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Abstract
The histamine content and diamine oxidase activity in the blood and tissues were studied in dogs in the course of evolution of traumatic shock. Phasic changes were found in histaminase activity which led to the development of excessively high histamine levels during the development of traumatic shock. Imbalance between monoamines and histamine is considered to play an important role in the genesis of the hemodynamic and central disorders in shock.
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