Differences In Carbohydrate Intake Research Articles

Insights into medieval rural lives: A paleo-odontological investigation of two central European communities

ObjectiveOral status is an important indicator of past lifestyles. Determining the presence and extent of oral pathologies helps reconstruct average oral health, paramasticatory activities and diet of ancient and historical populations. DesignIn this study, the dental remains from the early medieval cemetery of Früebergstrasse in Baar (Canton of Zug, Switzerland) and the high medieval Dalheim cemetery (North Rhine-Westphalia, Germany) were analyzed. Caries, periodontal condition, periapical lesions, antemortem tooth loss, and enamel hypoplasia were assessed in 654 teeth (993 observable loci) from 68 individuals (Baar: n = 36; Dalheim: n = 32). ResultsThe oral status of both populations was affected by age with higher values of tooth wear in advanced age individuals. High tooth wear values in both populations point towards the consumption of abrasive foods. Pronounced anterior tooth wear in Baar may also be due to non-masticatory tooth usage. Finally, possible nutritional deficiencies were hypothesized for the Baar population. A higher caries prevalence was observed in the Baar group, probably due to differences in carbohydrate intake. The oral conditions observed in the two studied populations exhibited several analogies, suggesting comparable lifestyles despite their separation in space and time. The only differences observed are related to the use of teeth as “tools” and are thus determined by behavioral choices rather than diverse socioeconomic factors. ConclusionsUsing multiple dental parameters to examine the oral health of premodern individuals can provide useful insights into the interactions between humans and their environment, from dietary patterns to paramasticatory activities.

The Evaluation of Energy Availability and Dietary Nutrient Intake of Sport Climbers at Different Climbing Levels

Proper nutrition is the basis for athletes' performances when competing or training. The increasing training volume accompanying the increase in advancement should go hand in hand with the appropriate supply of energy as well as macro and micronutrients. The diet of climbing representatives due to the desire to achieve a low body weight may be deficient in energy and micronutrients. Our study aimed to evaluate the differences in energy availability and nutrient intake of female and male sport climbers at different climbing levels. Anthropometric parameters and the resting metabolic rate were measured, the questionnaire about climbing grade and training hours was filled, and a 3-day food diary was fulfilled by 106 sport climbers. Based on the collected data, the energy availability as well as the macro- and micronutrient intake was calculated. Low energy availability (EA) was observed among both genders of sport climbing representatives. A significant difference between EA in various levels of advancement was found in the male group (p < 0.001). Differences in carbohydrate intake (g/kg/BW) between sexes were observed (p = 0.01). Differences in nutrients intake between climbing grade were found in both the female and male groups. In the group of female elite athletes, the adequate supply of most of the micronutrients can imply a high-quality diet despite the low calorie content. It is necessary to educate sport climbing representatives about the importance of proper nutrition as well as the consequences of insufficient energy intake.

Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults: A Randomized Controlled Trial

BackgroundIt is unclear whether moderate differences in dietary carbohydrate quantity and quality influence plasma FAs in the lipogenic pathway in healthy adults. ObjectivesWe investigated the effects of different carbohydrate quantities and quality on plasma palmitate concentrations (primary outcome) and other saturated and MUFAs in the lipogenic pathway. MethodsTwenty healthy participants were randomly assigned, and 18 (50% women; age: 22–72 y; BMI: 18.2–32.7 kg/m2 and BMI was measured in kg/m2) started the cross-over intervention. During each 3-wk period (separated by a 1-wk washout period), 3 diets were consumed (all foods provided) in random order: low-carbohydrate (LC) (38% energy (E) carbohydrates, 25–35 g fiber/d, 0% E added sugars); high-carbohydrate/high-fiber (HCF) (53% E carbohydrates, 25–35 g fiber/d, 0% E added sugars); and high-carbohydrate/high-sugar (HCS) (53% E carbohydrates, 19–21 g fiber/d, 15% E added sugars). Individual FAs were measured proportionally to total FAs by GC in plasma cholesteryl esters, phospholipids, and TGs. False discovery rate–adjusted repeated measures ANOVA [ANOVA-false discovery rate (FDR)] was used to compare outcomes. ResultsThe self-reported intakes of carbohydrates and added- and free sugars were; 30.6% E and 7.4% E in LC, 41.4% E and 6.9% E in HCF, and 45.7% E and 10.3% in HCS. Plasma palmitate did not differ between the diet periods (ANOVA FDR P > 0.43, n = 18). After HCS, myristate concentrations in cholesterol esters and phospholipids were ≥19% higher than LC and ≥22% higher than HCF (P = 0.005). After LC, palmitoleate in TG was 6% lower compared with HCF and 7% compared with HCS (P = 0.041). Body weight differed (≤0.75 kg) between diets before FDR correction. ConclusionsDifferent carbohydrate quantity and quality do not influence plasma palmitate concentrations after 3 wk in healthy Swedish adults, whereas myristate increased after the moderately higher intake of carbohydrate/high-sugar, but not carbohydrate/high-fiber. Whether plasma myristate is more responsive than palmitate to differences in carbohydrate intake requires further study, especially considering that participants deviated from the planned dietary targets. J Nutr 20XX;xx:xx–xx.This trial was registered at clinicaltrials.gov as NCT03295448.

Relationship Between Carbohydrate Intake (Quantity, Quality, and Time Eaten) and Mortality (Total, Cardiovascular, and Diabetes): Assessment of 2003-2014 National Health and Nutrition Examination Survey Participants.

In this study we investigated the association of the quantity, quality, and timing of carbohydrate intake with all-cause, cardiovascular disease (CVD), and diabetes mortality. This secondary data analysis included use of National Health and Nutrition Examination Survey (2003-2014) and National Death Index data from adults (n = 27,623) for examination of the association of total daily and differences in carbohydrate intake with mortality. Participants were categorized into four carbohydrate intake patterns based on the median values of daily high- and low-quality carbohydrate intake. The differences (Δ) in carbohydrate intake between dinner and breakfast were calculated (Δ = dinner - breakfast). Cox regression models were used. The participants who consumed more high-quality carbohydrates throughout the day had lower all-cause mortality risk (hazard ratio [HR] 0.88; 95% CI 0.79-0.99), whereas more daily intake of low-quality carbohydrates was related to greater all-cause mortality risk (HR 1.13; 95% CI: 1.01-1.26). Among participants whose daily high- and low-quality carbohydrate intake were both below the median, the participants who consumed more high-quality carbohydrates at dinner had lower CVD (HR 0.70; 95% CI 0.52-0.93) and all-cause mortality (HR 0.82; 95% CI 0.70-0.97) risk; an isocaloric substitution of 1 serving low-quality carbohydrates intake at dinner with high-quality reduced the CVD and all-cause mortality risks by 25% and 19%. There was greater diabetes mortality among the participants who consumed more low-quality carbohydrates at dinner (HR 1.78; 95% CI 1.02-3.11), although their daily high-quality carbohydrate intake was above the median. Consuming more low-quality carbohydrates at dinner was associated with greater diabetes mortality, whereas consuming more high-quality carbohydrates at dinner was associated with lower all-cause and CVD mortality irrespective of the total daily quantity and quality of carbohydrates.

Analisis Asupan Karbohidrat dan Lemak pada Dewasa Muda dengan Obesitas Sentral di Fakultas Kedokteran Universitas Riau

Central obesity is a state of the body characterized by the accumulation of excess fat in the abdominal area and is a component of the metabolic syndrome and plays an important role in the pathogenesis of cardiovascular disease and cancer. The main causes of central obesity are the wrong diet such as a diet high in fat and carbohydrates and low in fiber. The purpose of this study was to analyze carbohydrate and fat intake in young adults with central obesity. This research was an analytical study with a cross-sectional approach. The Sampling techniques used the purposive sampling method with a sample of 66 people consisting of 33 central obese people and 33 central non-obese people. The results of this study showed that the average consumption of carbohydrates in a day on central obesity is higher (341,74 g/day) than the consumption of carbohydrates in non-central obesity (263,26 g/day) and the average consumption of fat in a day on central obesity is higher (167.2 g/day) than the consumption of fats of non-central obesity (100,3 g/day). There was a significant difference in carbohydrate intake and fat intake between the group of young adults with central obesity and non-central obesity (p=0.000).

Glucose Awareness to Motivate and Enable Solutions (GAMES) in diabetes mellitus using flash glucose monitoring: A clinical programme.

This real-world observational clinical programme evaluated short and medium-term effects of intermittent flash glucose monitoring on HbA1c, glycaemic variability and lifestyle behavioural changes. Two first-generation Libre flash glucose monitoring sensors were provided 3-4months apart with a food, activity diary, user evaluation survey and treatment modification after each sensor wear. T-tests were used to compare glucose variables within each sensor (week 1 vs. week 2) and between sensors (1st sensor vs. 2nd sensor). EasyGV software was used to calculate glycaemic variability. From 42 type 1 diabetes and 120 type 2 diabetes participants, there was no statistically significant change in mean HbA1c for participants with type 1 diabetes at 3-4months after the 1st sensor but there was a statistically significant HbA1c reduction for participants with type 2 diabetes [-4mmol/mol (-0.4%), p=0.008], despite no statistically significant differences in carbohydrate intake, exercise frequency and duration. Greater reduction was seen in those with baseline HbA1c> 86mmol/mol (10%) in both type 1 [-12mmol/mol (-1.1%), p=0.009] and type 2 diabetes [-11mmol/mol (-1.0%), p=0.001). Both type 1 and type 2 diabetes showed improvements in Glucose Management Indicator and percentage time-above-range when comparing week 1 versus week 2 of the same sensor. Higher scan frequency resulted in improved glycaemic parameters and certain measures of glycaemic variability. The majority of participants (85%) agreed that flash glucose monitoring is a useful device but only 60% were keen to use it for daily monitoring. Constant feedback from flash glucose monitoring improves glycaemic parameters within the first week of wear. Intermittent use 3-4months apart resulted in greater improvements for those with higher baseline HbA1c.

Assessment of macronutrients consumption in the diet of adolescent school children in four seasons: a longitudinal study from an urban city in Pakistan

BackgroundA healthy diet in the adolescence period is essential for physical, mental, and immunological development. We aimed to assess macronutrient consumption in the diet of adolescent school children using 24 h recalls in four seasons of the year.MethodThis was a longitudinal study conducted from February 2014 to June 2015. The study population included 155 school children aged 7–14 years from an urban school in Karachi. 24HR recall was conducted on 4 random days of the 4 main seasons. A food composition table was developed where the weight, calories, carbohydrate, fat, and protein content of the food items were listed. Macronutrients quantification was calculated by using proportional weight from the food composition table. Food groups were also assigned to each food item including vegetables, fruits, grains, protein foods, dairy products, and oils.ResultsA total of 155 adolescent children aged between 7 and 14 years were approached. Out of the 155 preadolescents and adolescents, 150 (96.7%) agreed to participate. The mean (SD) age of the children was 11.31 (1.6) years, and 59% of all the children were males. Overall mean (SD) daily intake for all seasons was 195.31 (86.87) grams of carbohydrates, 94.77 (71.87) grams of proteins, and 55.87 (30.79) grams of fats. Carbohydrates formed 48.16%, protein 21.92%, and fat 29.93% of the total caloric intake. The mean (SD) daily caloric intake was 1517 (644) grams. Overall, the highest source of calories was from carbohydrate 781 (347) Kilocalories (Kcal), followed by fat 502 (277) Kcal and protein 379 (287). The Carbohydrate intake in 24 h was highest in the autumn; 212.81 (85.37), and there was a significant difference in carbohydrate intake in all seasons (p value 0.003). Consumption of discretionary food group was high (31.3%), and consumption of fruits and vegetables was low (29%).ConclusionThe study reports a suboptimal caloric intake of fewer than 2000 cal/day among the adolescents from school. The highest source of calories was from carbohydrates.The highest consumption of food was in autumn and the least in summer. Fruits and vegetable intake was low, and discretionary food intake was high.

Pengaruh konsultasi gizi terhadap asupan karbohidrat dan kadar gula darah pasien Diabetes Mellitus Tipe II di Poliklinik Endokrin RSUZA Banda Aceh

Background: Wasting is nutritional status in school children. In the community it is known as thin nutrition which is an important public health problem because it has a big impact. Thin nutrition can increase the risk of illness and death in children Diabetes Mellitus is a disorder of carbohydrate metabolism caused by a deficiency of insulin released by the pancreas gland both relative and absolute. In addressing the prevalence of Diabetes Mellitus in the Regional General Hospital dr. Zainoel Abidin Banda Aceh held nutritional consultations in outpatients and inpatients aimed at making changes to the knowledge, attitudes, and behavior of patients' eating patterns. In Aceh, in 2016 the number of Diabetes Mellitus patients was 29% and increased in 2017 by was 30%.Objectives: To determine the effect of nutritional consultation on carbohydrate intake and blood sugar levels in Type II Diabetes Mellitus patients.Methods: This type of research is descriptive analytic, sampling is done by purposive sampling and obtained 30 samples. This research was conducted in June 2017 at in Endocrine Polyclinic of RSUZA hospital Banda Aceh. The data taken are primary and secondary data. Data collection by interview using a questionnaire, food recall with interview techniques and examination of blood sugar levels before and after consultation. Data analysis uses T-Dependent Test (Paired Sample T-Test) with SPSS.Results: The results showed that there were significant differences in carbohydrate intake between before and after nutrition consultations were given in patients of Diabetes Mellitus Type II with a p-value= 0.001. Blood sugar level also shows the difference between after being given a nutrition consultation with a value of p-value= 0.000 in patients of Diabetes Mellitus Type II in the in Endocrine Clinic of RSUZA hospital, Banda Aceh.Conclusion: Nutrition consultation has a significant effect on carbohydrate reduction and blood sugar levels in patients with Diabetes Mellitus Type II in the Endocrine Polyclinic of RSUZA Banda Aceh. Keywords

Pengaruh Pemberian Konseling Gizi Terhadap Asupan Zat Gizi Dan Kadar Glukosa Darah Pada Pasien Diabetes Mellitus Tipe 2 Di Wilayah Kerja Puskesmas Motoling

Diabetes Mellitus is a group of heterogeneous disorders characterized by elevated blood glucose levels or hyperglycemia. Counseling to people with Diabetes Mellitus about nutrition and healthy lifestyle is a method to raise awareness of Diabetes Mellitus patients to change food intake so as to improve blood glucose levels. The purpose of this study is to determine the effect of nutrition counseling on nutrient intake and blood glucose levels in patients with type 2 Diabetes Mellitus in the work area of ​​Motoling Puskesmas. The research type is pre experiment design with one group pretest and posttest approach. The population in this study were 55 outpatient Diabetes Mellitus patients at Motoling Puskesmas, a sample of 23 outpatient Diabetes Mellitus Type 2 patients at Motoling Puskesmas. Nutrition counseling using media leaflets is given four times a month. Data Food intake was taken by using food recall 24 hours, data of glucose level of patient was taken by doing autocheck blood sugar test and for characteristic data of respondent using questioner. To determine the difference of glucose level with carbohydrate and fat intake before and after nutritional counseling was analyzed by using paired test of T test and Wilcoxon test. The results showed that there was a significant difference between carbohydrate intake before and after nutritional counseling (p = 0.002 &lt;α 0.05). Average carbohydrate intake before counseling 359.52 g and after counseling 290.09 g a decrease of 69.43 g. For fat intake showed no significant difference in carbohydrate intake before and after nutritional counseling (p = 0.009 &lt;α 0.05). Average fat intake before counseling 128.61 g and after counseling 75.04 g decreased 53.56 g. While blood glucose levels showed no significant difference in carbohydrate intake before and after nutritional counseling (p = 0.000 &lt;α 0.05). Mean blood glucose levels before counseling 255 mg / dl to 202.39 mg / dl decreased 52.60 mg / dl. Conclusion, there is a significant difference between nutrient intake and blood glucose levels in patients with Diabetes Mellitus type 2 in the work area of Motoling Puskesmas.

Temperature dependence of predation stress and the nutritional ecology of a generalist herbivore.

Prey at risk of predation may experience stress and respond physiologically by altering their metabolic rates. Theory predicts that such physiological changes should alter prey nutrient demands from N-rich to C-rich macronutrients and shift the balance between maintenance and growth/reproduction. Theory further suggests that for ectotherms, temperature stands to exacerbate this stress. Yet, the interactive effects of predation stress and temperature stress on diet, metabolism, and survival of ectotherms are not well known. This knowledge gap was addressed with a laboratory study in which wild juvenile grasshoppers were collected, assigned to one of three groups, and raised at three different temperatures. All grasshoppers had access to equal quantities of two diets composed of opposite carbohydrate:protein ratios. Half of the individuals in each temperature group were exposed to predation risk cues from spider predators, while the other half were kept in risk free conditions. Grasshoppers consumed more carbohydrates when exposed to predation risk, but consumption favored greater protein intake as temperature increased. Moreover, the difference in carbohydrate intake between risk cue and risk free treatments diminished as temperature increased. Furthermore, variability between individual consumption patterns both within and between treatments decreased markedly as temperature increased, suggesting that higher temperatures promote more consistent individual consumption behaviors. Grasshoppers grew faster and larger as temperature increased, which translated into higher survival rates at higher temperatures. Warmer grasshoppers also did not alter their metabolic rates in response to predation risk cues, in contrast to colder grasshoppers. Digestive efficiency increased with temperature as well -- further indicating that lower temperatures were much more stressful than higher temperatures for grasshoppers. The study shows that physiological responses of ectothermic herbivores to predation stress are highly plastic and temperature dependent, with higher temperatures promoting increased protein intake, growth, development, survival, and digestive efficiency relative to colder temperatures. These findings help to reconcile why dietary responses (proportion of protein vs. carbohydrate intake) to predation stress may vary among different prey taxa studied previously.

Macronutrient Composition or Social Determinants? Impact on Infant Outcomes With Gestational Diabetes Mellitus.

The purpose of this study was to examine, through a randomized, controlled trial, the effects of a maternal carbohydrate-restricted diet on maternal and infant outcomes in gestational diabetes mellitus (GDM). Women diagnosed with GDM were randomly allocated into one of two groups: an intervention group that was placed on a lower-carbohydrate diet (35–40% of total calories) or a control group that was placed on the usual pregnancy diet (50–55% carbohydrate). A convenience sample of participants diagnosed with GDM (ages 18–45 years) was recruited from two different sites: one urban and low-income and the other suburban and more affluent. Individual face-to-face diet instruction occurred with certified diabetes educators at both sites. Participants tested their blood glucose four times daily. Specific socioeconomic status indicators included enrollment in the Supplemental Nutrition Program for Women, Infants and Children or Medicaid-funded health insurance, as well as cross-sectional census data. All analyses were based on an intention to treat. Although there were no differences found between the lower-carbohydrate and usual-care diets in terms of blood glucose or maternal-infant outcomes, there were significant differences noted between the two sites. There was a lower mean postprandial blood glucose (100.59 ± 7.3 mg/dL) at the suburban site compared to the urban site (116.3 ± 15 mg/dL) (P <0.01), even though there was no difference in carbohydrate intake. There were increased amounts of protein and fat consumed at the suburban site (P <0.01), as well as lower infant complications (P <0.01). Further research is needed to determine whether these disparities in outcomes were the result of macronutrient proportions or environmental conditions.

Changing Dietary Calcium-Phosphorus Level and Cereal Source Selectively Alters Abundance of Bacteria and Metabolites in the Upper Gastrointestinal Tracts of Weaned Pigs

Several dietary ingredients may affect the bacterial community structure and metabolism in the porcine gut and may therefore influence animals' health and performance. This study investigated the effects of cereal source and calcium-phosphorus (CaP) level in the diet on bacterial microbiota and metabolites, nutrient intake, and gut environment in weaned pigs. Pigs (n=8/treatment) were fed wheat-barley- or corn-based diets with an adequate or high CaP level for 14 days. Effects on microbiota in the stomach, ileum, and midcolon were assessed using quantitative PCR. Data showed that Enterobacteriaceae, Campylobacter spp., and Helicobacter spp., which all contain highly immune reactive lipopolysaccharide (LPS), were abundant at all gut sites. Diet effects on bacteria and metabolites were moderate and occurred mainly in the upper gut, whereas no effects on bacteria, fermentation products, and LPS could be observed in the colon. Differences in carbohydrate intake with corn versus wheat-barley diets selectively stimulated Bifidobacterium in the stomach and ileum. There was a growth advantage for a few bacterial groups in the stomach and ileum of pigs fed the high versus adequate CaP level (i.e., gastric Enterobacteriaceae and ileal Enterococcus, Bacteroides-Prevotella-Porphyromonas, and Campylobacter). Interestingly, gastrointestinal pH was not affected by dietary CaP level. The present findings demonstrate the stability of the bacterial community and gut environment toward dietary changes even in young pigs. The results on stimulation of gastric and ileal Bifidobacterium by corn diets may be employed in nutritional strategies to support gut health after weaning.

Intervensi biskuit tempe kurma bagi peningkatan status gizi balita penderita tuberkulosis

Background: Weight gain as an indicator of nutritional status during tuberculosis drugs management has a significant relationship with the rapid conversion of sputum smear, low incidence of relapse and duration of anti tuberculosis drugs in patients with tuberculosis. Low intake of food in patient suffering from an infectious disease is caused by the emergence of anorexia, nausea, vomiting, and increased body temperature. Inadequate nutrient intake affects the immune system, lower resistance to infection and slow healing resulting progressive tuberculosis (TB).Objective: To assess the effect of tempeh dates biscuit consumption on the change of nutritional status of tuberculosis preschoolers patients.Method: A quasi-experimental design towards 52 under five children with TB status and who were underweight was done in all sub-districts at Depok City. There were three groups participated in the study i.e tempeh dates biscuits as intervention group, and two groups of control (tempeh and placebo biscuits). The nutritional status of subjects was assessed each biweekly by giving daily 50 grams of biscuits within four weeks. Data analysis was using paired t-test and Anova.Results: There was greatest weight gain in a subject who received tempeh dates biscuit by 0.5 kg and largest height improvement in the tempeh biscuits group by 1.8 cm. Weight, height and z-score weight/age had significant differences in the three groups at the end of the study. There were significant differences in carbohydrate intake in the intervention group at pre and post-intervention. The tempeh biscuits group had different levels of mothers’ knowledge on nutrition and TB at the end of the study.Conclusion: Tempeh dates biscuit can be recommended as an alternative supplementation feeding program for TB and non-TB under five children with underweight status.

Plasma Arginine Levels and Blood Glucose Control in Very Preterm Infants Receiving 2 Different Parenteral Nutrition Regimens

Improving parenteral nutrition (PN) amino acid (AA) intake in very preterm infants is associated with less hyperglycemia. AAs stimulate newborn insulin secretion with arginine, demonstrating a specific effect. We hypothesized that low arginine levels would be associated with increased insulin-treated hyperglycemia and higher mean daily blood glucose levels in very preterm infants. We performed a secondary analysis on previous study data comparing high-protein/calorie PN (HPC-PN) and control groups in infants <29 weeks' gestation. Infants were substratified (within original groups) according to high (highARG) and low (lowARG) plasma arginine levels on days 8-10 using a reference population-derived threshold for high/low arginine (57 µmol/L). Daily protein, arginine, carbohydrate intake, mean daily blood glucose, and insulin treatment data from the first 15 days of life were collected. Control group infants (n = 60) were stratified into lowARG (n = 41) and highARG (n = 19) groups. There were no differences in basic demographic data or carbohydrate intake. LowARG infants had higher mean daily blood glucose levels ( P .05) and a trend to more insulin treatment on days 610. HPC-PN group infants (n = 55) were stratified into lowARG (n = 33) and highARG (n = 22) GROUPS. LowARG infants had lower gestation and birth weight and were sicker than highARG infants. There were no differences in carbohydrate intake. LowARG infants had higher mean daily blood glucose levels (p .01) and more insulin treatment (p .01) on days 15 and 610. Insulin-treated hyperglycemia was also associated with low plasma glutamine levels. Low plasma arginine levels (≤57 µmol/L) in very preterm infants are associated with poorer blood glucose control.

Effects of neuromedin-β on caloric compensation, eating behaviours and habitual food intake

We have previously shown that a missense mutation (p.P73T) located in the neuromedin-β gene, a satiety peptide, was associated with higher levels of disinhibition, susceptibility to hunger, and body weight gain over time. In this study we compare caloric compensation, eating behaviour traits, food intake and adiposity between premenopausal women with (T73T) and without (P73P) mutation. Subjects ( N = 153) were screened to find homozygous women (T73T) that were matched for age, BMI and use of oral contraceptives with 7 women (P73P) not carrying the mutation. Eating behaviour traits were assessed with the Three-Factors Eating Questionnaire and habitual dietary intakes with a 3-day dietary record. A randomized single-blind cross-over design was used to test the effect of p.P73T on caloric compensation. We measured appetite sensations and ad libitum dietary intake following two different energy preloads. We found no difference in eating behaviour traits, adiposity, appetite sensations, ad libitum dietary intake and caloric compensation. However, T73T women had lower habitual energy and carbohydrate intakes than P73P. Differences in carbohydrate intakes disappeared when expressed in percentage of energy. These results suggest that the neuromedin-β p.P73T mutation modulates energy intake without effects on macronutrient. A lack of power resulting from our difficulty to recruit enough T73T women precludes any definitive conclusion regarding the impact of this mutation on caloric compensation.

Evaluation of Energy and Nutrient Intake as well as Dietary Behaviors in Elementary School and Middle School Students Residing in Chungnam according to Breakfast Eating Status

The purpose of this study was to evaluate the dietary behaviors as well as energy and nutrient intake in elementary and middle school students according to breakfast eating status. The survey was conducted using questionnaires and dietary records among 191 elementary school students and 280 middle school students residing in Chungnam. The subjects were divided into two groups according to frequency of eating breakfast: breakfast skipping (frequency of eating breakfast under 4 times/week) and breakfast eating (frequency of eating breakfast over 5 times/week). The rate of breakfast skipping was 27.2% for the elementary school students and 31.1% for the middle school students. The breakfast skipping group had a significantly lower frequency of having dinner, a lower proportion of eating at regular meal times, and a significantly higher frequency of leaving food after meals than the breakfast eating group for both elementary and middle school students. In the case of the elementary students, there was a significant difference in carbohydrate intake between the two groups. In the case of the middle school students, the intakes of energy, protein, carbohydrate, dietary fiber, vitamin A, vitamin B2, niacin, vitamin B6, folate, vitamin C, Ca, and Fe in the breakfast skipping group were significantly lower than those in the breakfast eating group. These results show that nutrient deficiencies among breakfast skipping individuals cannot be compensated for at the other meals during the day in middle school-aged adolescents whose nutrient requirements are high for growth. Therefore, in support of proper dietary management, it is necessary to promote and support breakfast eating in adolescents.

Sex-specific differences in nutrient regulation in a capital breeding caterpillar, Spodoptera litura (Fabricius)

Nutrient requirements by male and female insects are likely to differ, but relatively little is known regarding how sexes differ in their regulation of macronutrient acquisition. The present study reports the results from a laboratory experiment in which behavioural and physiological components of nutrient regulation were compared between male and female caterpillars of Spodoptera litura (Fabricius). When provided with choices between two nutritionally complementary foods (one is a protein-biased diet and the other a carbohydrate-biased diet), both males and females adjusted their food selection to defend an intake target. However, the composition of diet preferred by the two differed, with females selecting significantly more protein than males with no difference in carbohydrate intake between the two. When confined to single diets with varying mixtures of protein and carbohydrate [P:C ratios, expressed as the percentage of diet by dry mass: protein 42%:carbohydrate 0% (p42:c0), p35:c7, p28:c14, p21:c21, p14:c28, p7:c35], females consumed more macronutrients than did males across on all P:C diets except the extremely carbohydrate-biased diet (p7:c35). Under both choice and no-choice feeding condition, such sex differences in nutrient intake were not expressed until late in the feeding stage of the final stadium. Sexes also differed in post-ingestive utilization of ingested nutrients. Females utilized ingested protein for body growth with greater efficiency compared to males, presumably reflecting provisioning their adult needs for protein to develop eggs, whereas males were more efficient at depositing lipids from carbohydrate intake than females.

Comparison of Energy Nutrient and Fat Intake between the Hypertensive and Normotensive Male Workers

Objectives: The purpose of this study was to investigate the difference in nutrient intake between normotensive workers and hypertensive workers to obtain basic data for developing a program of effective hypertension care at work. Methods: The subjects were 338 male workers. We measured physical data by medical examination and collected lifestyle data by questionnaire survey. Dietary intakes were collected using a food frequency questionnaire. We classified the subjects into normal, prehypertension, and hypertension groups, and compared the results of age, body mass index (BMI), blood pressure (BP), lifestyles and energy nutrients and lipids intake. Results: There were significant differences in both weight and BMI between the hypertension group and the other two groups (p<0.05). The smoking levels of the prehypertension group and hypertension group were significantly higher than that of the normal group (p<0.05). The three groups also showed significant differences in drinking amount (p<0.05). There were significant differences in carbohydrate and protein intakes and the ratio of carbohydrate, protein, and fat intake (p<0.05). Conclusion: In this study, there was a significant difference in carbohydrate intake between normotensive and hypertensive workers, and the intake of energy nutrients and fatty acids in the prehypertension group and hypertension groups was unbalanced. Therefore, early diagnosis of workers with hypertension and prehypertension is necessary to improve lifestyles particularly food habit.

Alterations in fuel selection and voluntary food intake in response to isoenergetic manipulation of glycogen stores in humans

This study investigated the relative importance of alterations in carbohydrate intake or oxidation as mechanisms for rectifying extreme perturbations of glycogen stores. Six lean men were studied on three occasions in which a stabilization period (days 1 and 2) was immediately followed by whole-body indirect calorimetry (days 3-5). Glycogen stores were manipulated on days 3 and 4 by using isoenergetic diets providing carbohydrate at 79% (HC), 48% (MC), or 9% (LC) of energy. Free access to MC meals and snacks was allowed on days 5 and 6 outside the calorimeter. The manipulations caused large alterations in glycogen stores (HC, +206 g; MC, +132 g; LC, -121 g; HC vs LC, 327 g), but subsequent voluntary food intake was very similar across treatments (HC, 18.2 MJ/36 h; MC, 17.7 MJ/36 h; LC, 18.1 MJ/36 h, NS). Over days 3-5 the average difference in carbohydrate intake (HC vs LC) was 16.1 MJ (1010 g), but balances differed by only 1.7 MJ (110 g) because of autoregulatory changes in carbohydrate oxidation. These were the only significant mechanisms for reestablishing carbohydrate balance.

Cholecystokinin-induced secretion and synthesis of amylase and cationic trypsinogen by pancreatic acini isolated from rats given an ethanol diet

Effects of chronic alcohol intake on secretion and synthesis of amylase and cationic trypsinogen (CT) were studied with pancreatic acini isolated from male Sprague-Dawley rats fed a Lieber-DeCarli ethanol or control diet for 30 days. Pancreatic acini were incubated in a media containing increasing concentrations of cholecystokinin octapeptide (CCK-8: 0-1000pM) followed by addition of [ 3H]leucine. Amylase and CT secreted in the media and those labeled in acini were quantitated. Basal and CCK-stimulated secretion of CT was not different in alcoholic and control groups. On the other hand, a dose-response curve of CCK-stimulated amylase secretion from alcoholic acini was markedly reduced with both basal and maximal secretion decreased to only 40% of controls. Basal incorporation of [ 3H]leucine into amylase was reduced by 70% in alcoholic acini compared to controls while that into CT was not different in the two groups. CCK-8 exhibited a biphasic effect on [ 3H]leucine incorporation into both enzymes in alcoholic acini: low concentrations of CCK-8 (<100pM) increased the incorporation whereas high concentrations (>100pM) decreased it. However, in control acini, CCK-8 induced progressive suppression of the incorporation into these enzymes, the pattern of which was similar to that previously observed in fasted rats (Am. J. Physiol. 241:G116–G112, 1981). This difference in the response pattern resulted in significantly higher rates of CCK-8 induced incorporation into CT in alcoholic acini. These results suggest that the differences observed may possibly be attributable not only to alcohol intake but also to the differences in carbohydrate intake and in temporal patterns of diet consumption.