Diethylene Triamine Penta Methylene Phosphonic Research Articles

Biodistribution of 68Ga-DTPMP as a potential bone-seeking imaging agent in normal rats and rats with experimental model of bone callus

Bone metastases are common in advanced stages of various cancers. Positron emission tomography (PET) with radiotracers based on phosphonates and gallium-68 is a promising method of bone metastases detection. In this work a new complex based on diethylene triamine pentamethylene phosphonate (DTPMP) labeled with 68Ga was developed and its biodistribution in normal Wistar rats and rats with experimental model of bone callus was studied. The biodistribution studies in normal rats revealed high skeletal uptake of 68Ga-DTPMP (up to 1.45 %ID/g in femur) with rapid blood clearance and minimal uptake in any other major organs, except kidneys. In rats with experimental model of bone callus the accumulation of activity in bones and soft organs and tissues was slightly lower as compared with normal rats. The amount of 68Ga-DTPMP in femur with bone callus was higher than in non-lesion bones and reached 1.90 %ID/g at 2 h p.i. Therefore, 68Ga-DTPMP could be a promising radiotracer for bone tumors imaging and could be a valuable alternative to 18F-FDG and 18F-NaF for PET centers without an onsite cyclotron.

Effects of Phosphonate Structures on Brine–Biotite Interactions under Subsurface Relevant Conditions

Phosphonates have been widely used as scale inhibitors in energy-related subsurface operations, where their performance is greatly affected by interactions with rocks and minerals. However, information about commonly used phosphonate scale inhibitor–shale interactions is limited. In this study, using Fe-bearing mica (biotite) as a model phyllosilicate mineral, the effects of three common phosphonates, namely, iminodi(methylene)phosphonate (IDMP), nitrilotris(methylene)phosphonate (NTMP), and diethylenetriaminepenta(methylene)phosphonate (DTPMP), were studied at 95 °C and 102 atm CO2. During the experiments (0–70 h), IDMP remained stable, while NTMP and DTPMP were degraded and released phosphate, formate, and new phosphonates with smaller molecular weights. As a result of the differences in complexation capability, IDMP, with the fewest phosphonate functional groups, promoted biotite dissolution mainly through surface complexation and DTPMP, with the most functional groups, promoted biotite dissolution mai...

Effect of DTPMPA on Bamboo Kraft Pulping

As a cooking additive, the impact of Diethylene Triamine Penta Methylene Phosphonic Acid (DTPMPA) on bamboo kraft pulping was studied. The effect of DTPMPA dosage at different maximum cooking temperature was discussed. The results showed that the cooking aids DTPMPA added in bamboo kraft pulping was able to reduce K value of pulp, improve the screened stock yield and brightness and reduce the alkali charge. The optimized bamboo kraft pulping conditions are: DTPMPA dosage 0.3%, alkali charge 17%, when sulfidity was 20%, maximum cooking temperature was 160°C and time at maximum temperature was 90min. Under the conditions of cooking, the screened yield is 41.53%, the K value is 15.4 and the bamboo pulp brightness is 26.8%.

Study on Bamboo Kraft Pulping with DTPMPA

DTPMPA (Diethylene Triamine Penta Methylene Phosphonic Acid) was used as cooking additive in Bamboo pulping. The effect of cooking parameters such as alkali charge, maximum cooking temperature, and time at maximum temperature on bamboo kraft pulping adding additive Diethylene Triamine Penta Methylene Phosphonic Acid was studied. The results show that the optimized bamboo kraft pulping conditions are: alkali charge 17%, maximum cooking temperature 162°C, and time at maximum temperature 60min when DTPMPA dosage is 0.4%. On the optimized conditions of cooking, the highest screened bamboo pulp yield 49.52%, the kappa number of bamboo pulp is 24.68, residual alkali in kraft waste liquor 3.62g/L .

Study on DTPMPA as Cooking Additive in Bamboo Pulping

The application of chelating agents DTPMPA (Diethylene Triamine Penta Methylene Phosphonic Acid) as cooking aids in kraft pulping of bamboo was researched. The effect of DTPMPA dosage at different alkali charge was discussed. The results showed that the cooking aids DTPMPA added in bamboo kraft pulping was able to reduce K value of pulp, improve the screened stock yield and brightness and reduce the alkali charge. The optimized bamboo kraft pulping conditions are: DTPMPA dosage 0.4%, alkali charge 19%, when sulfidity was 20%, maximum cooking temperature was 165°C and time at maximum temperature was 90min. Under optimized conditions of cooking, the screened bamboo pulp yield is higher, the K value is lower and the bamboo pulp brightness is higher.

Application of Chelating Agents as Cooking Aids in Bamboo Pulping

The effect of chelating agents Diethylene Triamine Penta Methylene Phosphonic Acid in bamboo kraft cooking was studied. The results show that the bamboo pulp yield was 49.52% when DTPMPA dosage is 0.4%, at the same time the Kappa number was lower. With the increasing of DTPMPA dosage in bamboo kraft pulping, the bamboo pulp strength was increased.

Separations of lanthanides and actinides using novel hybrid ion exchange materials, M(IV) phosphonates

Zirconium diethylene triamine pentamethylene phosphonate and titanium diethylene triamine pentamethylene phosphonate, novel hybrid cation exchange materials of the class of tetravalent metal acid salts, synthesized by sol-gel method has been characterized by spectroscopy and thermal analysis. Distribution coefficient and breakthrough capacity for La3+, Ce3+, Pr3+, Nd3+, Sm3+ (lanthanides) and Th4+, UO22+ (actinides) have been studied. Based on the differential affinity/selectivity and elution behavior of various metal ions, a few binary and ternary metal ion separations have been carried out.

The Inhibition Effect of Corrosion of Carbon Steel in Seawater by Diethylene Triamine Pentamethylene Phosphonic Acid and Al3+ System

The inhibition of the corrosion of carbon steel in seawater by diethylene triamine pentamethylene phosphonic acid (DTPMP) and Al 3+ has been investigated using weight loss and electrochemical measurements. The results show that 65% inhibition efficiency is achieved with binary system consisting of 250 ppm of DTPMP and 50 ppm of Al 3+ . Polarization curves indicate that the system is a mixed inhibitor. The surface morphology of the metal surface is examined using the scanning electron microscope.

Application of Diethylene Triamine Penta Methylene Phosphonic Acid in Bamboo Pulping

The effect of Diethylene Triamine Penta Methylene Phosphonic Acid in bamboo kraft cooking was studied. The results show that the bamboo pulp properties are optimal when DTPMPA dosage is 0.4%. The optimal properties are as follows: the kappa number is 16.4, brightness is 37.8%, and the screened yield is 41.9%.

Application of a Novel Hybrid Cation Exchange Material in Metal Ion Separations

A novel hybrid cation exchange material of the class of tetravalent metal acid (TMA) salt, titanium diethylene triamine pentamethylene phosphonate (TiDETPMP) has been synthesized by the sol gel method. The material has been analyzed by spectroscopy and thermal methods. Physico-chemical and ion exchange characteristics have also been studied. The distribution coefficient (K d ) has been determined in aqueous as well as various electrolyte media/concentrations for Co2+, Ni2+, Cu2+, Zn2+ (transition metal ions) and Cd2+, Hg2+, Pb2+, Bi3+ (heavy metal ions) using TiDETPMP. Based on the differential affinity/selectivity, the breakthrough capacity (BTC) and elution behavior of various metal ions towards TiDETPMP, a few binary and ternary metal ions separations have been carried out.

Synthesis, characterization and ion exchange characteristics of a novel hybrid ion exchange material

In the present study, zirconium diethylene triamine pentamethylene phosphonate (ZrDETPMP), a hybrid ion exchanger of the class of tetravalent metal acid (TMA) salt, has been synthesized by soft chemistry route, sol-gel method. The material was characterized for elemental analysis (ICPOES and CHN analyzer), thermal analysis (TGA), spectral analysis (FT-IR), X-ray diffraction and SEM. Chemical resistivity of the material was assessed in various media (acids, bases and organic solvents). Ion exchange capacity was determined and the effect of calcination on ion exchange capacity (IEC) was studied. The distribution behaviour (Kd) in different electrolyte media/concentrations, breakthrough capacity and elution behaviour of metal ions La3+, Ce3+, Pr3+, Nd3+, Sm3+ and Th4+ were studied and discussed.

Corrosion Inhibition by Sodium Gluconate‐Zn2+‐DTPMP System

The inhibition efficiency of a phosphonic acid, Diethylene Triamine Pentamethylene Phosphonic acid (DTPMP) in controlling corrosion of carbon steel immersed in an aqueous solution containing 60 ppm of Cl- has been evaluated by weight loss method in the absence and presence of Zn2+. The formulation consisting of DTPMP and Zn2+ has excellent inhibition efficiency (IE). A synergistic effect is noticed between Zn2+ and DTPMP. Addition of sodium gluconate (SG) enhances the IE of Zn2+ and DTPMP system. The DTPMP‐Zn2+‐SG system function as a mixed inhibitor as revealed by polarization study. AC impedance spectrum, optical and atomic force micrographs reveal the formation of a protective film on the metal surface. FTIR spectra reveal that the protective film consists of Fe2+‐DTPMP complex, Fe2+‐SG complex and Zn(OH)2.

Effect of phosphonate inhibitors on calcite nucleation kinetics as a function of temperature using light scattering in an autoclave

Phosphonates are some of the more popular inhibitors used in the oil industry to prevent formation of calcite scale. Only recently has it been shown that compounds with a direct P-C bond are forming naturally. The effect of phosphonate on calcite precipitation kinetics was studied using a Hastelloy autoclave fitted with sapphire windows so that light scattering measurements could be made in situ. As temperature increased from 25° to 200°C the induction time for calcite nucleation following CO 2 degassing decreased from more than an hour to a few minutes. The ability of chemical inhibitors (phosphonates) to delay nucleation also decreased with increasing temperature. One of the inhibitors, diethylenetriamine-pentamethylenephosphonate (DETPMP), was able to disperse the calcite precipitate, when used in concentrations sufficient to precipitate “calcium phosphonate”. It is still not clear whether phosphonates affect calcite precipitation kinetics by monolayer adsorption. or by surface precipitation.