<p indent=0mm>The science departments of National Natural Science Foundation of China (NSFC) carry out strategic research on discipline development every five years, and formulate discipline plans and several priority funding areas for the next five years. Then they successively release guidelines for Key Program and Major Program (K&M) projects to promote the development of priority funding areas. In order to understand the impacts of the discipline plan on discipline development, this study takes the discipline of management science and engineering during the 13th Five-Year Plan period as an example, and uses the approved K&M projects to represent the discipline plan, the General Programs, Young Scientists Fund, and Fund for Less Developed Regions (GY&L) projects to represent the individual thinking of general scholars, and the academic literature from representative international journals to represent the international frontiers and hot spots. This study uses the Latent Dirichlet Allocation (LDA) method, as well as high-frequency word analysis, and introduce a concept of fitting rate to analyze the relationship between NSFC projects during 2016 and 2020 and academic literatures during 2011 and 2020. The results show that NSFC projects have higher fitting rates with academic literature in the academic areas with more K&M projects funded than in those with fewer K&M projects funded, and the academic areas with higher fitting rates between K&M projects and academic literature usually have higher fitting rates between GY&L projects and academic literature. Furthermore, academic areas with higher fitting rates between NSFC projects and academic literature tend to have more projects of National Science Fund for Distinguished Young Scholars and Excellent Young Scientists funded. Therefore, NSFC’s discipline plan has a profound, extensive and long-term impact on the discipline development. The impact goes from top to bottom, from points spreading to areas. It does not only determine the current distribution of priority areas, but also affects the potential distribution of young scientists in the future. Because the development paths of sciences have similarities, the conclusions of this study could also be useful to other disciplines. We should fully understand and make use of these advantages of the discipline plan to promote the development of academic areas to meet national requirements, and aim at key fundamental fields to accumulate young talents in advance.