Discipline Construction Research Articles

Multiomic characterisation of the long-term sequelae of SARS survivors: a clinical observational study

We aimed to characterise the long-term health outcomes of survivors of severe acute respiratory syndrome (SARS) and determine their recovery status and possible immunological basis. We performed a clinical observational study on 14 health workers who survived SARS coronavirus infection between Apr 20, 2003 and Jun 6, 2003 in Haihe Hospital (Tianjin, China). Eighteen years after discharge, SARS survivors were interviewed using questionnaires on symptoms and quality of life, and received physical examination, laboratory tests, pulmonary function tests, arterial blood gas analysis, and chest imaging. Plasma samples were collected for metabolomic, proteomic, and single-cell transcriptomic analyses. The health outcomes were compared 18 and 12 years after discharge. Control individuals were also health workers from the same hospital but did not infect with SARS coronavirus. Fatigue was the most common symptom in SARS survivors 18 years after discharge, with osteoporosis and necrosis of the femoral head being the main sequelae. The respiratory function and hip function scores of the SARS survivors were significantly lower than those of the controls. Physical and social functioning at 18 years was improved compared to that after 12 years but still worse than the controls. Emotional and mental health were fully recovered. Lung lesions on CT scans remained consistent at 18 years, especially in the right upper lobe and left lower lobe lesions. Plasma multiomics analysis indicated an abnormal metabolism of amino acids and lipids, promoted host defense immune responses to bacteria and external stimuli, B-cell activation, and enhanced cytotoxicity of CD8+ T cells but impaired antigen presentation capacity of CD4+ T cells. Although health outcomes continued to improve, our study suggested that SARS survivors still suffered from physical fatigue, osteoporosis, and necrosis of the femoral head 18 years after discharge, possibly related to plasma metabolic disorders and immunological alterations. This study was funded by the Tianjin Haihe Hospital Science and Technology Fund (HHYY-202012) and Tianjin Key Medical Discipline (Specialty) Construction Project (TJYXZDXK-063B, TJYXZDXK-067C).

The status quo and development trend of talent cultivation in academic journal studies in China: A case study of Master's and Doctoral theses

Background: This paper aims to investigate the situation of discipline construction in the field of academic publishing in China, including the transfer of talents to the academic publishing and its impact on the research and development of the academic publishing in the future. Methods: This research conducted a comparative analysis of the quantity of Master’s and Doctoral theses on academic journal studies in terms of relevant educational institutes, disciplines, high-frequency keywords, and research hotspots. Result: It was found that the number of Master’s and Doctoral theses on academic journal studies has increased since 2004 and remained steady during 2016–2021; among the 26 research institutes in which more than 10 Master’s and Doctoral theses in this field were published, information science, library science, communication, and journalism constituted the main disciplines of academic journal studies in China, and the theses published in these disciplines accounted for 34.4% of the total. The research hotspots included open access, editing and publishing, bibliometrics, etc. until 2015, and bibliometric analysis from 2016–2021. With bibliometric analysis, in the past ten and more years, 849 excellent graduates have been engaged in the academic journal studies. Some research institutes have made significant contributions to this field, cultivated a great number of talents, and introduced them to this field, promoting the development of the academic publishing. Conclusion: The number of Master’s and Doctoral theses focusing on academic journal studies has grown rapidly, leading to a picture of diversified prosperity in schools, majors, and fields of study. Universities and research institutes in China should establish a special research direction of academic journal studies to give impetus to the academic publishing industry.

Identification and functional characterization of a novel truncating splicing variant in COL4A5 gene causes X-linked Alport syndrome with astigmatism.

Identification and functional characterization of a novel truncating splicing variant in COL4A5 gene causes X-linked Alport syndrome with astigmatism.

Innovation management framework for achieving sustainability through managing risks of innovative solutions during the design process

Purpose This paper aims to develop an innovation management framework for achieving sustainability by managing risks associated with innovative solutions during the design process. Design/methodology/approach To achieve the abovementioned aim, a research methodology was designed to achieve four objectives. Firstly, a literature review was conducted to investigate the concepts of sustainability, innovation, innovation management and innovation and the design process. Secondly, three case studies were selected and analysed to validate the identified risks of innovation and to investigate the role of innovation management towards managing risks of innovation during the design process. Thirdly, a survey questionnaire was carried out with a representative sample of architectural design firms (ADFs) in Egypt to examine their perception and application of innovation management as an approach to managing risks of innovative solutions during the design process. Finally, developing an innovation management framework to achieve sustainability through managing risks associated with innovative solutions during the design process. Findings The literature review revealed that innovation plays a significant role towards achieving sustainability objectives, but integrating innovative solutions during the design process is frequently associated with risks. During the course of this research, 30 risks of innovation were identified and classified into four categories of product, process, person and press. Case studies showed that ADFs that applied innovation management approaches were successful in managing the risks associated with innovative solutions, whereas others that failed to use such approaches failed to meet sustainability objectives. Results of the survey questionnaire revealed that ADFs not only recognised the importance of innovative solutions in developing sustainable projects but also showed a gap between theory and practice. “Project delivery” is the most important type of innovation for ADFs in Egypt, followed by “building technologies” and “organisational culture”. Moreover, there is a misalignment between ADFs’ perceptions and the strategies used to deliver successful innovations. The highest risks of innovation are “unanticipated cost of innovation”, “manufacturing technologies and development issues” and “failing to meet technical criteria”. Research limitations/implications Because of the conceptual nature of the developed framework, it has to be tested and validated to ensure its capability to achieve sustainability through managing the risks of innovative solutions during the design process which, in this research, adopted the Royal Institute of British Architects plan of work stages. Moreover, the lack of data availability directed this study to present and analyse only three case studies. Practical implications This research presents a practical solution to achieve sustainability through managing risks of innovation during the design process. It is a structured tool that can be used by ADFs in Egypt towards facilitating the shift in the direction of a more economically viable, environmentally friendly and socially acceptable built environment. Originality/value Although innovative design solutions are needed in developing sustainable buildings, a practical and systematic framework to manage associated risks during the design process is still lacking. In addition, current studies are business-oriented and need to be reinterpreted to fit with the architectural, engineering and construction disciplines. Thus, this research developed an innovation management framework to achieve sustainability through managing the risks associated with innovative solutions during the design process, which represents a synthesis that is novel and creative in thought and adds value to the knowledge in a manner that has not been previously explored.

Incidence of thymic malignancies in China: A longitudinal study based on a national commercial claims database from 2007 to 2016.

Incidence of thymic malignancies in China: A longitudinal study based on a national commercial claims database from 2007 to 2016.

Functions and Strategies of University Journals in Discipline Construction

There is a win-win relationship of synergism and benign interaction between university journals and discipline construction, which plays an important role in showcasing innovative achievements, promoting talent training and leading discipline development. It is necessary to actively enhance the participation of journals in discipline construction, explore ways to focus on the development direction of key disciplines, give full play to the academic orientation of editorial board, and gather discipline achievements and talents to help discipline construction and development.

Research on Teacher Ability Improvement in Higher Vocational Colleges under the background of new engineering

The new engineering construction is a major strategic choice of higher education reform and innovation. In order to comprehensively promote the construction and reform of new engineering, the improvement of teachers’ core competence is the key. Teachers are the main force in the construction of new engineering. Both discipline construction and talent innovation training need a group of high-level teachers with excellent informatization vocational ability, strong ideological and political ability, high innovation and entrepreneurship ability, and strong teaching and research ability. Based on the construction of new engineering, this paper expounds the ability of teachers in higher vocational colleges and the significance of improving teachers. Through the analysis of the practical problems facing the ability improvement, explore the path of ability improvement, and promote the high-quality development of vocational education.

Retracted: Discipline Construction and Development of Medical Universities in Complex Environment under Digital Technology and Structural Equation Model.

[This retracts the article DOI: 10.1155/2022/6567625.].

Theoretical Construction of Educational Leadership Discipline from the Perspective of Research Based Learning

Theoretical Construction of Educational Leadership Discipline from the Perspective of Research Based Learning

Blended Teaching of Translation: Problems and Suggestions

Blended teaching is prevailing among universities. This teaching mode can improve translation training effectiveness and facilitate the construction of translation discipline. However, the problems in blended teaching are becoming increasingly prominent. As far as the blended teaching mode is concerned, there are some general problems such as inaccurate cognition of the concept of "blending", low degree of online and offline integration and teacher-centered instead of student-centered learning. As far as translation discipline is concerned, lack of translation technology resources and insufficient application of them are prominent. In response to these problems, this paper puts forward suggestions: to clarify the concept of "blended teaching"; to build an online teaching platform; to improve the management and evaluation system related to blended teaching.

К ВОПРОСУ ОБ УПРАВЛЕНИИ ЧЕЛОВЕЧЕСКИМИ РЕСУРСАМИ С ПРИМЕНЕНИЕМ ТЕХНОЛОГИЧЕСКОГО ИНСТРУМЕНТАРИЯ

Nowadays UAV technology is increasingly used as a tool for student education and research. This paper discusses the main aspects of the use of UAVs for educational purposes, including science, engineering, construction, agriculture and other disciplines. Practical aspects of teaching UAVs in the educational process were mentioned, including teaching students to pilot drones, developing programs and courses, as well as research projects based on the use of UAVs. These advantages and challenges that arise in the course of existing problems in the field of medical equipment during the implementation of technologies are analyzed, as well as an analysis of the prospects for the development of this area in the education sphere in Russia. The study provides an overview of the current state of UAV use in education and identifies the potential for further development of this technology in education.

Intelligent Manufacturing Management for New Business Discipline Construction: Exploring and Practicing the Path

Intelligent Manufacturing Management for New Business Discipline Construction: Exploring and Practicing the Path

Research on the development course of comparative pedagogy discipline construction in China

Research on the development course of comparative pedagogy discipline construction in China

Theory of creating new disciplines of safety and security (SS) science and essentials of 40 practical examples

The development of society and the demand for the improved safety and security (SS) of people in the SS research field have been constantly changing and growing, resulting in the emergence of new SS science disciplines. In this study, the conditions, academic thought, methodology, paradigm, and modes for creating new disciplines of SS science based on the practice experiences of creating new disciplines of SS science by the authors and methods of analysis and induction over the past ten years are summarized. Essentials of 40 new disciplines of SS science created are presented. The afore mentioned theoretical analysis can encourage the development of more new disciplines of SS science and shorten the incubation and growth cycle of new disciplines of SS science. Furthermore, the research results enrich the discipline construction theory of SS science and are crucial in promoting the development of SS science in the future.

Teaching and thinking on the use of digital media in stage design course under the background of first-class major construction

To face the global trend of digitalization and artificial intelligence, the School of Film-Video-Animation of Sichuan Fine Arts Institute has established the development of digitalization as the key field of the discipline construction of drama, film and television science and the national first-class major construction of drama, film, and television art design in the construction of "double world-class". The course of stage design starts from the perspective of spanning drama space and digital media to explore the cultural context of "large visual space field", as well as the interaction between different drama scenes and real-life art. By taking advantage of the integration of digital technology and traditional art, it constantly explores the "large perspective" under the "minor major of stage design". Since 2006, the course of stage design of drama, Film and Television Art Design Major of Film-Video-Animation School of Sichuan Fine Arts Institute has been conducting digital teaching reform and research. This paper will take the red drama "Democratic Course" as an example to analyze and study the case study of digital stage design course. This paper analyzes many problems in the application of digital media during red drama stage design from the perspective of discipline and profession, to provide reference for teachers and students at relevant universities, cross-media creators, and stage art practitioners.

Developing Ecological Agricultural Engineering to Promote Rural Revitalization in China

Ecological agricultural engineering is a necessary innovation and expansion of China’s agricultural engineering science and technology that aims to meet the overall, the whole chain and the coordinated development needs of the whole system for rural revitalization. Focusing on ecological agricultural engineering, this paper introduces its development and early practice and technology, and also discusses its development direction, development path, and important role in boosting rural revitalization. The development of ecological agricultural engineering will play an important role in China’s agricultural production practice, agricultural engineering discipline construction and agricultural and rural modernization.

Retracted: Evaluating and Exploring the Effectiveness of Journalism and Communication Discipline Construction in the Context of Smart Era

Retracted: Evaluating and Exploring the Effectiveness of Journalism and Communication Discipline Construction in the Context of Smart Era

First-Class Nursing Discipline Construction Spearheads the Cultivation of First-Class Talents

Cultivating first-class talents is a key task of the Double First-Class Initiative, a national plan to build a number of world-class universities and disciplines in China by the end of 2050. On the basis of reviewing the history of the development of the nursing discipline, we analyzed, herein, opportunities and challenges of nursing professional training under the strategic guidance of the Double First-Class Initiative. We proposed suggestions on the cultivation of first-class nursing professionals of the future by considering the following aspects, constructing a theoretical system of ideological and political education for nursing education with Chinese characteristics, exploring for ways to develop a nursing knowledge system and personnel training model around the axis of a life-course approach to health, building "nursing plus" interdisciplinary clusters to cultivate innovative talents with interdisciplinary integrated abilities, enhancing efforts to recruit and cultivate scientific and technological talents, optimizing in an all-round way the composition of qualified nursing personnel, gaining the support of first-class research platforms, and creating incubation centers for innovative and outstanding nursing professionals.

旅游发展对城市生态文明建设的影响及空间溢出效应——基于我国284个地级及以上城市的实证研究

PDF HTML阅读 XML下载 导出引用 引用提醒 旅游发展对城市生态文明建设的影响及空间溢出效应——基于我国284个地级及以上城市的实证研究 DOI: 10.5846/stxb202203280756 作者: 作者单位: 作者简介: 通讯作者: 中图分类号: 基金项目: 国家社会科学基金（21BGL149）；湖南省国内一流培育学科建设项目（5010002） Impact of tourism development on the construction of urban ecological civilization and its spatial spillover effect: An empirical study on 284 prefecture level and above cities in China Author: Affiliation: Fund Project: The National Social Science Fund of China；Domestic first-class cultivation discipline construction project in Hunan Province 摘要 | 图/表 | 访问统计 | 参考文献 | 相似文献 | 引证文献 | 资源附件 | 文章评论 摘要:生态文明建设是实现"美丽中国"的必由之路，旅游因其"绿色"属性与之联系十分密切，论证旅游发展能否促进生态文明建设并探究其空间溢出特征具有重要意义。在构建旅游发展对城市生态文明建设影响及空间溢出效应理论框架的基础上，通过熵权TOPSIS法对全国284个地级及以上城市2004-2019年生态文明建设水平（ECC）进行测度，使用空间杜宾模型揭示旅游发展对城市生态文明建设的影响及空间溢出效应。结果表明：①各城市ECC均取得不同程度提升，相对高值区集中于长江和黄河经济带下游沿线，低值区多分布在中西部地区；区域尺度下，各地区ECC长期呈"东-中-西"递减格局，内部发展差异性与其存在明显空间错位。②旅游发展能够显著促进"本地"和"邻地"城市生态文明建设，具体表现为"三轮驱动"下的水平提升，其对城市经济系统的驱动力显著大于生态和社会系统。③东、中、西部地区旅游发展对城市生态文明建设的影响和空间溢出效应均得到释放，空间异质性下二者作用强度与城市ECC基本"区域重叠"。④政策制定上，一方面在长期落实旅游业"生态优先"原则的基础上，加快旅游数字化建设和文旅融合步伐，充分释放其对生态文明建设的产业外部性；另一方面需加强旅游专项转移支付力度、构建东西部旅游开发对口帮扶机制，激发西部地区旅游内生动力。 Abstract:Construction of ecological civilization is one way to realize "beautiful China". Tourism is closely related to it because of its green attribute. It is of great significance to demonstrate whether tourism development can promote the construction of ecological civilization and explore its spatial spillover characteristics. This paper built a theoretical framework of the impact of tourism development on urban ecological civilization construction and spatial spillover effects. The ecological civilization construction level (ECC) of 284 prefecture level and above cities in China from 2004 to 2019 was measured by entropy weight TOPSIS method; The spatial Doberman model is used to reveal the impact of tourism development on the construction of urban ecological civilization and spatial spillover effect. The results show that:(1) the ECC of each city has improved to varying degrees, the relatively high value areas were concentrated along the lower reaches of the Yangtze River and the Yellow River economic belt, and the low value areas were mostly distributed in the central and western regions; On the regional scale, ECC in each region has been in a decreasing pattern of east-middle-west for a long time, and there is an obviously spatial dislocation between the internal differences of regional ECC and the development level of ECC among various regions. (2)Tourism development can significantly promote the construction of ecological civilization in local and adjacent cities, which is embodied in the improvement of the level under the "three wheel drive", and its driving force on the urban economic system is significantly greater than that of the ecological and social system. (3) The impact of tourism development on urban ecological civilization construction and spatial spillover effect in the east, middle and west regions have been released. Under the spatial heterogeneity, the intensity of the two effects basically overlaps with the urban ECC. (4) In terms of policy development, In order to bring into play the industrial externalities of tourism for the construction of ecological civilization, local governments should actively promote the digitalization of tourism and the integration of tourism and cultural industries, based on the principle of "ecological priority" in the long term; on the other hand, Chinese Government need to strengthen the transfer of special funds for tourism and establish a mechanism to support tourism between the eastern and western cities in order to achieve the development of tourism in the western region. 参考文献 相似文献 引证文献

Enhancing the Literature Guarantee Ability in the Discipline Construction of Local Ethnic Undergraduate Colleges and Universities

Enhancing the Literature Guarantee Ability in the Discipline Construction of Local Ethnic Undergraduate Colleges and Universities