Discrimination Algorithm Research Articles

ERGPNet: lesion segmentation network for COVID-19 chest X-ray images based on embedded residual convolution and global perception.

The Segmentation of infected areas from COVID-19 chest X-ray (CXR) images is of great significance for the diagnosis and treatment of patients. However, accurately and effectively segmenting infected areas of CXR images is still challenging due to the inherent ambiguity of CXR images and the cross-scale variations in infected regions. To address these issues, this article proposes a ERGPNet based on embedded residuals and global perception, to segment lesion regions in COVID-19 CXR images. First, aiming at the inherent fuzziness of CXR images, an embedded residual convolution structure is proposed to enhance the ability of internal feature extraction. Second, a global information perception module is constructed to guide the network in generating long-distance information flow, alleviating the interferences of cross-scale variations on the algorithm's discrimination ability. Finally, the network's sensitivity to target regions is improved, and the interference of noise information is suppressed through the utilization of parallel spatial and serial channel attention modules. The interactions between each module fully establish the mapping relationship between feature representation and information decision-making and improve the accuracy of lesion segmentation. Extensive experiments on three datasets of COVID-19 CXR images, and the results demonstrate that the proposed method outperforms other state-of-the-art segmentation methods of CXR images.

An integrated study fusing systems biology and machine learning algorithms for genome-based discrimination of IPF and NSIP diseases: a new approach to the diagnostic challenge

An integrated study fusing systems biology and machine learning algorithms for genome-based discrimination of IPF and NSIP diseases: a new approach to the diagnostic challenge

Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis: a cross-sectional study.

JOURNAL/nrgr/04.03/01300535-202408000-00039/figure1/v/2023-12-16T180322Z/r/image-tiff Biomarkers are required for the early detection, prognosis prediction, and monitoring of amyotrophic lateral sclerosis, a progressive disease. Proteomics is an unbiased and quantitative method that can be used to detect neurochemical signatures to aid in the identification of candidate biomarkers. In this study, we used a label-free quantitative proteomics approach to screen for substantially differentially regulated proteins in ten patients with sporadic amyotrophic lateral sclerosis compared with five healthy controls. Substantial upregulation of serum proteins related to multiple functional clusters was observed in patients with sporadic amyotrophic lateral sclerosis. Potential biomarkers were selected based on functionality and expression specificity. To validate the proteomics profiles, blood samples from an additional cohort comprising 100 patients with sporadic amyotrophic lateral sclerosis and 100 healthy controls were subjected to enzyme-linked immunosorbent assay. Eight substantially upregulated serum proteins in patients with sporadic amyotrophic lateral sclerosis were selected, of which the cathelicidin-related antimicrobial peptide demonstrated the best discriminative ability between patients with sporadic amyotrophic lateral sclerosis and healthy controls (area under the curve [AUC] = 0.713, P < 0.0001). To further enhance diagnostic accuracy, a multi-protein combined discriminant algorithm was developed incorporating five proteins (hemoglobin beta, cathelicidin-related antimicrobial peptide, talin-1, zyxin, and translationally-controlled tumor protein). The algorithm achieved an AUC of 0.811 and a P-value of < 0.0001, resulting in 79% sensitivity and 71% specificity for the diagnosis of sporadic amyotrophic lateral sclerosis. Subsequently, the ability of candidate biomarkers to discriminate between early-stage amyotrophic lateral sclerosis patients and controls, as well as patients with different disease severities, was examined. A two-protein panel comprising talin-1 and translationally-controlled tumor protein effectively distinguished early-stage amyotrophic lateral sclerosis patients from controls (AUC = 0.766, P < 0.0001). Moreover, the expression of three proteins (FK506 binding protein 1A, cathelicidin-related antimicrobial peptide, and hemoglobin beta-1) was found to increase with disease progression. The proteomic signatures developed in this study may help facilitate early diagnosis and monitor the progression of sporadic amyotrophic lateral sclerosis when used in combination with current clinical-based parameters.

The Performance of Discriminative Tracking Algorithms for the Sway Frequency Measurement of Betula platyphylla Sukaczev (Individual Branch and Tree) under Artificial and Natural Excitation

The sway frequency is an important component of the dynamic characteristics of trees. Video-based methods can be used to measure the sway frequencies of trees. The key to successfully measuring tree sway frequency using video methods lies in whether the tracking method employed is appropriate. Based on six algorithms, i.e., Boosting, TLD, MIL, KCF, MOSSE and CSR-DCF, the tracking performance and accuracy of tree sway frequency measurements were investigated under two conditions: artificial excitation and environmental excitation. The results show that the following: (1) In terms of the tracking speed of tree sway, MOSSE &gt; KCF &gt; CSR-DCF &gt; Boosting &gt; MIL &gt; TLD. (2) The TLD algorithm is not suitable for tree sway tracking. Boosting, MIL, MOSSE, KCF and CSR-DCF can be used for tree sway tracking. (3) Boosting, MIL and MOSSE are suitable for measuring the sway frequency of artificially excited branches and environmentally excited trees. (4) KCF and CSR-DCF algorithms are not suitable for the measurement of branch sway frequency under artificial excitation conditions but can be used for the measurement of tree sway frequency under environmental excitation conditions. However, it should be noted that this experiment only takes a Betula platyphylla Sukaczev tree and a Betula platyphylla Sukaczev branch as the research object to verify the effectiveness and feasibility of each tracking method, and does not verify the generalization ability of the above methods (on multiple tree species and multiple trees).

Dynamic modeling of photoacoustic sensor data to classify human blood samples.

The photoacoustic effect is an attractive tool for diagnosis in several biomedical applications. Analyzing photoacoustic signals, however, is challenging to provide qualitative results in an automated way. In this work, we introduce a dynamic modeling scheme of photoacoustic sensor data to classify blood samples according to their physiological status. Thirty-five whole human blood samples were studied with a state-space model estimated by a subspace method. Furthermore, the samples are classified using the model parameters and the linear discriminant analysis algorithm. The classification performance is compared with time- and frequency-domain features and an autoregressive-moving-average model. As a result, the proposed analysis can predict five blood classes: healthy women and men, microcytic and macrocytic anemia, and leukemia. Our findings indicate that the proposed method outperforms conventional signal processing techniques to analyze photoacoustic data for medical diagnosis. Hence, the method is a promising tool in point-of-care devices to detect hematological diseases in clinical scenarios.

Rapid and comprehensive grade evaluation of Keemun black tea using efficient multidimensional data fusion

To develop a comprehensive evaluation method for Keemun black tea, we used micro-near-infrared spectroscopy, computer vision, and colorimetric sensor array to collect data. We used support vector machine, least-squares support vector machine (LS-SVM), extreme learning machine, and partial least squares discriminant analysis algorithms to qualitatively discriminate between different grades of tea. Our results indicated that the LS-SVM model with mid-level data fusion attained an accuracy of 98.57% in the testing set. To quantitatively determine flavour substances in black tea, we used support vector regression. The correlation coefficient for the predicted sets of gallic acid, caffeine, epigallocatechin, catechin, epigallocatechin gallate, epicatechin, gallocatechin gallate and total catechins were 0.84089, 0.94249, 0.94050, 0.83820, 0.81111, 0.82670, 0.93230, and 0.93608, respectively. Furthermore, all compounds exhibited residual predictive deviation values exceeding 2. Hence, combining spectral, shape, colour, and aroma data with mid-level data can provide a rapid and comprehensive assessment of Keemun black tea quality.

Multi-frequency microwave dielectric properties-based method coupled with SPA-PLSDA algorithm for rapid discrimination of grain mildew

To achieve in-situ monitoring of the occurrence of grain mildew and ensure food safety, this study took paddy grains as the object and carried out the discrimination of paddy mildew based on microwave dielectric properties. The multi-frequency swept measurement technique was used to acquire the dielectric constant (DC) and dielectric loss factor (DLF) spectra (2.00–10.00 GHz) of healthy samples and samples with different moldy paddy content. To choose the most effective frequencies, 20 frequency subsets (DC subset 1–10, DLF subset 1–10) were generated by an algorithm coupled with the successive projections algorithm and partial least-squares discriminant analysis. Afterward, four key frequencies were determined from the 100 pairwise combinations of the two types of frequency subsets by exhaustive method. Dielectric properties at key frequencies and sample thickness were used as the input variables to establish the discriminating model for paddy mildew. The established microwave dielectric properties-based model achieved 100% accuracy in distinguishing healthy and moldy samples, showing perfect discriminant validity. Moreover, only 4.4% of those samples whose MPC was at a low level (≤30%) were misclassified by the model, and the discrimination model achieved 97.29% overall accuracy. The results of this study should encourage future research on dielectric-based mildew detection in food processing and agriculture-related industries.

Artificial neural network algorithm for pulse shape discrimination in 2πα and 2πβ particle surface emission rate measurements

Artificial neural network algorithm for pulse shape discrimination in 2πα and 2πβ particle surface emission rate measurements

Data augmentation using generative models for track intrusion detection.

The objective of this work is to address the problem of detecting track intruders in railway systems using deep learning-based algorithms. Unauthorized entry onto railway tracks poses a significant risk of collisions between trains and humans. However, intrusion discrimination algorithms often suffer from a lack of learning data and data imbalance issues. To overcome these challenges, this research proposes an algorithm that combines generative models and classification networks. Generative models are utilized to generate synthetic intrusion data by learning the underlying distribution of available data and creating new samples resembling the original data. The augmented intrusion data is then used to train deep neural networks to accurately identify intrusions. The proposed algorithm is evaluated using real data sets, demonstrating its effectiveness in overcoming limited learning data and data imbalance issues. By augmenting intrusion data using generative models, the algorithm achieves improved accuracy compared to traditional approaches. In conclusion, the algorithm presented in this work provides a solution for detecting track intruders in railway systems. By leveraging generative models to augment limited intrusion data and utilizing classification networks for intrusion discrimination, the algorithm demonstrates improved performance in accurately identifying intrusions. This research highlights the potential of deep learning-based approaches in enhancing railway safety and recommends further exploration and application of these methods in real-world settings.

Особенности функционирования СВЧ-радиометров в условиях внешних помех.

The influence of external disturbances on the sensitivity and dynamic range of the microwave radiothermograph is considered. The results of an experimental study of the interference situation in the range up to 3 GHz are presented. The diagram of the spectral density of interference adjacent to radio astronomy windows is analyzed. The features of real observed disturbances are investigated. The classification of possible disturbances according to their characteristics is given. Algorithms for discrimination of various types of interference are considered. The sensitivity and dynamic range of the microwave radiometer are evaluated using the pulse noise suppression algorithm.

The now and future of ChatGPT and GPT in psychiatry.

ChatGPT has sparked extensive discussions within the healthcare community since its November 2022 release. However, potential applications in the field of psychiatry have received limited attention. Deep learning has proven beneficial to psychiatry, and GPT is a powerful deep learning-based language model with immense potential for this field. Despite the convenience of ChatGPT, this advanced chatbot currently has limited practical applications in psychiatry. It may be used to support psychiatrists in routine tasks such as completing medical records, facilitating communications between clinicians and with patients, polishing academic writings and presentations, and programming and performing analyses for research. The current training and application of ChatGPT require using appropriate prompts to maximize appropriate outputs and minimize deleterious inaccuracies and phantom errors. Moreover, future GPT advances that incorporate empathy, emotion recognition, personality assessment, and detection of mental health warning signs are essential for its effective integration into psychiatric care. In the near future, developing a fully-automated psychotherapy system trained for expert communication (such as psychotherapy verbatim) is conceivable by building on foundational GPT technology. This dream system should integrate practical 'real world' inputs and friendly AI user and patient interfaces via clinically validated algorithms, voice comprehension/generation modules, and emotion discrimination algorithms based on facial expressions and physiological inputs from wearable devices. In addition to the technology challenges, we believe it is critical to establish generally accepted ethical standards for applying ChatGPT-related tools in all mental healthcare environments, including telemedicine and academic/training settings.

Orthodontic craniofacial pattern diagnosis: cephalometric geometry and machine learning.

Efficient and reliable diagnosis of craniofacial patterns is critical to orthodontic treatment. Although machine learning (ML) is time-saving and high-precision, prior knowledge should validate its reliability. This study proposed a craniofacial ML diagnostic workflow base on a cephalometric geometric model through clinical verification. A cephalometric geometric model was established to determine the landmark location by analyzing 408 X-ray lateral cephalograms. Through geometric information and feature engineering, nine supervised ML algorithms were conducted for sagittal and vertical skeleton patterns. After dimension reduction, plane decision boundary and landmark contribution contours were depicted to demonstrate the diagnostic consistency and the consistency with clinical norms. As a result, multi-layer perceptron achieved 97.56% accuracy for sagittal, while linear support vector machine reached 90.24% for the vertical. Sagittal diagnoses showed average superiority (91.60 ± 5.43)% over the vertical (82.25 ± 6.37)%, where discriminative algorithms exhibited more steady performance (93.20 ± 3.29)% than the generative (85.98 ± 9.48)%. Further, the Kruskal-Wallis H test was carried out to explore statistical differences in diagnoses. Though sagittal patterns had no statistical difference in diagnostic accuracy, the vertical showed significance. All aspects of the tests indicated that the proposed craniofacial ML workflow was highly consistent with clinical norms and could supplement practical diagnosis.

Application of classification machine learning algorithms for characterizing nutrient transport in a clay plain agricultural watershed

Excess nutrients in surface water and groundwater can lead to water quality deterioration in available water resources. Thus, the classification of nutrient concentrations in water resources has gained significant attention during recent decades. Machine learning (ML) algorithms are considered an efficient tool to describe nutrient loss from agricultural land to surface water and groundwater. Previous studies have applied regression and classification ML algorithms to predict nutrient concentrations in surface water and/or groundwater, or to categorize an output variable using a limited number of input variables. However, there have been no studies that examined the application of different ML classification algorithms in agricultural settings to classify various output variables using a wide range of input variables. In this study, twenty-four ML classification algorithms were implemented on a dataset from three locations within the Upper Parkhill watershed, an agricultural watershed in southern Ontario, Canada. Nutrient concentrations in surface water were classified using geochemical and physical water parameters of surface water and groundwater (e.g., pH), climate and field conditions as the input variables. The performance of these algorithms was evaluated using four evaluation metrics (e.g., classification accuracy) to identify the optimal algorithm for classifying the output variables. Ensemble bagged trees was found to be the optimal ML algorithm for classifying nitrate concentration in surface water (accuracy of 90.9%), while the weighted KNN was the most appropriate algorithm for categorizing the total phosphorus concentration (accuracy of 87%). The ensemble subspace discriminant algorithm gave the highest overall classification accuracy for the concentration of soluble reactive phosphorus and total dissolved phosphorus in surface water with an accuracy of 79.2% and 77.9%, respectively. This study exemplifies that ML algorithms can be used to signify exceedance of recommended concentrations of nutrients in surface waters in agricultural watersheds. Results are useful for decision makers to develop nutrient management strategies.

Machine-learning assisted multicolor platform for multiplex detection of antibiotics in environmental water samples

Antibiotic (AB) resistance is one of daunting challenges of our time, attributed to overuse of ABs and usage of AB-contaminated food resources. Due to their detrimental impact on human health, development of visual detection methods for multiplex sensing of ABs is a top priority. In present study, a colorimetric sensor array consisting of two types of gold nanoparticles (AuNPs) were designed for identification and determination of ABs. Design principle of the probe was based on aggregation of AuNPs in the presence of ABs at different buffer conditions. The utilization of machine learning algorithms in this design enables classification and quantification of ABs in various samples. The response profile of the array was analyzed using linear discriminant analysis algorithm for classification of ABs. This colorimetric sensor array is capable of accurate distinguishing between individual ABs and their combinations. Partial least squares regression was also applied for quantitation purposes. The obtained analytical figures of merit demonstrated the potential applicability of the developed sensor array in multiplex detection of ABs. The response profiles of the array were linearly correlated to the concentrations of ABs in a wide range of concentration with limit of detections of 0.05, 0.03, 0.04, 0.01, 0.06, 0.05 and 0.04 μg.mL–1 for azithromycin, amoxicillin, ciprofloxacin, clindamycin, cefixime, doxycycline and metronidazole respectively. The practical applicability of this method was further investigated by analysis of mixture samples of ABs and determination of ABs in river and underground water with successful verification.

A Chaotic Discriminant Algorithm for Arrival Traffic Flow Time Series Based on Improved Alternative Data Method

&lt;p&gt;Chaos discrimination is a prerequisite for the application of chaos theory modeling. Since the average orbital period of an air traffic flow system is long, it is difficult to obtain time series with a small time scale and many data points, so the Small-Data Method is often adopted to quantitatively calculate the chaotic characteristic quantity. However, when using the power spectrum method, it is found that the Small-Data Method is prone to false judgments when the data volume is small. To reduce spurious judgments, we apply a chaos discrimination algorithm based on an Improved Alternative Data Method combined with the Small-Data Method for air traffic flow and analyze it by example. The algorithm was experimentally demonstrated to correct the false judgment results of the Small-Data Method. In particular, when the data volume is only 150, the discrimination accuracy of the improved algorithm is as high as 80%, which is 26% higher than the discrimination accuracy of the Small-Data Method. Moreover, the improved algorithm has better discriminative performance than the Small-Data Method under the same data volume condition, which is suitable for the chaotic discriminative analysis of the arrival traffic flow time series.&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt;

All-in-one nanoflare biosensor combined with catalyzed hairpin assembly amplification for in situ and sensitive exosomal miRNA detection and cancer classification

Exosomal miRNAs can reflect tumor progression and metastasis, and are effective biomarkers for cancer diagnosis. However, the accuracy of exosomal miRNA-based cancer diagnosis is limited by the low sensitivity and complicated RNA extraction of traditional approaches. Herein, a novel biosensor is developed for in situ, extraction-free, and highly sensitive analysis of exosomal miRNAs via nanoflare combined with catalyzed hairpin assembly (CHA) amplification. Without cumbersome and costly miRNA extraction or transfection agents, nanoflare can directly enter the exosomes to bind target miRNAs and generate a fluorescence signal that can be amplified by the CHA reaction to achieve the in situ and highly sensitive detection of exosomal miRNAs. Under the optimal conditions, the detection limit of 5 aM is obtained for three exosomal miRNAs, which is an order of magnitude lower than quantitative real time polymerase chain reaction (qRT-PCR). In combination with the linear discriminant analysis algorithm, five exosomes are distinguished with 100% accuracy. Importantly, five cancers including breast, lung, liver, cervical, and colon cancer from 64 patients are distinguished with 99% accuracy by testing exosomal miRNAs in clinical plasma. This simple, accurate, and sensitive biosensor holds the potential to be expanded into clinical non-invasive cancer diagnostic tests.

Substantiation of Sequential Trait with Independent Correlation

Abstract: The expanding aquaculture sector can greatly benefit from having access to comprehensive fish information, which includes data on ecosystems, food requirements, and related details. Relational databases play a crucial role in storing the diverse range of fish species data in the aquaculture industry. However, due to the extensive variety of species and their associated data, organizing and categorizing this information can be a challenging task. Nonetheless, fishermen can derive significant advantages from visual representations of the data and a recommendation system that suggests the most suitable fish species and optimal ecological conditions. By leveraging data on fish species, names, taxonomy, and survival characteristics, a connected user can receive personalized recommendations based on their interests. The proposed system also offers appropriate food variety suggestions for the fish, ensuring scalability and effective generation of recommendations. Through the integration of information from multiple sources, a database system can efficiently process, manage, store, and retrieve relational data. Furthermore, implementing the linear discriminant algorithm enhances the accuracy and speed of food recommendations for fish.

Classification of cancer cells and gene selection based on microarray data using MOPSO algorithm.

Microarray information is crucial for the identification and categorisation of malignant tissues. The very limited sample size in the microarray has always been a challenge for classification design in cancer research. As a result, by pre-processing gene selection approaches and genes lacking their information, the microarray data are deleted prior to categorisation. In essence, an appropriate gene selection technique can significantly increase the accuracy of illness (cancer) classification. For the classification of high-dimensional microarray data, a novel approach based on the hybrid model of multi-objective particle swarm optimisation (MOPSO) is proposed in this research. First, a binary vector representing each particle's position is presented at random. A gene is represented by each bit. Bit 0 denotes the absence of selection of the characteristic (gene) corresponding to it, while bit 1 denotes the selection of the gene. Therefore, the position of each particle represents a set of genes, and the linear Bayesian discriminant analysis classification algorithm calculates each particle's degree of fitness to assess the quality of the gene set that particle has chosen. The suggested methodology is applied to four different cancer database sets, and the results are contrasted with those of other approaches currently in use. The proposed algorithm has been applied on four sets of cancer database and its results have been compared with other existing methods. The results of the implementation show that the improvement of classification accuracy in the proposed algorithm compared to other methods for four sets of databases is 25.84% on average. So that it has improved by 18.63% in the blood cancer database, 24.25% in the lung cancer database, 27.73% in the breast cancer database, and 32.80% in the prostate cancer database. Therefore, the proposed algorithm is able to identify a small set of genes containing information in a way choose to increase the classification accuracy. Our proposed solution is used for data classification, which also improves classification accuracy. This is possible because the MOPSO model removes redundancy and reduces the number of redundant and redundant genes by considering how genes are correlated with each other.

Recognition of high-frequency steady-state visual evoked potential for brain-computer interface

Coding with high-frequency stimuli could alleviate the visual fatigue of users generated by the brain-computer interface (BCI) based on steady-state visual evoked potential (SSVEP). It would improve the comfort and safety of the system and has promising applications. However, most of the current advanced SSVEP decoding algorithms were compared and verified on low-frequency SSVEP datasets, and their recognition performance on high-frequency SSVEPs was still unknown. To address the aforementioned issue, electroencephalogram (EEG) data from 20 subjects were collected utilizing a high-frequency SSVEP paradigm. Then, the state-of-the-art SSVEP algorithms were compared, including 2 canonical correlation analysis algorithms, 3 task-related component analysis algorithms, and 1 task discriminant component analysis algorithm. The results indicated that they all could effectively decode high-frequency SSVEPs. Besides, there were differences in the classification performance and algorithms' speed under different conditions. This paper provides a basis for the selection of algorithms for high-frequency SSVEP-BCI, demonstrating its potential utility in developing user-friendly BCI.

Acousto-optic modulator-based improvement in imaging through scattering media.

Reduced visibility is a common problem when light traverses through a scattering medium, and it becomes difficult to identify an object in such scenarios. What we believe to be a novel proof-of-principle technique for improving image visibility based on the quadrature lock-in discrimination algorithm in which the demodulation is performed using an acousto-optic modulator is presented here. A significant improvement in image visibility is achieved using a series of frames. We have also performed systematic imaging by varying the camera parameters, such as exposure time, frame rate, and series length, to investigate their effect on enhancing image visibility.