In this brief, we develop a novel model to study the cascading failure in cyber-physical power systems. We use a discrete packet traffic model that follows a specific routing strategy to describe the dynamic data transmission in the information network. Moreover, the dynamic load flow model that takes into account the power-frequency characteristics of loads and generators is applied to describe the dynamic flow process of the power network. Our proposed model allows to consider the impacts of data packet transmission failures and voltage-related failures in the cascading process. Furthermore, we analyze the effects of routing strategy and information network topology on the severity of cascading failure. Simulation results verify the applicability of the proposed model and reveal the way in which routing strategy affects the cascading failure of cyber-coupled systems. In addition, we show that when the main hub in the information network is used as a dispatching center, a spreadout degree distribution of the information network reduces the severity of cascading failure in the cyber-coupled system.