The extensive utilization of lithium-ion (Li-ion) batteries within the automotive industry necessitates rigorous measures to ensure their mechanical robustness, crucial for averting thermal runaway incidents and ensuring vehicle safety. This paper introduces an innovative methodology aimed at homogenizing the mechanical response of Li-ion batteries under compression load, using Finite Element Method (FEM) techniques to improve computational efficiency. A novel approach is proposed, involving the selective application of compression loads solely to the Jelly Roll and its casing, achieved by cutting the battery heads. Through this method, distinct mechanical behaviors are identified within the battery force displacement curve: an elastic region, a zone characterized by plastic deformation, and a segment exhibiting densification. By delineating these regions, our study facilitates a comprehensive understanding of the battery’s mechanical response under compression. Two battery models were employed in this study: one representing the battery as a solid volume, and another featuring the jelly roll as a solid volume enclosed by a shell representing the casing. The material utilized was LS Dyna MAT24, chosen for its piecewise characteristics’ definition, and its validation was primarily conducted through the curve fitting method applied to the force–displacement curve, taking in account the three regions of the compression force behavior. This approach not only optimizes computational resources but also offers insights crucial for enhancing the mechanical stability of Li-ion batteries in automotive applications.