Shock Disorders Research Articles

Community and health care involvement to controlling and Management of dengue fever in Pakistan

In recent years, dengue has become a shared infection transmitted by mosquitoes, one of the main international health problems. In broad spectrum clinical manifestations, symptomatic dengue virus can occur from gentle febrile sickness to hazardous shock disorder. As a contribution to the manifestation of the disease, both the viral factor and the host have an important role in each infection. It is significant to realize the burden of mortality and morbidity in health care. Early intuition and dengue fever diagnosis in primary health care services can minimize complications if managed appropriately. We must apprehend the intensity of the complication in in relation to clinical picture, treatment, transmission, diagnosis and prevention. Keywords: Dengue, clinical features, pathogenesis, diagnosis, treatment. DOI : 10.7176/JMPB/62-07 Publication date: December 31 st 2019

State of the histamine?Histaminase system in the course of traumatic shock

The histamine content and diamine oxidase activity in the blood and tissues were studied in dogs in the course of evolution of traumatic shock. Phasic changes were found in histaminase activity which led to the development of excessively high histamine levels during the development of traumatic shock. Imbalance between monoamines and histamine is considered to play an important role in the genesis of the hemodynamic and central disorders in shock.