A passively Q-switched mode-locked all-solid-state Tm:CaYAIO4 (Tm:CYA) laser with a MoS2 saturable absorber is demonstrated for the first time. Employing a typical X-type cavity and output coupling mirror of 9%, when the laser diode (LD) pump power is higher than 8.5W, the laser enters into a stable Q-switched mode-locked operation, further increasing the pump power into a dual-wavelength operating state, the corresponding typical center wavelengths are 1863nm and 1877nm. When the pump power reaches 20W, the maximum output power is 1.15W, the frequency of mode-locked pulse is 103.7MHz, and the modulation depth of mode-locked pulses in the Q envelope is close to 100%. The results prove that MoS2 SA is suitable for 2 μm high power mode locking.