Logic Gates Research Articles

Data encryption/decryption and medical image reconstruction based on a sustainable biomemristor designed logic gate circuit

Memristors are considered one of the most promising new-generation memory technologies due to their high integration density, fast read/write speeds, and ultra-low power consumption. Natural biomaterials have attracted interest in integrated circuits and electronics because of their environmental friendliness, sustainability, low cost, and excellent biocompatibility. In this study, a sustainable biomemristor with Ag/mugwort:PVDF/ITO structure was prepared using spin-coating and magnetron sputtering methods, which exhibited excellent durability, significant resistance switching (RS) behavior and unidirectional conduction properties when three metals were used as top electrode. By studying the conductivity mechanism of the device, a charge conduction model was established by the combination of F-N tunneling, redox, and complexation reaction. Finally, the novel logic gate circuits were constructed using the as-prepared memristor, and further memristor based encryption circuit using 3-8 decoder was innovatively designed, which can realize uniform rule encryption and decryption of medical information for data and medical images. Therefore, this work realizes the integration of memristor with traditional electronic technology and expands the applications of sustainable biomemristors in digital circuits, data encryption, and medical image security.

Tunable cell differentiation via reprogrammed mating-type switching

This study introduces a synthetic biology approach that reprograms the yeast mating-type switching mechanism for tunable cell differentiation, facilitating synthetic microbial consortia formation and cooperativity. The underlying mechanism was engineered into a genetic logic gate capable of inducing asymmetric sexual differentiation within a haploid yeast population, resulting in a consortium characterized by mating-type heterogeneity and tunable population composition. The utility of this approach in microbial consortia cooperativity was demonstrated through the sequential conversion of xylan into xylose, employing haploids of opposite mating types each expressing a different enzyme of the xylanolytic pathway. This strategy provides a versatile framework for producing and fine-tuning functionally heterogeneous yet isogenic yeast consortia, furthering the advancement of microbial consortia cooperativity and offering additional avenues for biotechnological applications.

Efficient Characterization of Qudit Logical Gates with Gate Set Tomography Using an Error-Free Virtual Z Gate Model.

Gate set tomography (GST) characterizes the process matrix of quantum logic gates, along with measurement and state preparation errors in quantum processors. GST typically requires extensive data collection and significant computational resources for model estimation. We propose a more efficient GST approach for qudits, utilizing the qudit Hadamard and virtual Z gates to construct fiducials while assuming virtual Z gates are error-free. Our method reduces the computational costs of estimating characterization results, making GST more practical at scale. We experimentally demonstrate the applicability of this approach on a superconducting transmon qutrit.

Primordial Molecular 1-Bit Magnitude Comparator in consort with Excitation-Guided mouldable Logic Systems: A guided design of Regular Interactions between Molecules.

In addition to designing certain excitation modulated logic systems, we have created the first-ever genuine molecular 1-bit magnitude comparator, using acid and base guided varied absorption responses at separate channels. Designed and manufactured Bifunctional Bis(indolyl)methane Derivative (1) demonstrates distinct optical responses (in UV-visible and fluorescence mode) to a range of chemical stimuli (acid, base, Hg2+, Cu2+, EDTA, GSH, etc.) in aqueous medium. Intriguingly, the compound's excitation-modulated fluorescence responses appeared to change at different detection channels depending on whether the aforementioned analytes were present or not. We have proposed not only an excitation driven logic system with switchable molecular IMPLICATION and XNOR logic gates, but also a molecular 1-bit magnitude comparator in our proposal. A second excitation driven logic system with switchable molecular COMPLEMENT and NOR logic gates was also designed with two different optical channels and used Hg(II) & Cu(II) as chemical inputs.

Astrophotonics: recent and future developments

Astrophotonics is a burgeoning field that lies at the interface of photonics and modern astronomical instrumentation. Here we provide a pedagogical review of basic photonic functions that enable modern instruments, and give an overview of recent and future applications. Traditionally, optical fibres have been used in innovative ways to vastly increase the multiplex advantage of an astronomical instrument, e.g. the ability to observe hundreds or thousands of stars simultaneously. But modern instruments are using many new photonic functions, some emerging from the telecom industry, and others specific to the demands of adaptive optics systems on modern telescopes. As telescopes continue to increase in size, we look to a future where instruments exploit the properties of individual photons. In particular, we envisage telescopes and interferometers that build on international developments in quantum networks, the so-called quantum internet. With the aid of entangled photons and quantum logic gates, the new infrastructures seek to preserve the photonic state and timing of individual photons over a coherent network.

Boolean Logic Gate Operation in Bacteriorhodopsin of Purple Membrane Based on a Molten Globule-like State.

Bacteriorhodopsin (bR) of purple membrane (PM) has increasing technical interests, particularly in photonic devices and bioelectronics. The present work has concerned with monitoring the temperature dependence of passive electric responses in-plane and out-of-plane of the membranes. Based on thermal properties observed orthogonally here for PM, a high-temperature intermediate of bR has been suggested to populate at around 60 °C, which may be ascribed to a molten globule-like state. This intermediate has been found to be enclosed between two reversible thermal transitions for PM. Large-scale turnover in the energy of activation, for these two thermal transitions, occurs steeply at such state at 60 °C, above which does bR reverse the sign of dielectric anisotropy (i.e. crossover) provided the operating frequency should be above the crossover frequency, at which the reversal occurs. No such crossover was found to occur below the crossover frequency, even above the crossover temperature (i.e. 60 °C). Likewise, no such crossover was found to occur below the crossover temperature, even above the crossover frequency. Relying on this reasoning, a logic gate operation may be declared implicating bR for bioelectronics and sense technological relevance. In addition, the results specify "dual frequency" as well as "dual temperature" characteristics to bacteriorhodopsin.

Use of Molecular Logic Gates for the Tuning of Chemosensor Dynamic Range.

Dynamic range is a crucial aspect in the development of fluorescent chemosensors. We aimed to address this issue using molecular logic gates. By creating an AND logic gate with two binding sites for the same type of ion, we increased the dynamic range of a sodium chemosensor while still using the same ionophore. Naphthalimide derivatives 1 and 2 were synthesized to test the plausibility of this application. Being an AND logic gate, the second molecule requires two Na+ ions, while molecule 1 requires a single ion for sensing. The application of this molecular logic gate is a useful method of altering the chemosensor range.

Silver induced self-assembly of a rhodanine derived reversible fluorescent chemosensor: Applications in smart-phone color assist app, logic gate, real sample analysis and bio-imaging

An innovative chemosensor, Rhodanine-appended benzaldehyde (RB), was developed and analyzed using spectroscopic methods to detect silver ions (Ag+) in a THF–H2O buffer solution via fluorimetry. The RB probe exhibited low fluorescence due to C-N free rotation and inhibition of electron transfer. However, interaction with Ag+ ions resulted in a noteworthy redshift of approximately 6 nm and increased fluorescence intensity owing to the chelation-enhanced fluorescence (CHEF) effect, which hindered the Intramolecular Charge Transfer (ICT) process. The binding ratio between RB and Ag+ ions was determined to be 2:1 using the job plot method. The association constant (Ka) was calculated to be 4.84 × 105 M−1 and further confirmed through ESI-TOF spectroscopic and DFT analyses. The limit of detection (LOD) and quantification (LOQ) for RB in binding with Ag+ ions were found to be 1.7 × 10−8 M and 5.4 × 10−8 M, respectively. Additionally, the color changes of RB when binding with Ag+ ions were effectively leveraged in an RGB-assisted smartphone color analysis app for precise sample analysis for Ag+ ion detection. Most importantly, the RB probe’s ability to detect silver ions in the E. coli pathogen was successfully demonstrated, providing reassurance about its practical application, using a confocal scanning electron microscope via the green channel.

Hydrogel ionic diode with ultra-high rectification ratio for ionic circuit

Organisms transmit signals through complex ion systems, and signal transmission in artificial electronic circuits mainly depends on electrons. The development of rectifier ionic diode, grounded in ion transport principles, paves ways for artificial bionic circuit and seamless human–machine interaction. Among its pivotal performance indicators, the ion rectification ratio (IR) is of primal importance, facilitating enhanced ion selectivity, bolstered energy efficiency, and robust, high-performing operations. Here, hybrid hydrogel ionic diode based on chitosan (CS) doped with 5,10,15,20-tetrakis(4-aminophenyl)-21,23H-porphyrin (TAPP)/sodium polyacrylate (PAAs) doped with 5,10,15,20-tetrakis(4-sulfonatophenyl)-21,23H-porphyrin (TPPS) was constructed to achieve a high IR. This design achieved a remarkable feat by elevating the IR from 5.57 to an unprecedented 158.64, surpassing previous benchmarks set by hydrogel-based ionic diodes. Moreover, this study emphasizes the selectivity of polyelectrolytes to different porphyrin structures, as well as the charge properties of the groups carried by porphyrins. It delves into the fundamental mechanisms underpinning their interactions, providing a comprehensive understanding of their behavior. In order to demonstrate the excellent rectification characteristics and practical applicability of the CS-TAPP/PAAs-TPPS ionic diode, we successfully integrated it into the full-wave rectification and logic gate system. The full-wave rectifier can convert a 1.2 V sinusoidal voltage input to a 0.8 V full-wave voltage output. This shows the advantages of high IR ionic diodes. It offers insights for the development of high-performance hydrogel-based ionic diodes, and promotes the advancement of novel biomimetic devices and ionic circuits.

Stretchable Arduinos embedded in soft robots.

To achieve real-world functionality, robots must have the ability to carry out decision-making computations. However, soft robots stretch and therefore need a solution other than rigid computers. Examples of embedding computing capacity into soft robots currently include appending rigid printed circuit boards to the robot, integrating soft logic gates, and exploiting material responses for material-embedded computation. Although promising, these approaches introduce limitations such as rigidity, tethers, or low logic gate density. The field of stretchable electronics has sought to solve these challenges, but a complete pipeline for direct integration of single-board computers, microcontrollers, and other complex circuitry into soft robots has remained elusive. We present a generalized method to translate any complex two-layer circuit into a soft, stretchable form. This enabled the creation of stretchable single-board microcontrollers (including Arduinos) and other commercial circuits (including SparkFun circuits), without design simplifications. As demonstrations of the method's utility, we embedded highly stretchable (>300% strain) Arduino Pro Minis into the bodies of multiple soft robots. This makes use of otherwise inert structural material, fulfilling the promise of the stretchable electronic field to integrate state-of-the-art computational power into robust, stretchable systems during active use.

Bifunctional acoustic lossy coupler for broadband power splitting and absorption

In this work, we propose a bifunctional acoustic lossy coupler for broadband power splitting and absorption. Following the three-level system in quantum physics, the three-waveguide (WG) acoustic system is proposed to obtain efficient energy transfer behaviors. Given the agreement in form between Schr o¨ dinger equation and coupled mode equation, the time-dependent external fields are mapped into space-varying coupling actions between adjacent WGs. The propagation paths of the incident waves can be predicted by Schr o¨ dinger-like equation, which are verified by numerical simulations and experimental measurements. Owing to the different responses to lossy medium in WG B for WG A incidence and WG C incidence, the acoustic coupler can be considered as a broadband power splitter and muffler by selecting different input ports. Meanwhile, according to the reversibility of acoustic path, a switchable acoustic logic gate with functions of “OR” and “XOR” is constructed as well by taking advantage of the lossless adiabatic coupler, and the function can be controlled conveniently by reversing the phase of input waves from WG A or C. Our work provides a new scheme for the design of bifunctional acoustic coupler, which may have a profound impact on the development of non-resonance acoustic high-performance devices.

All-optical NOT, OR, and XOR Logic Gates Using Silicon Slot Waveguides

All-optical NOT, OR, and Exclusive OR(XOR) logic gates utilizing silicon slot waveguides are proposed and numerically analyzed in this work. The structure has a silicon slab with slot regions such as two input waveguides and square cavity resonators and one output waveguide. The optical spectra of the designed structures are attained with the method of finite difference time domain. The all-optical logic gate features of the design are achieved by applying optical signals with 00 or 1800 phase differences from the input ports. Basic parameters such as transmission spectrum (T), modulation depth (MD), and contrast ratio (CR) are performed to show the optical features and ability of the proposed logic gates. The threshold transmission limit is 1.7% to define the status of the output ports as ON or OFF. At 689.5 nm, the maximum transmission, modulation depth, and contrast ratio are 149%, 97%, and 15.36 dB, respectively.

Four-State Electrochromism in Tris(4-aminophenyl)amine- terephthalaldehyde-based Covalent Organic Framework.

Covalent organic frameworks (COFs) are of massive interest due to their potential application spanning diverse fields such as gas storage and separation, catalysis, drug delivery systems, sensing, and organic electronics. In view of their application-oriented quest, the field of electrochromism marked a significant stride with the reporting of the first electrochromic COF in 2019 [J. Am. Chem. Soc. 2019, 141, 19831-19838]. Since then, new and novel COF structures with electrochromic features (denoted as ecCOFs) have been searched continuously. Yet, only a handful of ecCOFs have been constructed to date. A closer look at these reports suggests that multielectrochromism (showing at least three redox color states) in a COF assembly has only been achieved once, manifested through three-state electrochromism [Angew. Chem. 2021, 133, 12606-1261]. Herein, we report four-state electrochromism in tris(4-aminophenyl)amine-terephthalaldehyde (TAPA-PDA)-based COF constructed through the metal-catalyst free Schiff base approach. The four-state (orange, pear, green, and cyan) electrochromism demonstrated by the TAPA-PDA ecCOF opens several futuristic avenues for ecCOF's end use in flip-flop logic gates, intelligent windows, decorative displays, and energy-saving devices.

A reverberating triple AND logic gate nanomachine for intracellular multi-enzyme tracking and MicroRNA detection

With the rapid advancement of molecular biology and nanotechnology, DNA logic gates have emerged as a method to simulate complex chemical reaction networks, which is crucial for distinguishing tumor cells from normal cells in early cancer diagnosis and treatment. The current challenges include the compositional differences in biomarkers between tumors and normal tissues and achieving high specific imaging in low-expression miRNAs within cells. We developed a triple AND logic-gate nanomachine that utilizes the high expression of matrix metalloproteinase (MMPs) in tumor metastasis and the specific overexpression of telomerase in cancer cells to initiate a first-stage signal and accurately identify tumor cells. This system then interacts with miRNA-21 to trigger a second-stage signal, enabling precise detection and signal amplification through the activity of purine-free/pyrimidine-free endonuclease 1 (APE1). This system can not only achieve efficient target recognition in complex bio-logical samples, but also provide a strong detection signal through continuous signal amplification, greatly improving the accuracy and reliability of diagnosis. This research provides a new molecular tool for cancer diagnosis, facilitating early detection and improving patient treatment outcomes and quality of life. Additionally, the principles and methods of this technique can be applied to the detection of other disease markers and tumor cell subtypes.

Chromogenic Chemosensor for Simultaneous Detection of PO4 3- and CO3 2- Anions in Organo-Aqueous Solutions: Application in Arduino Based Electronic Color Sensor Device and Logic Gate.

Three new chromogenic receptors have been synthesized with the primary objective of facilitating the selective recognition of PO4 3-and CO3 2- ions in an organo-aqueous medium. R1 and R2 exhibit an extraordinary detection limit aligning with both EPA and WHO guidelines. R1 shows LOD of 0.135 ppm for PO4 3- and 0.175 ppm for CO3 2-, while R2 sets forth a LOD of 0.427 ppm for PO4 3- and 0.729 ppm for CO3 2-. The binding mechanism involves intramolecular charge transfer (ICT) band are substantiated by comprehensive studies that include UV-Vis titration, 1H-NMR titration, DFT studies and electrochemical studies. Chemosensors were employed in the formulation of logic gate, the fabrication of a paper strip test kit and its application in RGB color sensor device.

Triphenylamine-Based Covalent Organic Framework Films for Dopamine-Responsive Electrofluorochromism.

Covalent organic framework (COF) film with electrofluorochromic (EFC) and electrochromic (EC) properties has been synthesized by using triphenylamine-based monomers. The film exhibited a high maximum fluorescence contrast of 151 when subjected to a drive voltage of 0.75 V vs the Ag/AgCl electrode, causing the fluorescence to be quenched, which resulted in the EFC process's "fluorescence off" state. The switching times for the fluorescence on and off states were 0.51 and 7.79 s, respectively. Over the same voltage range, the COF film also displayed EC properties, achieving a contrast of 50.23% and a coloration efficiency of 297.4 cm2 C-1 at 532 nm, with switching times of 18.6 s for coloration and 0.7 s for bleaching. Notably, the quenched fluorescence of the COF film could be restored by adding dopamine as a reductant. This phenomenon enabled the implementation of a NAND logic gate using the applied potential as a physical input and dopamine addition as a chemical input. This study demonstrates the successful development of COF films with bifunctional EFC and EC properties, showcasing their potential for use in constructing advanced optoelectronic devices.

Circularly Polarized Phosphorescence Energy Transfer Combined with Chirality‐Selective Absorption for Modulating Full‐Color and White Circularly Polarized Long Afterglow

AbstractCircularly polarized long afterglow (CPLA) attracts great interests in multi‐disciplinary fields with significant potentials in optical multiplexing applications, but achieving full‐color and white CPLA is still challenging. The present contribution reports the first success in utilizing circularly polarized phosphorescence energy transfer (CPP‐ET) combined with chirality‐selective absorption (CSA) to construct full‐color and white CPLA materials. Blue CPLA with luminescence dissymmetry factor (glum) of 3×10−2 is firstly obtained via the CSA effect of chiral helical polyacetylene and blue ultralong afterglow of inorganic phosphor BP. Significantly, full‐color and white CPLA films are prepared by simply blending different fluorophores into the blue‐CPLA films via CPP‐ET. Benefited from the persistent luminescence of BP, the lifetimes of the fluorophores increase from nanoseconds to minutes, and ultralong full‐color CPLA emissions lasting for more than 20 min are realized with glum of 10−3. Also noticeably, chiral optoelectronic devices, multi‐dimension information encryption and chiral logic gate are developed based on the full‐color tunable CPLA‐active materials. The established strategy provides a universal platform for future development of CPLA‐active materials with great applications.

Circularly Polarized Phosphorescence Energy Transfer Combined with Chirality-Selective Absorption for Modulating Full-Color and White Circularly Polarized Long Afterglow.

Circularly polarized long afterglow (CPLA) attracts great interests in multi-disciplinary fields with significant potentials in optical multiplexing applications, but achieving full-color and white CPLA is still challenging. The present contribution reports the first success in utilizing circularly polarized phosphorescence energy transfer (CPP-ET) combined with chirality-selective absorption (CSA) to construct full-color and white CPLA materials. Blue CPLA with luminescence dissymmetry factor (glum) of 3×10-2 is firstly obtained via the CSA effect of chiral helical polyacetylene and blue ultralong afterglow of inorganic phosphor BP. Significantly, full-color and white CPLA films are prepared by simply blending different fluorophores into the blue-CPLA films via CPP-ET. Benefited from the persistent luminescence of BP, the lifetimes of the fluorophores increase from nanoseconds to minutes, and ultralong full-color CPLA emissions lasting for more than 20 min are realized with glum of 10-3. Also noticeably, chiral optoelectronic devices, multi-dimension information encryption and chiral logic gate are developed based on the full-color tunable CPLA-active materials. The established strategy provides a universal platform for future development of CPLA-active materials with great applications.

Molecular Logic Gates Derived from Fluorescent Natural Products

Fluorescent natural products have been a source of fascination for centuries. In this review, we highlight natural products and natural product derivatives as optical logic-based molecules. The early beginnings of the field of molecular logic-based computation are introduced and followed with literature examples of logic gates from fluorescent natural products. The intention is to arouse the curiosity of readers to go out and discover more fluorescent natural products with intrinsic logic properties.

Tuning the Structures of Amide‐Imine Conjugates for Sequential Optical Recognition of Mo(VI) and AsO2− Ions

AbstractTwo amide‐imine conjugates where amide is synthesized by reacting hydrazine with 4‐hydroxybenzoic acid and subsequently condensed with 2‐hydroxy naphthalene‐1‐carbaldehyde (m1) and 2‐hydroxy benzaldehyde (m2), selectively detects Mo(VI) at nano molar level via change in emission characteristics. The interactions have been authenticated from single crystal X‐ray structures of resulting Mo(VI) complexes (Mo1 and Mo2). Further, Mo1 selectively interacts with AsO2− via formation of H‐bond that facilitates its detection through change of emission characteristics. The binding constant of Mo1 for AsO2− is 1.02×105 M−1/2. The TCSPC studies support the interaction of Mo1 with AsO2−. The probe‐analyte interaction has also been established by different spectroscopic techniques like 1H NMR, ESI‐MS, FTIR and Jobs experiment. Theoretical DFT studies justifies the reason behind the interaction and support experimental spectroscopic findings. Notably, the sequential fluorescence recognition of Mo(VI) and AsO2− by m1 have been explored to construct a logic gate.