Diverse Ethnic Groups Research Articles

The Relationship between Race, Ethnicity, and Suicidal Thoughts and Behaviors among Students at Institutions of Higher Education in the U.S.

We review the published literature on the relationship between race and ethnicity and suicidal thoughts and behaviors among students enrolled at institutions of higher education in the United States. College students with certain racial and ethnic identities have a higher prevalence of past-year suicidal ideation (Asian, Black or African American, multiracial, and Native Hawaiian or Other Pacific Islander) and past-year suicide attempts (Asian, Black or African American, multiracial, and Hispanic) than White students. There is a lack of evidence about racial and ethnic differences in suicide deaths. More research is needed to understand factors that contribute to the racial and ethnic disparities in suicidal thoughts and behaviors among college students. Identifying modifiable risk factors that may be specific to college students will ultimately reduce suicide deaths and guide the development of more effective suicide prevention programs across diverse racial and ethnic groups of students.

Public’s Visual Preferences Survey Facilitates Community-Based Design and Color Standards Creation

According to research, there is a disparity in the aesthetic design preferences of the public and architects. This is especially noticeable in urban areas environments, where there is a wide range of demographic variables and a lack of active public involvement in decision-making. The study included a visual preference survey to evaluate the perception and ranking of two dominant color schemes in local development projects in Stockholm across different age, ethnicity, and gender groups from Sweden. Over 400 people participated in the survey, which used photo-elicitation and a literature review. The objective was to determine the extent of divergence and disparities in the ranking of color schemes. The first dominant color schemes are a group of four analogous colors related to the Natural Color System’s (NSC’s) basic colors. The second is a group of four neutral colors that are related to grayscale colors. The study demonstrates that one could also measure building color schemes using visual preference ranking. Moreover, the research introduced a unique method for city planners to understand diverse ethnic, gender, and age group perceptions of color schemes in current projects, promoting active participation in decision-making and providing valuable insights. These insights can enhance people’s sense of belonging, a prerequisite for social sustainability, and improve the quality and profitability of future projects.

IRF5 Variants Are Risk Factors for Systemic Lupus Erythematosus in Two Mexican Populations.

Interferon regulatory factor 5 ( IRF5 ) is one of the pivotal genes implicated in systemic lupus erythematosus (SLE) among diverse ethnic groups, including Europeans, Asians, Hispanics, and Africans. Notably, its significance appears particularly pronounced among Hispanic populations. Previous studies have identified several single-nucleotide variants within IRF5 , such as rs2004640G/T, rs2070197T/C, and rs10954213G/A, as associated with susceptibility to SLE among patients from Mexico City. However, the population of Yucatan, located in the Southeast of Mexico and characterized by a greater Amerindian genetic component, remains largely unexplored in this regard. Our study aimed to replicate the observed association between IRF5 variants and susceptibility to SLE among patients from Central Mexico and Yucatan. Furthermore, we investigated the impact of IRF5 rs59110799G/T, a variant that has not been previously studied in SLE individuals. Our study included 204 SLE patients and 160 controls from Central Mexico, as well as 184 SLE patients and 184 controls from Yucatan. All participants were females 18 years and older. We employed a TaqMan assay to detect the presence of the following single-nucleotide variants: rs2004640G/T, rs2070197T/C, rs10954213G/A, and rs59110799G/T. Furthermore, we utilized 2 distinct web tools and databases to predict the potential functional implications of IRF5 variants. In SLE patients from Central Mexico, several IRF5 alleles showed significant associations with the disease following adjustment by the Bonferroni test: the rs2070197C allele (odds ratio [OR], 2.08), the rs10954213A allele (OR, 1.59), and the rs59110799G allele (OR, 1.71). Conversely, among patients from Yucatan, the following alleles showed associations: rs2004640T (OR, 1.51), rs2070197C (OR, 1.62), rs10954213A (OR, 1.67), and rs59110799G (OR, 1.44). Our findings highlight genetic variations between Mexican populations and emphasize the role of IRF5 as a risk factor in SLE patients from both Central Mexico and Yucatan.

Genome-wide association study and polygenic risk score analysis for schizophrenia in a Korean population

Although large-scale genome-wide association studies (GWASs) have revealed the genetic architecture of schizophrenia, these studies have mainly focused on populations of European ancestry. This study aimed to identify common genetic variants associated with schizophrenia in the Korean population and evaluate the performance of polygenic risk scores (PRSs) derived from large-scale GWASs across ancestries. In the Korean psychiatric GWAS project (KPGP), seven academic institutes and their affiliated hospitals across South Korea recruited a cohort of 1670 patients with DSM-IV-defined schizophrenia and 2271 healthy controls. A total of 6690,822 SNPs were tested for association with schizophrenia. We identified one previously unreported genome-wide significant locus rs2423464 (P = 2.83 × 10−11; odds ratio = 1.65; 95 % confidence interval = 1.43–1.91, minor allele frequency = 0.126). This variant was also associated with increased lysosomal-associated membrane protein family member 5 (LAMP5) gene expression. The PRS derived from the meta-analysis results of East Asian and European GWASs explained a larger proportion of the phenotypic variance in the Korean schizophrenia sample than the PRS of an East Asian or European GWAS. (R2 = 0.073 for meta-analysis; 0.028 for East Asian GWAS; 0.037 for European GWAS). GWASs involving diverse ethnic groups will expand our understanding of the genetic architecture of schizophrenia.

The Roma Population: Migration, Settlement, and Resilience

The Roma population—with a unique history marked by migration, settlement issues, and ongoing resilience—has always faced significant social marginalization and has often been subjected to forced migration. Despite being one of the largest and most diverse ethnic groups in Europe, Roma continue to face systemic discrimination and social exclusion, leading to poor outcomes in education, employment, health, and housing. This article analyses the migration pathways, settlement experiences, and persistent obstacles faced by Roma. We argue that removing historical and systemic barriers to create a more equitable and welcoming environment for the Roma community is their right. The resilience of the Roma community in the face of adversity is a testament to their cultural strength and adaptability. This research aims to document these aspects and thus provide a basis for policies that promote social inclusion, equality, and respect for cultural diversity.

Exploring opportunities and challenges in promoting interethnic tolerance as a social good through virtual influencers

Purpose This paper aims to understand how virtual influencers (VIs) can promote interethnic tolerance, online, among youth as a social good. Design/methodology/approach This paper conducted qualitative research using interpretive analysis with RTA (Reflexive Thematic Analysis) on data collected through focus groups. Findings This paper revealed that the quality of the VI’s content is a leading factor influencing VI's ability to promote interethnic tolerance, but creating content that is constantly authentic, appealing and inclusive to diverse ethnic groups in a particular context is challenging. Research limitations/implications The study has some limitations related to the specific context on which it is focused and therefore transferring the findings to different contextual conditions requires caution, and also can be extended with positivist validation. Practical implications Findings from our study can drive future projects where real VI artifacts will play the role of a mediator in building strong relational trust among youth belonging to different ethnic groups. The findings indicate that VIs can be effectively used to foster interethnic tolerance if involve diverse team members who understand the ethnic culture deeply and social media experts, to create high-quality content to overcome some limitations. Social implications VIs can be used as social interventions to promote interethnic tolerance and to reduce prejudices and anxiety in online youth communication. Originality/value To the best of the authors’ knowledge, no known studies investigated the potential of VIs for promoting interethnic tolerance among ethnically diverse youth groups. Hence, this study paves the way for further refinement on using cutting-edge technology for social good, since it is highly challenging, often resulting in wasted money.

Worldwide analysis of actionable genomic alterations in lung cancer and targeted pharmacogenomic strategies

Based on data from the Global Cancer Statistics 2022, lung cancer stands as the most lethal cancer worldwide, with age-adjusted incidence and mortality rates of 23.6 and 16.9 per 100,000 people, respectively. Despite significant strides in precision oncology driven by large-scale international research consortia, there remains a critical need to deepen our understanding of the genomic landscape across diverse racial and ethnic groups. To address this challenge, we performed comprehensive in silico analyses and data mining to identify pathogenic variants in genes that drive lung cancer. We subsequently calculated the allele frequencies and assessed the deleteriousness of these oncogenic variants among populations such as African, Amish, Ashkenazi Jewish, East and South Asian, Finnish and non-Finnish European, Latino, and Middle Eastern. Our analysis examined 117,707 variants within 86 lung cancer-associated genes across 75,109 human genomes, uncovering 8042 variants that are known or predicted to be pathogenic. We prioritized variants based on their allele frequencies and deleterious scores, and identified those with potential significance for response to anti-cancer therapies through in silico drug simulations, current clinical pharmacogenomic guidelines, and ongoing late-stage clinical trials targeting lung cancer-driving proteins. In conclusion, it is crucial to unite global efforts to create public health policies that emphasize prevention strategies and ensure access to clinical trials, pharmacogenomic testing, and cancer research for these groups in developed nations.

Nyalamaq Dilauq tradition: A cultural policy for promoting social integration and cohesion in coastal communities

This study explores the Nyalamaq Dilauq tradition in Tanjung Luar, South Lombok, examining its role as a cultural policy for promoting social integration and cohesion in coastal communities. The Nyalamaq Dilauq tradition, deeply embedded in the lives of Tanjung Luar residents, serves as a powerful mechanism for fostering a harmonious and united community despite ethnic and cultural diversity. Through a qualitative approach involving interviews, participatory observations, and documentation, the research delves into the historical context, rituals, and ceremonies of the tradition, highlighting its significance in building social bonds and mutual respect among diverse ethnic groups. The findings reveal that the Nyalamaq Dilauq tradition enhances community resilience, supports economic interdependence, and attracts tourism, thereby contributing to the overall well-being of the coastal communities. This study provides valuable insights into the potential of cultural traditions to serve as models for social integration in other multicultural and multi-ethnic contexts.

BUILDING HISTORICAL AND CULTURAL AWARENESS THROUGH SOCIAL STUDIES LEARNING BASED ON CULTURAL EXHIBITION PROJECTS

Abstract The aim of this study is to enhance the historical and cultural awareness of students in the Social Studies Education program by creatively incorporating local wisdom values through a cultural exhibition project. The research method used was descriptive qualitative, which involved observation, interviews, and documentation of Social Studies Education students at IPI Garut. The findings of this study suggest that implementing social studies learning through cultural exhibition projects has enabled students to gain a more concrete understanding and knowledge, resulting in a more meaningful learning experience. This significance was evident in the students' increased awareness of the significance of understanding the history and culture of diverse ethnic groups in Indonesia, as well as the local wisdom values that contribute to the nation's prosperity and diversity. Furthermore, the process of creating various works for the cultural exhibition project has enabled students to develop new abilities and has inspired them to create more creative social studies learning media. It is hoped that these skills will be beneficial when the students enter the education field, both during their teaching practice and in their future careers as educators. Key words : Historical Awareness, Cultural Awareness, Social Studies Learning, Cultural Exhibition Project

The nexus between ecology of foraging and food security: cross-cultural perceptions of wild food plants in Kashmir Himalaya

BackgroundWild food plants (WFPs) play an important role in the traditional dietary habits of various indigenous communities worldwide, particularly in mountainous regions. To understand the dynamics of food preferences, cross-cultural studies on food plants should be conducted across diverse ethnic groups in a given area. In this context, the current study investigated the use of WFPs by seven different cultural groups in the Kashmir Himalayan Region. In this area, people gather wild plants and their parts for direct consumption, traditional foods, or sale in local markets. Despite this reliance, documentation of the food system, especially concerning WFPs, is notably lacking. Hence, our research aimed to document WFPs, along with associated traditional ecological knowledge, and identify major threats to their long-term sustainability in Division Muzaffarabad.MethodsThrough a comprehensive approach involving questionnaires, interviews, focus groups, and market surveys, we gathered data from 321 respondents. PCA was performed to analyze threats and plant use using “factoextra” in R software. Origin Pro was used to create a chord diagram, while R software was used to generate a Polar heat map. Additionally, a Venn diagram was created using Bioinformatics software.ResultsThe study included 321 informants, of whom 75.38% were men and 24.61% were women. In total, 113 plant taxa from 74 genera and 41 botanical families were reported. Polygonaceae and Rosaceae accounted for the majority (17 species each), followed by Lamiaceae (7 species). Leaves were the most used part as food sources (41.04%), followed by fruits (33.33%). Most of the species are consumed as cooked (46.46%) and as raw snacks (37.80%). A total of 47 plant species were collected and cooked as wild vegetables, followed by 40 species used as fruits. This study is the first to describe the market potential and ecological distribution of WFPs in the study area. Cross-comparison showed that utilization of WFPs varies significantly across the region and communities, including their edible parts and mode of consumption. Jaccard index (JI) value ranged from 5.81 to 25. Furthermore, the current study describes 29 WFPs and 10 traditional food dishes that have rarely been documented in Pakistan's ethnobotanical literature. Climate change, invasive species, expansion of agriculture, and plant diseases are some of the most significant threats to WFPs in the study area.ConclusionsThe older age group has more knowledge about WFPs compared to the younger generation, who are not interested in learning about the utilization of WFPs. This lack of interest in information about WFPs among the younger generation can be attributed to their limited access to markets and availability of food plants in the study area. Traditional gathering of food plants has been reduced in younger generations during recent years; therefore, it is crucial to develop effective conservation strategies. These efforts not only safeguard indigenous flora, food knowledge, and cultural heritage, but they also contribute to food security and public health by utilizing local wild foods in the examined area.

The Tradition of Motayok Traditional Ceremonies in Cultural Heritage Management

The traditional celebrations of Indonesia exhibit a wide range of variations, reflecting the diverse ethnic groups present in the country. One such custom is the practice of Motayok traditional rites. The Mentayok traditional ritual in cultural heritage management is rooted in the belief in supernatural forces that are believed to have the power to heal diseases and safeguard the tribe from different plagues. The ceremony follows a ritualistic musical dance, accompanied by singing, that induces a trance-like state in the dancer, allowing them to invoke spirits. This ceremony has been practiced since the 1600s. The Mokokapoi is responsible for summoning spirits while also serving as the guide during the ceremony. Typically, Mokokapoi is the spouse of the lady selected to be possessed. Totenden, as a mediator and supporter of the ritual, will join Bolian in singing the Bandit (song verses). Motayok's vocal performance and choreography will be enhanced by the rhythmic resonance of gongs and the skillful manipulation of dreadlocks by Mototobog. The Motayok traditional ceremony is seen as a form of double god or shirk. Presently, the Motayok traditional ceremony is exclusively observed in Bilalang Bersatu Village and Tudu Aog Village. There should be no necessity for the eradication of this heritage. Motayok, traditionally perceived as a mystical rite dedicated to deity veneration, is, in fact, a variant of psychotherapeutic intervention.

Regions of Homozygocity size patterns among diverse ethnic groups in Israel: Toward tailored diagnostic reporting thresholds.

Long contiguous stretches of homozygosity or regions of homozygosity (ROH) are frequently detected via microarray and sequencing technologies. However, consensus on the establishment of specific size cutoffs for reporting ROH remains elusive. This study aims to assess the Total ROH Percentages (TRPS) and size of ROH segments across different ethnic origins, exploring potential disparities and proposing tailored diagnostic thresholds. This retrospective study included 13,035 microarray analyses conducted between 2017 to 2023. ROH segments on autosomal chromosomes were retrieved, and samples lacking ROH segments were excluded. The cohort was categorized based on reported ethnic origins, and TRPS and ROH segment size were analyzed for each origin. Distinct TRPS values were noted among different ethnic groups, ranging from median 0.36% in Ethiopian Jewish cohort and up to 6.42% in the Bedouin population. Wide range of 99th percentiles of ROH segment size for various origins was noted, ranging from 10.6 to 51.5 Mb. A significant correlation between ROH segment sizes and TRPS was noted in each origin. Statistically significant differences in ROH segment sizes were noted between the Jewish and the Israeli Arab/Druze origins in TRPS from 1% to 9.99%, whereas extremities of low (0.11%-0.99%) and high (over 10%) TRPS yielded no significant differences. In conclusion, as fixed absolute size thresholds may overlook pathogenic segments in certain populations while generating excessive reports in others, tailored approaches to define ROH reporting thresholds can be considered to facilitate the accuracy and clinical relevance of genomic analyses.

Molecular monitoring of myelodysplastic neoplasm: Don't just watch this space, consider the patient's ancestry.

The heterogeneity of Myelodysplastic Neoplasm (MDS) extends beyond mutational diversity to include significant ethnic variability, a factor that has been underexplored. While the development of the IPSS-M prognostic tool has advanced our understanding of MDS, its reliance on data primarily from European cohorts limits its applicability to non-European populations. Duployez etal.'s review highlighted the importance of molecular markers in MDS for personalized treatment and disease monitoring yet did not address the impact of genetic ancestry. This commentary critiques the IPSS-M's limited sample of 110 Brazilian patients, questioning its adequacy in reflecting the influence of patient ancestry on prognostic accuracy. Given the potential for differing mutation profiles and prognostic implications across diverse ethnic groups, robust genomic ancestry studies are urgently needed. These studies should stratify MDS patients by ethnic background to investigate mutation incidence and impacts, thereby validating IPSS-M and potentially identifying new prognostic markers. Incorporating ethnic diversity into prognostic models is essential for ensuring they are truly universal and inclusive, thereby improving personalized treatment and care for all MDS patients. Commentary on: Duployez and Preudhomme. Monitoring molecular changes in the management of myelodysplastic syndromes. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19614.

Generalizing the Results of Clinical Trials if Participants Are Not From Diverse Racial and Ethnic Groups.

Generalizing the Results of Clinical Trials if Participants Are Not From Diverse Racial and Ethnic Groups.

AI-Based Visual Early Warning System

Facial expressions are a universally recognised means of conveying internal emotional states across diverse human cultural and ethnic groups. Recent advances in understanding people’s emotions expressed through verbal and non-verbal communication are particularly noteworthy in the clinical context for the assessment of patients’ health and well-being. Facial expression recognition (FER) plays an important and vital role in health care, providing communication with a patient’s feelings and allowing the assessment and monitoring of mental and physical health conditions. This paper shows that automatic machine learning methods can predict health deterioration accurately and robustly, independent of human subjective assessment. The prior work of this paper is to discover the early signs of deteriorating health that align with the principles of preventive reactions, improving health outcomes and human survival, and promoting overall health and well-being. Therefore, methods are developed to create a facial database mimicking the underlying muscular structure of the face, whose Action Unit motions can then be transferred to human face images, thus displaying animated expressions of interest. Then, building and developing an automatic system based on convolution neural networks (CNN) and long short-term memory (LSTM) to recognise patterns of facial expressions with a focus on patients at risk of deterioration in hospital wards. This research presents state-of-the-art results on generating and modelling synthetic database and automated deterioration prediction through FEs with 99.89% accuracy. The main contributions to knowledge from this paper can be summarized as (1) the generation of visual datasets mimicking real-life samples of facial expressions indicating health deterioration, (2) improvement of the understanding and communication with patients at risk of deterioration through facial expression analysis, and (3) development of a state-of-the-art model to recognize such facial expressions using a ConvLSTM model.

Factors Affecting Socio-Economic Status of the Residents of Mbeere North; Embu County Kenya

Mbeere North, a rural constituency in Embu County, Kenya, faces significant socio-economic challenges despite its potential for agricultural productivity and resource utilization. The region, inhabited predominantly by the Mbeere community and characterized by diverse ethnic groups, suffers from inadequate infrastructure, limited access to quality healthcare and education, and a reliance on subsistence farming. These issues are exacerbated by environmental degradation and climate change, leading to high poverty rates and economic instability. This study assessed the socio-economic status of Mbeere North's residents by identify the factors influencing their well-being. The research employed a descriptive design, targeting a sample of 150 residents, including households, community leaders, business owners, and providers of education and healthcare. Data collection methods included questionnaires and interviews, with a focus on key areas such as infrastructure, health, education, and economic activities. The findings revealed a population with low levels of education, limited healthcare access, and average monthly household incomes of KES 15,000. Infrastructure development is rated moderately, with significant variability in perceptions among respondents. The theoretical framework integrated Gary Becker's Human Capital Theory and Structural Functionalism. The paper presents analysis of descriptive statistics on socio-economic indicators, alongside the results of regression analysis. This analysis sheds light on the relationships between various independent variables, including education, health, economy, infrastructure, social services, and welfare, and the dependent variable, socio-economic status. Regression analysis revealed a strong positive correlation between the independent variables (education, healthcare, and infrastructure) and socio-economic status, with an R value of 0.75 and an R Square of 0.5625. In conclusion, Mbeere North requires targeted interventions to improve infrastructure, diversify agriculture, and enhance healthcare and education services. Recommendations include promoting agro-processing industries, investing in modern farming techniques, and developing eco-tourism. These strategies are essential for fostering economic growth, improving living standards, and achieving sustainable development in the region. Keywords: Effects of Socio-Economic Status on the Residents of Mbeere North; Embu County Kenya.

First report of an Ivorian family with nonsyndromic hearing loss caused by GJB2 compound heterozygous variants.

The primary etiology of congenital hearing loss is attributed to genetic factors, with GJB2 identified as a pivotal gene across diverse ethnic groups. Additionally, nonsyndromic hearing loss is predominantly inherited in an autosomal recessive manner. We used Sanger sequencing to analyze GJB2 in 17 deaf children from 13 unrelated Ivory Coast families. One family had two children born with severe congenital deafness and exhibited pathogenic compound heterozygous variants. These variants included a nonsense substitution (c.132G>A or p.Trp44Ter) and a newly discovered duplication of 7 base pairs (c.205_211dupTTCCCCA or p.Ser72ProfsTer32). Segregation testing confirmed these variants, marking the first identification of GJB2 in an Ivorian family with congenital hearing loss.

Enhancing community engagement, public involvement, and social capital through researchers’ participation in community dance projects: unexpected outcomes in underserved communities

BackgroundThe Dance and Health project aimed to promote public involvement in health research. Public involvement leads worked with project partner community groups, Aakash Odedra Dance Company and Moving Together, to develop a community engagement project with people living in low-socioeconomic areas/deprivation and diverse ethnic minority groups. Dance and Health included a weekly 60-min dance class and 30 min of facilitated health science discussion, that could either be a public involvement discussion for a research project, an activity about a particular biomedical research theme or ongoing discussions with a visiting researcher. The goal of this paper is to explore the impact of the Dance and Health project on the social capital of participants and provide key learnings on how to engage and build partnerships with people from underserved groups in health research contexts.MethodsQualitative interviews and focus groups were completed which explored participant and dance tutor experiences in community venues. Participants were aged between 22 and 90, most were female and were from Asian ethnic minority groups and White British groups living in deprived neighbourhoods in Leicester. Qualitative data were analysed using qualitative content analysis.ResultsThe responses to the Dance and Health project were positive across all the focus groups. Central themes identified were Feedback on the Project, Motivation to Exercise, Criticism of the NHS, Mental Wellbeing, Engagement in a Post Pandemic New Normal, Accessibility and Inclusivity, Empowerment and Building Social Capital.DiscussionThe focus groups evidenced that the project had broad impact. Participants expressed empowerment and ownership and described a range of social capital enrichment generated through the project including networks and friendships, access to the institutional resource of health science, and the opportunity to engage with a health and leisure activity that was valued and meaningful.

Divergent immune profiles in distinct populations - A vietnamese-german comparison

The human immune system exhibits fascinating diversity, sculpted by an intricate interplay of genetic and environmental influences. This study delves into these complexities by comparing the immunological landscapes of healthy individuals from distinct backgrounds: 40 Vietnamese and 24 German participants. Our comprehensive analysis, encompassing 42 lymphocyte populations and 17 cytokines, reveals profound differences in immune profiles between these two populations. Utilizing multicolor flow cytometry and advanced analytical platforms, we conducted a comprehensive characterization of the cellular and molecular components of individual immune systems. Statistical analyses revealed highly significant differences (p < 0.05) between Vietnamese and German cohorts in 33 out of 42 lymphocyte populations and 15 out of 17 cytokines. These disparities encompassed a wide range of immune cell subsets, including T, B and NK cells and involved both activating and inhibitory immune regulators. Healthy Vietnamese subjects exhibited significantly higher numbers of B, T and NK cells compared to their German counterparts. Vietnamese participants displayed higher proportions of plasma cells, immature B cells, and B cells with low CD21 expression (CD21low), which have a phenotypic characteristic of chronic stimulation. Of the 16 subpopulations of CD4+ and CD8+ T cell subpopulations, 11 were significantly elevated in Vietnamese compared to German subjects. Additionally, Vietnamese participants expressed higher proportions of markers for functional and activating NK receptors, indicating the presence of highly cytotoxic NK cells in this population. Almost all of the 17 cytokines examined were significantly lower in Vietnamese subjects. These results demonstrate statistically significant variations in immunological profiles between healthy individuals from Eastern and Western populations. Our findings suggest that caution should be exercised when applying Western reference health profiles to Eastern subjects in clinical settings. This comprehensive analysis underscores the importance of considering population-specific immune profiles in clinical and research contexts, particularly when evaluating immunological parameters across diverse ethnic groups.

Role preferences for ethnic autonomous region government in emergency management in China

China's ethnic autonomous regions, inhabited by diverse ethnic groups and located near national borders or at provincial intersections, confront complex natural, relatively underdeveloped economic, and ethnic harmony challenges. Governments balance central government-assigned tasks and ethnic harmony, showing varied responses: some prioritize stability, others focus on management, and some are indifferent to local emergencies. Given this phenomenon, why do governments in these regions vary in their responses to emergencies? This research, based on government role theory, examines how role preferences influence government behavior in emergency management, identifying two key roles: economic man and social man, and establishes a four-quadrant role analysis framework: : local guardian, political competitor, moral paragon, and indifferent bystander. Grounded theory explains these roles and evaluation indicators, with evaluations from 44 scholars gathered via questionnaire, and the indicator weights determined using the Analytic Hierarchy Process. The weight matrix then calculates economic man (X) and social man (Y) values for 272 cases based on expert scores. The research results reveal that (1) these governments exhibit an overall role preference of “local guardian > political competitor > indifferent bystander > moral paragon” in emergency management. (2) This ranking also reflects their preference for the economic man role. (3) Factors contributing to this ranking include cultural differences, administrative contracting, and performance tournaments within the Chinese system and administrative ethics. These findings provide theoretical insights into emergency management role preferences in multi-ethnic, multi-racial, and even multicultural regions, ultimately aiming to enhance local government emergency management efficiency, optimize policy formulation, and ensure community resilience.