We present a coherent model that combines jet production from perturbative QCD with strongly-coupled jet-medium interactions described in holography. We use this model to study the modification of an ensemble of jets upon propagation through a quark-gluon plasma resembling central heavy ion collisions. Here the modification of the dijet asymmetry depends strongly on the subleading jet width, which can therefore be an important observable for studying jet-medium interactions. We furthermore show that the modification of the shape of the leading jet is relatively insensitive to the dijet asymmetry, whereas the subleading jet shape modification is much larger for more imbalanced dijets. Finally, we compare the results of our holographic model to a recent CMS measurement.