The analysis of data and publications concerning the activities of the sanitary and epidemiological service (SES) during The World War II has been made in the memory of the 75th anniversary of the historical Victory of the Soviet people in the Great Patriotic War. An expert and analytical study was performed. There was a report of the work of the state sanitary Inspection and Sanitary-epidemiological station of the Kirovsky district of Moscow in 1944. The effort of the sanitary service of the Kirovsky district in 1944 allowed performing the supervision on controlled objects by 162.3% and restored the house water pipes and sewers which were destroyed in the past winter; to improve the housing stock of the district; to renovate and provide equipment of the hostel, to improve the content of dormitories and eliminate lice, to open 4 new kindergartens and nursery toddlers ‘ groups and to improve the sanitary condition and maintenance of children’s institutions, to organize the summer improving children’s company, to repair schools, to improve nutrition in child care, to improve health of workers and the maintenance of industrial and municipal enterprises, to reduce the incidence of injuries at the leading industrial enterprises, to improve the working conditions of Junior enterprises, to reduce the number of occupational diseases and occupational injuries; to reduce the incidence of influenza, dysentery, diphtheria and malaria, to exceed the preventive vaccination plan ahead of time, to achieve almost complete (98.3%) hospitalization of epidemic patients, to organize connections with public health instructors, to exceed the work plans of all SES laboratories, to perform scientific and practical work. Conclusion. The work of the state sanitary Inspection and sanitary inspection Service of the Kirovsky district of Moscow in 1944 provided an appropriate level of sanitary conditions at enterprises, institutions and the territory of the district. Military difficulties and limited human resources did not affect on the use of the main forms of work of the service: preventive and routine sanitary supervision, laboratory and instrumental research methods, vaccination, public health education, and administrative measures.