Background: Toinvestigatethe associationsbetweenresilience, social support, and meaning in lifeduringmidlife and the factors related to meaning in life.Methods:In this cross-sectionalstudy conducted from May 22 to June 21, 2019, 159 South Koreans aged40–64years were surveyed about resilience, social support, meaning in life, and personal characteristics.Descriptive statistics, t-tests, analysis of variance, bivariate Pearson’s correlations, and multiple regressionanalyses were performed.Conclusion: The difference in resilience according to general characteristics showed significant differencesin age, educational attainment, religious affiliation, and health status.Differencesin social support weresignificantly correlated to gender, social class, and health status. Meaning in life varied significantly accordingto differences in religious affiliation, social class, and health status. Resilience, social support, and meaningin life were significantly correlated. In the multiple regression model, resilience, social support, and selfratedhealth statussignificantly influencedmeaning in life. Strengthening resilience andsocial supportduringmidlife mightincrease meaning in life, in turn,positively influencing thequality of life inold age.
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