Consulting Fee: Arthrex, Acumed (Huang) Speakers Bureau: Arthrex, Acumed (Huang) Ownership Interest: Stock in Imagen Technologies (Hanel) The Aptis total DRUJ prosthesis is a semiconstrained implant designed for treatment of DRUJ arthritis and instability. There are limited published studies assessing outcomes of patients undergoing the Aptis total DRUJ arthroplasty, with reports of favorable outcomes with 95% or greater 5-year survival rates.1-5 The purpose of this study is to analyze short-term complications of the Aptis total DRUJ prosthesis. A retrospective chart review of patients undergoing Aptis DRUJ arthroplasty from 2007-2015 at a single institution was performed. Patient demographics including gender, age, etiology of injury, occupation, and prior surgical procedures were collected. Records were analyzed for complications and need for subsequent surgical procedures. Radiographs were evaluated for radiographic evidence of implant loosening, periprosthetic fracture, and heterotopic ossification. Fifty-one Aptis DRUJ arthroplasties were performed over eight years by two hand surgeons at one institution. Twenty-two complications necessitating operative management occurred in 18 of 51 patients (35%). A total of 32 procedures were undertaken to address these complications (Table 22-1). Complications requiring revision surgery included 5 periprosthetic fractures (Fig. 22-1), 3 infections, 2 implant component failures, 2 instances of aseptic loosening, and 2 cases of heterotopic ossification at the DRUJ. Five of the 51 implants (10%) were explanted with three (6%) removed due to infection. •Complications of Aptis DRUJ arthroplasty are common, with 35% (18/51) of cases requiring additional surgical procedures.•The most common complications were periprosthetic fractures, infections necessitating explant, neuromas, and elbow pain from increased forearm motion.•Demographics including age, smoking, etiology of injury, worker’s compensation, and number of prior procedures did not have a significant impact on rate of complications.•There is a need for prospective studies on functional outcomes in this patient population.Table 22-1Procedures Performed after Replacement of DRUJ – Related to ComplicationsRevision of Aptis Components Explant4 Simultaneous explant and revision arthroplasty1 Delayed revision arthroplasty2 Poly exchange1 Revision for screw failure1 Revision for aseptic loosening of screws and radial peg1ORIF for periprosthetic fracture5Repair of distal radius nonunion1I&D4Neuroma excision Dorsal cutaneous branch ulnar nerve2 PIN neurectomy1Tenolysis EDC tenolysis1 Extensor tenolysis with ECU transposition1Excision of ectopic bone DRUJ2Elbow procedures HO excision of joint capsule1 Radial head arthroplasty1 Revision radial head arthroplasty1 Manipulation under anesthesia1Creation of a one bone forearm Proximal RUJ arthrodesis (from instability after DRUJ arthroplasty explant)1 Open table in a new tab