Differences In Migration Rates Research Articles

When gender matters: new insights into the relationships between social systems and the genetic structure of human populations

Due to its important effects on the ecological dynamics and the genetic structure of species, biologists have long been interested in gender-biased dispersal, a condition where one gender is more prone to move from the natal site. More recently, this topic has attracted a great attention from human evolutionary geneticists. Considering the close relations between residential rules and social structure, gender-biased dispersal is, in fact, regarded as an important case study concerning the effects of socio-cultural factors on human genetic variation. It all started with the seminal paper by Mark Seielstad, Erich Minch and Luigi Luca Cavalli Sforza from Stanford University (Seielstad et al. 1998). They observed a larger differentiation for Y-chromosome than mitochondrial DNA between extant human populations, purportedly a consequence of the prevalence of long-term patrilocality in human societies. Subsequent studies, however, have highlighted the need to consider geographically close and culturally homogeneous groups, disentangle signals due to different peopling events and obtain unbiased estimates of genetic diversity. In this issue of Molecular Ecology, not only do Marks et al. (2012) adopt an experimental design which addresses these concerns, but they also take a further and important step forward by integrating the genetic analysis of two distant populations, the Basotho and Spanish, with data regarding migration rates and matrimonial distances. Using both empirical evidence and simulations, the authors show that female-biased migration due to patrilocality might shape the genetic structure of human populations only at short ranges and under substantial differences in migration rates between genders. Providing a quantitative framework for future studies of the effects of residential rules on the human genome, this study paves the way for further developments in the field. On a wider perspective, Marks et al.'s work demonstrates the power of approaches which integrate biological, cultural and demographic lines of evidence in the study of relations between social and genetic structures of human populations.

Surplus Production Model Accuracy in Populations Affected by a No‐Take Marine Protected Area

AbstractMarine protected areas (MPAs) are increasingly used as a tool in fisheries management. However, implementation of an MPA violates common assumptions for fishery stock assessments that provide estimates of abundance and fishing mortality for management. Thus, it is important to understand the effects of MPAs on estimates from stock assessments. We conducted a simulation study to determine the effects of MPAs on accuracy of surplus production model (SPM) stock assessments. We simulated the dynamics of a population that had part of its range in an MPA, and we assessed the population with spatially aggregated and spatially explicit SPMs under a range of conditions, including different MPA sizes (percentage of the total stock area), different rates of migration between MPA and non‐MPA regions, and scenarios with high and low observation error in the indices of abundance. We also considered a scenario in which there was no available index of abundance within the MPA. We used the median of the absolute value of relative error and the median relative error from 200 replicates/scenario to test SPM accuracy. In most cases, spatially explicit SPMs performed better in both accuracy and bias than spatially aggregated SPMs. The accuracy of the assessments also increased as MPA size increased except under the scenario of no index of abundance within the MPA; for that scenario, accuracy increased as MPA size decreased. Monitoring of the stock within the MPA is essential for conducting accurate stock assessments in areas with MPAs.Received November 30, 2011; accepted April 7, 2012

Sex‐specific demographic behaviours that shape human genomic variation

In the human species, the two uniparental genetic systems (mitochondrial DNA and Y chromosome) exhibit contrasting diversity patterns. It has been proposed that sex-specific behaviours, and in particular differences in migration rate between men and women, may explain these differences. The availability of high-density genomic data and the comparison of genetic patterns on autosomal and sex chromosomes at global and local scales allow a reassessment of the extent to which sex-specific behaviours shape our genome. In this article, we first review studies comparing the genetic patterns at uniparental and biparental genetic systems and assess the extent to which sex-specific migration processes explain the differences between these genetic systems. We show that differences between male and female migration rates matter, but that they are certainly not the only contributing factor. In particular, differences in effective population size between men and women are also likely to account for these differences. Then, we present and discuss three anthropological processes that may explain sex-specific differences in effective population size and thus human genomic variation: (i) variance in reproductive success arising from, for example, polygyny; (ii) descent rules; and (iii) transmission of reproductive success.

The influence of migration on the maintenance of assortative mating

Rapid speciation has been shown to be plausible without the need for extreme founder events, complete geographical isolation, the existence of distinct adaptive peaks or selection for local adaptation. However, standard theory predicts that extremely low migration rates are enough to hinder divergence between populations, and thus speciation. In this study we asked how low migration rates need to be for divergence to occur and hence for speciation to be possible. We experimentally transferred individual seed beetles, Callosobruchus maculatus, between populations in the laboratory, thus mimicking different rates of migration, and used deviations from Hardy–Weinberg equilibrium as an indicator of assortative mating. We found that assortative mating was upheld for several generations in populations experiencing immigration rates of up to 8% or 13–15 immigrants per generation, despite the lack of adaptive divergence and trade-offs between the exchanging populations. However, after some generations of extensive gene flow and in the absence of selection against hybrids, the system of assortative mating faltered. Based on our results, we conclude that selection is likely to be an important factor in speciation in the face of gene flow and that without it divergence will simply come to a halt.

Outcome of Endovascular Repair of Small and Large Abdominal Aortic Aneurysms

To evaluate the outcomes of endovascular aneurysm repair (EVAR) in patients with small (≤5.4 cm) and large (≥5.5 cm) abdominal aortic aneurysms (AAAs). Data for this study were obtained from the prospective, nonrandomized, multicenter Talent enhanced Low Profile Stent trial that enrolled patients between February 2002 and April2003. A total of 156 patients with adequate preoperative imaging were identified for thisstudy. Subgroup analyses were performed for patients with small (≤5.4 cm) and large (≥5.5 cm) AAAs. Demographics, aneurysm morphology, and perioperative endpoints were assessed. Safety and effectiveness endpoints were evaluated at 30 days, 1 year, and 5 years postprocedure. Patients with small AAAs (n = 85) had similar age, gender, and medical risk profile compared with those for larger AAAs (n = 71). The proximal aortic necks in small AAAs were longer (24.7 mm vs. 20.7 mm, p = 0.05), less angulated (27.2° vs. 34.2°, p = 0.01), and smaller (24.6 mm vs. 26.1 mm, p = 0.01). Patients with small AAAs spent less time in intensive care (8.1hour vs. 26.3 hour, p = 0.03); however, other perioperative endpoints were similar. Although the group with small AAAs had a statistically significant higher rate of successful aneurysm treatment (96.8% vs. 84.9%, p = 0.04), no difference was observed in all other effectiveness endpoints at 12 months. No differences in freedom from major adverse events at 30 days and 365 days were reported. At 5 years, no differences in rates of migration, endoleaks, change in aneurysm diameter, or freedom from aneurysm-related mortality were found. Further subgroup analyses segregating patients with very small (≤5.0 cm, n = 55), small (5.1-5.4 cm, n = 30), and larger (≥5.5 cm) AAAs also showed no statistically significant differences in postoperative outcomes. In a prospective clinical trial setting with long-term follow-up, patients with small (≤5.4 cm) AAAs had aortic neck characteristics which were more favorable for EVAR. Despite these anatomic differences, clinical outcomes were similar to patients with large AAAs. Thus, we conclude that EVAR for small AAA should not be routinely recommended for patients on the basis of the assumption of improved outcomes.

An in vitro correlation of mechanical forces and metastatic capacity

Mechanical forces have a major influence on cell migration and are predicted to significantly impact cancer metastasis, yet this idea is currently poorly defined. In this study we have asked if changes in traction stress and migratory properties correlate with the metastatic progression of tumor cells. For this purpose, four murine breast cancer cell lines derived from the same primary tumor, but possessing increasing metastatic capacity, were tested for adhesion strength, traction stress, focal adhesion organization and for differential migration rates in two-dimensional and three-dimensional environments. Using traction force microscopy (TFM), we were surprised to find an inverse relationship between traction stress and metastatic capacity, such that force production decreased as the metastatic capacity increased. Consistent with this observation, adhesion strength exhibited an identical profile to the traction data. A count of adhesions indicated a general reduction in the number as metastatic capacity increased but no difference in the maturation as determined by the ratio of nascent to mature adhesions. These changes correlated well with a reduction in active beta-1 integrin with increasing metastatic ability. Finally, in two dimensions, wound healing, migration and persistence were relatively low in the entire panel, maintaining a downward trend with increasing metastatic capacity. Why metastatic cells would migrate so poorly prompted us to ask if the loss of adhesive parameters in the most metastatic cells indicated a switch to a less adhesive mode of migration that would only be detected in a three-dimensional environment. Indeed, in three-dimensional migration assays, the most metastatic cells now showed the greatest linear speed. We conclude that traction stress, adhesion strength and rate of migration do indeed change as tumor cells progress in metastatic capacity and do so in a dimension-sensitive manner.

Tracer spectrum: a visualisation method for distributed evolutionary computation

We present a novel visualisation method for island-based evolutionary algorithms based on the concept of tracers as adopted in medicine and molecular biology to follow a biochemical process. For example, a radioisotope or dye can be used to replace a stable component of a biological compound, and the signal from the radioisotope can be monitored as it passes through the body to measure the compound's distribution and elimination from the system. In a similar fashion we attach a tracer dye to individuals in each island, where each individual in any one island is marked with the same colour, and each island then has its own unique colour signal. We can then monitor how individuals undergoing migration events are distributed throughout the entire island ecosystem, thereby allowing the user to visually monitor takeover times and the resulting loss of diversity. This is achieved by visualising each island as a spectrum of the tracer dye associated with each individual. Experiments adopting different rates of migration and network connectivity confirm earlier research which predicts that island models are extremely sensitive to the size and frequency of migrations.

A 5-Year Evaluation Using the Talent Endovascular Graft for Endovascular Aneurysm Repair in Short Aortic Necks

Although endovascular aneurysm repair has been shown to be an effective way to treat abdominal aortic aneurysm (AAA), certain anatomic characteristics such as a short aortic neck, limit its applicability. Initially, commercially available devices were approved only for the treatment of AAA with an aortic neck length ≥ 15 mm. The purpose of this study was to evaluate the outcomes of the recently approved Talent endograft for AAAs with a short aortic neck length (10-15 mm). Data were obtained from the prospective, nonrandomized, multicenter Talent enhanced Low Profile Stent Graft System trial which enrolled patients between February 2002 and April 2003. A total of 154 patients with adequate preoperative imaging were identified for this study. Subgroup analyses were performed for AAA with 10-15 mm aortic neck and those with >15 mm neck. Safety and effectiveness endpoints were evaluated at 30 days, 1 year, and 5 years postprocedure. Patients treated with aortic neck lengths of 10-15 mm (n = 35) and those with >15 mm (n = 102) had similar age, gender, and risk factor profile. Both groups had similar preoperative aneurysm morphology in terms of maximum aneurysm size, degree of neck angulation, or proximal neck diameter. There were no statistically significant differences in freedom from major adverse events and mortality rates at 30 and 365 days. Similarly, there was no difference in the effectiveness endpoints at 12 months. At 5 years, there was no difference in migration rate, endoleaks, or change in aneurysm diameter from baseline. In addition, there is no difference in freedom from aneurysm-related mortality (94% vs. 99%). AAAs with short aortic necks (10-15 mm) and otherwise suitable anatomy for endovascular repair can be safely and effectively treated with the Talent endograft with excellent 1 and 5 year outcomes.

Abstract 999: The role of α-catenin homologue α-catulin during mouse development

Abstract In multicellular organisms, cell-cell contacts that are mediated by classical cadherins have essential roles in many fundamental processes, such as morphogenesis, maintenance of tissue integrity, wound healing and cell polarity. Furthermore, there is overwhelming evidence that the adherens junction (AJ) is also an important tumor and/or invasion suppressor and E-cadherin and α-catenin are very often down-regulated during tumor progression. As the primary cell-cell adhesion protein in epithelial cells, E-cadherin has long been studied in cancer progression. Similarly, additional roles for β-catenin in the Wnt signaling pathway have led to many studies of the role of β-catenin in cancer. Alpha-catenin, in contrast, has received less attention. However our recent data demonstrated that conditional loss of α-catenin in skin results in formation of squamous cell carcinoma like phenotype, accompanied by increased proliferation, motility and activation of NF-κB and its proinflammatory target genes, which account for many features of invasive epithelial cancer. The mechanism of this complex phenotype after α-catenin deletion is not well understood. Our new data show that the down-regulation of α-catenin is followed by the up-regulation of α-catenin homologue α-catulin. This protein was shown to interact directly with components of Rho GTPases and NF-κB signaling pathways, both crucial for tumor development and progression, and increase migration and survival of human squamous cell carcinoma cells. Therefore, our goal is to understand the role of α-catulin during normal development and tumor progression and how it influences the classical α-catenin function. Using a gene trap method, we have generated α-catulin KO mice. Straight α-catulin KO results in embryonic lethality, with embryos dieing around 10.5E with neural tube closure defects, craniofacial defects and hemorrhaging in the head. To study α-catulin expression pattern, we used a β-galactosidase reporter tag under endogenous α-catulin promoter, and found α-catulin to be expressed in the neural crest during development and maintained in some structures derived from neural crest cells during adulthood. Microarray analysis performed on α-catulin WT and KO embryos showed the most changes in axon guidance and Rho-mediated actin motility genes. These results led us to look at the role of α-catulin during cell migration. In vitro analyses of α-catulin WT and KO embryoid bodies and endodermal cells showed differential migration rates between the WT and KO cells. In vivo analyses by wound healing in heterozygous α-catulin mice showed an increase in α-catulin expression during wound healing. In addition, immunofluorescence staining showed α-catulin co-localized with actin cytoskeleton at the leading edge of the migrating cell. To summarize, α-catulin KO embryos have severe phenotypes and evidence suggests that α-catulin may play a role in migration during development. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 999.

The Impact of Migration on Poverty Concentrations in the United States, 1995-2000

Poverty is frequently conceptualized as an attribute of either people or places. Yet residential movement of poor people can redistribute poverty across places, affecting and reshaping the spatial concentration of economic disadvantage. In this article, we utilize 1995 to 2000 county-to-county migration data from the 2000 United States decennial census to explore how differential migration rates of the poor and nonpoor affect local incidence of poverty, and how migration reconfigures poverty rates across metropolitan, micropolitan, and noncore counties. We further examine the impact of differential migration rates on African American and Latino poverty rates, two groups that have experienced higher than average poverty rates and have a sizable presence in rural areas. Our analysis indicates that during the 1990s the poor moved at rates equal to or greater than the nonpoor, and that, especially in micropolitan counties, this movement tended to deepen existing poverty concentrations. Both African American and Latino migration patterns tended to reinforce existing poverty concentrations, a result similar to that of the population as a whole, although the migration patterns of both groups more severely exacerbated poverty in high-poverty noncore counties.

Modern changes of tidal troughs among the radial sand ridges in northern Jiangsu coastal zone

Using satellite images taken on different dates, GIS analysis of aerial photos, bathymetric maps and other field survey data, tidal troughs and major sand ridges in the northern Jiangsu coastal area were contrasted. The results show that there have been three types of movement or migration of tidal trough in this area: (1) Periodic and restricted, this type of trough usually developed along the beaches with immobile gully head as a result of the artificial dams and the swing range increased from gully head to the low reaches, so they have been obviously impacted by human activity and have longer swing periods; (2) Periodic and actively, this kind of trough, which swung with a fast rate and moved periodically on sand ridges, were mainly controlled by the swings of the host tidal troughs and hydrodynamic forces upon tidal sand ridge and influenced slightly by human constructions; (3) Steadily and slowly, they are the main tidal troughs with large scale and a steady orientation in this area and have slow lateral movement. The differences in migration mode of tidal trough shift result in different rates of migration and impact upon tidal sand ridges. Lateral accumulation on current tidal trough and deposition on abandoned tidal troughs are the two types of sedimentation of the tidal sand ridges formation. The whole radial sand ridge was generally prone to division and retreat although sand ridges fluctuated by the analysis of changes in talwegs of tidal troughs and shorelines of sand ridges.

Metapopulation dynamics for spatially extended predator–prey interactions

Traditional metapopulation theory classifies a metapopulation as a spatially homogeneous population that persists on neighboring habitat patches. The fate of each population on a habitat patch is a function of a balance between births and deaths via establishment of new populations through migration to neighboring patches. In this study, we expand upon traditional metapopulation models by incorporating spatial heterogeneity into a previously studied two-patch nonlinear ordinary differential equation metapopulation model, in which the growth of a general prey species is logistic and growth of a general predator species displays a Holling type II functional response. The model described in this work assumes that migration by generalist predator and prey populations between habitat patches occurs via a migratory corridor. Thus, persistence of species is a function of local population dynamics and migration between spatially heterogeneous habitat patches. Numerical results generated by our model demonstrate that population densities exhibit periodic plane-wave phenomena, which appear to be functions of differences in migration rates between generalist predator and prey populations. We compare results generated from our model to results generated by similar, but less ecologically realistic work, and to observed population dynamics in natural metapopulations.

Copper pollution in some vineyard soils of the Piedmont region (Italy): accumulation and mobility

Cu-based fungicides have been heavily used against the mildew caused by Plasmopara viticola, widespread in the Piedmont region (NW Italy). Vineyards with high Cu contents in the top soil, have been studied. The past Cu input was compared with the amounts of Cu actually measured. Downward migration rate of Cu was investigated by applying a mathematical model. A chemical, physical and mineralogical characterisation of the soil led to an interpretation of the remarkable difference in migration rate. Finally, the migration model was applied to forecast the future Cu evolution within the profiles.

Bond or Cage Effect: How Nitrophorins Transport and Release Nitric Oxide

Most blood-sucking insects possess salivary proteins which, upon injection into the victim's tissue, help them improve their feeding. One group of these salivary proteins takes advantage of the vasodilator properties of NO to perform this task. These proteins are the so-called nitrophorins (NPs). NPs are heme proteins that store and transport NO, which, when released in the victim's tissue, produces vasodilation and inhibition of blood coagulation. It has been proposed that NO binds tightly to NP at a low pH of around 5.6 and that once NPs are injected in the victims tissue, at a pH of approximately 7.4, a conformational change occurs which lowers NO affinity, allowing it to be released. In this work we have studied the NO release mechanism of NP4 at a molecular level using state of the art computer simulation techniques. We have used molecular dynamics (MD) simulations to study NP4 conformational dynamics at both pH values 5.6 and 7.4 and computed the corresponding free energy profile for NO release using a multiple steering molecular dynamics scheme. We also have used hybrid quantum mechanical/molecular mechanics (QM/MM) techniques to analyze the heme-NO structure and the Fe-NO bond strength in the different NP4 conformations. Our results provide the molecular basis to explain that NO escape from NP4 is determined by differential NO migration rates and not by a difference in the Fe-NO bond strength. In contrast to most heme proteins that control ligand affinity by modulating the bond strength to the iron, NP4 has evolved a cage mechanism that traps the NO at low pH and releases it upon cage opening when the pH rises.

The Histone Variant Macro-H2A Preferentially Forms “Hybrid Nucleosomes”

The histone domain of macro-H2A, which constitutes the N-terminal one third of this histone variant, is only 64% identical to major H2A. We have shown previously that the main structural differences in a nucleosome in which both H2A moieties have been replaced by macro-H2A reside in the only point of contact between the two histone dimers, the L1-L1 interface of macro-H2A. Here we show that the L1 loop of macro-H2A is responsible for the increased salt-dependent stability of the histone octamer, with implications for the nucleosome assembly pathway. It is unknown whether only one or both of the H2A-H2B dimers within a nucleosome are replaced with H2A variant containing nucleosomes in vivo. We demonstrate that macro-H2A preferentially forms hybrid nucleosomes containing one chain each of major H2A and macro-HA in vitro. The 2.9-A crystal structure of such a hybrid nucleosome shows significant structural differences in the L1-L1 interface when comparing with homotypic major H2A- and macro-H2A-containing nucleosomes. Both homotypic and hybrid macro-nucleosome core particles (NCPs) are resistant to chaperone-assisted H2A-H2B dimer exchange. Together, our findings suggest that the histone domain of macro-H2A modifies the dynamic properties of the nucleosome. We propose that the possibility of forming hybrid macro-NCP adds yet another level of complexity to variant nucleosome structure and function.

Integrating patterns across multiple genetic markers to infer spatial processes

Landscape geneticists can take considerable advantage of differences in the action of evolutionary forces (mutation, migration, selection, and drift) on different loci within the genome. Appropriate comparisons among loci allow researchers to isolate and study the effects of these processes. For example, the organelles are typically inherited maternally (but occasionally paternally), and so will experience migration only when females or seeds disperse (males or pollen in the paternally inherited organelles). Thus, the comparison with biparentally inherited loci allows inferences about the differential migration rates of male vs. female animals or of seeds vs. pollen in plants. Conversely, all biparentally inherited nuclear loci should experience the same levels of migration and drift. Thus, loci that show unusually large levels of variation across the landscape (as compared with the bulk of loci) may be reflecting the action of spatially varying natural selection (local adaptation). Such comparisons are conceptually straightforward, but are complicated by the high intrinsic variability of stochastic neutral processes. Careful statistical analysis is needed to avoid over-interpreting differences among loci. Inferences will be most robust when both genetic and non-genetic data can be integrated, and the collaboration of landscape ecologists with geneticists promises to be particularly fruitful.

The Concerted Modulation of Proliferation and Migration Contributes to the Specification of the Cytoarchitecture and Dimensions of Cortical Areas

Regionalization of cell cycle kinetics of cortical precursors has been described in nonhuman primates and rodents indicating a fate map of areas as distinct proliferative programs in the germinal zones of the neocortex. It remains to be understood how proliferative gradients during corticogenesis are transcribed into a stepwise function to form adult areal borders. Here we have used the monkey areas 17 and 18, which show striking cytoarchitectonic differences, as a model system for studying how developmental events establish areal boundaries in the adult. We present data indicating that the events that are involved in the formation of a sharp border separating 2 areas involve an orchestration of diverse phenomena including differential rates of proliferation, migration, and tangential expansion.

Postoperative clodronate decreases prosthetic migration: 4–year follow-up of a randomized radiostereometric study of 50 total knee patients

Background We have previously reported that 6 months of oral treatment with clodronate reduced the migration of the NexGen total knee prosthesis during the first postoperative year, as measured by radiostereometry (RSA). We now report the 4-year results.Methods This was a double-blind randomized study, using RSA with maximal total point motion (MTPM).Results With analysis according to the “intention to treat” principle, the only remaining difference between the groups at 4 years was reduced rotation around the transverse axis (a secondary variable) in the clodronate group. However, 3 patients (all clodronate) did not take any tablet after surgery. If they are excluded, there was an almost statistically significant difference between the groups at 4 years regarding MTPM from baseline, with the clodronate group showing 25% less migration. From 1 to 4 years, there was no difference in migration rate by MTPM, but there was a continuous increase in rotation around the transverse axis in the controls, which differed from the clodronate group. There were no cases of aseptic loosening. 2 patients had migration of more than 1.3 mm from baseline to 4 years; neither of them had taken clodronate. The others had migration of less than 0.9 mm.Interpretation Because migration was clearly reduced by clodronate during the first postoperative year, and there was still a difference at 4 years when analyzed per protocol, it appears likely that this treatment can diminish the risk of loosening. The difference in the number of outliers also points in this direction, and may be more relevant than mean migration values.

Gender-specific amplification of Japanese macaque genes using primers for the human DYS391 and DYS438 loci

The species specificity of 10 human Y chromosomal short tandem repeat loci, DYS19, DYS385, DYS389, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439, was examined in the Japanese macaque, Macaca fuscata. Primers for loci DYS391 and DYS438 only yielded an amplification product from male samples. The PCR products amplified with the DYS391 primers showed no inter-individual differences in migration rate in electrophoretic experiments. Sequence analysis revealed that these PCR products consisted of 287 bases containing tandem repeats of TC and TATC. The numbers of TC and the TATC repeats varied between individuals. The TC repeat does not exist in human and chimpanzee sequences. The PCR products amplified by the DYS438 primers provided no evidence of inter-individual variation between the six male Japanese macaque samples. In the Japanese macaque, PCR gives a 184 base pair product, in contrast to human sample from which the products are 203–233 bases in size. The primers for four loci, DYS19, DYS385, DYS389 and DYS437 produced PCR products from both male and female Japanese macaques. The primers for the other loci, DYS390, DYS392, DYS393 and DYS439, did not yield PCR products.

Electronic identification in rabbits: two body sites of injectable transponder

Identification and monitoring of farm animals are effective tools for traceability. Actual livestock identification systems (ear-tags, tattoos, etc.) are not completely efficient and offer some inconveniences. The use of injectable transponders might be a reliable method for individual identification, allowing the improvement of the data recording and the farm management. The aim of this experiment was to evaluate the applicability of injectable transponder in live rabbits. A total of 40 fattening rabbits of 55 days old were injected with 23 mm passive FDX-B transponders (Datamars, Switzerland), preloaded into a needle in a sterilised packaged and applied by using a transponder injector (Planet ID, Germany). Two body locations for transponder’s injection were studied: laterally to the neck (n=20) and armpit (n=20). Readings of the transponders were performed using portable ISO transceiver, before injection, after injection, the day after, after one week, after one month, before the slaughtering process. Rabbits were weighted at the injection, one week and one month after injection, and at slaughtering; a control group of not treated animals were weight to compare the effect of manipulation. Growth performance were studied by analysis of variance, using of GLM procedure. A χ2 test was used to analyse difference in migration rate. Readability of transponders in the fatteners until slaughterhouse was 100%. Recovery of transponder during the slaughtering process was easy with 100% of transponders recovered. Body site of injection didn’t affect the migration rate, nevertheless it was low. In one animal, the transponder was recovered into the scapular muscle. No harmful effects of the transponder injection on the animals were observed. Weight difference of animals was not significant for the two body site of injection, compare to the control group. Preliminary results showed that transponders can be used as a method for traceability and monitoring of live rabbits, allowing the improvement of the management of a farm.