Diverse Ethnic Groups Research Articles

Cross-cultural agenda in a theological institution: A review of St. Andrew’s Kabare, Kenya

This research article sets out to understand the extent to which a cross-cultural agenda of inclusivity and the appreciation for the ‘other’ (ubuntu) was addressed at St. Andrew’s College of Theology and Development, Kabare, Kenya, which has been viewed as a conglomeration of diverse ethnic groups, races, and nations. Despite her leadership’s acknowledgement of her rich cross-cultural diversity, as they celebrated 40 years’ of institutional existence, from 1977 to 2017, its execution was not spelled out explicitly. While appreciating the barriers of cross-cultural engagements as including, but not limited to: language, conflicting values, irrelevant studies and knowledge for diverse assemblages, geographical distance, ethnocentrism, bad-mouthing and character assassinations, and stereotypes, our main concern remains: what were the deliberate steps that were employed at St Andrew’s Kabare to promote a cross-cultural agenda? In its methodology, it employs hybridity in data gathering. That is, it utilised an in-depth interview (IDI), the use of key informant interviews (KIIs), the use of unpublished Church Synod reports, and a review of relevant literature in order to unveil the problem under consideration.Intradisciplinary and/or interdisciplinary implications: This research article contributes to the intradisciplinary and/or interdisciplinary implications by demonstrating how cross-cultural agenda is a matter whose interplay goes across the disciplines of theology, communication, culture, oral history and church history, among others.

Traditional medicine use to manage hypercholesterolemia, hyperglycaemia and hypertension in Ecuador

Abstract Background Although the use of traditional medicine (TM) to manage health issues is frequently reported, clinical guidelines often overlook this practice. This study aimed to describe the frequency of TM use to control 3 cardiometabolic risk factors for non-communicable diseases (arterial hypertension, hypercholesterolemia, and hyperglycaemia, collectively referred to as CMRF here); and associated sociodemographic, economic, and clinical characteristics. Methods Descriptive cross-sectional study with a representative population of two health districts in Ecuador, one urban in southern Quito and one in a forested rural area with diverse ethnic groups in Esmeraldas. We included 602 individuals with at least one CMRF and calculated the proportion of those who reported regular use of TM (herbal or traditional remedies) to control their CMRF. We used a multivariable logistic regression model to calculate Odds Ratios for TM use according to sociodemographic, economic, and clinical characteristics. Results TM was commonly used to control CMRF in both sociocultural contexts (39.4% Esmeraldas, 31.1% Quito), often in combination with conventional medicine (CM). A notable percentage of people (33.9% Esmeraldas, 39.0% Quito) did not take any treatment for their CMRF, and the rest used CM alone. In both settings, education was significantly associated with TM use. While in Quito people with higher education were more likely to use TM (aOR 2.04, 95%CI 1.03-3.90), in Esmeraldas, it was more common among people without formal schooling (aOR 3.76; 95%CI 1.59-8.88) as well as those of younger age (aOR per year 0.97; 95%CI 0.95-0.99) and from Afro-Ecudorian ethnicity (aOR 2.13; 95%CI 1.02-4.45). Conclusions Traditional medicine is used by a significant portion of Ecuador’s population, highlighting the need for a more accessible and intercultural approach to healthcare. Key messages • The use of traditional medicine to address hypertension, hypercholesterolemia, and hyperglycaemia appears to be widespread in different sociocultural and economic contexts of Ecuador. • To promote intercultural health, understanding the diverse sociocultural patterns associated with the use of traditional medicine, often combined with conventional medicine, is crucial.

Validity of the Multigroup Ethnic Identity Measure for Māori, Pacific, Asian & European adolescents

Abstract Background Ethnic identity is important for positive health and wellbeing outcomes, especially for Indigenous youth and adolescents from minoritised ethnic groups. The Multigroup Ethnic Identity Measure (MEIM) is widely used to examine ethnic identity as a general phenomenon across ethnic groups. However, evidence regarding its validity for adolescents from different ethnic backgrounds is mainly limited to the US context. This study investigated psychometric properties of the MEIM, for the first time, within a large ethnically diverse population-based sample in New Zealand. Methods We used data from the Growing Up in New Zealand study. Participants were 4500 12-year-olds and included 22.4% Māori (the Indigenous people of New Zealand), 16.7% Pacific, 14.8% Asian and 51.9% European young people. 45.7% were cisgender boy, 37.4% were cisgender girl, and 16.4% were non-binary, trans or unsure. We conducted factor analysis for the 12-item MEIM. Results Confirmatory factor analysis model fit tended to be best for a solution with two factors representing two ethnic identity subcomponents of Exploration and Affirmation/Belonging. A single ‘ethnic identity’ factor showed a slightly weaker model fit. Exploratory factor analysis revealed a 2-factor structure with a slightly different item composition as compared to the original MEIM subscales. The findings were largely comparable across ethnic groups. Conclusions The MEIM appears to be a valid measure for Māori, Pacific, Asian and European young people. However, nuances may exist due to unique contexts including structural factors, societal norms and challenges, opportunities and access to cultural engagement. Ethnic identity is strongly linked to health and wellbeing including quality of life, self-esteem and life satisfaction. Therefore, we recommend acknowledging nuances of ethnic identity during an important time of development within diverse cultural contexts, by applying subscales and subgroup analyses where possible. Key messages • The Multigroup Ethnic Identity Measure is valid and appropriate to use at age 12-years among diverse ethnic groups including Māori, Pacific, Asian and European. • Nuances of ethnic identity should be acknowledged as an important factor for health and wellbeing, especially during critical times of transition for adolescents within diverse cultural contexts.

Decomposition and Changes in InVivo Post-HA Filler Injection: A Review.

Hyaluronic acid (HA) fillers are widely used in aesthetic medicine, but their invivo behavior and long-term effects are not fully understood. To review the decomposition and changes occurring in the body following HA filler injections, focusing on crosslinking agents, degradation processes, and tissue responses. This review analyzed oxidative and enzymatic degradation processes of HA fillers, evaluated the impact of 1,4-Butanediol Diglycidyl Ether (BDDE) crosslinking, and examined histological changes post-injection. Uncrosslinked HA degrades rapidly due to endogenous hyaluronidase, while crosslinked HA undergoes slower degradation via free radicals and hyaluronidase. Complete cross-linking (C-MoD) showed better durability compared to partially cross-linked BDDE (P-MoD). The concept of modification efficiency (MoE) was proposed to optimize filler safety and viscoelastic properties. Histological analysis revealed collagen capsule formation and autologous tissue replacement, affecting long-term outcomes. The degree of chemical modification (MoD) influences filler durability and safety, with concerns raised about potential delayed immune reactions from accumulated pendent BDDE. Clinicians should consider injection site, tissue conditions, and filler properties for safe and effective HA filler use. Emphasizing thorough BDDE removal and optimal crosslinking can enhance treatment safety and efficacy. The balance between achieving desired viscoelastic properties and minimizing potential risks is crucial. Future studies should include diverse ethnic groups to validate findings and further explore long-term tissue responses to HA fillers.

Evaluating the reliability and validity of the Strengths and Difficulties Questionnaire in a heterogeneous ethnic young cohort from northeast India

Abstract Introduction: The strengths and difficulties questionnaire (SDQ) is extensively utilized to assess adolescent psychosocial problems. Despite its global use, the instrument’s reliability and validity across diverse ethnic populations remain under-examined. This study evaluates the reliability and validity of the SDQ among adolescents from an ethnic young cohort from Northeast India. Methodology: The present study followed a cross-sectional descriptive study design. The population for the study comprised children aged 13–17 years, studying in various government and public schools located in districts in Northeast India. In this study, a total sample size of 400 participants was selected. The SDQ was used. The researcher used the Statistical Package for the Social Sciences (SPSS) version 23 to analyze and measure the data. The study was undertaken with the approval of the scientific committee and ethical committee. Results: The internal consistency of the SDQ, as indicated by a Cronbach’s α of 0.846, suggests high reliability. Exploratory factor analysis identified five distinct factors from the SDQ items, with Bartlett’s Test of Sphericity and the Kaiser–Meyer–Olkin (KMO) measure confirming the appropriateness of factor analysis (χ² =1880, df = 276, P < 0.001; KMO = 0.848). Factors were deemed significant with loadings ≥0.3. Conclusion: The findings affirm the SDQ’s reliability and factor structure within this multiethnic context of Northeast India, underscoring its potential as a valid tool for screening psychosocial issues among diverse ethnic groups. This validation enhances the SDQ’s applicability for mental health assessments and interventions across varied Indian ethnicities.

Translating official documents: an art of governance by translation in the Qing dynasty

State governance is, in many ways, a discursive practice that relies on the creation, translation, and transmission of governance-oriented texts. The act of governance by translation typically occurs in multi-ethnic, multilingual, and unified political contexts. When translation adheres to established patterns and effective regimes, it forms a governance technique known as “translation governmentality.” In the Qing dynasty (1644–1911), confronted with the challenge of governing a vast territory with diverse ethnic groups speaking different languages, the Qing authorities prioritized the translation of official documents to implement this translation governmentality. Despite its significance, a comprehensive overview of official document translation in the Qing dynasty within the framework of governance by translation has not received sufficient attention. This study employs documentary analysis to understand the historical contexts of official document translations, interpret the motivations behind these translations, and reconstruct the organized regimes of translation practices in the Qing period. The findings reveal that the Qing dynasty developed a relatively organized and mature translation regime for official documents by establishing translation agencies, appointing specialized translation officials, and adopting multilingual translation modes. This governance-oriented translation regime effectively shaped the core concepts, institutional systems, and organizational mechanisms of state governance in the Qing dynasty. Additionally, it contributed to establishing the legitimacy of state governance during that era.

Culture and ICD-11 personality disorder: Implications for clinical practice across diverse ethnic groups.

Personality disorder (PD) in ICD-11 is defined primarily by self and interpersonal dysfunction and optionally by other qualifiers. This definition is inseparable from relativism of cultural determinants. This review aimed to synthesize the relevant aspects of the influence of culture on clinical practice and health management for this condition, aligning them to the ICD-11 PD model. In Scopus, we systematically searched for studies that included the text strings: cultur* | personality AND (disorder* OR patholog*) without any restrictions on publication date or language or other exclusion criteria, up to November 2022. Evidence suggests that cultural variables in ethnic groups (Western and non-Western) such as the individualist/collectivist philosophy, historical/generational trauma, immigration, acculturation, religion, and gender influence the etiology, semiology, epidemiology, evaluation, diagnosis, treatment, and management of health services for ICD-11 PD. We discuss the limitations and propose future lines of research on this topic based on our knowledge and experience. In this review, we provide the scientific community and clinicians with relevant cultural information to guide their practice and propose strategies to manage PD from the ICD-11 model. More research is needed using mixed study methodologies on stigma, the experiences of patients, clinicians, and health agencies, to reduce the care gaps and achieve a culturally comprehensive, inclusive, and competent use of this new model.

Understanding the Socio-economic and Political Ramifications of the 2021 Military Coup on the Communities in the Indo-Myanmar Borderlands

Myanmar has experienced two major military coups since its independence in 1948. These coups have had a significant impact on the socio-economic and political landscape of the country, particularly in the Indo-Myanmar border region. The region, which shares a 1,643-km-long border with India, is home to diverse ethnic groups with distinct cultures and languages. Military coups have not only disrupted the lives of these communities but have also perpetuated long-standing conflicts in the region. This article aims to unravel and scrutinise the ramifications, shedding light on the intricacies of socio-economic disparities, political destabilisation and the erosion of fundamental rights and freedoms by elucidating the complex interplay between military rule, socio-economic inequalities and political dynamics and the far-reaching implications of the 2021 military coup in the Indo-Myanmar borderland. The article employs a qualitative research methodology, drawing on primary and secondary sources, to provide a comprehensive analysis of the impact of military coups on the Indo-Myanmar border region.

Predictive validity of the Psychopathy Checklist: Screening Version (PCL:SV) in a sample of New Zealand Māori and European male prisoners.

Numerous studies have investigated the predictive validity of the Hare Psychopathy Checklist (PCL), but the majority have used samples from North America. The PCL may inform important decisions about people's futures; recognition has been growing of the importance of ensuring that its psychometric properties are established in each jurisdiction where it is used, especially for Indigenous and non-European populations. The present study examined the predictive properties of the Hare Psychopathy Checklist: Screening Version (PCL:SV; Hart et al., 1995) in 371 New Zealand (NZ) male prisoners, including NZ European and NZ Māori subsamples. Discrimination analyses showed that PCL:SV total scores had moderate predictive accuracy for any new conviction within 5 years of release; no significant differences were detected for Māori versus NZ European on this outcome. PCL:SV Factor 2 (Lifestyle/Antisocial) scores were moderately predictive of violent recidivism within 5 years of release. In a second, independent sample of male prisoners (n = 102), both PCL:SV total and Factor 2 scores showed moderate predictive accuracy for serious institutional violence. Additionally, PCL:SV Facets 1 (Interpersonal) and 2 (Affective) scores were uniquely associated with time to sexual and violent recidivism, respectively. Understanding the predictive performance of clinical risk measures across diverse ethnic groups is an important step toward identifying and addressing ethnic disparities in criminal justice outcomes. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Prevalence and factors associated with the use of traditional medicine in individuals with hypercholesterolemia, hyperglycaemia, and arterial hypertension in Ecuador: results from a population-based study in two health districts.

While traditional medicine (TM) is employed by a significant portion of the global population for managing health issues, clinical guidelines and state recommendations often overlook this practice. The aim of this study was to describe the frequency of use of TM to control 3 metabolic risk factors (MRF): hypertension, hypercholesterolemia, and hyperglycaemia; and the sociodemographic, economic, and clinical characteristics associated with the use of TM. Cross-sectional descriptive study that analyses data obtained from a representative population survey in 2 health districts, one urban in the south of Quito and another in a forested rural area with diverse ethnic groups in Esmeraldas, Ecuador. We include 602 individuals with at least one MRF. We calculated the proportion of people reporting the regular use of TM (herbal or traditional remedy) to control their MRF and we assessed potential associations with sociodemographic, economic, and clinical characteristics with a multivariable logistic regression model. In two very different sociocultural contexts in Ecuador we found that use of TM to control MRF was frequent (39.4% in Esmeraldas, 31.1% in Quito), frequently in combination with CM. There is a notable percentage of people, 33.9% in Esmeraldas and 39.0% in Quito, who did not take any treatment for their MRF, and the remainder used CM alone. In both settings, an individual's education lever was significantly associated with TM use. Whereas in Quito individuals with higher education more frequently treated their MRF with TM (aOR 2.04, 95% CI 1.03-3.90), in the rural, hard-to-reach context of Esmeraldas, it was more frequent among people with no formal schooling (aOR: 3.76; 95%CI 1.59-8.88), as well as those of younger age (aOR by year: 0.97; 95% CI 0.95-0.99) and afro ethnicity (aOR: 2.13; 95%CI 1.02-4.45). Traditional medicine is used by a significant proportion of the population in Ecuador, highlighting the need for a more accessible and intercultural healthcare approach. The health system should ensure access to the necessary information and resources for the management of their metabolic risk factors.

A strategy of Q-markers identification based on effect, property flavour material basis and rapid quantitative evaluation via near-infrared spectroscopy and chemometric methods for the quality control of Flos Trollii (FT)

Ethnopharmacological relevanceFlos Trollii (FT) is the dried flower of Trollius Chinensis Bunge of Ranunculaceae with the pharmacological properties of anti-inflammatory, antibacterial, antiviral, anti-oxidative. The herb FT is not only a traditional Chinese medicine (TCM) but also an extensively utilized ethnic medicine, employed by diverse ethnic groups including Mongolian, Tibetan, and Kazakh. Aim of studyFT was taken as an example to construct a strategy of quality markers (Q-markers) identification based on effect, property flavor material basis, and rapid quantitative evaluation using near-infrared (NIR) spectroscopy and chemometric methods of TCM. Materials and methodsInitially, the anti-inflammatory efficacy of FT from three places of origin was evaluated using the RAW264.7-cell inflammatory model, and the bitter property flavor was characterized using an electronic tongue. The high-performance liquid chromatography(HPLC) fingerprint of FT was generated, and the quality of FT from different origins was evaluated employing chemometrics. Next, potential anti-inflammatory and bitter property flavor compounds were screened utilizing a fingerprinting-effect relationship and fingerprinting-property flavor relationship model using partial least squares regression (PLSR). The Q-markers of the FT were confirmed based on the testability principle. Then, a swift, uncomplicated, and precise Q-marker content of the FT prediction model was developed by adopting NIR. ResultsThe main common fingerprinting peaks affecting FT's efficacy and property flavor were screened. Five of these compounds, 2″-O-beta-L-galactopyranosylorientin, orientin, vitexin, veratric acid, and isoquercitrin, characterized using HPLC and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS), could be regarded as Q-markers of FT. Q-marker content of the FT prediction model developed adopting NIR spectroscopy was rapid and effective. ConclusionAccording to the strategy proposed in this study, a quantitative NIR spectroscopic method to identify Q-markers could be a tool to improve the QC efficiency of TCM.

HLA Genetic Variants in COVID-19 Susceptibility: Assessing Diversity in Indian and Global Populations

Background: The rapid spread of the SARS-CoV-2 virus has had a global impact on various ethnic groups. In order to assess the genetic predisposition of the Indian population towards COVID-19, a comparative analysis was conducted using the Human Leukocyte Antigen (HLA) to investigate the frequencies of polymorphisms directly or potentially associated with COVID-19 susceptibility, severity, immune response, and fatal outcomes in comparison to other major populations. Objectives: The objective of this study is to evaluate the genetic predisposition of the Indian population to COVID-19 by analyzing the frequencies and associations of Human Leukocyte Antigen (HLA) polymorphisms. In addition, by delineating the role of specific HLA variants in the Indian context, the study seeks to enhance our understanding of genetic factors influencing COVID-19 impact and contribute to personalized approaches for disease management and prevention across diverse ethnic groups. Methods: We collected allelic information for DRB1 gene from 653 populations globally, as documented in The Allele Frequency Net Database (AFND). Data on COVID-19 susceptibility, severity, mortality, and protective factors were obtained from a previous global study. This study aimed to compare the specific frequencies of HLA-DRB1* in different ethnic groups, including other Indian populations with COVID-19-associated alleles and protective factors. Results: HLA-DRB1*01 was identified as a significant determinant of COVID-19 susceptibility among patients in 28 states of Mexico, whereas DRB1*08 in Saudi Arabian populations, DRB1*09:01 in Japanese populations, and DRB1*15:01 in Italian populations also showed this association. Likewise, DRB1*04 in the Iranian population played a role in disease severity, and DRB1*08 in the Italian population was associated with mortality in COVID-19 patients. In addition, alleles DRB1*01:01 and DRB1*04:01 were found to exhibit a protective role in Northeast England, whereas DRB1*04 demonstrated protective effects in Saudi Arabian populations. Conclusion: The involvement of HLA in COVID-19 requires further investigation, and epidemiological studies should focus on HLA profiles as determinants of the host immune system. Prolonged homozygosity in particular genomic regions could potentially increase susceptibility to COVID-19 infection. Therefore, prudent management strategies are recommended for this pandemic in isolated communities in India and worldwide.

Improving the patient experience of transition from hospital to home after stroke: a service evaluation

The period when a patient returns home from hospital after a stroke can be a challenging time. There is often a need for patients to be discharged quickly; therefore, a poor discharge experience for patients and their carers is consistently reported. Individuals can feel anxious and unsupported during this period. The aim was to conduct a service evaluation and improvement project in a regional stroke service to explore the experiences of patients being discharged home from the Acute Stroke Unit with support from the Early Supported Discharge Service. Specific elements of a previously validated questionnaire were completed by nine participants. The service evaluation built on previous research and expanded the data by including patients with communication or cognitive difficulties. Patients generally had a positive experience of discharge home from hospital. Most patients received the information they needed and felt involved in discharge decisions. However, one-third of patients experienced a delay related to waiting for medication. The need for psychological support was identified. A collaborative approach involving patients and professionals is suggested to create changes in stroke services. Patients should be offered psychological support and medication delays should be addressed. Any subsequent study would be improved by recruiting a larger number of participants, particularly from more diverse ethnic groups, and offering the option of online or hard copy questionnaire distribution.

Traditional sacred meanings in the ethnoregional culture of Altai

This article presents the study of methodological approaches to the study of the traditional sacred ethnoregional culture of Altai. The essence of the concept of "sacred" culture is considered. The theoretical aspects of the study of the "sacred" ethnoregional culture of Altai are revealed. A comparative analysis of various traditional forms of sacredness in the development of the ethnoregional culture of Altai is carried out. The problem of preserving the cultural heritage of Altai is considered.The purpose of the study is to reveal the features of traditional sacred meanings in the ethnoregional culture of Altai. Objectives: - to consider the theoretical aspects of the study of the sacred ethnoregional culture of Altai; - to conduct a comparative analysis of various traditional forms of sacredness in the development of the ethnoregional culture of Altai. The subject of the study is the traditional sacred meanings in the ethnoregional culture of Altai.The object of the study is the ethnoregional culture of Altai. The practical significance of this work lies in the possibility of using the data obtained in the creation of local regional programs for the preservation of ethnocultural traditionalism. The method and methodology of the work: the basis of the research is the principle of a systematic approach. To study methodological approaches to research, the sources of information were textbooks and monographs by such authors as M. Eliade, T.V. Bernyukevich, I.Ya. Murzina, N.I. Kaplan, G.M. Kazakova, V.A. Lipinskaya and others. Based on this study, it can be concluded that the culture of Altai is a huge layer of ethnographically diverse ethnic groups. Each ethnic group has its own sacred values and social patterns through which these values can be passed on to subsequent generations. This can be traced by the example of the Altai house painting, in everyday objects there is a complex semantic complex of sacralization. On the one hand, painting appears as a way of sacralizing human existence, on the other hand, it is a channel for transmitting appropriate social patterns that influence the consolidation of bearers of a particular culture. The boundaries of the sacred here are determined by the substantial meanings of human existence and the civilizational level of development of the sacralization of values. Traditional sacred meanings are intertwined with the way of life, culture and way of life of the people.

Rare genetic variants of NLRP12 in Admixed Latino-American Children with SARS-CoV-2-related Multisystem Inflammatory Syndrome.

Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare, potentially fatal complication of SARS-CoV-2 infection. Genetic defects in inflammation-related pathways have been linked to MIS-C, but additional research is needed, especially in diverse ethnic groups. The present study aimed to identify genetic variants underlying MIS-C in Brazilian patients. Whole-exome sequencing was performed, focusing on genes involved in the host immune response to SARS-CoV-2. Functional assays assessed the impact of selected variants on NF-κB signaling. Nine rare, potentially deleterious variants were found in eight of 21 patients, located in IL17RC, IFNA10, or NLRP12 genes. Unlike the wild-type NLRP12 protein, which inhibits NF-κB activation in HEK 293T cells, the mutant NLRP12 proteins have significantly reduced inhibitory properties. In conclusion, our results indicate that rare autosomal variants in immune-related genes may underlie MIS-C, highlighting the potential role of NLRP12 in its predisposition. These findings provide new insights for the appropriate management of MIS-C.

Using Ontology to Analyze English Comments on Social Networks

Chatbots have become interesting for many users as technology becomes more and more advanced. The need for information exchange among people through computer systems is increasing daily, raising the preference for using chatbots in most countries. Since Vietnam is such a developing country with a variety of ethnic groups, it requires much attention to the proliferation of social networks and the expansion of the cooperative economy. Regarding social networks, the inappropriate use of words in everyday life has become a significant issue. There are mixed reviews of praise and criticism on social networks; and we try to reduce the negative language use and improve the quality of using social networks language. We aim to meet users’ needs on social networks, promote economic development, and address social issues more effectively. To achieve these goals, in this paper we propose a deep learning technique using ontology knowledge mining to collect and process comments on social networks. This approach aims to enhance the user experience and facilitate the exchange of information among people by mining opinions in comments. Experimental results demonstrate that our method outperforms the conventional approach.

Ethnic sensitivity analyses of pharmacokinetics, efficacy and safety in polycythemia vera treatment with ropeginterferon alfa-2b.

Ropeginterferon alfa-2b (Ropeg) is approved for the treatment of adults with polycythemia vera (PV). This report aims to analyze the ethnic sensitivity of Ropeg for the treatment of PV, comparing the pharmacokinetics (PK), efficacy, and safety profiles across diverse ethnic groups. We conducted a relevant review of PV and analysis of data obtained from clinical studies involving Ropeg. The PK behavior of ropeg showed no significant differences between Chinese and overseas populations. Their efficacy and safety profiles were similar across the ethnic groups. The analyses indicated that the dose-exposure-response profile of Ropeg was consistent irrespective of ethnic variations. The results suggest that Ropeg exhibits a consistent PK and pharmacodynamics profile and a similar therapeutic effect across different ethnic groups, confirming its efficacy and safety in the global treatment of PV. More generally, these findings support the broader application of Ropeg in diverse patient populations and emphasize the need for an inclusive clinical practice.

WASOG 2023 conference highlights.

The World Association of Sarcoidosis and Other Granulomatous Diseases (WASOG) 2023 conference held in Stockholm, Sweden, focused on disseminating the science and updating the interstitial lung diseases (ILDs) community with the latest science and concepts in precision medicine. This article summarizes the first four sessions of the conference that focused on disease and phenotype characterization, genetics in population cohorts, uses of biobanks and big data, epidemiology in diverse racial and ethnic groups, and data-driven applications that can be applicable to move the ILD field toward precision medicine.

Abstract A108: Movement Over Virtual Reality (MOVR)-Latinx: Exploring the Acceptability and Feasibility of a Novel Virtual Reality Latin Dance Intervention among Latinos/as to Promote Physical Activity

Abstract Introduction: Physical inactivity is a significant public health concern contributing to numerous chronic diseases including cancer. Latina/o/x adults have higher rates of sedentary behavior compared to other racial/ethnic groups in the United States. Despite evidence supporting the efficacy and growing adoption of VR exercise programs, little is known about the role they play in the Latina/o/x community. The purpose of this study is to assess the acceptability and feasibility of a culturally tailored Latin dance inspired Virtual Reality (VR) intervention to promote physical activity and reduce cancer risk factors among Latina/o/x adults in Los Angeles. Methods: We used a community based participatory research approach to conduct two focus groups (n = 24) with diverse participants who self-identified as Latina/o/x and had not previously participated in a VR activity to explore acceptability and feasibility of a future culturally tailored VR study to promote physical activity in the Latina/o/x community. Participants were paired with culturally and language congruent student guides who provided 1:1 instruction and a 30-minute introductory session. The VR session was followed by in-person focus groups and baseline surveys that included demographic questions. Participants received a $100 gift card for their participation. Results: All participants were Spanish-speaking (n = 23, 95%) Latinos born outside the U.S. and the majority were Mexican (n = 9; 37.5%), the average age was 45 (range = 26 - 71), more than half had a high school education or higher (n = 13; 54.2%), and many were married or living with a partner (n = 15; 62.5%). Preliminary themes included: VR to promote intergenerational connections, the use or VR to overcome physical or environmental barriers, acceptability of VR as a therapeutic intervention, stress reduction via VR engagement, and the need for cultural tailoring to promote VR engagement. Conclusion: The majority of our sample of Latina/o/x participants reported VR as an acceptable means to engage in physical activity. Exploring ways to engage diverse racial and ethnic groups in research through community based participatory research and leveraging technology to build culturally informed interventions is an innovate approach to address cancer disparities. The information gained from this study will provide valuable insights into the acceptability and feasibility of a future randomized controlled trial. Citation Format: Desiree R. Acosta, Vanessa N Torres, Gael Perez, Jailene Cruz, Liana Gutierrez, Josyel Castellon, Paulina Monteon-Garcia, Yelba Castellon-Lopez. Movement Over Virtual Reality (MOVR)-Latinx: Exploring the Acceptability and Feasibility of a Novel Virtual Reality Latin Dance Intervention among Latinos/as to Promote Physical Activity [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A108.

Факторы, осуществляющие обеспечение этнополитической безопасности России

The presented scientific work focuses on examining a number of key factors that can significantly impact the provision of ethnopolitical security in Russia. This study raises several issues regarding the current state of ethnopolitical security in the country, as well as the role and place of technological progress, which exerts a substantial influence on modern society, including the sphere of ensuring the country’s ethnopolitical security. In the context of Russia, this issue becomes particularly relevant given its multinational composition and the diversity of ethnic groups. The introduction of innovative approaches and technologies to address the challenges of ensuring ethnopolitical security in Russia may contribute to more effective management of interethnic conflicts, prevention of tensions, and the maintenance of stability within the country. Ethnopolitical security is one of the key components of national security, since ethnic conflicts and contradictions can destabilize the political system and lead to social upheavals. In the context of a multinational state, such as Russia, ensuring ethnopolitical security becomes a matter of paramount importance, requiring in-depth scientific analysis and the development of effective strategies.