Disorders In Adolescent Girls Research Articles

The Relationship Of Stress Level With Menstrual Cycle Disorders In SMK Health Nafsiah Stabat Year 2022

High and continuous stress can endanger the health of adolescents, where adolescents are the forerunners of the nation's successors. The future of the nation is in their hands. Adolescent girls as teenagers besides being the nation's successors in the field of development also play a role in giving birth to the next generation biologically. As the nation's successor, young women are expected to be healthy so that the quality of the nation's children is physically, psychologically and intellectually healthy. Normally, young women experience menstruation every month with a span of 21-35 days each time they menstruate. The normal menstrual cycle physiologically describes the reproductive organs that tend to be healthy and not problematic. When young women are stressed, it can cause menstrual cycle disorders, This study aims to determine the relationship between stress levels and menstrual cycle disorders in adolescent girls in grades X and XI at the Nafsiah Stabat Health Vocational School in 2022. The type of research used is descriptive correlation with a cross sectional study design. The research was conducted at the Nafsiah Stabat Health Vocational School with a sample of 34 people. Based on the results of the chi-square test using a computer, the results (p value) = 0.000 which is smaller than 0.05 can be concluded that Ho is rejected and Ha is accepted at a 5% significance level. So there is a relationship between stress levels and menstrual cycle disorders in adolescent girls at the Nafsiah Stabat Health Vocational School in 2022 at the level of confidence/significant (a) = 5% (0.05) obtained p value = 0.

Audio Visual Media-Based Health Education Increases Knowledge of Menstrual Disorders in Adolescence

Background: students' knowledge about menstrual disorders is still inadequate so that it will have an impact on disrupting learning activities, difficulty concentrating, mood changes, anemia, etc. So it is necessary to increase knowledge about menstrual disorders with interesting health education by using audio-visual media. Purpose: to determine the effect of health education with audio-visual media on knowledge of menstrual disorders in adolescents. Method s : this study used a pre-experimental design with a one-group pretest-posttest design. The sampling technique used proportional random sampling technique as many as 41 respondents, the sample selection used the lottery technique. The research instrument used is a questionnaire. Data analysis used the Wilcoxon test. Results: based on the results p -value = 0.000, it can be concluded that there is an effect of health education with audio-visual media on the level of knowledge about menstrual disorders in adolescent girls. Conclusion: it is needed that teenagers can increase their knowledge about menstrual disorders through reading books, electronics, or other printed media so that they can handle menstrual disorders when they occur.

The Relationship of Stress Levels on Menstrual Cycle Disorders in Adolescent Girls

Menstrual cycle abnormalities are a significant cause of infertility. Ovulation dysfunction accounts for 10-25% of female infertility cases. Data of youth care health services or Pelayanan Kesehatan Peduli Remaja (PKPR) at the Kota Dalam Public Health Center, Pesawaran Regency, in 2020, the number of adolescent girls was 728 people. 11.26% of adolescents have reproductive health problems, namely irregular menstrual cycles. This study aimed to determine the relationship between stress levels and menstrual cycle disorders in adolescent girls in the work area of the Kota Dalam Public Health Center, Pesawaran Regency, in 2021. This type of research was quantitative with an analytic design and cross-sectional approach. The population and sample of all adolescents girls were 38 people with the accidental sampling technique. The data analysis test used in this study used the Chi-Square test.The results showed that the distribution of the frequency of menstrual cycle disorders in adolescent girls, with the category of experiencing menstrual cycle disorders among as many as 18 respondents (47.40%), the distribution of stress frequencies in adolescent girls, with the variety of experiencing stress as many as 22 respondents (57.9%). There was a relationship between stress levels and menstrual cycle disorders in adolescent girls. The results of the analysis were obtained (p-value 0.010 less than 0.05). OR: 8,000. It is suggested that young women can increase their knowledge about menstrual cycle disorders through electronic media or by conducting examinations on health services to avoid complications in menstruation. Teenage girls who experience stress can be overcome by adequate rest, relaxation, regular exercise, recreation, and body massage. Abstrak: Kelainan siklus menstruasi merupakan penyebab infertilitas yang penting. Disfungsi ovulasi berjumlah 10-25% dari kasus infertilitas wanita. Berdasarkan data pelayanan kesehatan peduli remaja (PKPR) di Puskesmas Kota Dalam Kabupaten Pesawaran Tahun 2020, dari 728 orang remaja putri, terdapat sebanyak 11,26% remaja yangmengalami siklus menstruasi yang tidak teratur. Penelitian ini bertujuan untuk mengetahui hubungan tingkat stres terhadap gangguan siklus menstruasi pada remaja putri di wilayah kerja Puskesmas Kota Dalam Kabupaten Pesawaran Tahun 2021. Jenis penelitian kuantitatif dengan desain analitik dan pendekatan cross sectional. Populasi dan sampel seluruh remaja wanita sebanyak 38 orang dengan teknik accidental sampling. Uji analisis data yang digunakan pada penelitian ini menggunakan uji Chi-Square. Hasil penelitian diketahui remaja yang mengalami gangguan siklus menstruasi sebanyak 18 responden (47,40%), yang mengalami sebanyak 22 responden (57,9%). Ada hubungan tingkat stres terhadap gangguan siklus menstruasi pada remaja putri. Hasil analisis diperoleh ( p-value 0,010 kurang dari 0,05). OR: 8.000. Disarankan para remaja putri dapat lebih menambah pengetahuannya mengenai gangguan siklus menstruasi melalui media elektronik maupun dengan melakukan pemeriksaan pada pelayanan kesehatan untuk menghindari terjadinya komplikasi pada menstruasi. Remaja putri yang mengalami stres dapat diatasi dengan cara istirahat yang cukup, relaksasi, olahraga teratur, rekreasi, dan pemijatantubuh.

Sequencing of symptom emergence in anorexia nervosa, bulimia nervosa, binge eating disorder, and purging disorder in adolescent girls and relations of prodromal symptoms to future onset of these eating disorders.

To advance knowledge regarding the etiology of eating disorders, we characterized the sequencing of eating disorder symptom emergence for adolescent girls who subsequently developed anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD) for community-recruited adolescents and tested whether prodromal symptoms increased risk for future onset of each eating disorder. Data collected from adolescent girls (N = 496; M age = 13.02, s.d.= 0.73) who completed a diagnostic interview annually over an 8-year period were used to address these aims. For all four eating disorders, compensatory weight-control behaviors were the first behavioral symptom to emerge and weight/shape overvaluation was the first cognitive symptom to emerge. Moreover, lower-than-expected BMI predicted future AN onset, binge eating and all cognitive symptoms predicted future BN onset, weight/shape overvaluation predicted future BED onset, and compensatory behavior and all cognitive symptoms predicted future PD onset. These predictive effects were small-to-large in magnitude. Collectively, prodromal symptoms predicted an eating disorder onset with 83-87% accuracy. Results suggest that compensatory weight-control behaviors and weight/shape overvaluation typically emerge before other prodromal symptoms in all eating disorders during adolescence. Moreover, different prodromal symptoms seem to predict future onset of different eating disorders. Screening adolescent girls for these prodromal symptoms and implementing indicated prevention programs designed to reduce these symptoms may prove effective in preventing future onset of eating disorders.

Current issues of the research process as a component of the protection of the reproductive potential of adolescent girls

Background. The medical community extremely needs to conduct scientific research on topical issues of physiology, pathology of the formation of the reproductive system of the body and the organization of medical and preventive measures to preserve the reproductive potential of young people. The study was aimed to improve scientific and informational support for specialists in the field of child and adolescent health protection in pediatric gynecology. Materials and methods. There were studied the publications of research and dissertation works conducted in Ukraine in 2010–2020 in the field of “Pediatric Gynecology”; scientific journals devoted to topical issues of reproductive health of the female population; statistical materials of the Ministry of Health of Ukraine on the analysis of demographic processes. Information analytics methods were used to analyze them. Results. In Ukraine, research work on topical issues of pediatric gynecology is consistently carried out. During the study period (2010–2020), 23 research projects and 26 dissertations were conducted. According to their implementation, 195 articles, 196 abstracts were published in collections of scientific and practical conferences; 6 book publications, 12 methodological recommendations, 11 informational letters, 39 patents for inventions and utility models, 16 certificates of copyright registration were published. The thematic focus of research is presented as follows: pathophysiological mechanisms of formation of menstrual disorders in adolescent girls; disorders of menstrual function in the age aspect; the influence of socio-economic conditions on the formation of the reproductive system of girls and adolescents; new medical technologies in the field of reproductive health. Conclusions. Further research on the mechanisms of the development of gynecological diseases in adolescent patients in modern society will improve the system of preventive and rehabilitation measures to preserve reproductive potential and improve the quality of life of patients with disorders of the reproductive system.

Prevalence of eating disorders in adolescent girls in Siberia

IntroductionEating disorders (ED) are an urgent public health problem, however, many adolescents with clinical symptoms fail to meet stringent diagnostic criteria.ObjectivesTo estimate the prevalence of eating disorders (ED) and subthreshold eating disorders (SED) in adolescent girls.MethodsA cross-sectional study of girls attending secondary schools (n = 917) was carried out. The sample comprised of 18.3% early adolescents (aged 12-13), 51% middle adolescents (aged 14-15), and 30.6% late adolescents (aged 16-17). We used the Body Image and Eating Distress scale (Koskelainen et al., 2001) coded on a 1-3 scale. The answers were scored on a scale of 1-3. Adolescents scoring 12 or above on four items measuring body dissatisfaction were considered as dissatisfied with their bodies and were further divided into two subgroups: girls scoring 10 or above on three items measuring eating distress were considered as having ED, whereas girls scoring less than 10 were considered as having SED.ResultsThe prevalence of ED was 2.1% (CI 1.4-3.3), the prevalence of SED was 9.6% (CI 7.8-11.7). In early adolescence, the prevalence of SED was 1.6% (CI 0.9-2.7). In middle adolescence, the prevalence of SED was 5.1% (CI 3.9-6.7), the prevalence of ED was 0.9% (CI 0.5-1.8). In late adolescence, the prevalence of SED was 2.8% (CI 1.9-4.1), the prevalence of ED was 1.2% (CI 0.7-2.1).ConclusionsIn adolescent girls, the SED are 4.6 times commoner than overt above-threshold ED. During adolescence, the prevalence of SED decreases, while the prevalence of ED increases with age.DisclosureThe reported study was funded by grant RNF according to the research project № 21-15-00033

007 Pharmacological treatment of PCOS in adolescence

Polycystic ovary syndrome (PCOS) is a prevalent disorder in adolescent girls and young women. PCOS is commonly driven by ectopic (hepato-visceral or central) fat accumulation and insulin resistance which, in turn, are secondary to fat excess in subcutaneous adipose tissue.

Addressing Eating Disorders in Adolescent Girls and the COVID‐19 Pandemic (OWH)

Addressing Eating Disorders in Adolescent Girls and the COVID‐19 Pandemic (OWH)

Relationship Between Obesity and Menstrual Cycle Disorders in Adolescent Girls at SMP Al-Izzah International Islamic Boarding School Batu in 2021

Background: Results of the Riskesdas Nasional 2010 stated that as many as 13.7% of Indonesian women experienced menstrual cycle disorders. Menstrual cycle disorders in women, particularly in adolescent girls, needs special attention because they can have a long-term impact on their reproductive health. The most influential cause of menstrual cycle disorders is hormonal imbalance. This may be caused by several factors, including obesity. Therefore, this research is conducted to analyze the relationship between obesity and menstrual cycle disorders in adolescent girls. Method: This is observational analytic research with a cross-sectional research design. In 2021, 7th and 8th grade adolescent girls at SMP Al-Izzah International Islamic Boarding School Batu were sampled using the total sampling technique. A questionnaire with multiple questions about characteristics, nutritional status, and the menstrual cycle was used to gather the information needed for this research. Result: From a total of 202 respondents who filled out the research questionnaire, 19.8% were obese and 43.1% had menstrual cycle disorders. As many as 65% of 40 obese respondents suffered from menstrual cycle disorders. Hypothesis testing reveals a significant relationship between obesity and menstrual cycle disorders in adolescent girls (p = 0.002). Conclusion: Obesity influences the occurrence of menstrual cycle disorders in adolescent girls, and obese adolescent girls are up to 3.075 times more likely to have menstrual cycle disorders than non-obese adolescent girls.

FREQUENCY AND VARIANTS OF MENSTRUAL DISORDERS IN ADOLESCENTS WITH METABOLIC SYNDROME

The problem of the correlation between reproductive disorders and metabolic syndrome (MS) is well known, but data on the frequency and nature of these disorders among adolescents are extremely limited. The aim of the study: is to determine and analyze the frequency and structure of menstrual disorders in adolescent girls on the background of metabolic syndrome, as well as to study the correlation of these disorders with possible reproductive health disorders in the future. Materials and methods. To achieve this goal, a retrospective analysis of randomly selected 2,000 outpatient medical records (primary registration form № 025/o) of girls aged 10 to 18 years was performed at the Sumy Regional Clinical Perinatal Center from 2011 to 2021. The menstrual cycle was assessed according to the FIGO 2018 classification. Pathological menarche was defined as early (up to 10 years) or late (after 15 years) onset of menstrual function. Polycystic ovarian syndrome (РCOS) was diagnosed according to the Rotterdam criteria (2003): oligo‑ or anovulation (≤ 6 menstrual periods per year); clinical or laboratory hyperandrogenism (hirsutism/acne) and/or hyperandrogenemia (increased levels of free testosterone in the blood); polycystic ovaries during transvaginal ultrasound (≥ 15 follicles 2–9 mm in size in each ovary). Results. The results showed that in adolescent girls with overweight and MS, the frequency of menstrual dysfunction was observed in 71.1% of cases. Moreover, the most common variant of menstrual disorders in this category of patients was oligomenorrhea (60.0%), and the frequency of its manifestations was directly dependent on overweight degree. It was found that almost 82% of girls with confirmed MS had a high risk of developing polycystic ovarian syndrome (PCOS) in the future. Conclusion. It was found that the incidence of obesity in children and adolescents in the population was 27.1%, and the incidence of menstrual syndrome among children and adolescents with obesity was 41.5%. A significant proportion of adolescents with menstrual syndrome had menstrual irregularities – 71.1%, which was significantly higher than in healthy girls – 19%. Among menstrual disorders in girls with menstrual syndrome and obesity, oligomenorrhea prevailed (60.0% and 52%, respectively). Moreover, the frequency of oligomenorrhea was significantly affected by the degree of obesity. Almost 82% of girls with confirmed menstrual syndrome had at least two of the three criteria, which put them at high risk for developing polycystic ovarian syndrome in the future.

Trauma-Focused Cognitive Behavioral Therapy to reduce symptoms of post-traumatic stress disorder in adolescent victims of incest

Threats of sexual violence can occur anywhere, including in the family environment. The subject of this study was a fifteen-year-old adolescent girl diagnosed with post-traumatic stress disorder following an act of incest by her stepfather. This study aimed to examine the effectiveness of trauma-focused cognitive behavioral therapy to reduce symptoms of post-traumatic stress disorder in the subject. The study used the single case-single subject A-B-A design. The intervention was trauma-focused cognitive behavioral therapy administered over 12 sessions. Symptoms of post-traumatic stress disorder were measured using the Child Posttraumatic Stress Disorder Symptom Scale (CPSS). Changes in the CPSS scores in the intervention and post-intervention processes showed that the post-traumatic stress disorder score changed from the moderate to the mild category. The decrease in the score was also evidenced by the results of the different pre-intervention, intervention, and post-intervention CPSS scores using Mann-Whitney nonparametric analysis. The study has implications for applying trauma-focused cognitive behavioral therapy to reduce symptoms of post-traumatic stress disorder in adolescent girls who have been victims of incest.

E-Cigarette Dependence and Weight-Related Attitudes/Behaviors Associated With Eating Disorders in Adolescent Girls.

Background: Although numerous motivations for vaping have been identified in adolescents, no study to date has examined a possible link between vaping and attitudes/behaviors that are associated with eating disorders in adolescent females. Examining this question in adolescent females is especially relevant given the higher prevalence of eating disorders in adolescent girls and women compared to adolescent boys and men.Methods: We recruited 299 girls (between 13 to 17 years old) via Facebook advertisement to complete a REDCap survey, which included the Electronic Cigarette Dependence Index (ECDI), Minnesota Eating Behavior Survey (MEBS), and demographic questions. Data were analyzed using nonparametric Spearman rank correlation test in R.Results: Electronic Cigarette Dependence Index (ECDI) scores were correlated with weight preoccupation (WP), binge eating (BE) and compensatory behavior (CB), but not body dissatisfaction (BD). The following were the results of Spearman correlation tests: (1) WP: rho = 0.13, p = 0.02; (2) BD: rho = 0.06, p = 0.28; (3) BE: rho = 0.15, p = 0.0095; (4) CB: rho = 0.021, p = 0.00027.Conclusion: The present study adds to the current literature examining motivations for e-cigarette use in adolescent girls. As eating disorders and e-cigarette dependence are significant public health concerns, our results highlight the need for intervention development.

Effectiveness of Acceptance and Commitment Therapy on Reducing Body Image Disorders in Adolescent Girls

Background: Body image dissatisfaction and weight self-stigma are prevalent and are associated with physical and psychological ill-health. Acceptance and commitment therapy is increasingly used for both, yet little is known about its effectiveness. Objectives: This study aimed to determine the efficacy of acceptance and commitment therapy in reducing the body image disorder in adolescent girls. Methods: This study was quasi-experimental with pretest and posttest design with the control group. The statistical population of the study was all high school female adolescents with body image disorder; 280 girls were selected based on available sampling from 3 high schools in Ardabil City. Multidimensional Body-Self Relations Questionnaire (MBSRQ) scales were used to assess body image disorder and data were analyzed by SPSS software, version 19. Results: The results of this study indicated that this treatment was effective in reducing body image disorder in adolescent girls. Conclusions: Therefore, this treatment is suggested to reduce body image disorder in adolescent girls.

Efektivitas Modifikasi Perilaku Melalui Teknik Token Ekonomi Untuk Menurunkan Perilaku Conduct Disorder pada Remaja Putri

There is a lot of research about the Conduct Disorders in male subjects, but research on the Conduct Disorders in female subjects relatively minimal. The purpose of this study is to reveal the effectiveness of behavior modification to reduce Conduct Disorders behaviour in adolescent girls using token economy techniques. Research conducted on a teenager who suffered Conduct Disorders antisocial types, female, 16 years old, had no formal education, have a level of intelligence below the average. With single-subject research design with ABA-type single-factor baseline, the reduction behavior seen from a comparison between the results of the test before and after the intervention. The results showed a decrease in the aspect of aggressive behavior (14 points), attention problems (11 points), deliquent behavior (10 points), withdrawn (10 points), social problems (5 points), anxiety/depression (4 points) , thought problems (1 point), and somatic complaints (0 points). Thus the behavior modification using token economy technique effective to decrease the Conduct Disorders in adolescent girls.

Iodine Deficiency Disorder and Knowledge about Benefit and Food Source of Iodine among Adolescent Girls in the North Shewa Zone of Amhara Region.

Background As the dietary iodine content depends on the iodine contents of the soil where the crop is harvested, in highland areas where the iodine content of topsoil was washed away due to erosion, iodized salt is the main source of iodine. This study assessed the magnitude of iodine deficiency disorder and knowledge about the benefit and food sources of iodine among adolescent girls in the highland areas of the North Shewa Zone, Amhara Region, central Ethiopia. Methods An institutional cross-sectional study was conducted from October 5, 2018, to December 30, 2019. Through a multistage sampling technique, 625 adolescent school girls were selected from 9 schools. A pretested semistructured self-administered questionnaire was used for data collection. Anthropometric measures and thyroid gland physical examinations were performed by trained nurses. The collected data were entered into the computer through Epi Data 3.1 software, and analysis was performed using Anthro plus and SPSS software. Results The total goiter rate was 317 (50.7%) with 95%CI of 46.9% to 54.6%. Grade-one and grade-two goiter accounts 226 (36.2%) and 91 (14.6%), respectively. About one-third, 428 (68.5%), had knowledge about locally available iodine source foods and 309 (72.2%) of them mentioned salt as a source of iodine. Over half, 216 (55.1%), of 392 (62.7%) participants who had knowledge about the benefit of iodine knew it prevents goiter. Diet diversity score of <5 food groups [AOR 1.487, 95%CI 1.061–2.083], stunting [AOR 1.876, 95%CI 1.079–3.257], menstruation [AOR 1.615, 95%CI 1.110–2.349], rural residence [AOR 1.412, 95%CI 1.005–1.984], and open salt storage container [AOR 2.001, 95%CI 1.044–3.833] were significantly associated with goiter. Conclusions Total goiter rate of adolescent school girls is high in the area. Low diet diversity score, stunting, menstruation, rural residence, and using an open container for salt storage increased the risk of goiter. In addition to universal salt iodization, the emphasis has to be given on proper handling and utilization of iodized salts at the household level to avoid iodine deficiency disorder in adolescent girls.

Menstrual Pattern, Reproductive Hormones, and Transabdominal 3D Ultrasound in 317 Adolescent Girls.

The knowledge of normal variation of reproductive hormones, internal genitalia imaging, and the prevalence of gynecological disorders in adolescent girls is limited. The study aimed to describe reproductive parameters in postmenarchal girls from the general population including the frequency of oligomenorrhea, polycystic ovary syndrome, and use of hormonal contraception. The Copenhagen Mother-Child Cohort is a population-based longitudinal birth cohort of 1210 girls born between 1997 and 2002. University hospital. A total of 317 girls were included, with a median age of 16.1 years and time since menarche of 2.9 years. Tanner stage, height, weight, age at menarche, menstrual cycle length and regularity, ovarian/uterine volume, and number of follicles were recorded. Serum concentrations of FSH, LH, anti-Müllerian hormone (AMH), inhibin B, estradiol, testosterone, SHBG, androstenedione, dehydroepiandrosterone sulfate, 17-OH-progesterone, and IGF-1 were measured. Twenty girls (6.3%) had oligomenorrhea and differed significantly in serum androgens and AMH, age at and time since menarche from girls with regular cycles. Twenty-seven girls were classified with PCOS (8.5%) and had significantly higher 17-OH-progesterone, estradiol, AMH, LH, and age at menarche than the reference group. Girls on oral contraception had significantly higher serum SHBG concentrations and lower serum concentrations of all hormones except AMH and IGF-1. Ovarian follicles 2 to 29.9 mm correlated positively with serum AMH (P < 0.0001). Most 16-year-old girls had regular menstrual cycles, normal reproductive hormones, and uterine and ovarian ultrasound. Serum AMH reflected ovarian follicle count and may be a useful biomarker of ovarian reserve.

Five major factors of personality and positive and negative perfectionism as predictor of symptoms of body dysmorphic disorder in adolescent girls

پژوهش حاضر با هدف بررسی رابطه اختلال بدشکلی بدن با پنج عامل بزرگ شخصیت و کمال‌گرایی مثبت و منفی در دانشجویان دختر شهر شیراز انجام شد. مطالعه¬ی حاضر از نوع توصیفی-همبستگی و بر روی300 نفر از دانشجویان دختر 22-18سال شهر شیراز در دانشگاه فاطمیه و دانشگاه شیراز و به شیوه¬ی نمونه¬گیری دسترس انجام شد. ابزار گردآوری داده¬ها پرسش¬نامه¬های ترس از تصویر بدن لیتلتون (BICI, 2005 (، نئو فرم کوتاه پنج عامل بزرگ شخصیت(NEO-60) و پرسش¬نامه¬ی استاندارد کمال‌گرایی مثبت و منفی تری-شورت و پرسش¬نامه جمعیت¬شناختی بودند. داده¬ها توسط نرم¬افزار 21-spss مورد تجزیه و تحلیل قرارگرفتند. با¬توجه به نتایج تحلیل ضریب همبستگی پیرسون به دست آمده، نشان داد که بین متغیر¬های نوروز¬گرایی، توافق¬گرایی و برون¬گرایی با اختلال بدشکلی بدن همبستگی مثبت معنادار وجود دارد و بین متغیرهای وجدانی بودن و گشودگی با اختلال بدشکلی بدن همبستگی معناداری وجود ندارد. نتایج حاصل از یافته¬ها نشان داد از میان پنج عامل بزرگ شخصیت بین نوروز¬گرایی (بتا = 395/0) برون¬گرایی (بتا = 144/0) و توافق¬گرایی (89/0 = بتا) با اختلال بدشکلی بدن ارتباط مثبت معناداری وجود دارد. بین اختلال بدشکلی ‌بدن با کمال‌گرایی منفی رابطه‌ی معنادار دارد. همچنین نتایج تحلیل رگرسیون نشان داد که کمال‌گرایی منفی قوی¬ترین پیش¬بین برای اختلال بدشکلی بدن می¬باشد (477/ 0= بتا). علاوه¬بر این بین کمال‌گرایی مثبت با اختلال بدشکلی بدن رابطه غیرمستقیم وجود دارد (224/0 = بتا). بدین معنی که باافزایش مولفه¬ی کمال‌گرایی مثبت، اختلال بدشکلی بدن کاهش پیدا می¬کند. نتایج حاصل از یافته¬ها نشان داد از میان پنج عامل بزرگ شخصیت، سه عامل نوروز¬گرایی، برون-گرایی و توافق¬گرایی قوی¬ترین پیش¬بین ابتلا به اختلال بدشکلی بدن می¬باشد و همچنین کمال‌گرایی منفی می‌تواند موجب افزایش بروز اختلالات شود که این کمال‌گرایی منفی می‌تواند در ارتباط با متغیر صفات شخصیتی که از مولفه¬های مهم در پیش¬بینی اختلال بدشکلی بدن می¬باشد موجب‌ ایجاد و ‌‌تشدید اختلالات شود؛ درحالی صفات شخصیتی مطرح شده با کمال‌گرایی مثبت می‌تواند نتیجه¬ی عکس کمال‌گرایی منفی را بیان کند.

Роль кисспептина в нарушениях менструальной функции у девочек-подростков. Коррекция клинико-гормональных нарушений

Роль кисспептина в нарушениях менструальной функции у девочек-подростков. Коррекция клинико-гормональных нарушений

Features of the emotional portrait of teen-age girls in the context of their color-sensory attitude to modern communication technologies and state of anxiety.

This work is a continuation of previous studies on the relationship of high and the use of modern electronic communication tools. The purpose of this study was to determine the characteristics of the emotional portrait of adolescent girls in the – context of their color-sensory attitude to modern communication technologies and state of anxiety. The study involved 136 girls aged 17 years (at the time of the survey). All respondents were evaluated according to standardized valid psychological methods (WAM - well-being, activity and mood), color relationship test (TCR), the method of Multidimensional assessment of child anxiety (MACAQ), the personal Taylor manifestation scale in the modification of Norakidze) and contained an author's questionnaire regarding the time spent in a sitting position; time spent in front of the screen of a mobile phone, tablet, laptop, PC; problems in relationships with parents. The study was conducted in accordance with the bioethical principles and provisions of the Helsinki Declaration and Good Clinical Practice (GCP). In the course of the work, it was proved that the time spent near the screens of electronic devices (phone, tablet, laptop, PC) for more than 6 hours a day is a significant factor, which is a predictive of emotional disorders in adolescent girls due to disruption of compensation mechanisms and the formation of a high level of personal anxiety, the appearance of achromatic sensory-color associations in interpersonal interactions, exacerbation of family conflicts with parents, which together indicates maladaptation and requires disruption work corrective programs.

Low Circulating Levels of miR-451a in Girls with Polycystic Ovary Syndrome: Different Effects of Randomized Treatments.

Polycystic ovary syndrome (PCOS) is a prevalent disorder in adolescent girls, purportedly driven by hepato-visceral fat excess, and often followed by subfertility and type 2 diabetes. We studied the baseline microRNA (miRNA) profile of girls with PCOS, and the effects of a randomized treatment with an oral contraceptive (OC) or with spironolactone-pioglitazone-metformin (SPIOMET, aiming at loss of hepato-visceral fat excess) for 1 year. The miRNA profile was assessed by RNA sequencing in girls with PCOS who had participated in a randomized, open-label, single-center, pilot study (n = 31; age 15.7 years, body mass index (BMI) 23.1 kg/m2). Healthy age- and BMI-matched girls (n = 13) served as controls. Differentially expressed miRNAs were validated by RT-qPCR in the entire study population. Post-treatment ovulation rates were assessed by salivary progesterone in PCOS girls. Endocrinology Department, University Hospital. Girls with PCOS, compared with controls, had markedly reduced concentrations of circulating miR-451a, miR-652-3p, miR-106b-5p, and miR-206; pathway enrichment analysis showed that these miRNAs target genes involved in energy homeostasis and cell cycle control. In the present study, miR-451a could diagnose PCOS with 100% sensitivity and 100% specificity. SPIOMET (but not OC) was accompanied by on-treatment normalization of the miRNA profile in girls with PCOS; miR-451a concentrations after 1 year on OC or SPIOMET treatment associated closely (r = 0.66; P < .0001) with post-treatment ovulation rates. SPIOMET treatment for 1 year normalizes the miRNA profile of girls with PCOS. Circulating miR-451a may become a biomarker to guide the diagnosis and treatment of PCOS in adolescence.