Pitch Differences Research Articles

Effect of Pitch Difference on Stress Distribution of Thread Pair and Preload

Effect of Pitch Difference on Stress Distribution of Thread Pair and Preload

Effect of Nut Height on Tightening and Untightening of Pitch Difference Nut

Effect of Nut Height on Tightening and Untightening of Pitch Difference Nut

Simultaneous bilinguals who do not speak a tone language show enhancement in pitch sensitivity but not in executive function

Abstract Previous studies have reported perceptual advantages, such as when discriminating non-native linguistic or musical pitch differences, among first-year infants growing up in bilingual over monolingual environments. It is unclear whether such effects should be attributed to bilinguals’ enhanced perceptual sensitivity and/or cognitive abilities, and whether such effects would extend to adulthood. Twenty-four Dutch, 24 Dutch simultaneous bilingual (DSB), and 24 Chinese Mandarin speakers were examined by three sets of tasks assessing their linguistic pitch and music perception, executive function, as well as interactions across these modalities. Results showed degrees of advantages for DSB and Chinese participants’ over their Dutch peers in lexical tone discrimination and pitch-related music tasks. In tasks related to executive function, no difference was observed between DSB and Dutch participants, while Chinese participants’ performances were modulated by cognitive interference of language processing. Findings suggest that listeners’ enhanced sensitivity to linguistic and musical pitch may stem from acoustic (DSB) and experience (Chinese) rather than cognitive factors. Moreover, Dutch participants showed robust correlations between their linguistic and musical pitch perception, followed by limited correlations in DSB, and virtually no correlation among Chinese participants, illustrating how distinct language experiences can lead to specific pitch perception patterns between language and music.

Suppression of Pitch Labeling: No Evidence for an Impact of Absolute Pitch on Behavioral and Neurophysiological Measures of Cognitive Inhibition in an Auditory Go/Nogo Task.

Pitch labeling in absolute pitch (AP), the ability to recognize the pitch class of a sound without an external reference, is effortless, fast, and presumably automatic. Previous studies have shown that pitch labeling in AP can interfere with task demands. In the current study, we used a cued auditory Go/Nogo task requiring same/different decisions to investigate both behavioral and electrophysiological correlates of increased inhibitory demands related to automatic pitch labeling. The task comprised two Nogo conditions: a Nogo condition with pitch differences larger than one semitone, and a second Nogo condition with pitch differences of only a quarter semitone. The first Nogo condition tested if auditory-related inhibition processes are generally altered in AP musicians. The second Nogo condition tested the suppressibility of the pitch labeling using a Stroop-like effect: the two tones belonged to the same pitch class but were not identical in terms of tone frequency. If pitch labeling cannot be suppressed, the conflicting information would be expected to increase the inhibitory load in AP musicians. Our data provided no evidence for an increased difficulty to inhibit a prepotent response or to suppress conflicting pitch-labeling information in AP: AP musicians showed similar commission error rates as non-AP musicians in both Nogo conditions. N2d and P3d amplitudes of AP musicians were also comparable to those of non-AP musicians. The event-related potentials (ERPs) were, however, modulated by the Nogo condition, probably indicating an effect of stimulus similarity. It is possible that, depending on the context, pitch labeling in AP musicians is not entirely automatic and can be suppressed.

Binaural Pitch Fusion in Children With Normal Hearing, Hearing Aids, and Cochlear Implants.

Binaural pitch fusion is the perceptual integration of stimuli that evoke different pitches between the ears into a single auditory image. Adults who use hearing aids (HAs) or cochlear implants (CIs) often experience abnormally broad binaural pitch fusion, such that sounds differing in pitch by as much as 3 to 4 octaves are fused across ears, leading to spectral averaging and speech perception interference. The main goal of this study was to measure binaural pitch fusion in children with different hearing device combinations and compare results across groups and with adults. A second goal was to examine the relationship of binaural pitch fusion to interaural pitch differences or pitch match range, a measure of sequential pitch discriminability. Binaural pitch fusion was measured in children between the ages of 6.1 and 11.1 years with bilateral HAs (n = 9), bimodal CI (n = 10), bilateral CIs (n = 17), as well as normal-hearing (NH) children (n = 21). Depending on device combination, stimuli were pure tones or electric pulse trains delivered to individual electrodes. Fusion ranges were measured using simultaneous, dichotic presentation of reference and comparison stimuli in opposite ears, and varying the comparison stimulus to find the range that fused with the reference stimulus. Interaural pitch match functions were measured using sequential presentation of reference and comparison stimuli, and varying the comparison stimulus to find the pitch match center and range. Children with bilateral HAs had significantly broader binaural pitch fusion than children with NH, bimodal CI, or bilateral CIs. Children with NH and bilateral HAs, but not children with bimodal or bilateral CIs, had significantly broader fusion than adults with the same hearing status and device configuration. In children with bilateral CIs, fusion range was correlated with several variables that were also correlated with each other: pure-tone average in the second implanted ear before CI, and duration of prior bilateral HA, bimodal CI, or bilateral CI experience. No relationship was observed between fusion range and pitch match differences or range. The findings suggest that binaural pitch fusion is still developing in this age range and depends on hearing device combination but not on interaural pitch differences or discriminability.

Binaural Pitch Fusion: Binaural Pitch Averaging in Cochlear Implant Users With Broad Binaural Fusion.

Individuals who use hearing aids (HAs) or cochlear implants (CIs) can experience broad binaural pitch fusion, such that sounds differing in pitch by as much as 3 to 4 octaves are perceptually integrated across ears. Previously, it was shown in HA users that the fused pitch is a weighted average of the two monaural pitches, ranging from equal weighting to dominance by the lower pitch. The goal of this study was to systematically measure the fused pitches in adult CI users, and determine whether CI users experience similar pitch averaging effects as observed in HA users. Twelve adult CI users (Cochlear Ltd, Sydney, Australia) participated in this study: six bimodal CI users, who wear a CI with a contralateral HA, and six bilateral CI users. Stimuli to HA ears were acoustic pure tones, and stimuli to CI ears were biphasic pulse trains delivered to individual electrodes. Fusion ranges, the ranges of frequencies/electrodes in the comparison ear that were fused with a single electrode (electrode 22, 18, 12, or 6) in the reference ear, were measured using simultaneous, dichotic presentation of reference and comparison stimuli in opposite ears, and varying the comparison stimulus. Once the fusion ranges were measured, the fused binaural pitch of a reference-pair stimulus combination was measured by finding a pitch match to monaural comparison stimuli presented to the paired stimulus ear. Fusion pitch weighting in CI users varied depending on the pitch difference of the reference-pair stimulus combination, with equal pitch averaging occurring for stimuli closer in pitch and lower pitch dominance occurring for stimuli farther apart in pitch. The averaging region was typically 0.5 to 2.3 octaves around the reference for bimodal CI users and 0.4 to 1.5 octaves for bilateral CI users. In some cases, a bias in the averaging region was observed toward the ear with greater stimulus variability. Fusion pitch weighting effects in CI users were similar to those observed previously in HA users. However, CI users showed greater inter-subject variability in both pitch averaging ranges and bias effects. These findings suggest that binaural pitch averaging could be a common underlying mechanism in hearing-impaired listeners.

A Pitch and Noise Robust Keyword Spotting System Using SMAC Features with Prosody Modification

Spotting of keywords in continuous speech signal with the aid of the computer is called a keyword spotting (KWS) system. A variety of strategies have been suggested in the literature to detect keywords from the adult’s speech effectively. However, only a limited number of studies have been reported for KWS in children’s speech. Due to the difference in physiological properties, the pitch and speaking rate of children’s differ from the adult’s. Consequently, KWS system model parameters trained on the speech data from adult’s signal yield poor performance for children speech. In this paper, we have developed a KWS system for spotting keywords from children’s speech using models trained on adults’ speech. The proposed approach uses spectral moment time–frequency distribution augmented by low-order cepstral (SMAC) as the front-end feature. The mismatches due to differences in pitch and speaking rate of children and adult speakers are further mitigated by data-augmented training using explicit pitch and speaking rate modifications. The experimental findings presented in this paper show that the SMAC feature offers significantly better output for both clean and noisy test conditions than the conventional Mel frequency cepstral coefficients.

Image Guidance with Alignment To Bladder-Rectal Interface Versus Pelvic Bone In Post-Prostatectomy Radiotherapy: Implications For Concurrent Nodal Irradiation

The bladder-rectal interface (BRI) position is often dependent on bladder and rectal filling in post-prostatectomy patients. Nodal irradiation is of increasing importance given recent randomized data. It is unknown how alignment to the BRI may impact nodal coverage. We hypothesized that the shifts between alignment to the BRI vs pelvic bone would fall within the standard nodal PTV expansion. CBCTs from patients receiving prostate bed RT using 6 degrees of freedom (6DOF) couch were analyzed. At time of treatment, each CBCT was approved by a prostate specialized radiation oncologist prioritizing alignment to the BRI and prostate bed. Retrospectively each CBCT was re-aligned to pelvic bone. Reference bone points were chosen to represent the superior extent of pelvic nodal target volumes {midline sacral promontory (SP) and anterior aspect of sacroiliac joints at the S1-S2 (LSI and RSI)}. Three cardinal coordinates of each reference point (x, y, and z), were transformed to the machine coordinate system. Transformation matrices were defined by the parameters: lat (x), vert (y), long (z), pitch, roll, and rotation obtained with prospective matching. Using transformation matrices, alignment to the BRI was compared to bone alignment for each reference point by differences between the two sets of coordinates (x”-x’), (y”-y’), (z”-z’). A total of 139 CBCT from 14 patients were evaluated. Differences between coordinates with both alignment techniques were calculated and evaluated across all image sets (see table below). Mean differences between spatial alignment to BRI vs bone were <1.5 mm and >95% of all offsets were ≤5 mm. Approximately 75% of all coordinate differences were ≤1 mm and 90% were ≤3 mm. Less than 4% were >5 mm. Only 2 patients (4 CBCTs) exhibited >7 mm offsets between BRI and bone points. Coordinate differences >3 mm and >5 mm were more common in y (12.5% and 6%) and z (14.6% and 2.9%) than in x dimension (1.4% and 1.4%), respectively. Differences in pitch, roll, and rotation >1° were noted in n = 8, 3, and 1 CBCT sets, respectively. These data suggest that alignment to the prostate bed and BRI did not result in large offsets at the superior aspect of the pelvis. With rare exception, the required shifts should fall within the standard nodal PTV expansion. The impact of bladder and rectal filling on nodal target alignment and coverage is the subject of ongoing investigation.Abstract 4102; TableMean (mm)Std Dev (mm)≤ 1 mm (n)>1-3 mm (n)>3-5 mm (n)>5-7 mm (n)>7 mm (n)Point 1 SPx0.33 (0-8.72)0.951307011y1.40 (0-11.18)1.938140963z0.97 (0-5.92)1.50102191440Point 2 LSIx0.37 (0-8.81)0.981307011y1.39 (0-11.17)1.938042953z0.97 (0-5.93)1.48102161830Point 3 RSIx0.36 (0-8.64)0.941307011y1.40 (0-11.17)1.938141953z1.03 (0-6.20)1.55100171750 Open table in a new tab

Radiographic Outcomes in the Treatment of Type II Adult Acquired Flatfoot Deformity Following Lateral Column Lengthening with a Titanium Wedge versus Autograft or Allograft

Category:Midfoot/ForefootIntroduction/Purpose:Lateral column lengthening (LCL) is a surgical procedure used to manage forefoot abduction occurring in patients with stage IIB Adult Acquired Flat Foot Deformity (AAFD). This procedure utilizes an opening wedge osteotomy of the calcaneus which is then filled with autograft, allograft, or a titanium wedge. The primary aim of this study was to compare the radiographic outcomes of these different bone substitutes in the setting of stage IIB AAFD with the use of LCL.Methods:All patients who underwent LCL from October 2008 until October 2018 were retrospectively reviewed. Preoperative weight bearing radiographs, initial postoperative radiographs and 1-year weight bearing radiographs were reviewed. The following radiographic measurements were recorded: talonavicular uncoverage angle, incongruency angle, and calcaneal pitch.Results:A total of 44 patients were included in our study. The mean age of the cohort was 54 (range 18-74). The study cohort was divided into two groups. There were 17 (38.7%) patients that received a titanium wedge and 27 (61.5%) that received autograft or allograft. Patients that underwent LCL with the autograft/allograft group were significantly older (p=0.006). Patients who underwent LCL with a titanium wedge had a significantly higher preoperative talonavicular angle (p=0.013). There were no significant differences in post-operative talonavicular uncoverage angle, incongruency angle or calcaneal pitch at 6 months or 1 year.Conclusion:Adult acquired flat foot deformity is a difficult disorder to treat surgically. Lateral column lengthening is a common surgical procedure used to treat forefoot abduction that occurs. Our results show that at 6 months and 1 year no radiographic difference exists between autograft/allograft bone substitutes versus titanium wedge in LCL. Future research should evaluate the differences in patient reported outcomes between autograft/allograft versus titanium wedge bone substitutes.

Effects of steady background noise on benefits from voice pitch differences in a “Cocktail Party” environment

Voice pitch is an important cue for auditory object segregation in a multi-talker environment. A recent study showed that the ability to segregate and identify speech based on voice pitch differences is highly correlated with the breadth of binaural pitch fusion, the perceptual integration of dichotic stimuli that evoke different pitches across ears [Oh et al., ASA (2018)]. The goal of this study was to investigate effects of steady background noise on binaural pitch fusion and speech perception abilities in background noise consisting of multiple talkers. Subjects were tested in both quiet and various “soft” audible noise levels (15, 5, and -5 dB SNR) inboth ears with the following experiments. First, binaural pitch fusion measurements were conducted using pure tones. Second, speech on speech masking performance was measured as the threshold target-to-masker ratio needed to understand a target talker in the presence of either same- or different-gender masker talkers. The results showed that both breadth of binaural pitch fusion was minimized and voice pitch difference benefit in multi-talker conditions was maximized at an optimal amount of the noise levels, which is called suprathreshold stochastic resonance effects. A strong negative correlation was also observed between voice gender benefit and breadth of binaural fusion. The findings suggest potential rehabilitation approaches, such as low-level noise, to sharpen binaural pitch fusion and improve related speech perception ability in multi-talker listening environments.

Preliminary study on phonetic characteristics of patients with pulmonary nodules

ObjectivePulmonary nodules (PNs) are one of the imaging manifestations of early lung cancer screening, which should receive more attention. Traditional Chinese medicine believes that voice changes occur in patients with pulmonary diseases. The purpose of this study is to explore the differences in phonetic characteristics between patients with PNs and able-bodied persons. MethodsThis study explores the phonetic characteristics of patients with PNs in order to provide a simpler and cheaper method for PN screening. It is a case-control study to explore the differences in phonetic characteristics between individuals with and without PNs. This study performed non-parametric statistics on acoustic parameters of vocalizations, collected from January 2017 to March 2018 in Shanghai, China, from these two groups; it explores the differences in third and fourth acoustic parameters between patients with PNs and a normal control group. At the same time, computed tomography (CT) scans, course of disease, combined disease and other risk factors of the patients were collected in the form of questionnaire. According to the grouping of risk factors, the phonetic characteristics of the patients with PNs were analyzed. ResultsThis study was comprised of 200 patients with PNs, as confirmed by CT, and 86 healthy people that served as a control group. Among patients with PNs, 43% had ground glass opacity, 32% had nodules with a diameter ≥ 8 mm, 19% had a history of smoking and 31% had hyperlipidemia. Compared with the normal group, there were statistically significant differences in pitch, intensity and shimmer in patients with PNs. Among patients with PNs, patients with diameters ≥ 8 mm had a significantly higher third formant. There was a significant difference in intensity, fourth formant and harmonics-to-noise ratio (HNR) between smoking and non-smoking patients. Compared with non-hyperlipidemia patients, the pitch, jitter and shimmer of patients with PNs and hyperlipidemia were higher and the HNR was lower; these differences were statistically significant. ConclusionThis measurable changes in vocalizations can be in patients with PNs. Patients with PNs had lower and weaker voices. The size of PNs had an effect on the phonetic formant. Smoking may contribute to damage to the voice and formant changes. Voice damage is more pronounced in individuals who have PNs accompanied by hyperlipidemia.

Analysis of Effect of Slight Pitch Difference on the Fatigue Life of Bolt

In this work fatigue failure is examine for bolt with nut connections, when a slight pitch difference is established between bolt and nut. To improve the fatigue life, there are three types of slight pitch difference processed on the specimens and results are discussed in terms of FEM analysis. Taking into consideration the standard dimension bolt and nut connection having pitch difference of (α) =0 μm, the bolt fracture does not happen at the No. 1 thread by introducing a slight pitch difference of (α) =5 μm and pitch difference (α) =15 μm, is observed. Furthermore, it is having been discovered that the fatigue life of bolt can be increase by introducing some slight pitch differences. The effect of bolt-nut connection with slight pitch difference, on the fatigue failure of bolt is discovered.

Brainwave entrainment to minimise sedative drug doses in paediatric surgery: a randomised controlled trial

BackgroundAnaesthetic drugs may cause neuroapoptosis in children and are routinely used off-label in specific age groups. Techniques that reduce anaesthetic drug dose requirements in children may thus enhance the safety of paediatric sedation or anaesthesia. Brainwave entrainment, notably in the form of auditory binaural beats, has been shown to have sedative effects in adults. We evaluated the influence of brainwave entrainment on propofol dose requirements for sedation in children. MethodsWe randomised 49 boys scheduled for sub-umbilical surgery under caudal blockade to an entrainment or a control group. Small differences in pitch were applied to each ear to create binaural beats, supplemented by synchronous visual stimuli, within the electroencephalographic frequency bands seen during relaxation and (rapid eye movement/non-rapid eye movement) sleep. After establishment of caudal block, propofol infusion was started at 5 mg kg−1 h−1. Intraoperatively, the infusion rate was adjusted every 5 min depending on the sedation state judged by the bispectral index (BIS). The infusion rate was decreased by 1 mg kg−1 h−1 if BIS was <70, and was increased if BIS was >70, heart rate increased by 20%, or if there were other signs of inadequate sedation. ResultsMean propofol infusion rates were 3.0 (95% confidence interval [CI]: 2.4–3.6) mg kg−1 h−1vs 4.2 (95% CI: 3.6–4.8) mg kg−1 h−1 in the entrainment and control groups, respectively (P<0.01). BIS values were similar in the two groups. ConclusionsBrainwave entrainment effectively reduced the propofol infusion rates required for sedation in children undergoing surgery with regional anaesthesia. Further studies are needed to investigate the possibility of phasing out propofol infusions completely during longer surgical procedures and optimising the settings of brainwave stimulation. Clinical trial registrationDRKS00005064.

Absolute pitch learning in adults speaking non-tonal languages.

Absolute pitch (AP) refers to labelling individual pitches in the absence of external reference. A widely endorsed theory regards AP as a privileged ability enjoyed by selected few with rare genetic makeup and musical training starting in early childhood. However, recent evidence showed that even adults can learn AP, and some can attain a performance level comparable to natural AP possessors. These training studies involved native tonal language speakers, whose acquisition of AP might be facilitated by tonal language exposure during early childhood. In this study, adults speaking non-tonal languages went through AP training that was 20-hr long, computerised and personalised. Performance on average improved, which was accompanied by enhanced working memory for tones, whereas relative pitch judgement and sensitivity to small pitch differences remained unchanged. Notably, two out of 13 learned to label all 12 pitches within an octave, with accuracy and response time comparable to natural AP possessors. Overall, the findings suggest that tonal language exposure is not a prerequisite for AP learning in adulthood. The understanding of the origin of AP would benefit from considering the role of lifelong learning instead of focusing only on early childhood experience.

Exploratory dynamics of vocal foraging during infant-caregiver communication

We investigated the hypothesis that infants search in an acoustic space for vocalisations that elicit adult utterances and vice versa, inspired by research on animal and human foraging. Infant-worn recorders were used to collect day-long audio recordings, and infant speech-related and adult vocalisation onsets and offsets were automatically identified. We examined vocalisation-to-vocalisation steps, focusing on inter-vocalisation time intervals and distances in an acoustic space defined by mean pitch and mean amplitude, measured from the child’s perspective. Infant inter-vocalisation intervals were shorter immediately following a vocal response from an adult. Adult intervals were shorter following an infant response and adult inter-vocalisation pitch differences were smaller following the receipt of a vocal response from the infant. These findings are consistent with the hypothesis that infants and caregivers are foraging vocally for social input. Increasing infant age was associated with changes in inter-vocalisation step sizes for both infants and adults, and we found associations between response likelihood and acoustic characteristics. Future work is needed to determine the impact of different labelling methods and of automatic labelling errors on the results. The study represents a novel application of foraging theory, demonstrating how infant behaviour and infant-caregiver interaction can be characterised as foraging processes.

Enhanced Pitch Discrimination for Cochlear Implant Users with a New Haptic Neuroprosthetic

The cochlear implant (CI) is the most widely used neuroprosthesis, recovering hearing for more than half a million severely-to-profoundly hearing-impaired people. However, CIs still have significant limitations, with users having severely impaired pitch perception. Pitch is critical to speech understanding (particularly in noise), to separating different sounds in complex acoustic environments, and to music enjoyment. In recent decades, researchers have attempted to overcome shortcomings in CIs by improving implant technology and surgical techniques, but with limited success. In the current study, we take a new approach of providing missing pitch information through haptic stimulation on the forearm, using our new mosaicOne_B device. The mosaicOne_B extracts pitch information in real-time and presents it via 12 motors that are arranged in ascending pitch along the forearm, with each motor representing a different pitch. In normal-hearing subjects listening to CI simulated audio, we showed that participants were able to discriminate pitch differences at a similar performance level to that achieved by normal-hearing listeners. Furthermore, the device was shown to be highly robust to background noise. This enhanced pitch discrimination has the potential to significantly improve music perception, speech recognition, and speech prosody perception in CI users.

Prevailing torque and residual prevailing torque of Bolt-Nut connections having slight pitch difference

In this study, by applying three-dimensional FEM, the nut screwing process is analyzed to obtain the prevailing torque Tp confirming anti-loosening. Since the nut unscrewing properties after the nut tightening is more important to prevent the nut self-loosening, the nut unscrewing is also analyzed to obtain the residual prevailing torque Tp u newly defined in this process. Both results of Tp and Tp u are in good agreement with the experimental results. With increasing the pitch difference, the residual prevailing torque Tp u increases as well as the prevailing torque Tp .

Three-dimensional finite element analysis for prevailing torque of bolt-nut connection having slight pitch difference

In a vast industrial field, the bolt-nut connection is widely used and unitized as an important machine component. In order to improve safety and for cost reduction, cheap bolt-nut connections with excellent anti-loosening performance are always needed. In this paper, the slight pitch difference is considered between the nut and bolt threads to improve the anti-loosening by focusing on the prevailing torque Tp. In the first place, during the nut screwing process, the bolt axial force Fa caused by the pitch difference is examined because previously Fa was studied by the axisymmetric FEM simulation as a substitute of the prevailing torque Tp. Next, the prevailing torque Tp is directly analyzed by changing the pitch difference through the 3D FEM simulation. The obtained prevailing torque needed for the nut rotation is in consonance with the measured value experimentally. By considering manufacturing error sometimes included, finally, the real pitch difference or of the nut is identified from the number of nut thread in contact with the bolt thread, which is measured experimentally. Then, the correctness of this α is confirmed through the prevailing torque obtained by 3D FEM simulation.

Over-expression of transcription factor ARK1 gene leads to down-regulation of lignin synthesis related genes in hybrid poplar \u2018717\u2019

Improving wood growth rate and wood quality are worthy goals in forest genetics and breeding research. The ARK1 gene is one member of the ARBORKNOX family in all plants, which play an essential role in the process of plant growth and development, but the mechanism associated with its gene network regulation is poorly investigated. In order to generate over-expression transgenic hybrid poplar, the agrobacterium-mediated transformation was used to obtain transgenic hybrid poplar ‘717’ plants to provide insight into the function of the ARK1 gene in poplar. Moreover, the morphology of transgenic plants was observed, and transcriptome analysis was performed to explore the ARK1 gene function. The results showed that there were significant differences in pitch, stem diameter, petiole length, leaf width, leaf length and seedling height between ARK1 transgenic seedlings and non-transgenic seedlings. The transgenic seedlings usually had multiple branches and slender leaves, with some leaves not being fully developed. The results of transcriptome analysis showed that the differentially expressed genes were involved in the growth of poplars, including proteins, transcription factors and protein kinases. Genes related to the positive regulation in plant hormone signal transduction pathways were up-regulated, and the genes related to lignin synthesis were down-regulated. The RT-qPCR analysis confirmed the expression levels of the genes involved in the plant hormone signal transduction pathways and phenylpropanoid pathway. In conclusion, the ARK1 gene had a positive regulatory effect on plant growth, and the gene’s coding enzymes related to lignin synthesis were down-regulated.

How musical experience affects tone perception efficiency by musicians of tonal and non-tonal speakers?

PurposeTo investigate if, regardless of language background (tonal or non-tonal), musicians may show stronger CP than non-musicians; To examine if native speakers of English (English or non-tonal musicians henceforth) or Mandarin Chinese (Mandarin or tonal musicians henceforth) can better accommodate multiple functions of the same acoustic cue and if musicians’ sensitivity to pitch of lexical tones comes at the cost of slower processing.MethodEnglish and Mandarin Musicians and non-musicians performed a categorical identification and a discrimination task on rising and falling continua of fundamental frequency on two vowels with 9 duration values.ResultsNon-tonal musicians exhibited significantly stronger categorical perception of pitch contour than non-tonal non-musicians. However, tonal musicians did not consistently perceive the two types of pitch directions more categorically than tonal non-musicians. Both tonal and non-tonal musicians also benefited more from increasing stimulus duration in processing pitch changes than non-musicians and they generally require less time for pitch processing. Musicians were also more sensitive to intrinsic F0 in pitch perception and differences of pitch types.ConclusionThe effect of musical training strengthens categorical perception more consistently in non-tonal speakers than tonal speakers. Overall, musicians benefit more from increased stimulus duration, due perhaps to their greater sensitivity to temporal information, thus allowing them to be better at forming a more robust auditory representation and matching sounds to internalized memory templates. Musicians also attended more to acoustic details such as intrinsic F0 and pitch types in pitch processing, and yet, overall, their categorization of pitch was not compromised by traces of these acoustic details from their auditory short-term working memory. These findings may lead to a better understanding of pitch perception deficits in special populations, particularly among individuals diagnosed with autism spectrum disorder (ASD).