Display Platform Research Articles

A customization design platform for school uniforms using the Kano model

PurposeThis study aims to explore a methodology based on the Kano model. And use this method to determine user requirement attributes in the field of school uniform customization. To construct a set of processes that can be used as a reference for constructing a clothing customization platform.Design/methodology/approachAn optimized quantitative Kano model was applied. Initially, a survey was conducted to assess the current market for customized school uniforms in China. Subsequently, a Kano attribute questionnaire was developed, and experts from both supply and procurement sectors were invited to evaluate it. This was followed by categorizing user demands based on the Kano model’s evaluation criteria and conducting a validity analysis using Cronbach’s alpha coefficient. The priority ranking of user demands was determined through a sensitivity analysis of better-worse coefficients. Ultimately, a platform was established, and a fuzzy comprehensive evaluation was conducted.FindingsRegarding user demands, procurement-side demand elements prioritize modular design, fabric libraries and online reviews. In contrast, supply-side demand elements focus on style product libraries, layout adaptation to user habits and the preview effects of 3D models. Elements such as qualification verification, personal information uploading, design draft archiving and main tag categorization have a lesser impact on user satisfaction.Originality/valueThe results of the study provide a complete methodological reference for the construction of a garment customization platform. By applying the Kano model, this study categorizes and filters the demands of users for school uniform customization design platforms in China and establishes a 3D virtual display platform aimed at improving user satisfaction.

Air Quality Monitoring System Based Internet Of Things

This research aims to develop an Internet of Things (IoT)-based air quality monitoring system using the ESP8266 module along with DHT11 and MQ135 sensors. The system is designed to monitor temperature, humidity, and the concentration of harmful gases in the air, with real-time results accessible through the Blynk application on Android devices. The DHT11 sensor measures temperature and humidity, while the MQ135 sensor detects air quality based on concentrations of harmful gases such as carbon dioxide (CO2) and ammonia. Data from these sensors is transmitted to an IoT platform for real-time display. The research methodology follows a prototype model, starting with planning, system modeling, hardware development, and finally, system testing. During testing, the DHT11 and MQ135 sensors demonstrated accuracy in measuring temperature, humidity, and pollutant levels. Results show that the system functions as expected, with sensors responsive to environmental changes such as increases in temperature or pollutant levels. Additionally, the Blynk platform allows users to monitor air quality remotely and receive notifications if air quality reaches hazardous levels. This system is expected to be applicable in environments that require continuous air quality monitoring, such as hospitals, offices, or other enclosed spaces. The study’s findings indicate that this IoT-based air quality monitoring system effectively detects rapid changes in air quality, contributing to environmental health efforts and raising public awareness about the importance of clean air.

The Application of Computer-Aided Film and Television Art Design Elements in Exhibition Space Design

Exhibition spaces are where human civilization is passed along, science and culture are disseminated, and new design concepts and techniques are assimilated to better them over time. Several offline and online exhibitions have been affected, stopped, postponed, or relocated online due to the effect of the outbreak. Presently, the development and enhancement of virtual exhibition halls is underway. Visitors to exposition halls are no longer limited to those from the immediate area; rather, an increasing number of people come from all over the nation and even from other countries. Due to this, pavilions that are equipped with remote tour features become very influential. The cloud exhibition of the film and television art design elements is the focus of this study, and it additionally builds a virtual display platform and presents 3D Imaging and Virtual Reality Technology (3DIVRT). Through the lens of 3D modeling technology and virtual exhibition hall building, this study first investigates the application trend and preliminary practice of digital design in virtual exhibition halls domestically and internationally. A comparison is made between virtual exhibition halls and conventional exhibition halls to summarize the benefits and possibilities of virtual exhibition halls. Second, it elaborates on the features of the 3D experience found in virtual exhibition halls from immersion, interaction, and conceivability perspectives. A fundamental examination and comparison of 3D modeling software is carried out, and Blender and Unity’s impact on the execution of the virtual exhibition hall is detailed. Synchronizing virtual reflection by computational capabilities, which will be identified with certain examples from across the globe, requires multimedia to be successful. Various methods to exhibit activity that uses computer-aided technologies are brought to light in this research study. According to the findings and conclusions, manual presentation and technical distinctions are how artistic and reflective features can be achieved.

Bibliometric Analysis of Traditional Chinese Medicine in the Treatment of Asthma from 2005 to 2024

Asthma is a complex chronic respiratory disease that affects most people worldwide and imposes a heavy economic and health burden. Traditional Chinese medicine (TCM) is one of the common treatments for asthma; however, there is a lack of bibliometric analysis data on the relationship between bronchial asthma and traditional Chinese medicine. This study analyzes and visualizes current research status and future trends. Relevant English publications on traditional Chinese medicine treatment for bronchial asthma were collected from the Web of Science core collection, and bibliometric analysis was conducted using software like Histcite. A total of 406 articles meeting the criteria were included after manual screening. China (including Taiwan) emerged as the leading contributor, with the Beijing University of Chinese Medicine being the institution with the highest number of publications. 'Journal of Ethnopharmacology' was a significant publication in this domain. The most frequently occurring keyword on the main display platform was 'airway inflammation.' Future research hotspots are expected to focus on intestinal flora and metabolism. This research offers a fresh perspective for understanding developments in this field.

Enhancing vertical assembly of Dot-LEDs for display application using metal chelate coordination chemical linkers

The chemical linker assembly technique for dot-LEDs described in this study offers practical solutions to critical challenges in micro-LED display production, such as high costs, low yield in mass transfer processes, and high cost of micro-LED chips. Dot-LEDs feature a cylindrical structure with a diameter ranging from 0.75 to 1.35 μm and an aspect ratio of 1.1∼1.2 for height to diameter. We introduce a viable approach using N-(carboxymethyl)-N-(11-mercaptoundecyl)glycine (gly-thiol) chemical linkers for the face-selective vertical assembly of dot-LEDs. The size scale of dot-LED enables solution assembly processes when manufacturing pixels. By bonding the Au surface of the p-GaN face to the bottom Au electrodes using the chelate bond of Au-gly-thiol-Zn2+-gly-thiol-Au, we intend to enhance the face-selective vertical assembly. The process involves forming two chelate coordination bonds of Zn2+ ion surrounded by a gly-thiol-treated dot and bottom electrodes, achieving over 60 % efficiency in face-selective vertical assembly. We achieved bright and uniform dot-LED electroluminescence devices, with a peak external quantum efficiency (EQE) of 8.1 % at 3.4 V and a luminance of 22,387 cd/m2 at 9.0 V. Our findings suggest substantial improvements in the assembly and efficiency of micro-nano-scale dot-LED displays, providing a display platform technology for their application in future display systems.

Advances in personalized modelling and virtual display of ethnic clothing for intelligent customization

Abstract To enhance the intelligence of the ethnic clothing customization industry and provide online solutions for clothing ordering and fashion shows, this study analyses the latest developments in the fields of digital human models, 3D clothing models, and virtual clothing displays in recent years. This study focuses on analysing the categories and processes of three related technologies in clothing virtual display and compares the advantages and disadvantages of four human body modelling methods. Reshaping the facial features of a 3D body scan model and binding the bones of each part is key to providing a personalized body model. In addition, 3D clothing modelling technology is classified into three methods. The 3D fabric scan data are used to establish realistic seam information and process details simulation and use hybrid modelling methods to virtually sew 2D samples, which can enhance the realism of clothing models. The virtual display platform for ethnic clothing is constructed through layered design based on the Unity3D engine, matching versions and virtual display. The above research ideas can solve bottleneck problems in clothing customization. This has important guiding significance for opening up the ethnic clothing customization market, promoting the intelligence of the customization industry, and promoting ethnic clothing culture.

Extracellular vesicle surface display of αPD-L1 and αCD3 antibodies via engineered late domain-based scaffold to activate T-cell anti-tumor immunity.

Extracellular vesicles (EVs) are emerging as promising carriers for the delivery of therapeutic biologics. Genetic engineering represents a robust strategy for loading proteins of interest into EVs. Identification of EV-enriched proteins facilitates protein cargo loading efficiency. Many EV-enriched proteins are sorted into EVs via an endosomal sorting complex required for transport (ESCRT)-dependent pathway. In parallel, viruses hijack this EV biosynthesis machinery via conserved late domain motifs to promote egress from host cells. Inspired by the similarity of biogenesis between EVs and viruses, we developed a synthetic, Late domain-based EV scaffold protein that enables the display of a set of single chain variable fragments (scFvs) on the EV surface. We named this scaffold the Late domain-based exosomal antibody surface display platform (LEAP). We applied the LEAP scaffold to reprogramme HEK293T cell-derived EVs to elicit T-cell anti-tumor immunity by simultaneously displaying αPD-L1 and αCD3 scFvs on the EV surface (denoted as αPD-L1×αCD3 bispecific T-cell engaging exosomes, BiTExos). We demonstrated that αPD-L1×αCD3 BiTExos actively redirected T cells to bind to PD-L1+ tumor cells, promoting T-cell activation, proliferation and tumoricidal cytokine production. Furthermore, the αPD-L1×αCD3 BiTExos promoted T-cell infiltration into the tumor microenvironment to mitigate the tumor burden in vivo. Our study suggested that the LEAP scaffold may serve as a platform for EV surface display and could be applied for a broad range of EV-based biomedical applications.

Full‐Phase Parameter Modulation with Arbitrary Polarization Combination via Bidirectional Asymmetric Transmission Meta‐Devices

AbstractThe bidirectional asymmetric transmission (BAT) meta‐devices have attracted widespread attention as an emerging display, encryption, and information storage platform. Generally, the multiplexing capability of BAT meta‐devices determines the upper limit of the loading capacity of multi‐task integrated systems. However, existing BAT meta‐devices still depend on structural properties and the arrangement of meta‐atoms, limiting the number of manipulated channels, operating frequency, and polarization combinations. Herein, a universal BAT meta‐device, enabling bidirectional eight‐phase‐channel asymmetric transmission, composed of bilayer spatially cascaded birefringent metasurfaces (BMs) is proposed to allow for arbitrary polarization combination via the inverse design method and validated in the microwave region. In addition, the polarization multiplexing capabilities of BAT meta‐devices are further extended via a Lego‐like physical mechanism. The proposed design strategy may facilitate BAT meta‐devices functional innovation and advanced application deployment in holographic images, duplex communication, and secret‐key‐sharing data encryption.

Novel specific TCRs targeting KRASG12V-related cancers.

e14528 Background: KRAS mutations act as oncogenic drivers in a variety of tumors, such as pancreatic, colorectal and lung cancer. Among these, the KRASG12V mutation, being one of the most common mutations, is associated with adverse outcomes in patients. KRAS has been regarded as an “undruggable” target, and no clinical trials targeting tumors carrying shared KRASG12V mutation have been initiated. Notably, KRASG12D specific TCR-T has shown high effectiveness, including the regression of metastases in patients with pancreatic cancer. Therefore, TCR-engineered T cells could be a promising strategy for the treatment of solid tumors harboring G12V mutation. Methods: We have developed an innovative approach to rapidly and sensitively identify natural TCRs from single T cell derived from patients using CorreGene’s Single T cell TCR Cloning platform, thus obviating the requirement for NGS sequencing and TCR gene synthesis. Additionally, natural TCRs can be refined with SMART-TCR system, utilizing T cell reporter cell lines to construct a high-throughput T-cell Display Platform for functional screening of TCRs. This system is meticulously designed to enrich TCRs with superior potency and specificity from a natural TCR mutation library. We performed a thorough assessment of each TCR identified, evaluating them across both in vitro and in vivo settings. Results: In the present study, we identified three natural TCRs from patients' TILs, designated as KVA11-N01, KVA11-N02 and KVA11-N04 respectively, that specifically recognized the HLA-A*11:01-restricted KRAS G12V epitope. KVA11-N01 exhibited lower affinity and potency, prompting us to develop an affinity-optimized variant, KVA11-M01-231, using the SMART-TCR system. For comparison, we used the murine TCR TRAV3-301/BV401, identified by NCI from HLA-A11:01 transgenic mice immunized with KRAS G12V7-16, as a benchmark. Three of our TCRs, including KVA11-N02, KVA11-N04 and the engineered KVA11-M01-231, outperformed TRAV3-301/BV401 in both in vitro and in vivo assays. These three TCRs exhibited excellent expression intensity and stability on T cells, and notably, their IFN-γ release potency surpassed that of TRAV3-3*01/BV4*01. Furthermore, in vivo experiments confirmed the significant tumor suppression efficacy of our TCRs in a tumor-bearing mouse model, showing enhanced tumor growth inhibition compared to TRAV3-301/BV401. TCRs from Corregene’s platform exhibited exceptional specificity, with no allo-reactivity, no reaction to KRASG12V-negative cell lines, and no off-target effects. Additionally, all our TCRs demonstrates favorable tolerance in mice during in vivo studies. Conclusions: TCRs via Corregene’s Single T cell TCR Cloning platform and SMART-TCR system showed significantly excellent anti-tumor activities with great specificity and offers a promising solution for the treatment of KRASG12V-related cancers.

Establishment of a digital electrocardiogram telemonitoring system and remote consultation service.

The use of telemonitoring electrocardiogram (ECG) improves the detection rate of various arrhythmias as it offers an extended recording time and does not impose activity restrictions. However, many community hospitals lack the resources to conduct this test due to a lack of cardiac function specialists and antiquated screening equipment. To establish a digital ECG telemonitoring system and remote consultation service between tertiary hospitals and community medical service stations to improve diagnosis and treatment effectiveness. We used the PI ECG telemonitoring data acquisition system, with a personal digital assistant (PDA) or computer serving as the platform for ECG acquisition, storage, display, printing, and transmission. We introduced this system to standardize the storage and transmission of ECG telemonitoring data, and ensure accurate transmission, reproducibility, and preservation of data. The implementation of the PI ECG telemonitoring data acquisition system enabled the sharing of remote ambulatory electrocardiography data between Beijing Shijitan Hospital and its affiliated community hospitals. This has resulted in reduced waiting times for patients to receive reports (from 0.3 to 1 hour, to 0.1 or less), shortened consultation times (from 2 hours to 0.1 hour), and improved patient satisfaction with consultations (> 20% of the patients reported they were highly satisfied). The system successfully combined the goals of intelligence, real-time synchronization, and efficiency, revolutionizing ECG telemonitoring diagnosis in the network era. Sharing digital telematics information between tertiary and community hospitals enables a tiered approach to diagnosis and treatment and allows for more efficient, accurate, and convenient remote diagnostics.

Logically integrating exo/endogenous gated DNA trackers for precise microRNA imaging via synergistic manipulation

Nanomaterials provide an ideal platform for biomolecular display due to their dimensions approach the molecular scale, facilitating binding behavior akin to that observed in solution-based processes. DNA nanoprobes hold great promise as miniature detectives capable of detecting miRNAs within cells. However, current nanoprobes face a challenge in achieving the required precision for accurate miRNA detection, particularly within the intricate confines of the cellular microenvironment, due to interference with biological autofluorescence, off-target effects, and a lack of spatiotemporal control. Here, we have designed a dual-stimuli responsive DNA tracker, synergistically utilizing specific intracellular cues and external triggers, which enables spatiotemporal-controlled and precise detection and imaging of miRNAs "on demand". The tracker, which combines zeolitic imidazolate framework-67 (ZIF-67) and unique hairpin DNA structures, effectively anchored onto the ZIF-67 through electrostatic interactions, remains in a dormant state until activated by abundant cellular ATP, resulting in the release of the hairpin structures that include a PC linker incorporated into the loop region. Subsequent irradiation triggers specific recognition of the target miRNA. The newly developed HP-PC-BT@ZIF-67 tracker demonstrates precise spatiotemporal miRNA detection and exhibits excellent biocompatibility, enabling specific miRNA recognition "on demand" within cancer cells. This research presents a reliable miRNA imaging platform in the intricate cellular environment, opening up the possibilities for precise biomedical analysis and disease diagnosis.

Use of a Novel Beyeonics One Three-dimensional Head-mounted Digital Visualization Platform in Vitreoretinal surgeries.

Ophthalmic microscopes have been crucial in visualizing surgical fields, but their limitations in enhancing the surgical view through digital image processing have prompted the development of digital surgical microscopes. The Beyeonics One microscope, a novel digital microscope, offers ophthalmic surgeons a 3D visualization platform and an augmented reality (AR) surgical headset, potentially improving surgical decision-making and outcomes. While its initial use has been described in cataract and corneal surgeries, its application in vitreoretinal surgery remains relatively unexplored. In this interventional case series, we collected data from the medical records of patients who underwent vitreoretinal surgery using the Beyeonics One 3D visualization platform at the Tel Aviv Medical Center. A total of 36 eyes from 36 subjects were included. Surgical techniques included retinal detachment surgeries and macular surgeries, performed by experienced surgeons. The surgical visualization was facilitated by the Beyeonics One 3D head-mounted display (HMD) platform. The procedures were uneventful, and none intra- or postoperative complications were reported, and surgeons did not experience any signal delay in the real-time video. The Beyeonics One microscope offers several potential advantages in vitreoretinal surgery, including digital image processing, enhanced depth perception through the 3D HMD platform, and hands-free image control using head gestures. While this study demonstrates the feasibility and safety of the Beyeonics One microscope, addressing limitations related to hazy views and optimizing image quality are crucial for consistent visualization.

Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library.

RNA provides the genetic blueprint for many pathogenic viruses, including SARS-CoV-2. The propensity of RNA to fold into specific tertiary structures enables the biomolecular recognition of cavities and crevices suited for the binding of drug-like molecules. Despite increasing interest in RNA as a target for chemical biology and therapeutic applications, the development of molecules that recognize RNA with high affinity and specificity represents a significant challenge. Here, we report a strategy for the discovery and selection of RNA-targeted macrocyclic peptides derived from combinatorial libraries of peptide macrocycles displayed by bacteriophages. Specifically, a platform for phage display of macrocyclic organo-peptide hybrids (MOrPH-PhD) was combined with a diverse set of non-canonical amino acid-based cyclization modules to produce large libraries of 107 structurally diverse, genetically encoded peptide macrocycles. These libraries were panned against the -1 programmed ribosomal frameshifting stimulatory sequence (FSS) RNA pseudoknot of SARS-CoV-2, which revealed specific macrocyclic peptide sequences that bind this essential motif with high affinity and selectivity. Peptide binding localizes to the FSS dimerization loop based on chemical modification analysis and binding assays and the cyclic peptides show specificity toward the target RNA over unrelated RNA pseudoknots. This work introduces a novel system for the generation and high-throughput screening of topologically diverse cyclopeptide scaffolds (multiplexed MOrPH-PhD), and it provides a blueprint for the exploration and evolution of genetically encoded macrocyclic peptides that target specific RNAs.

A bacteriophage virus-like particle vaccine against oxycodone elicits high-titer and long-lasting antibodies that sequester drug in the blood

Opioid use disorder (OUD) and opioid overdoses are public health emergencies. In 2021, 80,000 opioid overdose associated deaths were reported in the United States. Despite the availability of treatment strategies, including medications for opioid use disorder (MOUD) and naloxone, opioid overdoses continue to increase at an alarming rate. Opioid vaccines are a novel approach to combat the growing crisis with several candidates recently entering human clinical trials. In this study, we investigated Qβ bacteriophage virus-like particles (VLPs) as a vaccine platform for immunogenic display of oxycodone. A derivative of oxycodone was conjugated to pre-formed Qβ VLPs using a sulfhydryl-amine reactive heterobifunctional crosslinker with high loading of oxycodone. In mice, intramuscular immunization with Qβ-oxycodone elicited high-titer, high-avidity and long-lasting antibody responses. Qβ-oxycodone was also immunogenic after storage at ambient room temperature for over two weeks, demonstrating that the vaccine is highly thermostable. In mice, immunization with Qβ-oxycodone elicited antibodies that sequester oxycodone in the serum, an important mechanism for preventing the adverse effects of opioid activity. Finally, Qβ-oxycodone is immunogenic in nonhuman primates, eliciting serum oxycodone antibodies after intramuscular immunization of rhesus macaques. These data establish Qβ-oxycodone as a promising opioid vaccine candidate.

Optimization of the visual communication path of data news in the context of the Internet

Abstract Visual news belongs to a kind of data news, which uses emerging technology to bring users a new reading experience and improve the news dissemination effect. In this paper, we utilize the self-attention mechanism and BiLSTM model to extract the content of data news documents and select and classify the audio features of data news by the AdaBoost algorithm. ResNet50 is used as the backbone network, combined with multiple residual unit modules for news multi-scale image feature extraction, and the text, audio and image features of the data news are fused by constructing a multimodal feature adaptive fusion model to further optimize the visual display of the data news. This paper verifies the model’s effectiveness for the data news visualization technique through multiple perspectives, including training loss curve, performance comparison, and ablation experiment. The results show that the loss value of the model based on the Self-Attention-BiLSTM model for news text feature extraction is 0.211 after 150 iterations. The AdaBoost-based news audio feature classification method has an average classification accuracy of 97.56% for the positive diagonal when the noise is raised from 0dB to 30 dB. By adding the residual unit module to the ResNet50 backbone network, the accuracy of the multi-scale image feature extraction model has been improved by 2.77% compared to the single backbone network. The information age requires the full integration of technology and news and combining the corresponding Internet platform for the visual display of data news in order to promote the expansion of the visual communication path of data news.

Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

Understanding cellular decisions due to receptor–ligand interactions at cell–cell interfaces has been hampered by the difficulty of independently varying the surface density of multiple different ligands. Here, we express the synthetic binder protein SpyCatcher, designed to form spontaneous covalent bonds with interactors carrying a Spytag, on the cell surface. Using this, we show that addition of different concentrations and combinations of native Spytag-fused ligands allows for the combinatorial display of ligands on cells within minutes. We use this combinatorial display of cell surface ligands—called CombiCells—to assess T cell antigen sensitivity and the impact of T cell co-stimulation and co-inhibition receptors. We find that the T cell receptor (TCR) displayed greater sensitivity to peptides on major-histocompatibility complexes (pMHC) than synthetic chimeric antigen receptor (CARs) and bi-specific T cell engager (BiTEs) display to their target antigen, CD19. While TCR sensitivity was greatly enhanced by CD2/CD58 interactions, CAR sensitivity was primarily but more modestly enhanced by LFA-1/ICAM-1 interactions. Lastly, we show that PD-1/PD-L1 engagement inhibited T cell activation triggered solely by TCR/pMHC interactions, as well as the amplified activation induced by CD2 and CD28 co-stimulation. The ability to easily produce cells with different concentrations and combinations of ligands should accelerate the study of receptor–ligand interactions at cell–cell interfaces.

Construction of a platform for displaying dialectalized graphic design based on virtual reality technology

Abstract This paper uses a semantic analysis of dialects, and a dialect word vector model is constructed. Based on the dialect word vector, the visual translation graphics of the language are used as the basic element to realize dialectalized graphic design. Secondly, the feature point matching is combined with the SIFT algorithm, where the key point is to elaborate the projection transformation matrix by the polar geometry and solve the projection transformation matrix. Then, the Jacobi determinant determines the image distortion to determine the contrast correction of the two graphics. A dialectalized graphical display platform uses virtual reality technology to achieve human-computer interaction. After testing the platform, it was obtained that the error rate generated by the display method was between 0.9 and 1.3%, the display accuracy was about 95.8%, the running time required for the display method was between 2.8s and 3.9s, and the platform display performance was good.

Yeast Surface Dual Display Platform for Rapid Discovery of Shark VNAR from a Semi-Synthetic Library Followed by Next-Generation Sequencing

The shark-derived single-domain antibody VNAR (variable domain of new antigen receptor) has many advantageous features that make the VNAR suitable for improving current monoclonal antibody therapy deficiencies or disease diagnosis methods. In order to discover more VNARs, it is necessary to improve the efficiency of the isolation process. This research aims to enhance the VNAR discovery platform by dual displaying the semi-synthetic VNAR library and green fluorescent protein tag on the yeast surface. The GFP tag can be used to determine the degree of VNAR expression. The diversity of the semi-synthetic VNAR library constructed in this study is verified to be 1.97 × 109 by next-generation sequencing (NGS). We conveniently screened VNARs against the feline neonatal Fc receptor or feline infectious peritonitis virus nucleocapsid protein by sequential MACS and FACS. To find more diverse VNARs, we analyzed the NGS data of VNAR CDR3 genes before and after biopanning. By comparing the frequency change of each sequence, we found that the amplification factor of sequences was increased by biopanning. Four VNAR candidates selected by the high-frequency and high-amplification factor criteria showed an antigen-binding ability. The results demonstrate that biopanning from a yeast surface displaying a semi-synthetic VNAR library followed by the NGS assay can generate antigen binders rapidly without the need for shark rearing and long-term immunization.

Humanoid Intelligent Display Platform for Audiovisual Interaction and Sound Identification

HighlightsA humanoid intelligent display platform (HIDP) is created using stretchable and resilient ionotronic materials, and can be applicable in extreme environments and complex mechanical stimulations.HIDP links sound amplitude and brightness through machine learning for audiovisual interaction.HIDP identifies and displays animal species and corresponding frequencies in real-time.

Transfer-Printing Hydrogel-Based Platform for Moisture-Driven Dynamic Display and Optical Anti-Counterfeiting.

Humidity-responsive materials offer a promising approach to achieving tunable metasurface systems due to their fast and reversible swelling responses to moisture, which enables many important applications, such as real-time humidity sensing, optical switches, dynamic displays, and optical information encryption. However, the humidity-responsive structural coloration generally cannot provide a high spatial resolution and requires a complex patterning process. Here, we present a scalable moisture-driven color-changing Fabry-Pérot (FP)-like cavity composed of a polyvinyl alcohol layer sandwiched between an upper gold nanoparticles assembly and a bottom gold mirror. Through nanoparticle contact printing, we pixelated these cavities with sub-micrometer sizes without crosstalk and achieved an ultrahigh display resolution of ∼400 nm. Meanwhile, these nanoparticle-based FP (NBFP) cavities exhibit more vibrant colors than those of conventional film-based ones due to broadband absorption of the disordered nanoparticle assembly. Moreover, the NBFP cavities exhibit a rapid response (<300 ms), benefiting from the membrane pores formed in the gaps between the adjacent nanoparticles. Finally, we demonstrated the applications of the NBFP cavities in optical anti-counterfeiting and dynamic multi-color printing. These results suggest that our approach will help to realize a colorful, fast, and ultrahigh-resolution dynamic display device in optical security and colorimetric sensing.