BackgroundThe distal radius is the most common site of fracture in childhood, and the conservative treatment is widely used. The major casting complication is the loss of reduction and the redisplacement of the fracture. HypothesisAccording to the risk factors, close reduction and casting is the gold standard as first option of treatment of distal radius fractures (DRFs). MethodsAccording to 1-week X-ray, 101 pediatric conservatively treated for DRFs patients were divided into 2 groups: Group A (non-displaced) and Group B (secondary displacement). The sample underwent radiographic follow-ups at the emergency room, 1, 2 and 6 weeks after-treatment. The radiographic assessment included initial translation grade, following Mani criteria; initial reduction quality; if there were fractures of both bones; and the cast (CsI), padding (PI), canterbury (CaI), gap (GI), and three-point (3PI) indices. ResultsGroup A had 16 Mani grade III–IV initial translations; 37 anatomic reductions (47.4%); 48.7% fractures of both bones; and index means of CsI: 0.8, PI: 0.2, CaI: 1.0, GI: 0.16, and 3PI: 0.9. Group B had 13 Mani grade III–IV initial translations; 3 anatomic reductions (13.0%); 65.2% fractures of both bone; and index means of CsI: 0.9, PI: 0.3, CaI: 1.2, GI: 0.18, and 3PI: 1.0. The overall odds ratio indices were CsI: 4.7, CaI: 4.8, GI: 2.4, PI: 3.2, and 3PI: 3.6. ConclusionThe study hypothesis was partially confirmed: Casting is a simple, safe, effective, and inexpensive treatment DRFs in childhood. In our opinion, after a good-quality reduction, conservative treatment should be the gold standard for non-displaced and <50% of displaced fractures. CsI, PI, and CaI calculations are recommended as secondary displacement predictors. Level of evidenceIII, retrospective case control study.