This study aimed to assess the bi-axial flexural strength of two dual-polymerizing resin luting agents cemented to human dentin when photo-activated with different light-curing units. Two dual-cured resin cements: choice (CH) and Variolink II (VL) were tested. Hybrid composite resin (Z-250) discs (12×1.5mm) were fabricated. Three types of light-curing units were used halogen-curing unit (QTH), light-emitting diode (LED) and plasma arc (PAC). Sixty dentin discs of 0.5mm thickness were prepared from extracted human teeth. A circular mold (2.5mm in height and 12mm diameter) was utilized to create supporting structure for dentin, resin cement complex. The resin luting cement (0.5mm) was placed on the previously prepared dentin discs and covered with the prefabricated composite discs. Photo-activation of cements was performed for 40s with QTH and LED units and for 3s with PAC. The specimens were divided into 12 groups (20 specimens for each light source). Six groups were kept in distilled water for 24h and the rest were stored for 6weeks. Bi-axial flexural strength was determined using Instron machine. The data was analyzed using two-way ANOVA and Tukey test for comparison. The findings indicated that the bi-axial flexural strength values for both cements CH and VL were higher for 24h over 6weeks but not statistically significant when cured with QTH. Meanwhile, when LED light was used for photo-activation the cements, the flexural strength values reported were statistically higher of 24h over 6weeks storage at P=0.4(E-6) However, PAC light did not record any statistically significant difference between two duration for the CH cement although when used for polymerization of VL the reported value for 6weeks were statistically significantly higher value than 24h duration at P=0.002. When high immediate flexural strength is preferred in clinical situation photo-activation the cements with LED reported the greatest value.