Dinner Table Research Articles

Prophylactic use of metformin in patients on alpelisib treatment.

e13040 Background: Alpelisib-induced hyperglycemia (HG) is the most common adverse event leading to interruption, reduction or withdrawal of the treatment. HG is an on-target effect that depends on the baseline metabolic status of the patient. In SOLAR-1 90,6% patients with high-risk at baseline HG G3/G4 was reported. Prophylactic use of metformin may prevent HG in patients at risk. Methods: HR+ HER2-negative advanced breast cancer patients were stratified to low-, moderate- or high-risk groups of HG based on the algorithm published in [1] before starting alpelisib 300 mg + fulvestrant (Alp + Fulv). Moderate- and high-risk patients used prophylactic metformin at 500-1000 mg or 2000 mg BID with breakfast and dinner (Table). Metformin was started at least one-week prior Alp administration. Fasting plasma glucose (FPG) was monitored qw and bw in low- and moderate-risk patients, and daily with home glucometer in addition to bw FPG for high-risk patients. The primary endpoint of retrospective analysis was to assess the incidence of HG G3/G4 in different risk groups based on CTCAE V4.03 guidelines. Results: A cohort of 18 patients (median lines of previous treatment in advanced disease was five, all patients has received CDK4/6 inhibitors) treated with Alp+Fulv in the Loginov Moscow Clinical Scientific Centerin 2020-2021 included 7 low-, 3 moderate- and 8 high-risk patients. Any grade HG was reported in 13 out of 18 pts; no cases of HG G2 or G4 were detected. HG G3 was reported in 5 out of 18 patients including in 2 out of 3 moderate-risk patients, and in 3 out of 8 high-risk patients. Anti-HG drugs used included metformin (6/18); empagliflozin (4/18), and linagliptin (1/18); 1 patient required Alp dose reduction to 250 mg due to HG G3; none discontinued Alp due to AEs. Other AEs included rash (7/18; no grade 4; grade 3 in 4/18), and blood creatinine increase (8/18 – all grade 1-2).The median PFS on treatment with Alp+Fulv was 7 months. Conclusions: Prophylactic use of metformin in patients with high risk of hyperglycemia could markedly reduce frequency and severity of hyperglycemia on alpelisib.[Table: see text]

Pelatihan Table Manners Mahasiswa Politeknik Darussalam

The purpose of this training is to provide valuable experience as well as useful knowledge for Darussalam Polytechnic students. The table manners activity is the main provision for students when they have finished studying at the Darussalam Polytechnic. The participants of this training were 108 students from all majors in Darussalam Polytechnic. This training was held at Fave Hotel Palembang on March 31, 2022. The speakers in this training were lecturers from the Travel Business Department who were competent in the field of hospitality and tourism. In this training, it is emphasized how to use good etiquette in eating. Eating etiquette which is manners at banquets. Dining etiquette at the dining table is quite simple, but there are some things that can be learned in how to sit up straight and don't lean on the back of the chair, and don't put your elbows on the dining table and use a napkin on your lap. Banquets are not just how to put food in the mouth, but are related to certain eating etiquette that can show a person's personality. Manners at the dinner table really need to be learned by Darussalam Polytechnic students so that they can have skills in good eating procedures at the dinner table, starting with how to proceed at the dinner table by doing table manners training.

Edith Wharton in France

Edith Wharton in France

Red Meat Republic: A Hoof-to-Table History of How Beef Changed America

Red Meat Republic: A Hoof-to-Table History of How Beef Changed America

Some Versions of Pastoral and Related Writings

Some Versions of Pastoral and Related Writings

From Medieval Romance to Contemporary Opera: Philosophy, Allegory, Eros

From Medieval Romance to Contemporary Opera: Philosophy, Allegory, Eros

“O My Mother”: Mormon Fundamentalist Mothers in Heaven and Women's Authority

“O My Mother”: Mormon Fundamentalist Mothers in Heaven and Women's Authority

Wonder Woman

Wonder Woman Constance Adler (bio) There is a scar in the center of my chest. A whitish and shiny round patch, the size of a silver dollar, the scar does not match the surrounding skin. It does not blend with its environment; it cannot not hide. Located just above what we might generously refer to as my "cleavage," this scar marks the place where a hard pad pressed into my skin for the months that I wore a back brace, known as the Milwaukee brace, when I was fourteen years old. Here is a picture of the brace: Imagine a contraption that clasped my head in a metal loop, secured tight against my chin and the back of my skull. Metal posts connected the head restraint to a hard, plastic girdle that encased my pelvis and was locked shut at the back with straps, so tight that it left deep-red indentations in the soft flesh of my backside. Once in place, the whole thing resembled a medieval instrument of torture. I came to think of it as a cage that I carried around with me all the time. It was hideous, and it made me hideous. While I was in the brace, it was impossible for me to move from hips to head. The cage held me in a rock-rigid grasp. I could not sleep curled up in a protective knot, as was my habit, but had to lie on my back like a corpse on a slab. I could not bend or turn side to side or look up or down. I could walk, but it was difficult to eat or talk because my chin kept hitting the metal loop around my head when I opened my mouth. I could not tip [End Page 111] my head to look down to the food on the plate in front of me and had to guess at what I might be forking into my mouth. I could go to school, and spend time with my friends, but I was always caged. I had to wear extra-large clothes to fit over the brace, and its hard unsightly lumps protruded through my clothes instead of the normal soft form of my girl's body. I could not see my own feet or reach down to tie my own shoelaces. If my shoe came untied at school, I had to ask a friend to tie it for me. Some kids asked if I'd been mangled in a car accident. The clinical purpose of the Milwaukee brace was to maintain my girl's body in this unyielding position for a year until my back and shoulders grew accustomed to a center plumb line. Then I'd be released, ideally as a more perfect girl. One day I'll have to find out why Milwaukee gets credit for this instrument of torture. What I can tell you now is that my parents put me into this brace for reasons that were a complete mystery to me. They had threatened me with a back brace if I didn't stand up straight, a threat that I did not take seriously. At the dinner table, my father enforced the posture requirement by hitting the back of my head. Slouching made me ugly, apparently, or less than perfect, which for a girl was a moral stain. But I wasn't paying much attention to threats or perfection. I was a dreamy, distracted child with other things on my mind, far more interesting than my posture. This private realm of my imagination also offered an escape from beatings, so I went there often. When I failed to be mindful of my posture, my parents followed through on the threat. My mother and father presented this back brace to me as a punishment for my willful disobedience. This sounds crazy, I know. Why would anyone do that to their kid just to win a power game? But that was thrust of their argument at the time. My mother was in charge of bringing me to the DuPont Orthopedic Clinic in Delaware. During the course of fitting me for the brace, one of the doctors took photographs of...

The reflective eater: Socializing French children to eating fruits and vegetables

Studies often suggest that the family meal is the locus for the acquisition of healthy eating habits. However, these studies rarely offer a deeper understanding of what it is about eating together as a family that increases the intake of healthy foods, such as fruits and vegetables. This ethnographic study examines dinners in French households, whose children have shown to habitually consume fruits and vegetables, analyzing talk around the dinner table. Our analysis shows that naturally occurring exchanges between parents and children socialize children to experiencing eating in culturally informed ways that promote attending to the prized characteristics, such as origin, quality, taste, and preparation of food items that intrinsically elevates their value and leads to their consumption. These communicative patterns also encourage reflection and openness to foods, which, we posit, constitute ways of ‘doing being French’. Ultimately, we argue that French children's readiness to eat fruits and vegetables is not linked to them being healthy, but rather is derived from the cultural significance of experiencing sensory pleasure from food and from being able to talk about and share these experiences with others, that is being reflective eaters.

Travelling Noodles and Migrating Pieces of Raw Fish

Travelling Noodles and Migrating Pieces of Raw Fish

Politics at the Dinner Table: Thanksgiving and Family Influences on Political Opinions

Politics at the Dinner Table: Thanksgiving and Family Influences on Political Opinions

Epicurus at Plutarch’s dinner table: a tale of after-dinner sex and questionable polemics (Quaest. conv. III, 6)

The present article deals with the sixth quaestio of Book III in Plutarch’s Quaestiones convivales, which revolves around Epicurus’ claim that it is physically harmful to have sexual intercourse after dinner. After an appraisal of the Epicurean dictum itself, I argue that Plutarch’s final interlocutor, Soclarus, incorporates several polemical anti-Epicurean arguments into his speech, which can also be found elsewhere in Plutarch’s anti-Epicurean writings. Ultimately, I try to establish to what extent Soclarus’ response to Epicurus’ theory conforms to the exigencies of intellectual honesty.

Pester power- The most powerful weapon of kids

The internets have taken up the majority of children's leisure time, drastically altering their media habits. Even the dinner table, where parents used to instill many positive values and wholesome ideas in their children, has been supplanted with watching television. Children today are so technologically aware that they practically know how everything works on the internet, and their browsing habits expose them to more of these sites and products around the world that they may then demand from their parents. Children's growing consumerism is blamed for the emergence of Pester Power. Due to the deluge of new TV (television) content, this trend has emerged. Nowadays, almost all marketers seek to promote their goods directly to the young target audience. The composition of Indian families has shifted from joint families to nuclear or extended families as a result of influences from the west. Indian consumerism has been greatly influenced by exposure to the globalised world and changing family dynamics. Kids are ruling the consumer market as three distinct segments are represented by them. The research aims to study the influence of cartoon character, celebrity endorsement on child’ pester power. The study also proves that there is positive relationship between humour in advertisements with child buying behaviour.

In Memoriam

In Memoriam Verlyn Flieger Priscilla Tolkien, 1929–2022 Priscilla Tolkien died on Monday, February 28, 2022. She was ninety-two years old and had lived most of her life in the bright spotlight of her father's work. She was ambassador at large to the myriad readers for whom she represented their most direct contact with his genius. In countless appearances at conferences and in interviews she shared her personal experiences of both the man and his work. In 1992 Priscilla and her older brother John published The Tolkien Family Album, a collection of family photographs with commentary, inviting Tolkien's readers into his and his family's domestic life. Only they could have done it, and the book remains the first and most genuine introduction to Tolkien as his family knew him. This essay will be a remembrance of Priscilla Tolkien as I knew her—a warm, witty, razor-sharp lady who carved out her own career independent of her father's fame, first as a social worker and probation officer, and then for many years as a teacher. I met her first in 1980 when, learning she was scheduled to give a talk at my local public library, I was emboldened to call the house where she was visiting and ask if she might be willing also to come and talk to my Tolkien class, at that time deep in The Lord of the Rings. She refused, politely but firmly, and I realized she must get such requests all too often. She did, however, take time to chat after her library talk, and so remembered me when I wrote a year later to say I was coming to England and would like to meet. That visit began a friendship that lasted forty years, during which time we both crossed and recrossed the Atlantic many times to visit one another. I treasure the memories. I remember her best in Oxford, pouring tea or serving dinner in her tiny but warmly welcoming house on Middle Way in Summertown. I remember its wall of windows facing the sun, its front room bookshelf overflowing with volumes of her father's works, the adjacent wall holding her mother's piano. I remember her beautiful garden behind the house, a long narrow space crammed with flowers but with a path to the blossoming apple (or was it crabapple?) tree, the statue of St. Joseph holding the baby Jesus. The sun seemed always to be shining. I remember walking with her down to South Parade, the beginning of the Summertown shopping district, and having her stop again and again to say hello to street people, vendors, buskers, panhandlers. They all knew her, and she knew them. Her hand was always reaching for her purse to find coins. I remember her visits to my home, wonderful, wide-ranging talks [End Page 3] around the dinner table on everything from problems of theology to the vagaries of social work. I remember the part she read in an Arthurian playlet I had written, the sultry, provocative Morgause whom she clearly enjoyed bringing to life. I remember the time she attended (incognito) a talk on Tolkien I gave at the Smithsonian in downtown Washington, and her amusement at the range of questions I was getting from the audience about the Tolkien family, especially at the one about "the daughter." In her later years, when travel became difficult, we talked often on the phone. It was when she didn't answer the last time I called, and my voice message went unreturned, that I knew something was wrong. I called Cathleen Blackburn, the Estate lawyer and her friend for many years, who told me the situation was grave. Thanks to Cathleen, I was able to send Priscilla a last message and to be assured that she got it before she died. She's a grand memory, one that I will always treasure—not because she was a Tolkien, but because she was Priscilla. ________ Tolkien Studies notes with sadness the passing of Edmund R. Meskys (1936–2021), who died on July 25, 2021, at the age of 85. Born in New York City of parents from Lithuania, Ed was educated...

ГАСТРОДИПЛОМАТИЧНІ КАМПАНІЇ ЯК ІНСТРУМЕНТИ БРЕНДИНГУ КРАЇН НА МІЖНАРОДНОМУ РІВНІ

The article deals with the research of gastrodiplomacy campaigns as instruments for branding countries at the international level. The image of any country in the modern system of international relations depends not only on political, economic, military resources, but also on its ability to present itself through culture. That is why public or people's diplomacy is becoming more and more important in foreign policy, in which not only professional diplomats but also representatives of public organizations, business circles, science and education, culture and art, mass media, etc. take an active part. It is emphasized that in recent years a new direction of diplomacy has begun to develop – gastrodiplomacy. It has become an instrument of intercultural relations and relies on the resources of national cuisines. It is used at the dinner table to influence the thoughts and moods of politicians and world leaders, as well as ordinary citizens. Over the past two decades, many countries have successfully conducted gastrodiplomacy campaigns to increase their cultural influence abroad. The article analyzes the gastrodiplomacy campaigns of such countries as Thailand, Japan, Malaysia, Peru, South Korea and Taiwan. These countries were among the first to use gastrodiplomacy as a tool for branding their countries at the international level. It has been established that gastrodiplomacy should not be equated with ordinary advertising campaigns to promote various national food products, as its purpose and objectives are much broader. It is aimed at forming a positive brand of the country in the world by promoting national cuisine, stimulating foreign trade and tourism, improving the investment climate, attracting more investors, increasing the competitiveness of the economy.

An Uninvited Seat at the Dinner Table: How Apicomplexan Parasites Scavenge Nutrients from the Host.

Obligate intracellular parasites have evolved a remarkable assortment of strategies to scavenge nutrients from the host cells they parasitize. Most apicomplexans form a parasitophorous vacuole (PV) within the invaded cell, a replicative niche within which they survive and multiply. As well as providing a physical barrier against host cell defense mechanisms, the PV membrane (PVM) is also an important site of nutrient uptake that is essential for the parasites to sustain their metabolism. This means nutrients in the extracellular milieu are separated from parasite metabolic machinery by three different membranes, the host plasma membrane, the PVM, and the parasite plasma membrane (PPM). In order to facilitate nutrient transport from the extracellular environment into the parasite itself, transporters on the host cell membrane of invaded cells can be modified by secreted and exported parasite proteins to maximize uptake of key substrates to meet their metabolic demand. To overcome the second barrier, the PVM, apicomplexan parasites secrete proteins contained in the dense granules that remodel the vacuole and make the membrane permissive to important nutrients. This bulk flow of host nutrients is followed by a more selective uptake of substrates at the PPM that is operated by specific transporters of this third barrier. In this review, we recapitulate and compare the strategies developed by Apicomplexa to scavenge nutrients from their hosts, with particular emphasis on transporters at the parasite plasma membrane and vacuolar solute transporters on the parasite intracellular digestive organelle.

Reasoning Talk at Chinese Families' Dinner Table: Across Three Generations and Different Communicative Contexts.

This study examines the feature of reasoning talk used by 37 Chinese families at the dinner table across three generations with the background of co-parenting and in consideration of different communicative contexts. Drawing upon Hasan’s semantic framework, reasons were mainly coded as logical or social types. We categorize the communicative context of reasoning talk into contextualized (meal-related) and decontextualized topics. When the proportion of social reasoning was found slightly higher than that of logical reasoning, the families’ reasoning talk account for only 3.85% of the total language. Specifically, the count of mothers’ total reasoning talk was significantly above other family members, while there were no significant differences among the other participants. The effect of the communicative contexts on family members’ social reasoning was found. The reasoning talk grounded on local rules (family-made rules) and coercive power occurred significantly more frequently in contextualized than decontextualized context. A higher rate of local-rule grounded reasoning talk of all family members appeared in contextualized than decontextualized context, and this gap was particularly obvious among mothers. These findings reveal the significant role of mothers in family communications and confirm the pedagogical values of decontextualized communicative context for promoting children’s learning opportunities at the dinner table.

In Memoriam: Joe Kamiya, 1926–2021

In Memoriam: Joe Kamiya, 1926–2021

Books and Manuscripts 2020

Books and Manuscripts 2020

Understanding food selection and dieting patterns: type 2 diabetes mellitus patients and their families

Background. The prevalence of type 2 diabetes mellitus (T2DM) is increasing from year to year, especially in Indonesia. The risk of T2DM starts at the dinner table in the family. Meal planning plays an important role in reducing the potential complications associated with poor glycemic, lipid and blood pressure control. Focusing on reducing sugar, fat and sodium intake and incorporating culture-appropriate foods will improve adherence. However, T2DM patients develop conflicting eating disorders in which there is a gap between nutrition and self-fulfillment regarding eating control. The purpose of this research is to explore the understanding of the diabetes patient and their family in determining the selection of food and eating pattern during the disease. Materials and methods. This study explores the understanding of T2DM patients and their families in the Depok and Jakarta. The purposive sampling method used 14 participants and 7 family members. The data obtained from participant observation and in-depth interviews then analyzed using thematic analysis. Using a descriptive phenomenological method with a semi structured in-depth interview. The interviews were conducted face to face from October 2017— July 2018 and were analyzed by thematic analysis Collaizi’s method. Results. This study found 4 important themes: 1) food is believed to affect high blood sugar; 2) changes in diet after diabetes; 3) the main concern of the family is to keep eating but not make it a burden; and 4) the challenge faced by participants and their families is the lack of information. This study recommends continuing education and partnerships from nurses about the importance of the relationship between diet and blood glucose levels. Conclusions. People are inclined to rely on simple strategies that limit search when making food choices. The ability of patients and families regarding food ingredients to maintain blood sugar stability is the concern of nurses in providing nutritional education. Food labels can (and to some extent do) provide a wide variety of desirable information, ranging from food content to production details, the food’s carbon footprint, and its origins.