinformatic prediction and co-segregation analysis, a nonsense mutation (NM_003476.5:c.364C>T; NP_003467.1:p.Arg122*) of CSRP3 was identified in this family. This variant was predicted to be disease-causing and resulted in a truncated protein. This is the first HCM family case of CSRP3 (p.Arg122*) variation in Asia. The finding here not only contributes to the genetic diagnosis and counseling of the family, but also provides a new case with detailed phenotypes that may be caused by the CSRP3 variant.

Developing Asia – Dynamic but fractured

In the past seventy–five years, developing Asia has transformed more rapidly than any other region. What is behind this success? Will Asia go on to lead the world, or will its rise encounter obstacles? Asia is politically diverse, with democracies, hybrid governments and numerous authoritarian regimes. Several are unstable. Paths to prosperity have varied, including the East Asian model, China’s “socialist market economy”, Indian self–reliance, and economic transition in Central Asia. Regional cooperation is chronically weak, due to the youthfulness, dispersion and diversity of Asia’s sovereign states. China’s rise threatens to fracture the region further. As the region emerges from the Covid–19 crisis, East Asia is well positioned to lead an economic recovery. However, many challenges remain. Political and governance systems are weak. Territorial disputes could escalate into open conflict, including Taiwan. Human capital is poorly developed, and populations are aging. Finally, the region could be polarized between the United States and China.

An Evaluation of Racial Diversity in Craniofacial Surgery Literature.

Implicit bias can lead to discrimination of certain populations within healthcare. Representation in medical literature is no exception and it is hypothesized that images with lighter skin tone are more prevalent than darker skin tones in craniofacial literature. Clinical photographs and figure graphics from 5 journals were examined for pre-defined years. Annals of Plastic Surgery, Aesthetic Surgery Journal, Journal of Craniofacial Surgery, Journal of Plastic, Reconstructive and Aesthetic Surgery, and Plastic and Reconstructive Surgery journals were reviewed. All craniofacial-focused articles containing at least one color image depicting human skin were included. 10,477 images and 627 graphics were evaluated using the Fitzpatrick scale as a guide. Most journals trended toward broader inclusion of nonwhite photographs and graphics over time. In 2016, 47% of articles published in Journal of Craniofacial Surgery included nonwhite images compared to Annals of Plastic Surgery (16%), Aesthetic Surgery Journal (40%), Journal of Plastic, Reconstructive and Aesthetic Surgery (25%), and Plastic and Reconstructive Surgery (7%). Comparison of domestic and international publications demonstrated that author's country of origin impacted the percentage of nonwhite clinical photographs for most journals. Comparisons of publications by country demonstrated increased diversity in Asia and the Middle East for clinical photographs but not graphics. The frequency of nonwhite figure graphics was staggeringly low, identified in only 18 articles across all journals and years. Craniofacial literature more commonly reflects white skin tones. The trend over time suggests increasing inclusion of racial diversity in clinical photographs; however, figure graphics remain less racially diverse. Time, country of origin, and publishing journal appear to play a role.

Plastid phylogenomics and biogeography of the genus Monochoria (Pontederiaceae)

Abstract Monochoria C. Presl is a genus of Pontederiaceae and confined to the Old World, with species mainly distributed in tropical and subtropical Africa, Asia, and Australia. However, phylogenetic relationships and biogeography within Monochoria are yet to be fully resolved. Here, we sequenced 14 Monochoria plastomes, representing around eight of the ~10 species of Monochoria, and two plastomes from related genera. We undertook comparative analyses and phylogenetic reconstructions of Monochoria using these and other available sequences. We found the plastomes of Pontederiaceae to be highly conserved in structure, and identified six regions as mutational hotspots among species of Monochoria. Our data strongly support the monophyly of Monochoria and two main clades within the genus. We confirm that Monochoria australasica Ridl. is sister to the rest of the genus and that Monochoria korsakowii (Regel & Maack) defines the second split within Monochoria. In addition, we inferred the African endemic species Monochoria africana (Solms) N. E. Br. to be closely related to Monochoria plantaginea (Roxb.) Kunth and an undetermined specimen from Australia (Monochoria sp. AU63). Estimation of divergence times and biogeography implied that the African species M. africana originated in Asia, and the most recent common ancestor of Monochoria was distributed in Australasia/Asia at approximately 15 Ma, followed by diversification in Asia during the late Miocene and Pliocene. Long‐distance dispersal, likely mediated by migratory birds, to Africa and Australia during the Pliocene and Pleistocene, might have contributed to the extant transoceanic distribution of the genus. Additionally, based on our phylogenetic results, we revised the description of Monochoria valida G. X. Wang & Nagam here.

Corrigendum

Corrigendum

Prevalence and Diversity of Avian Haemosporidians May Vary with Anthropogenic Disturbance in Tropical Habitats in Myanmar

Avian malaria and related haemosporidians (genera Haemoproteus, Plasmodium and Leucocytozoon) infect most clades of bird. Although these parasites are present in almost all continents, they have been irregularly studied across different geographical regions. Despite the high bird diversity in Asia, the diversity of avian haemosporidians in this region is largely unknown. Moreover, anthropogenic changes to habitats in tropical regions may have a profound impact on the overall composition of haemosporidian communities. Here we analyzed the diversity and host association of bird haemosporidians from areas with different degrees of anthropogenic disturbance in Myanmar, revealing an unexplored diversity of these parasites (27% of newly-discovered haemosporidian lineages, and 64% of new records of host–parasite assemblages) in these tropical environments. This newly discovered diversity will be valuable for detecting host range and transmission areas of haemosporidian parasites. We also found slightly higher haemosporidian prevalence and diversity in birds from paddy fields than in individuals from urban areas and hills, thus implying that human alteration of natural environments may affect the dynamics of vector-borne diseases. These outcomes provide valuable insights for biodiversity conservation management in threatened tropical ecosystems.

Chemometrics-based LC-UV-ESIMS analyses of 50 Salvia species for detecting their antioxidant constituents

Iran is one of the main hubs for sage’s diversity in Asia. Generally, prediction and characterization of the chemical structures of the specialized metabolites that have significant role in the bioactivity of a plant remains a significant challenge. In this study, 50 different accessions of 32 Salvia species in 2015 and 2017 were collected and extracted for their phenolics, using 80 % methanol. LC-PDA-ESIMS analyses was coupled with multivariate analysis to identify the specific metabolites in the plant extracts, responsible for the antioxidant activity. Based on the variable importance in projection (VIP) method on the Genetic algorithm combined with PLS (GA-PLS) models, eighteen peaks were detected as multifunctional compounds. The putative phenolic compounds were attributed to apigenin-O-diglucoside, rutin, cynaroside, luteolin-7-O-glucoronide, apigenin-7-O-glucoside, apigenin-7-O-glucuronide, hispidulin-7-O-glucuronide, hispidulin-7-O-glucoside, rosmarinic acid, salvianolic acid B derivative, cirsimaritin, eupatorin, and carnosol. This investigation showed that the Salvia’s extract can facilitate an opportunity for rapid detection, isolation and development of antioxidant agents.

Morphological characterization of diploid and triploidAcorus calamus(Acoraceae) from southern Western Siberia, parthenocarpy in sterile plants and occurrence of aneuploidy

AbstractFinding morphological differences between cytotypes that are stable throughout their geographical range is important for understanding evolution of polyploid complexes. The ancient monocot lineage Acorus includes two groups, of which A. calamus s.l., an important medicinal plant, is a polyploid complex with a centre of diversity in Asia. European plants are sterile triploids introduced by humans. An early study suggested that plants from temperate Asia are tetraploids, but subsequent work revealed diploids and triploids rather than tetraploids in Asiatic Russia; however, cytotype diversity in Western Siberia is insufficiently known. We document the occurrence of diploids and triploids in Western Siberia. Triploids that do not differ in genome size from European Acorus are abundant in the valley of the river Ob where the ability for extensive vegetative propagation provides ecological advantages. An isolated population of aneuploid triploids with 33 chromosomes is found outside the Ob valley. Flow cytometry provides an efficient tool for identification of aneuploid plants in Acorus. All triploids are sterile, but their flowers develop uniform parthenocarpic fruits. Fruits of diploids usually vary in size within a spadix depending on the number of developing seeds. In contrast to North America, where the native diploid plants differ from the introduced triploids by the absence of a secondary midrib of the ensiform leaf blade, Siberian diploids are similar to triploids in possessing a secondary midrib. We confirm that diploids differ from triploids in the size of air lacunae in leaves, which is determined by cell number rather than cell size in septa of aerenchyma. A combination of spathe width and spadix length measured after the male stage of anthesis shows different (slightly overlapping) patterns of variation between diploids and triploids in our material.