Abstract Background The robotic approach has gained interest in oncologic colorectal surgery. In Crohn’s disease (CD) patients presenting with marked mesenteric inflammation and bowel fragility, very little safety data have been reported (1, 2). The lack of haptic feedback and the restricted surgical field are potential disadvantages of the robotic approach that could lead to a higher risk of intraoperative incidents compared to laparoscopy. Methods A total of 259 patients undergoing minimally invasive ileocolic resection (ICR) for CD (66 robotic and 193 laparoscopic) were included in 3 tertiary IBD centers. Intraoperative incidents were defined as unintended gastrointestinal opening and hemorrhage and conversion. Intraoperative and postoperative outcomes of robotic and laparoscopic approaches were compared after propensity-score matching including CD severity. Results After matching, 66 robotic patients were compared to 66 patients who underwent laparoscopic surgery. CD was defined as complex (i.e. abscess, fistula or inflammatory mass) in most patients in the robotic and laparoscopic groups (71% vs 70%, NS). Ileocolic resection was performed as an iterative procedure in a few patients in both groups (7.6% vs 6.1%, NS), and the main indication for surgery was a symptomatic digestive fistula (50% vs 58%, NS). A primary anastomosis was performed in almost all patients (97% vs 92%, NS). No statistically significant difference was observed between the robotic and laparoscopic groups regarding the rates of intraoperative incidents (15% vs 12%, NS), conversion (12% vs 9%, NS), overall morbidity (36% vs 29%, NS), or intraabdominal septic complications (9.1% vs 9.1%, NS). Compared to laparoscopy, robotic surgery was associated with a longer operative time (183 vs 157 minutes, p = 0.009) and a higher rate of intracorporeal anastomosis (48% vs 1.5%, p < 0.001), with specimen extraction through a Pfannenstiel incision (44% vs 1.5%, p < 0.001). Conclusion The robotic approach does not increase the risk of intraoperative incidents compared with laparoscopy and should not be contraindicated for ICR in CD. In contrast, it may reduce the overall impact of surgery by facilitating intracorporeal anastomosis and Pfannenstiel extraction in a young patient population concerned about the cosmetic results of surgery. References (1)Calini, Giacomo et al. “Ileocolic resection for Crohn’s disease: robotic intracorporeal compared to laparoscopic extracorporeal anastomosis.” Journal of robotic surgery vol. 17,5 (2023): 2157-2166. doi:10.1007/s11701-023-01635-6 (2)Abdalla, Solafah et al. "Perioperative outcomes of minimally invasive ileocolic resection for complicated Crohn disease: Results from a referral center retrospective cohort." Surgery vol. 172,2 (2022): 522-529. doi:10.1016/j.surg.2022.01.046
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