Movement Difficulties Research Articles

Exploring Contact Angle Hysteresis Behavior of Droplets on the Surface Microstructure.

It is confirmed that surfaces with specific microstructures could exhibit good superhydrophobic properties, and there are also a lot of conclusions about droplet hysteresis behavior. However, most of the research methods are based on two-dimensional ideal model and experimental observation at the macroscale. Further research needs to be conducted about the hysteresis behavior of droplets on the microstructure surface under three-dimensional conditions. In this paper, the influence of curvature variation of the liquid surface between pillars on the contact angle hysteresis (CAH) has been investigated. The simulation results were in good agreement with the experimental measurements. Analyses were conducted on the morphology change and force of the liquid surface between pillars, and an index was proposed to describe the degree of difficulty of liquid surface movement. It was revealed that a change in the direction of the surface tension at the three-phase interface caused by curvature variation of the liquid surface between pillars played an important role in the movement of the liquid surface. The greater the surface tension component in the normal direction of the liquid surface, the more likely it was for the liquid surface to advance or recede. The local curvature of the liquid surface increased or the angles between the pillars increased, and the effect of the CAH would be weakened.

Exercise Barriers and Facilitators for Breast Cancer Patients After Surgery: A Qualitative Content Analysis

PURPOSE: This study aimed to understand the barriers to exercise and facilitators of exercise for up to 4 weeks following breast cancer surgery.METHODS: A descriptive qualitative research method was used in this study. Twelve patients were recruited through purposive sampling immediately after breast cancer surgery.RESULTS: Physical aspects (pain at the surgery site, reduction in the range of motion, and decrease in fitness), environmental aspects (difficulty in movement due to drain, lack of information on exercise), and psychological aspects (concerns about side effects, fear of pain, and fear of injury during exercise) were identified as barriers to exercise. Expectation of positive effects (recovery from surgery, prevention of lymphedema, usefulness for future radiation therapy, prevention of cancer recurrence, and health management) of exercise and social support (hospital education, support from medical staff, and exercise information received via mass media) were identified as facilitators of exercise.CONCLUSIONS: We recognized different barriers to exercise and facilitators of exercise among patients who recently underwent breast cancer surgery. Future exercise intervention studies should consider minimizing such barriers and maximizing the facilitators identified in our study.

Research on the evolution of movement difficulty of competitive aerobics based on digital image processing

Competitive aerobics is a sports project which combines music, aerobics, difficulty and performance as the whole, and takes health, strength and beauty as its movement characteristics. Competitive aerobics is one of the sports that is dominated by skills, and the technical requirements are higher. Through the analysis of the existing literature, the current research on the difficulty of aerobics is only in the general qualitative description and experience summary. So far, there is no comprehensive analysis of the evolution of the competitive gymnastics articles, in the theoretical aspects of the study which is more general, limited. In this work, the method of digital image processing is used to focus on the evolution of the difficulty of aerobics. Combining the rules of the international competitive aerobics competition in each cycle, this work analyzes the statistical data of the movement difficulty of the aerobics championships, discusses the difficulty of aerobics development and evolution process, from summing up the characteristics of the development of difficult movements,the development trend of difficult movements of competitive aerobics is scientifically predicted.

Deep learning‐based scheme to diagnose Parkinson's disease

AbstractParkinson's disease (PD) is a neurological disorder of the central nervous system that causes difficulty in movement, often including tremors and rigidity. Early detection of PD can prevent symptoms up to a certain age and increase life expectancy. For this purpose, we have used brain images from magnetic resonance imaging (MRI) technique. A deeper level of feature detection in MRI can identify biomarkers that can be used to know how the disease spreads, leading to a cure in the future. With these motives, we have presented two novel approaches using deep learning (DL) techniques. 2D and 3D convolution neural networks (CNN) are used, which are trained on MRI scans in the axial plane. The dataset was constructed using images from Parkinson's progression markers initiative (PPMI). The four pre‐processing techniques used in this article are bias field correction, histogram matching, Z‐score normalization, and image resizing. Pre‐processing techniques were essential inaccurate training models. Every class prediction done by the model would have taken multiple features into account across multiple layers of the brain and not relied on a single or few important features, making DL a powerful concept. A total of 318 MRI scans were used to train and test a 2D CNN and a 3D CNN model. We have compared the models' results using different evaluation parameters such as accuracy, loss, confusion matrix, receiver operating characteristic (ROC) curve, and precision‐recall (PR) curve. The 3D model learned key features from the data and was able to classify the test data with 88.9% accuracy with 0.86 area under curve (AUC). In contrast, the 2D model achieved a mediocre accuracy of 72.22% with 0.50 AUC. This shows that the 3D model is more accurate and reliable than the 2D model.

Health-related quality of life (HRQoL) among pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibroma (PN) in the United States (U.S.).

10042 Background: PNs occur in 30-50% of pediatric patients with NF1, often resulting in debilitating pain and dysfunction. Children with NF1 PN report significantly worse HRQoL than the general population, though real-world evidence is limited. Research is needed to better characterize HRQoL among this patient population in the US. Methods: Patients ages 8-18 years with NF1 PN in the US who were treatment naïve or new users of selumetinib (≤1 month of use) were recruited through the Children’s Tumor Foundation to participate with their caregivers in an online cross-sectional survey in December 2020 and January 2021. Caregivers of similar patients ages 2-7 years also participated. Measures included the Pediatric Quality of Life Inventory (PedsQL; Acute version), EQ-5D-Y, Pain Interference Index (PII), Numeric Rating Scale (NRS-11), and the Patient-Reported Outcomes Measurement Information System (PROMIS) mobility and upper extremity functioning subscales. Patients provided self-reported responses; caregivers provided proxy responses and patient demographic and clinical characteristics. Results: 61 patients and 82 caregivers responded to the survey. Median (range) age of patients was 12.0 (8-14) years, and 53.7% were female. Most were treatment naïve (97.6%), white/Caucasian (85.4%), and had an NF1 and PN diagnosis for > 5 years (80.5% and 68.3%, respectively). On the PedsQL (range: 0-100; higher = better; mean scores typically > 80 among healthy patients), mean patient scores were 50.3 (school functioning), 56.1 (emotional functioning), 60.7 (social functioning), and 63.7 (physical functioning); the mean total score was 58.5.Caregiver-proxy mean scores were similar, ranging from 54.0 for school functioning to 65.0 for physical functioning, with a mean total score of 59.1. On the EQ-5D-Y, more than half of patients reported experiencing “some” or “a lot” of problems with pain or discomfort (65.6%) and with feeling worried, sad or unhappy (62.3%). Among patients with pain in the last 7 days, mean scores on the PII (range: 0-6; higher = more interference) were 3.0 for patients and 2.7 for caregiver proxies. Almost 75% of them reported moderate or severe pain on the NRS-11. Among patients with movement difficulty in the past 7 days, mean t-scores from the PROMIS scales (distribution mean = 50; higher = better) were 40.2 for mobility and 39.5 for upper extremity functioning among patients and 36.0 and 29.1, respectively, among caregivers. Within dyads, patients generally reported better functioning, on average, than their caregiver proxies. Conclusions: The humanistic burden of NF1 PN among this pediatric patient population is substantial, especially regarding pain, emotional functioning, and physical functioning. Results highlight an unmet need to be addressed for improving HRQoL in pediatric patients with NF1 and PN.

Natal and intergenerational dispersal of riverine smallmouth bass (Micropterus dolomieu)

Quantifying the scale of offspring dispersal is essential for understanding demographic connectivity across landscapes and rates of population spread. However, characterizing natal dispersal in fishes is complicated by the difficulties of tracking origins and movement during early life-history stages. We combined direct observation of natal dispersal based on otolith chemistry with indirect estimates of dispersal from population genetics to quantify intergenerational dispersal of smallmouth bass (Micropterus dolomieu) inhabiting a river network. Average parent–offspring dispersal was estimated as 7.7 km from genetic isolation-by-distance and demographic population data. Otolith chemistry indicated that adults were captured an average of 8.3 km from their natal tributary, supporting the genetics-based estimate. Our estimate of intergenerational dispersal is higher than previous estimates for lotic fishes and considerably higher than estimates for smallmouth bass in lake systems. Differences in availability of seasonal habitats for smallmouth bass may account for the contrasting scales of dispersal between lake and river populations. The large intergenerational dispersal distance of riverine smallmouth bass should be considered in conservation of fisheries or efforts to control invasive populations in river networks.

A COMPARATIVE STUDY TO EVALUATE THE EFFECT OF MATRA VASTI IN KHARA PAKA WITH MADHYAMA PAKA IN JANU SANDHIGATA VATA

Vasti has been told as Ardhachikitsa and is applicable in all the Vatavyadhi. As a general rule, when Rogas are caused by Vata Dosha alone, without the association of Ama, then Sneha Vasti should be given. Matra Vasti is one among the Bheda of Sneha Vasti, it can be given to any person irrespective of age and Ritu, without any strict regimen of Ahara and Vihara. SandhiVata is a Vatika disorders and Dhatukshaya is its prime factor. Vata Dosha is the regulator of other two Dosha, Dhatu and Mala and also all the body activities. Therefore, once Vata is con- trolled by Vasti, all these factors are automatically regulated, and total body equilibrium is achieved. Sandhigata Vata is characterized by symptoms like joint stiffness, joint pain, swelling and difficulty in joint movements, etc. Snehana is mentioned as one of the main treatments of Sandhigata Vata. According to therapeutic administration, Sneha Paka is mainly 3. Acharya Charaka and Vagbhata explained Sneha in Madhyama Paka for Vasti Karma, whereas Acharya Susruta opines Sneha in Khara Paka for VastiKarma. Here in this study, MatraVasti with KsheeraBala Taila prepared in two different Paka is selected. A group of 40 patients with signs and symptoms of Janu Sandhigata Vata, fulfilling the inclusion criteria and were randomly divided into two groups with number of twenty. MatraVasti with Ksheerabala Taila prepared in Khara Paka was given to Group A and Madhyama Paka was given to Group B for consecutive 9 days. Patients were evaluated thoroughly prior to the treatment, on 9th day of treatment and on 18th day of follow up period on the basis of subjective and objective parameters. Statistical analysis revealed that both groups were statistically significant in all subjective and objective criteria in after treatment results and after following up results.

Licofelone in osteoarthritis: is this the awaited drug? a systematic review

Osteoarthritis is a progressive joint disease associated with aging in elderly is, characterized by pain, inflammation, and difficulty in movement. The pathways involved in the progression of this disease remain unclear. The mediators, eicosanoids and leukotrienes are produced by COX-1/COX-2 or 5-LOX. Physicians have always used nonsteroidal anti-inflammatory drugs to treat the pain associated with osteoarthritis. A competitive inhibitor of LOX-5 and COX-2 that has both analgesic and anti-inflammatory activity is licofelone; one of the most promising candidates for the treatment of osteoarthritis is under clinical trial in treatment. A significant reduction in cartilage volume was displayed. A significant improvement over baseline on the WOMAC index and GI tolerance was also observed. Improving the symptoms related pain sensation with a happier life. With new strategies in OA, new methods to target pain, inflammation and movement restrictions would be the ultimate goal in patient satisfaction for the future. Licofelone was found to be effective compared to NSAIDs or coxibs in the treatment of OA. Does this mean this could be the answer?

Effect of ion-crosslinking on supercritical CO2 foaming behavior and foam properties of EVA/ZnO composites

How to realize the recycling of materials is an important topic for polymer materials, especially crosslinked polymers. In this work, by means of the reaction of zinc oxide (ZnO) and maleic anhydride group, ethylene-vinyl acetate copolymer (EVA)/ZnO composites with reversible ion-crosslinking structure were prepared by melt mixing method. The gel content and the degree of ion crosslinking in EVA were tracked using the THF extraction method. The presence of ion-crosslinking structure strongly affected the foaming behavior of EVA composites in supercritical CO2 (sc-CO2) molding foaming process. The influence of the ion crosslinking on the structure and properties of EVA foams was studied by means of SEM and compression set test etc. The results showed that the appropriate degree of ion-crosslinking was beneficial to increase the volume expansion rate and cell density of the obtained foams, and reduce the average cell diameter and compression set of the foams. The obtained EVA composite foams showed good resilience and melt-reprocessing performance. However, too high ion-crosslinking degree severely limited the growth of cells due to the difficulty of molecular chain movement. At the same time, the excessive ZnO in the matrix had an adverse effect on the compression set of EVA foam.

Movement performance and movement difficulties in typical school-aged children.

IntroductionDevelopmental Coordination Disorder (DCD) is an impairment of executive motor skills. Children aged 7–10 years gradually develop effective movement that enables smooth performance in various daily self-care, academic and sport activities. The purpose of this study was to examine whether the Movement Assessment Battery for Children-Second Edition-Age Band 2, (MABC2-AB2), which is a western standardized test, could be used in Thai children for differentiating between movement performance and movement difficulties.MethodThree hundred and sixty typical Thai children aged 7–10 years old were recruited from three primary schools in Chiang Mai district, Thailand. The participants were divided into four age groups and tested using the Movement Assessment Battery for Children-Second Edition-Age Band 2-Thai version (MABC2-AB2-T).ResultsManual Dexterity, Aiming and Catching, and Balance rose with age increment. Older participants had better movement performance than younger ones. The results showed that 91.11 percent of the participants had typical movement, while 3.61 and 5.28 percent of them had movement difficulty and movement at risk, respectively. In addition, three test items: Drawing Trail, Walking Heel to Toe Forward, and Hopping on Mats had a ceiling effect when used for Thai children.ConclusionThe MABC2-AB2-T could be used to assess movement performance and movement difficulties in Thai children. About 9 percent of typical Thai children aged 7–10 years old needed early intervention. Administration of the three test items may need to be revised.

An Exploratory Study of Teachers' Experiences in Physical Education With Children Thought to Have Developmental Coordination Disorder.

Teachers can create supportive conditions in physical education to mitigate experiences of stress for children with developmental coordination disorder (DCD); however, most are unfamiliar with DCD and lack adequate training to instruct children with impairments. The purpose of this study was to explore teachers' perceptions of and interactions in physical education with children thought to demonstrate functional difficulties associated with DCD. A semistructured interview was conducted with 12 teachers across all elementary years with diverse backgrounds and thematically analyzed. Four themes were produced. Teachers (a)had differing views on the etiology of children's movement difficulties, though (b)all recognized a range of difficulties children demonstrated. They (c)believed it was their role to facilitate positive experiences for these children in physical education but (d)experienced challenges in doing so. Training that increases teachers' knowledge of and abilities to address the needs of children thought to have DCD is warranted.

The concepts of form based code.(Dept.A)

In the last century the rules governing land uses appeared, the first of these rules were the Housing laws of America in 1901, after that these laws were developed and were known Zoning Codes which controlled land uses. Despite the success of these codes in solving many problems it created other problems such as the urban deformation, loss of identity, loss of social relationships, segregation between land uses, difficulty of movement. These challenges must be overcame for creating sustainable urbanism, but the zoning codes could not solve them so there is a need to search for innovative rules. At this point the Form Based Code appeared as a legislative tool which organizes urbanism in order to create sustainable urbanism. The research sheds the light on the form based code. The research aims to define the extent to which the concepts of fom based code have been realized in the reality of downtown Mansoura as an example of the Egyptian cities. This can be a guide for future development plans, which helps in defining what concepts must be focused on. The research defines the sustainable urbanism, the form based code and explains the local area of the study. The conclusion of this research reveals that there is a poor existence for some concepts of the code, and there is a great absence of most of them which causes many of architectural and urban problems ending up with the creation of a non-sustainable environment. From here there is a need to support the concepts which have poor existence to be realized fully, and search for the reasons of why other concepts were not realized, and search for ways to achieve them.

Forum Panelist 1: COVID-19 Response: BBNGO ‘crossing’ the nationality borders

The Movement Control Order (MCO) due to the COVID-19 Pandemic implemented on18 March 2020 for Malaysia and the closing of the borders between Malaysia and Thailand caused a lot of strain on the Thai citizens working in Malaysia. Many of them were unable to do their usual job especially in the restaurants all over Malaysia.Efforts were taken by the NGOs and its sponsors in Thailand to relieve the Thai citizens’ suffering. On the 13th of April an agreement was signed between the Thai Islamic Medical Association of Thailand and ‘PertubuhanGabunganBantuanBencana NGO’ Malaysia (BBNGO) to support the Thai citizens in their daily life due to the difficulties during the MCO. Majority of those affected were the restaurant workers.According to reports there were about 40,000 Thai workers in Malaysia, most of whom worked in restaurants. On 18th April 2020 The Malaysian-Thai border was opened limitedly via five checkpoints, only 350 Thai citizens were allowed to cross each day. By early May 2020 more than 7,200 Thais have crossed the border including 2,100 who entered illegally by foot or small boats.Through the agreement between TIMA and BBNGO more than 400 packs of food supply were delivered to the Thai citizens mainly in Kelantan, Terengganu, Pahang, Penang, Perlis and Kedah. Information about their addresses and phone numbers were provided. Some were delivered direct to their homes while in some areas, they were asked to collect supplies from the nearby sundry shops. Knowing the difficulty of movement between districts during the MCO, the help of local NGOs was very much needed. The ‘Pertubuhan Ikram Malaysia’ (through its Yayasan Ikram/I-Bantu), having branches in many districts of Malaysia became our main partner. The SOPs were maintained during the deliveries. Due to our good, continuous cooperation and relationship since our engagement in the 2014 flood in Kelantan and the 2016/17 flood in Southern Thailand, we have managed to implement several humanitarian missions and social activities with the Thai Islamic Medical Association and its partners. Other BBNGO activities during the MCO include aid for the university students, fresh cooked food for the front-liners, preparation of PPEs, food supply for the poor and needy.COVID-19, you are a blessing in disguise; you bring our hearts together may it be citizens or non-citizens, people of all races and religion. May Allah blessthe human race and its submission to God.International Journal of Human and Health Sciences Supplementary Issue: 2021 Page: S6

35991 Towards a Novel Robotic Control Scheme to Improve Lower Extremity Movement Post-Stroke

ABSTRACT IMPACT: Effective robotic pedaling therapy would allow stroke survivors a precision, customized, and adaptable therapy to help recover lower extremity function. OBJECTIVES/GOALS: It has been observed that people post-stroke can pedal each limb individually but not simultaneously when the bicycle is split-crank. This implies that lower extremity movement difficulties are affected more by interlimb rather than unilateral coordination deficits. This work seeks to further develop a robotic split-crank pedaling therapy device. METHODS/STUDY POPULATION: This work uses a robotic split-crank pedaling device to facilitate rehabilitation of interlimb coordination, measured by continuous relative phase (CRP) and paretic neuromuscular output. The effects of three control schemes were tested: assist, resist, and assist+resist. Each limb was strapped to a pedal which was connected to a motor. The participants were asked to pedal forward while keeping the pedals antiphase. The robot aided or resisted according to the activated control scheme. Control schemes were tested on two stroke participants. The control schemes respond proportionally to phasing deviation from 180 degrees. The assist scheme assisted the lagging limb while the resist scheme resisted the leading limb. The assist+resist did both control actions. RESULTS/ANTICIPATED RESULTS: For the assist scheme, CRP improved for participant 1 (P1) and declined for participant 2 (P2). P1 increased paretic velocity while P2 decreased. Rectus Femoris (RF) and Biceps Femoris (BF) activity of both limbs lowered for P1. RF and BF activity of both limbs remained about the same but shifted for P2. For the resist scheme, CRP improved for P1 and declined for P2. P1 increased paretic velocity while P2 decreased. P1 increased BF activity of both limbs while RF activity remained constant. P2 increased paretic BF activity and non-paretic RF activity. For the assist+resist scheme, CRP improved for both participants. Both participants increased paretic velocity. P1 increased paretic BF activity and decreased RF activity. P2 better modulated paretic BF and RF. DISCUSSION/SIGNIFICANCE OF FINDINGS: All control schemes augmented performance, however the assist+resist scheme showed the most promise in terms of CRP and muscle activity. More participants are needed to determine true effects of each control scheme. The control scheme selected will be the foundation for further improvements such as adaptive control and extrinsic feedback.

Effects of Daily Hand Activities on Age-Related Declines of Dynamic Motor Function in Individual Fingers

The present study examined the effects of daily activities of the hands on finger motor function in older adults. Maximum tapping frequency with each finger during single-finger tapping and alternate movements of index-middle, middle-ring, and ring-little finger pairs during double-finger tapping were compared between older adults who used their hands actively in their daily lives and those who did not. The active participants had significantly faster tapping rates for the ring finger in the single-finger tapping and the middle-ring finger pair in the double-finger tapping than did the inactive participants. Thus, daily activity of the hands in older adults could be effective at preventing the loss of dynamic motor function in individual fingers, especially with greater difficulty in movement, resulting from the degeneration with age.

THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS) WITH VATARI GUGGULU AND BRIHAT SIMHANADA GUGGULU

The detail knowledge on Amavata was first explained by Madhavakar, whereas Chakrapani Dutta first gave knowledge about principle and management of the disease. Amavata is a clinical entity very much similar to the chronic but active inflammatory arthropathy, the Rheumatoid arthritis. Till now, the etio-pathogenesis of Rheumatoid arthritis is not known precisely but among the hypothesis, entero-pathy along with autoimmune have important role regarding this disease. In Amavata, due to impaired functioning of 'Kayagni' the anna-rasa undergoes fermentation resulted formation of ama (biotoxin) which combines with vitiated Vata (biophysical force for movement) to form Amavata.(1) So, two important entities one is toxin and other is movement, when comes together kha vaigunya concept the disease formed which is worst one. That’s why swelling, severe pain, and restricted movements are the main features of Amavata. Severe pain, difficulty in movements, and swelling on the joints along with fever etc makes the patient’s life miserable. Although Ama and Vata are chiefly pathogenic factors, Kapha and Pitta are also invariably involved in its pathogenesis (Samprapti). The therapeutic approach should be on Vata dosha, Kapha dosha and correction of Amadosha and of Agni viz. Pitta. The line of treatment for amavata also includes langhanam, swedanam, tiktam, deepana, katu drugs and sodhana treatment like virechana, basti etc. The shamana drugs which are having Vatashamaka, Amapachaka, Ama Shoshaka, and Deepniya properties can be used in the treatment of this disease. Vatari Guggulu and Brihat simhanada guggulu carries indication for Amavata according to Bhaisajya Ratnavali. The compositions in it are approachable lieu of principles of treatment of Amavata. The clinical research shows that in TG I, 7 (46.67%) patients were got Moderate im-provement while 8 (53.33%) patients were got Mild improvement. In TG II 10 (66.67%) patients were get Moderate improvement while 5 (33.33%) patients were got Mild improvement.

The unmet clinical needs of children with developmental coordination disorder.

The aim of this study was to understand the challenges experienced by families obtaining a diagnosis and therapy for developmental coordination disorder (DCD). Parents of 435 children aged 4-18 years with persistent motor difficulties consistent with a diagnosis of DCD completed an online survey. Diagnostic timeline and diagnostic label/s received were examined, along with therapies accessed. There was inconsistent diagnostic terminology (nine separate terms) with more children diagnosed with dyspraxia (64.7%) than DCD (48.8%). Even though most parents (87.0%) reported that receiving a diagnosis was helpful, children did not receive a diagnosis until years after seeking help (mean 2.8 ± 2.3 years). Many children were diagnosed with at least one co-occurring neurodevelopmental, language or learning disorder (70.0%). Almost all families had accessed therapy for their child's movement difficulties (93.9%), but more than half did not have access to funding to support therapy costs (57.8%) and reported that the costs caused financial strain (52.6%). Two out of every three families reported that they did not feel the current level of therapy was sufficient. This critical advocacy research highlights inconsistent and incorrect terminology and the challenges families experience in obtaining a diagnosis and adequate access to therapy for their child's movement difficulties. This is the first comprehensive study to examine the challenges families experience gaining a diagnosis and therapy for their child with DCD. Families regularly experienced prolonged diagnosis; 45% waited between 2 and 4 years. There is no clear diagnostic pathway, with children more likely to be diagnosed with dyspraxia than the correct clinical diagnosis of DCD. More extensive implementation of the diagnostic guidelines into clinical practice is needed.

Fırtına Sonrası Sessizlik; Bickerstaff Beyin Sapı Ensefalitli Bir Olgu

A pediatric case with Bickerstaff’s brainstem encephalitis (BBE), which is a very rare monophasic post-infectious condition characterized by central nervous system involvement, unconsciousness, ophthalmoplegia and ataxia, is presented. Twelve years old patient was brought with difficulty in eye movements and ataxia. On the second day, she became agitated and lethargic, and then bulbar palsy and whole body paralysis developed. Upper motor neuron involvement was evident. Routine biochemical parameters and serologic tests, cranial magnetic resonance imaging, lumbar puncture, autoimmune, paraneoplastic, and electrophysiological studies were evaluated. All were normal except for the encephalopathic first electroencephalography (EEG) and the EEG repeated on the 25th day was reported to be normal. Anti-ganglioside antibody, anti-GQ1b was found positive. Intravenous immunoglobulin (IVIG) started on the fourth day. A very rapid improvement was seen in the first week of IVIG treatment. She was able to walk in the second week. She was completely normal in 3 months. Although seven years passed, our patient has not had any relapse or neurological deficit. We presented a case diagnosed as BBE treated successfully with single dose intravenous Immunoglobulin. We wanted to emphasize that BBE has a good prognosis even though it is an acutely developing severe condition.

Portable EEG Data Acquisition System for BCI Applications

Elderly people suffering from diseases like Parkinson’s disease will have difficulty in movement. For such patients, to analyse their health conditions and for diagnosis purpose, doctors may need their EEG. At present, extraction of these signals needs a short hospital visit. In this work, a simple portable brain computer interface using embedded system is developed to help such elderly people at home who may have difficulty in traveling to hospitals. The BCI system developed here utilizes EEG electrodes for signal extraction as well as high gain amplifier assembly, Raspberry Pi 4 for processing and decoding of the brain waves. The proposed system was simulated using Proteus software, fabricated on printed circuit board and interfaced with Raspberry Pi4 board. Google Colab software was used for processing the EEG dataset while integrating with Raspberry Pi4 using python coding These systems will be more practical and effective for usage outside the laboratory.

Features and diversity of symptoms of moyamoya disease in adolescents: A cluster analysis.

The purpose of this study is to explore the symptoms experienced by adolescents with moyamoya disease and to identify the characteristics of each symptom cluster associated with moyamoya disease. A retrospective and descriptive design, which is a secondary data analysis study based on electronic medical record data from hospitals. To assess the symptoms associated with moyamoya disease, a qualitative study was conducted on 12 adolescents, 12 caregivers and 12 experts on moyamoya disease. According to a qualitative study, 12 main symptoms (limb weakness, numbness, pins and needles, difficulty in speech, blurred vision, facial paralysis, hand tremors, involuntary movements, convulsions, dizziness, nausea/vomiting and headaches) were selected. Data were collected around these symptoms. The data collection was carried out through the Electronic Medical Record (EMR) data of 303 adolescents aged 13-19 who were diagnosed with moyamoya disease (ICD 10 Code: I67.5) between January 2010-December 2019 in a hospital in Seoul, South Korea. Cluster analysis was applied to identify symptom clusters with the hierarchical cluster agglomerative approach. We used the log-likelihood distance to measure the similarity of variables. Proximity between groups of variables was measured using the two-step method. The physical symptoms experienced by adolescents with moyamoya disease were 'limb weakness' - the most common - followed by a 'headache,' 'difficulty in speech,' and 'nausea/vomiting.' A total of five symptom clusters were derived: cluster 1 was characterized by 'limb weakness'; cluster 2 participants were asymptomatic or experienced 'convulsions'; cluster 3 experienced 'difficulty in speech' and 'facial paralysis'; cluster 4 is prone to 'dizziness' and 'pins and needles'; and cluster 5 displays 'headaches' and 'nausea/vomiting'. This study offers a multidimensional approach for identifying differences in clinical symptoms of moyamoya disease among adolescents. These results will help provide interventions concerning the characteristics of the symptoms of moyamoya disease among adolescents.