Distraction Test Research Articles

CSM 2014 Orthopaedic Section Poster Presentations (OPO1106–OPO1165, OPO2218–OPO2298, OPO3106–OPO3183)

CSM 2014 Orthopaedic Section Poster Presentations (OPO1106–OPO1165, OPO2218–OPO2298, OPO3106–OPO3183)

Quantitative investigation of ligament strains during physical tests for sacroiliac joint pain using finite element analysis

It may be assumed that the stability is affected when some ligaments are injured or loosened, and this joint instability causes sacroiliac joint pain. Several physical examinations have been used to diagnose sacroiliac pain and to isolate the source of the pain. However, more quantitative and objective information may be necessary to identify unstable or injured ligaments during these tests due to the lack of understanding of the quantitative relationship between the physical tests and the biomechanical parameters that may be related to pains in the sacroiliac joint and the surrounding ligaments. In this study, a three-dimensional finite element model of the sacroiliac joint was developed and the biomechanical conditions for six typical physical tests such as the compression test, distraction test, sacral apex pressure test, thigh thrust test, Patrick's test, and Gaenslen's test were modelled. The sacroiliac joint contact pressure and ligament strain were investigated for each test. The values of contact pressure and the combination of most highly strained ligaments differed markedly among the tests. Therefore, these findings in combination with the physical tests would be helpful to identify the pain source and to understand the pain mechanism. Moreover, the technology provided in this study might be a useful tool to evaluate the physical tests, to improve the present test protocols, or to develop a new physical test protocol.

Distraction test of the posterior superior iliac spine (PSIS) in the diagnosis of sacroiliac joint arthropathy

BackgroundThe sacroiliac joint (SIJ) is a frequently underestimated cause of lower back (LBP). A simple clinical test of sufficient validity would be desirable. The aim of this study was to evaluate the diagnostic value of a new PSIS distraction test for the clinical detection of SIJ arthropathy and to compare it to several commonly used clinical tests.MethodsConsecutive patients, where a SIJ pathology had been confirmed by an SIJ infiltration were enrolled (case group, 61 SIJs in 46 patients). Before infiltration, patients were tested for pain with PSIS distraction by a punctual force on the PSIS in medial-to-lateral direction (PSIS distraction test), pain with pelvic compression, pelvic distraction, Gaenslen test, Thigh Thrust, and Faber (or Patrick’s) test. In addition, these clinical tests were applied to both SIJs of a population of individuals without history of LBP (control group, 64 SIJs in 32 patients).ResultsWithin the investigated cohort, the PSIS distraction test showed a sensitivity of 100% and a specificity of 89% for SIJ pathology. The accuracy of the test was 94%, the positive predictive value (PPV) was 90% and the negative predictive value (NPV) was 100%. Pelvic compression, pelvic distraction, Gaenslen test, Thigh Thrust, and Faber test were associated with a good specificity (> 90%) but a poor sensitivity (< 35%).ConclusionsWithin our population of patients with confirmed SIJ arthropathy the PSIS distraction test was found to be of high sensitivity, specificity and accuracy. In contrast, common clinical tests showed a poor sensitivity. The PSIS distraction test seems to be an easy-to-perform and clinically valuable test for SIJ arthropathy.

The effectiveness of simultaneous medial spindle and/or lateral tarsal strip procedure in East Asian patients who need endonasal dacryocystorhinostomy

To evaluate the effectiveness of simultaneous medial spindle procedure (MS) and/or lateral tarsal strip procedure (TS) with an endonasal dacryocystorhinostomy (DCR) for treatment of involutional medial punctal ectropion, horizontal eyelid laxity, and nasolacrimal duct obstruction. We conducted a retrospective, interventional study of DCR performed from March 2009 to July 2011 by a single surgeon (Baek SH). Patient age, sex, results of medial and lateral distraction test, surgical procedure, time of tube removal, duration of follow-up, functional and anatomical success rate, and causes of failed surgeries were recorded. Lateral lower eyelid laxity was evaluated by a medial distraction test, and medial lid laxity was evaluated by a lateral distraction test. A total of 241 eyes in 175 patients were included in this study. The proportion of combined surgeries to total DCR was 24.5% (59 of 241 eyes). DCR and MS (D + M) were performed on 23 eyes in 17 patients (9.5%) and DCR and TS (D + T) on 29 eyes in 17 patients (12.0%). Concurrent DCR, MS and TS (D + M + T) were performed on seven eyes in four patients (2.9%). Mean age was significantly higher in the combined surgery groups (63.8 ± 10.0 years) than in the DCR group (56.2 ± 10.6 years; p = 0.01, by Mann-Whitney U test). The anatomical success rates were 84.2% in D, 86.9% in D + M, 89.5% in D + T, and 85.7% in D + M + T (p = 0.61 by Kruskal-Wallis test). Functional success rates were 82.4% in D, 86.9% in D + M, 86.2% in D + T, and 85.7% in D + M + T (p = 0.91 by Kruskal-Wallis test). MS and TS performed concurrently with a DCR may be an effective tool to deal with epiphora due to complex clinical situations such as nasolacrimal duct obstruction, lid laxity, and involutional medial ectropion. It is recommended to examine punctum and lid laxity carefully using slit-lamp biomicroscopy and lid distraction test in patients with epiphora, especially in elderly patients.

The Effectiveness of a Simultaneous Medial Spindle Procedure for Involutional Punctal Ectropion With Lid Laxity in Patients Who Require Endonasal Dacryocystorhinostomy Instead of External Dacryocystorhinostomy to Prevent Pump Failure

The aim of this study was to determine the effectiveness of a concurrent medial spindle procedure (MS) to address involutional punctal ectropion and the proportion of combined surgery in patients who need endonasal dacryocystorhinostomy (DCR) instead of external dacryocystorhinostomy to prevent pump failure. We conducted a retrospective, interventional study on endonasal DCR and MS procedures performed between March 2004 and January 2009 by a single surgeon (S.H.B.). Patient age, sex, the results of a medial distraction test, the surgical procedure, follow-up duration, and cause of failed surgery were recorded. The indication for the medial spindle procedure was punctal eversion on slit lamp biomicroscopic examination with classifications of grades 2 and 3 on the medial distraction test. Endonasal DCRs were performed on 169 eyes in 121 patients, and DCR and MS (D + M) were performed on 23 eyes in 17 patients. The proportion of combined surgery to total DCR was 13.6%. Our primary success rate was 86.9% in the combined surgery group and 87.2% in the DCR group (P = 0.39). The MS for correction of punctal ectropion concurrently performed with endonasal DCR will be an effective tool to manage epiphora caused by complex situations, such as nasolacrimal duct obstruction and involutional punctal ectropion. We recommend careful examination of the punctum, which is invisible in normal conditions, under slit lamp biomicroscopy before endonasal DCR.

The Effectiveness of Simultaneous Lateral Tarsal Strip With Endonasal Dacryocystorhinostomy for the Treatment of Nasolacrimal Duct Obstruction and Lower Lid Laxity

The aim of this study was to evaluate the effectiveness of simultaneous lateral tarsal strip procedure (LTS) and endonasal dacryocystorhinostomy (DCR) for the treatment of nasolacrimal duct obstruction and lower lid laxity. We conducted a retrospective, interventional study of concurrent DCR with LTS for patients with nasolacrimal duct obstruction and lower lid laxity performed between March 2009 and July 2011 by a single surgeon (S.H.B.). Patient age, sex, the results of dacryoscintigraphy, time of tube removal, follow-up duration, and cause of failed surgery were recorded. Lower eyelid laxity was evaluated by a medial distraction test. A total of 29 eyes in 17 patients were included in the study. The mean age was 61.1 ± 11.8 years (range 41 to 81 years). The mean degree of lower lid laxity was 2.4 ± 0.5. Dacryoscintigraphy showed presac delay in 22 eyes (75.9%). The tube was removed after 11.3 ± 1.9 weeks. The primary anatomical success rate was 89.5% (27 eyes) and the functional success rate was 86.2% (25 eyes). Membranous obstructions were the cause of failed surgery in 2 patients, but both patients remained symptom free after revision surgery with a diode laser. Concurrently performed DCR with LTS can be an effective tool for the treatment of nasolacrimal duct obstruction and lower lid laxity. It is recommended for examining lid laxity carefully using lid distraction test in patients with epiphora.

Monoaxial Pedicle Screws Are Superior to Polyaxial Pedicle Screws and the Two Pin External Fixator for Subcutaneous Anterior Pelvic Fixation in a Biomechanical Analysis

Purpose. Comparison of monoaxial and polyaxial screws with the use of subcutaneous anterior pelvic fixation. Methods. Four different groups each having 5 constructs were tested in distraction within the elastic range. Once that was completed, 3 components were tested in torsion within the elastic range, 2 to torsional failure and 3 in distraction until failure. Results. The pedicle screw systems showed higher stiffness (4.008 ± 0.113 Nmm monoaxial, 3.638 ± 0.108 Nmm Click-x; 3.634 ± 0.147 Nmm Pangea) than the exfix system (2.882 ± 0.054 Nmm) in distraction. In failure testing, monoaxial pedicle screw system was stronger (360 N) than exfixes (160 N) and polyaxial devices which failed if distracted greater than 4 cm (157 N Click-x or 138 N Pangea). The exfix had higher peak torque and torsional stiffness than all pedicle systems. In torsion, the yield strengths were the same for all constructs. Conclusion. The infix device constructed with polyaxial or monoaxial pedicle screws is stiffer than the 2 pin external fixator in distraction testing. In extreme cases, the use of reinforcement or monoaxial systems which do not fail even at 360 N is a better option. In torsional testing, the 2 pin external fixator is stiffer than the pedicle screw systems.

Effects of combination pharmacotherapy and social skills training for schizophrenia: A randomized controlled trial

Pharmaco-psychosocial treatment (PPST) refers to a treatment paradigm combining pharmacotherapy with psychosocial therapy. We conducted an 18-month randomized controlled tracking study to evaluate the efficacy of social skills training (SST) in 11 individuals with schizophrenia on risperidone monotherapy. They were randomized to either SST or non-SST group, and Global Assessment Functioning (GAF) and Brief Psychiatric Rating Scale (BPRS) scores in the 2 groups showed gradual improvement. In the SST group, Digit Span Distraction Test (DSDT) at 12 and 18 months showed significant improvement. The Subjective Deficit Syndrome Scale (SDSS) scores in the SST group showed significant improvement after 6 months and showed a significant difference in comparison between the groups. After the subjective feeling of health was recovered, the items of motivation were recovered as a direct effect of SST. Some items of the Life Assessment Scale for the Mentally Ill (LASMI) score showed significant improvement (or significant trend) in only the SST group after 6 months. Items of daily life, work skills, and self-recognition were continuously improved. We report 2 cases in the SST group that had DSDT improvement in parallel with change of action and communication as a change of social function. This study is only exploratory due to the small number of cases. However, we have demonstrated potential improvement in cognitive function due to learning experiences that required working memory and attention, thus providing improvement in social life.

Is Traditional Lower Blepharoplasty a Superior Technique?

Sir:FigureWe read with interest the article entitled “Traditional Lower Blepharoplasty: Is Additional Support Necessary? A 30-Year Review” by Maffi et al. (Plast Reconstr Surg. 2011;128:265–273). This article describes the senior author's experience with traditional blepharoplasty and concludes that external incision with fat removal has a low complication rate and that routine support procedures are unnecessary. We have used both the traditional lower blepharoplasty and the fat-preserving technique1 for over 30 years and have only used the latter for the past 20 years. This technique consists of reducing the fatty hernia and approximating the capsulopalpebral fascia to the arcus marginalis1–5 (Fig. 1). Prospective studies comparing the “traditional” method with the “fat-preserving” method show that hernia repair is simple, safe, and reproducible, with very low morbidity and superior long-term results2,5 (Table 1).Fig. 1: (Above) Intraoperative photograph of fat hernia before reduction and capsulopalpebral hernia repair. (Below) The fat hernia is shown after reduction and repair by approximating the capsulopalpebral fascia to the arcus marginalis with interrupted 5-0 absorbable monofilament sutures.Table 1: Preoperative Tests Recommended for Selecting Patients for “Tightening/Anchoring” Procedures*Although we agree with Maffi et al. that a tightening procedure is not indicated when the eyelid tone is “adequate,” we disagree with their concept of concomitant “canthopexy” when the preoperative distraction test is “less than 6 mm” and “canthoplasty” when it measures more. We have found that both the values that reflect the muscle tone (snap-back test) and the degree of stretching of the canthal ligaments (distraction test) are necessary in selecting patients for lower lid support procedures and that over 80 percent of our patients qualify for such an intervention in contrast to their very small percentage. We define “adequate/normal tone” when the snap-back test and the distraction test are less than 1 second or less than 2 mm, respectively. In “mild” and in the majority of “moderate” and “severe” cases, we perform a tightening/anchoring procedure we call musculoplasty, as shown in Figure 2. Only in a small percentage of moderate and severe cases (<5 percent) do we perform other procedures in addition to musculoplasty. Musculoplasty consists of a single stitch of 5-0 absorbable monofilament that approximates the lower lid's orbicularis muscles to the dense fibrous tissue of the lateral orbital rim. No soft-tissue dissection and no undermining is performed in the lateral canthal region, and chemosis is typically either minimal (<5 percent of patients) or absent and, when present, subsides within 7 to 14 days without the use of steroid preparations. We have observed that chemosis is absent when the lateral canthal area is not invaded, and we attribute postoperative chemosis to surgical trauma to this region and not to lower blepharoplasty per se because in our experience chemosis is absent in these instances.Fig. 2: Musculoplasty consists of approximating the pretarsal and preseptal orbicularis to the dense fibrous tissue of the lateral canthal region.Finally, we disagree with Maffi et al. that the “traditional” approach of fat removal is easier to teach. We have found that surgeons in training who have been exposed to the basic principles of hernia repair in general surgery understand and learn readily the principles of hernia repair in the lower eyelids and are impressed by its simplicity2,5 (Fig. 1). In addition, the procedure requires less sedation, and no intraorbital bleeding/blindness has ever been reported because fatty tissue is not injected or manipulated.1–5 Fereydoun Don Parsa, M.D. Daniel Murariu, M.D., M.P.H. Alan Ali Parsa, M.D. Michael Cyrus Siah, B.A. Jennifer Armstrong, B.A. John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii DISCLOSURE The authors have no financial interest to declare in relation to the content of this communication.

The anterior shear and distraction tests for craniocervical instability. An evaluation using magnetic resonance imaging

Screening for integrity of the ligaments of the craniocervical complex has been suggested prior to the application of manual techniques to the upper cervical spine. However, most tests proposed lack validation limiting their usefulness clinically. This study examined the effect of the anterior shear test for the transverse ligament and the distraction test for the tectorial membrane in normal volunteers. MRI was performed in supine in neutral and end-range stress test positions in 16 individuals using proton density-weighted sequences and a standard head coil in a 3-T system. Measurements were made with respect to a strictly standardised protocol. The anterior shear test was assessed using changes in atlantodental interval and distance from the anterior arch of the atlas to the posterior aspect of the odontoid process. Distraction testing for the tectorial membrane was assessed by changes in basion-dental interval and by direct measurement of the tectorial membrane. Differences were compared using Wilcoxon Sign Rank tests or paired t-test depending upon each variables assessment of normality. Anterior shear testing resulted in a 0.41 mm mean increase in atlantodental interval (p = 0.03) and 0.35 mm mean increase in axial plane distance (p = 0.05). Distraction testing for the tectorial membrane resulted in a 0.64 mm increase in basion-dental interval (p < 0.01) and a 1.11 mm increase in direct ligament length measurement (p = 0.02). Reliability of measurements ranged from moderate to substantial. These results indicate that these tests produce a consistent direct effect on the transverse ligament and the tectorial membrane which is consistent with their theorised mechanism for clinical use.

Relaxation Response of Lumbar Segments Undergoing Disc-Space Distraction

A biomechanical study of human cadaveric lumbar spine segments undergoing disc-space distraction for insertion of anterior lumbar interbody implants. To measure the distraction force and its relaxation during a period of up to 3 hours after disc-space distraction as a function of the distraction magnitude and disc level. Interbody implants depend on compressive preload produced by disc-space distraction (annular pretension) for initial stabilization of the implant-bone interface. However, the amount of preload produced by disc-space distraction due to insertion of the implant and its subsequent relaxation have not been quantified. Twenty-two fresh human lumbar motion segments (age: 51 ± 14.8 years) were used. An anterior lumbar discectomy was performed. The distraction test battery consisted of a tension stiffness test performed before and after each relaxation test, 2 distraction magnitudes of 2 and 4 mm, and a recovery period before each distraction input. The distraction forces and lordosis angles were measured. RESULTS.: Peak distraction force was significantly larger for the 4-mm distraction (431.8 ± 116.4 N) than for the 2-mm distraction (204.9 ± 55.5 N) (P < 0.01). The distraction force significantly decreased over time (P < 0.01), approximating steady-state values of 146.1 ± 47.3 N at 2-mm distraction and 289.8 ± 92.8 N at 4-mm distraction, respectively. The distraction force reduced in magnitude by more than 20% of peak value in the first 15 minutes and reduced by approximately 30% of the peak value at the end of the testing period. The spine segment relaxed by the same amount of force, regardless of the disc level (P > 0.05). The "tightness of fit" that the surgeon notes immediately after interbody device insertion in the disc space degrades in the very early postoperative period, which could compromise the stability of the bone-implant interface.

Diagnostic performance of clinical tests for sacroiliac joint pain

Background: An updated review of the diagnostic clinical tests available for sacroiliac joint (SIJ) pain has yet to be undertaken.Objective: To evaluate the diagnostic performance of clinical tests for SIJ pain based on a systematic review.Methods: Five electronic databases were searched. Studies that examined the SIJ pain provocation tests with sensitivity and specificity data in patients (age ⩾18 years) with non-specific, non-pregnancy related low back pain and/or buttock pain, with or without lower extremity symptoms, were selected. Studies related to SIJ dysfunction were excluded. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool has been used to evaluate the quality of all included studies.Results: Six studies were included in this systematic review and the QUADAS scores are similar for all selected studies. The diagnostic performance of most clinical tests was poor with low specificity (0·03–0·95), sensitivity (0·08–0·90), and positive likelihood ratio (0·3–1·4), when used in isolation. The thigh thrust is the most sensitive test (0·88), the distraction test is most specific (0·81), and the compression test has the strongest positive likelihood ratio (2·20). Three or more positive pain provocation tests showed optimal sensitivity (0·85–0·94) and specificity (0·78–0·79) values with high positive likelihood ratios (4·02–4·29).Conclusion: Pain location below the lumbosacral junction overlying the SIJ with at least three or more positive SIJ pain provocation tests (thigh thrust, distraction, and compression) should be considered for the clinical diagnosis of SIJ pain.

The effects of using a portable music player on simulated driving performance and task-sharing strategies

This study examined the effects of performing scrollable music selection tasks using a portable music player (iPod Touch™) on simulated driving performance and task-sharing strategies, as evidenced through eye glance behaviour and secondary task performance. A total of 37 drivers (18–48 yrs) completed the PC-based MUARC Driver Distraction Test (DDT) while performing music selection tasks on an iPod Touch. Drivers’ eye glance behaviour was examined using faceLAB eye tracking equipment. Results revealed that performing music search tasks while driving increased the amount of time that drivers spent with their eyes off the roadway and decreased their ability to maintain a constant lane position and time headway from a lead vehicle. There was also evidence, however, that drivers attempted to regulate their behaviour when distracted by decreasing their speed and taking a large number of short glances towards the device. Overall, results suggest that performing music search tasks while driving is problematic and steps to prohibit this activity should be taken.

Treatment of Patients With Degenerative Cervical Radiculopathy Using a Multimodal Conservative Approach in a Geriatric Population: A Case Series

Retrospective clinical case series. To describe the management of 10 patients with advanced cervical spondyloarthrosis with radiculopathy, using manual therapy, intermittent mechanical cervical traction, and home exercises. Predictors and short-term outcomes of cervical radiculopathy have been published. These predictors have not been developed for, or applied to, geriatric patients with spondylitic radiculopathy. A series of 10 patients (aged 67 to 82 years) were referred to a physical therapist for medically prediagnosed cervical spondyloarthrosis and radiculopathy, as determined by magnetic resonance imaging. Neck Disability Index (NDI), numeric pain rating scale (NPRS), upper limb tension testing, Spurling's test, and the cervical distraction test were all completed on each patient at initial examination and at discharge. NDI and NPRS data were also collected at 6 months posttreatment. Intervention included manual therapy (including high-velocity low-amplitude thrust manipulation) of the upper thoracic and cervical spine, intermittent mechanical cervical traction, and a home program (including deep cervical flexor strengthening) for 6 to 12 sessions over a period of 3 to 6 weeks. All 10 patients had substantial improvement in NPRS and NDI scores. The mean NPRS score was less than 1/10, and the mean NDI score was 6/50 at discharge, compared to the original mean NPRS and NDI scores of 5.7 and 27.4, respectively. All patients reported maintaining those gains for 6 months. A multimodal approach for patients diagnosed with cervical spondyloarthrosis with radicular symptoms was useful in this geriatric population to reduce pain, minimize radicular symptoms, and improve functional outcomes. Therapy, level 4.

Behavioral and physiological predictors of guide dog success

A range of mobility aids are available to assist people living with vision impairment, and of these, guide dog ownership offers them several unique benefits. However, training a dog to be a successful guide dog comes at a high cost (approximately AU$30,000). Therefore, the aim of this study was to determine whether temperament testing and kennel behavior measures could be used by Guide Dog Organizations for the early identification of dogs suitable for guiding work and thus to reduce production costs. Temperament tests (Passive and Noise, Sudden Appearance, and Dog Distraction Tests) and kennel behavior assessments (Activity Level, Salivary Immunoglobulin A Concentration, and Kennel Surveillance) were assessed in potential guide dogs (n = 25-113) at the Guide Dogs NSW/ACT Training Centre, Glossodia, New South Wales, Australia. Several significant predictors of guide dog success were identified. The presence of panting (P = 0.029) and licking (P = 0.005) when contrasted with baseline observations in the Dog Distraction Test, significantly reduced the probability of guide dog success. Success was also reduced with the latency for a dog to sit in the third Noise Test (P = 0.028), and when the time spent resting was reduced during the evening period (P = 0.018) in the Kennel Surveillance assessment. This study reports that 4 specific behavioral responses, which may reflect anxiety and restlessness, predict low suitability of dogs for guiding work. Through the identification of early predictors of guide dog success, resources can be more appropriately focused on dogs with a higher probability of success, whereas unsuitable dogs can be rehomed.

Some tactical-technological aspects in surgical treatment of distal metaepiphyseal injuries of the forearm bones

The authors analysed aspects of surgical treatment of distal metaepiphyseal fractures of the forearm bones by methods of plate osteosynthesis and transosseous distraction fusion. In compliance with modern tendencies to minimization of the size of implants and noninvasiveness of surgical operations, improved bone plates were used as a variant for a tactical-technological solution of the problem of osteosynthesis. A radiological distraction test is suggested for differentiation of indications for plate and transosseous distraction osteosynthesis.

Development of a clinical prediction rule to identify patients with neck pain who are likely to benefit from home-based mechanical cervical traction

The objective of the study was to identify the population of patients with neck pain who improved with home-based mechanical cervical traction (HMCT). A prospective cohort study was conducted in a physical therapy clinic at a local hospital. Patients with neck pain referred to the clinic for physical therapy were included in the study. A HMCT program was given to participants for 2weeks. The patient's demographic data, Numerical Pain Scale (NPS) score, Neck Disability Index (NDI) and Fear-Avoidance Beliefs Questionnaire score were collected, and standard physical examination of the cervical spine was conducted before intervention. The NPS score, NDI and a global rating of perceived improvement were collected after the intervention was completed. A total of 103 patients participated in the study and 47 had a positive response to HMCT. A clinical prediction rule with four variables (Fear-Avoidance Beliefs Work Subscale score<13, pre-intervention pain intensity≥7/10, positive cervical distraction test and pain below shoulder) was identified. With satisfaction of at least three out of four variables (positive likelihood ratio=4.77), the intervention's success rate increased from 45.6% to over 80%. It appears that patients with neck pain who are likely to respond to HMCT may be identified.

Meditation therapies for attention-deficit/hyperactivity disorder (ADHD).

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common developmental disorders experienced in childhood and can persist into adulthood. The disorder has early onset and is characterized by a combination of overactive, poorly modulated behavior with marked inattention. In the long term it can impair academic performance, vocational success and social-emotional development. Meditation is increasingly used for psychological conditions and could be used as a tool for attentional training in the ADHD population. To assess the effectiveness of meditation therapies as a treatment for ADHD. Our extensive search included: CENTRAL, MEDLINE, EMBASE, CINAHL, ERIC, PsycINFO, C2-SPECTR, dissertation abstracts, LILACS, Virtual Health Library (VHL) in BIREME, Complementary and Alternative Medicine specific databases, HSTAT, Informit, JST, Thai Psychiatric databases and ISI Proceedings, plus grey literature and trial registries from inception to January 2010. Randomized controlled trials that investigated the efficacy of meditation therapy in children or adults diagnosed with ADHD. Two authors extracted data independently using a pre-designed data extraction form. We contacted study authors for additional information required. We analyzed data using mean difference (MD) to calculate the treatment effect. The results are presented in tables, figures and narrative form. Four studies, including 83 participants, are included in this review. Two studies used mantra meditation while the other two used yoga compared with drugs, relaxation training, non-specific exercises and standard treatment control. Design limitations caused high risk of bias across the studies. Only one out of four studies provided data appropriate for analysis. For this study there was no statistically significant difference between the meditation therapy group and the drug therapy group on the teacher rating ADHD scale (MD -2.72, 95% CI -8.49 to 3.05, 15 patients). Likewise, there was no statistically significant difference between the meditation therapy group and the standard therapy group on the teacher rating ADHD scale (MD -0.52, 95% CI -5.88 to 4.84, 17 patients). There was also no statistically significant difference between the meditation therapy group and the standard therapy group in the distraction test (MD -8.34, 95% CI -107.05 to 90.37, 17 patients). As a result of the limited number of included studies, the small sample sizes and the high risk of bias, we are unable to draw any conclusions regarding the effectiveness of meditation therapy for ADHD. The adverse effects of meditation have not been reported. More trials are needed.

A Laparoscopic‐Sutured Gastropexy Technique In Dogs: Mechanical and Functional Evaluation

To describe a laparoscopic-sutured gastropexy technique in dogs and evaluate the tensile strength of the adhesion and effects on gastric function. Experimental study. Female beagle dogs (n=7). A laparoscopic-sutured gastropexy technique was evaluated by ex vivo tensile distraction tests 10 weeks after surgery. The effect of the adhesion on gastric emptying, mucosal permeability, and systemic inflammation were evaluated by monitoring the C-reactive protein (CRP) and sucrose permeability, and by radiographic evaluation of gastric emptying 2 weeks before and 10 weeks after surgery. Mean (+/-SD) tensile force to disrupt adhesions was 51.1+/-16.4 N. There was no significant postoperative increase in CRP concentration or change in sucrose permeability. The area under the curve representing the postprandial decrease in gastric radiographic area increased by 11% after gastropexy. This laparoscopic gastropexy technique had appropriate mechanical and functional characteristics with limited morbidity. This laparoscopic-sutured gastropexy provides adhesion strength comparable with other gastropexy techniques tested at 10 weeks postoperatively. Only minor changes in gastric emptying were observed 10 weeks after surgery.

Unsuspected coagulopathy rarely prevents IV thrombolysis in acute ischemic stroke

American Heart Association/American Stroke Association guidelines recommend initiating treatment with IV tissue plasminogen activator (tPA) in acute ischemic stroke patients without suspected coagulopathy prior to availability of clotting results; however, little or no data support this practice. We sought to identify how often blood clotting abnormalities were responsible for withholding IV tPA at our institution. We conducted a retrospective review of our prospectively acquired Get With the Guidelines Stroke database from January 2003 to April 2008. All patients underwent clinical evaluation by a neurologist, diagnostic neuroimaging, and laboratory testing on admission. We classified patients with absolute contraindications to IV tPA as ineligible, and those with warnings/relative contraindications or potentially treatable factors as potentially eligible. Of 2,335 considered for analysis, 470 (20.1%) patients presented to our emergency department (ED) within 3 hours. Among these, 147 (31.3%) received IV tPA in our ED, 102 (21.7%) had an absolute contraindication, and 221 (47%) had a reason to consider withholding tPA. Only 30/470 (6.4%) of potential thrombolysis patients were discovered to have international normalized ratio > or =1.7 or platelets < or =100,000/microL, and of these, 28 were suspected a priori due to known coagulopathy from medication or illness. Only 2/470 (0.4%) patients had an unsuspected coagulopathy that ultimately prevented thrombolysis. Based on the experience of a large thrombolysis referral center, stroke patients without suspected clotting abnormality can safely begin thrombolytic therapy before clotting results are available. These data support the current practice guidelines, and may reassure clinicians that the benefits of early administration greatly outweigh the risks due to an unsuspected bleeding diathesis.