Abstract The isovector part of the Dirac optical potential for nucleon-nucleus scattering is calculated using a folding model approach based on the relativistic nucleon-nucleon t-matrix. Exchange and Pauli blocking effects are taken into account. The calculated potentials are compared with those obtained in the impulse approximation. We use these potentials in a relativistic DWBA calculation of the amplitude for charge exchange (p, n) reactions leading to the isobaric analog states. Good agreement is obtained with the cross section and analyzing power data for reactions on 48Ca, 90Zr, and 208Pb nuclei. We also present calculations for the spin rotation parameter.