Purpose: The purpose of this study was to explore the impact of emotional labor on burnout in stroke patients' caregivers. Methods: Data were collected from 141 paid caregivers working at 3 hospital across Gyeonggi province from January to April 2014. Results: The caregivers' level of emotional labor showed 2.9/5.0 points and burnout, 2.5/5.0. A significant correlation was found among attentiveness to required display rules (p=.007), emotional dissonance (p=.001) and burnout. In a multiple regression, age (β=.279, p=.001) and emotional dissonance (β=.193, p=.046) were associated with burnout in caregivers. These factors attributed to 16.9% of variance in the burnout of caregivers. Conclusion: These results suggest that burnout in stroke patients' caregivers can be influenced by emotional dissonance as well as physical condition such as age. Accordingly, it is necessary to be develop support program to deal with mental labor to improve their mental health and lighten their workload for caregivers.