Dietary Regulation Research Articles

'The god of criminals is their belly': diet, prisoner health, and prison medical officers in mid-nineteenth-century English and Irish prisons.

Existing scholarship on prison diets has emphasised the role of food and its restriction as a key aspect of the deterrent system of prison discipline introduced in the 1860s. Here we suggest that a strong emphasis was placed on dietary regulation after the establishment of the reformist, but also 'testing', separate system of confinement in the mid-nineteenth century. While the impact of diet on the physical health of prisoners was a major concern, we argue that the psychological impact of food was also stressed, and some prison administrators and doctors argued that diet had an important protective function in preserving inmates' mental wellbeing. Drawing on a wide range of prison archives and official reports, this article explores the crucial role of prison medical officers in England and Ireland in implementing prison dietaries. It highlights the importance and high level of individual adaptations to dietary scales laid down centrally, as a means of utilising diet as a tool of discipline or as an intervention to improve prisoners' health. It examines the forays of some prison doctors into dietary experiments, as they investigated the impact of different dietaries or made more quotidian adjustments to food intake, based on local conditions and food supplies. The article concludes that, despite central policies geared to establishing uniformity and interest in new scientific discourses on nutrition, a wide range of practices were pursued in individual prisons, mostly shaped by practical rather than scientific factors, with many prison medical officers asserting their autonomy in making dietary adjustments.

GERMINATED BLACK RICE (GEMAR) FUNCTIONAL BEVERAGE POWDER: A POTENTIAL ANTIOXIDANT FOR MANAGING DIABETES MELLITUS

Background Diabetes mellitus (DM) is a degenerative disease and a leading global cause of death, often linked to increased oxidative stress and free radicals. Prolonged DM can lead to various complications, including kidney issues, heart problems, vision impairment, and more. Dietary regulation is a recommended approach to managing DM. GEMAR beverage powder, derived from germinated black rice and mung bean, holds the potential as a source of antioxidants and is beneficial for individuals with DM due to its rich phytochemical content. Objective This study aims to determine the yield and antioxidant activity of GEMAR powder beverage as a therapy for DM. Methods This is a quantitative research study employing a true experimental design, which will be analyzed descriptively. The ingredients GEMAR beverage powder germinated black rice, germinated mung bean, tempeh, red spinach, skimmed milk, soy protein isolate, and maltodextrin. The GEMAR beverage powder production includes sorting, mixing, roasting, drying, milling, and filtration stages. The GEMAR beverage yield value was obtained by comparing the final powder weight and the initial powder weight. Analysis of the antioxidant activity of GEMAR beverage powder using the DPPH method. Results The yield of GEMAR beverage powder was 41,6% and the antioxidant activity of GEMAR powder beverage was 24,30±0,07%. Conclusion This study concluded that GEMAR beverage powder is a functional beverage that has antioxidant activity and has the potential to be used as a therapy for DM. Keywords: antioxidants; functional beverages; black rice; diabetes mellitus.

Abstract WP251: Dietary Methionine and Homocysteine Level Interaction and Recurrent Stroke

Background: The folate one-carbon metabolism pathway (FOCM) provides vital one-carbon units for epigenetic regulation. Genetic variants in FOCM genes may affect methionine metabolism. Elevated circulating homocysteine (Hcy), a FOCM byproduct, is linked to increased stroke risk. However, the protective effects of dietary regulation of methionine and Hcy levels against recurrent stroke are uncertain. Objective: To investigate dietary methionine (METH) and its interaction with post-methionine load Hcy levels (POST) with recurrent stroke risk; to assess if genetically determined POST and its interaction with METH predict recurrent stroke risk. Methods: We utilized the Vitamin Intervention for Stroke Prevention (VISP) trial to estimate hazards ratios of METH and its interaction with POST on recurrent stroke with a Cox proportional hazards model. We also generated a POST polygenic risk score (PRS) with ridge regression using previously identified polymorphisms, located within ALDH1L1, CPS1, GNMT, and PSPH, as indicators of FOCM function. Results: The participants (n = 2,100; 64% men) had a mean (SD) age of 67 (11) years. Ancestry consisted of 82% European, 12% African, and 5.7% Other. A small portion of participants had missing POST values (7.3%). Clinical POST (HR 1.02; 95%CI 0.98, 1.06) and its interaction with METH (HR 0.99; 95% CI 0.97, 1.01) were not associated with recurrent stroke risk. Similarly, there was no significant relationship observed between PRS POST (HR 0.96; 95%CI 0.80, 1.15) and its interaction with METH (HR 1.02; 95% CI 0.94, 1.10). Conclusion: Dietary methionine and post-methionine load Hcy levels neither interact nor predict recurrent stroke risk. Our PRS approach showed similar negative findings. The relationship of the FOCM and recurrent stroke risk may lie in epigenetics.

Calorie Tracking: A Mobile Application for Tracking Eating Patterns and Intake

A balanced regular calorie intake along with a good eating rules is an important factor to fullfill a healthy lifestyle and diet. Both are the main keys to preventing non-communicable diseases (NCDs) which are the largest contributors to world deaths. The effects produced through dietary regulation and calorie intake ideally will affect to the long term, so that consistency and adequate supporting media are needed. Judging from the time scale, action is needed since in, Early action is needed, especially for students who are in the transition period to maturity and independence. Technological developments in the digital era can be used to produce problem solutions ranging from fundamental aspects. Students themselves are familiar with the concept of the calorie tracker application (Craker) even though the majority have never used it. The purpose of this paper is to design the Craker application as a form of solution to regulate diet and calorie intake by applying the theory of human and computer interaction. The result of making this application is to monitor the number of calories consumed by knowing the number of calories in and out so that it is balanced according to the recommendations given based on the user’s profile, for the calorie tracker application we can divide it into three types of calorie tracker applications: web, mobile, and physical.

Medicine Constitution Intervention Combined with "Three-in-One" Treatment in Elderly Patients with Atherosclerotic Cardiovascular and Cerebrovascular Diseases

Objectives: The aim of this study was to evaluate the effectiveness of an intervention that combines Traditional Chinese Medicine (TCM) constitution identification and TCM health management with the "Three-in-One" community prevention and treatment model in managing atherosclerotic cardiovascular and cerebrovascular diseases in elderly patients. Methods: In this retrospective multicenter study, the medical records of 206 outpatient participants diagnosed with atherosclerotic cardiovascular and cerebrovascular diseases from June 2022 to June 2023 were reviewed. Participants were divided into 2 groups. Among participants, 104 (the control group) received instructions on adjusting medications and general health education. The other 102 (the intervention group) underwent TCM constitution identification and health management, which included psychological conditioning, dietary regulation, lifestyle adjustment, and physical exercise. Each intervention period lasted for 52 weeks, constituting one treatment course. Results: No notable improvements were identified in the changes to constitutional elements across both groups (p > .05). Both the treatment and control rates demonstrated significant improvement in both the intervention and control groups (p < .05). Conclusion: The combination of TCM constitution identification, TCM health management, and the Three-in-One treatment model showed promising results in managing atherosclerotic cardiovascular and cerebrovascular diseases in elderly patients.

Development on Mathematical Models of Type 2 Diabetes Mellitus (DM) in Individuals with A Genetic History

Diabetes Mellitus (DM) type 2 is one type of DM that is suffered by many DM sufferers. Type 2 DM can pass on to its offspring so it is necessary to prevent the emergence of type 2 DM. Prevention can be done such as exercise, weight loss, and dietary regulation. This study is a development of previous research with a primary focus on individuals who have a genetic history of having suffered from type 2 DM and it is recommended to choose one of the three prevention parameters involved. The next model development is to find the free equilibrium point values of DM type 2 and DM type 2 and the model will be analyzed for stability at the equilibrium point. The analysis of the basic reproduction number (R0) using the next generation matrix yielded the following values for each assumption: 0.1599; 0.1586; 0.1590; and 0.1582. Weight loss factors were discovered to play a significant influence in preventing type 2 diabetes among the three parameters studied.

Iron deficiency anemia: a critical review on iron absorption, supplementation and its influence on gut microbiota.

Iron deficiency anemia (IDA) caused by micronutrient iron deficiency has attracted global attention due to its adverse health effects. The regulation of iron uptake and metabolism is finely controlled by various transporters and hormones in the body. Dietary iron intake and regulation are essential in maintaining human health and iron requirements. The review aims to investigate literature concerning dietary iron intake and systemic regulation. Besides, recent IDA treatment and dietary iron supplementation are discussed. Considering the importance of the gut microbiome, the interaction between bacteria and micronutrient iron in the gut is also a focus of this review. The iron absorption efficiency varies considerably according to iron type and dietary factors. Iron fortification remains the cost-effective strategy, although challenges exist in developing suitable iron fortificants and food vehicles regarding bioavailability and acceptability. Iron deficiency may alter the microbiome structure and promote the growth of pathogenic bacteria in the gut, affecting immune balance and human health.

Review of Dietary Supplement Regulation

Review of Dietary Supplement Regulation

Influence of different amino acid scoring patterns on the protein quality of field peas

Pea (Pisum sativum L.) is a nutritious pulse crop and a significant plant-based protein source. Its amino acid composition and protein digestibility influence its nutritional quality. Although different guidelines for protein content claims exist in North America, recommended patterns by FAO/WHO can estimate protein quality for dietary assessment. This study’s primary objective is to examine how adopting the new FAO/WHO recommendations affects the protein quality and protein content claims of field peas, using in vitro methods, and to assess the potential impact on consumer food choices. This work evaluated the amino acid score (AAS) and in vitro protein digestibility (IVPD) to assess pea protein quality. The effect of different amino acid scoring patterns recommended by FAO/WHO (1991, 2013) on AAS was estimated. The in vitro–protein digestibility corrected amino acid score (IV–PDCAAS) and in vitro–digestible indispensable amino acid score (IV–DIAAS) were calculated. Overall, pea protein quality varies with different amino acid scoring patterns. Sulfur amino acids (SAA) were the first-limiting amino acid. The IVPD was 80.6 to 88.6%, the mean IV–PDCAAS was 73.0%, and IV–DIAAS was up to 87.6%. Using the PDCAAS interpretation, all IV–PDCAAS samples qualified for a “good source of protein” claim. For DIAAS interpretation, some IV–DIAAS samples did not meet this claim due to the arbitrary cut-off of 75%. Therefore, the criteria for making protein content claims on food proteins should be reevaluated. This study highlighted significant variations in amino acid nutritional requirements across different life stages, impacting the protein quality assessment of field peas and, consequently, protein content claims, with implications for dietary guidelines and food labeling regulations.

SNACK BAR TINGGI SERAT DAN ANTIOKSIDAN BERBAHAN DASAR UBI JALAR UNGU DAN BERAS HITAM SEBAGAI ALTERNATIF SELINGAN PENDERITA DIABETES MELITUS

Type 2 diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to decreased insulin secretion by pancreatic β-cells that requires dietary regulation to control blood glucose levels. Snack bars based on purple sweet potato flour and black rice flour which have high fiber and antioxidant content can be used as an alternative snack food for people with type 2 diabetes mellitus. The purpose of the study was to determine the nutritional content, dietary fiber content, antioxidants content and organoleptic properties of snack bars. This research was experimental with a completely randomized design (CRD) with three comparisons of formulation purple sweet potato flour: black rice flour and 3 repetitions. The results of the nutritional content were analyzed with the Anova test and continued with the Duncan test. While the organoleptic properties were analyzed by Kruskal Wallis test and continued by Man Whitney test. The selection of the selected formulation for snack bar products using the ratio (50%: 50%) from the results of the nutritional content test and organoleptic test. The results of the study show that F3 (70%:30%) snack bar is the selected formulation with nutritional content 100 g, namely energy 425 kcal, protein 13.80 g, fat 21.38 g, carbohydrates 44.23 g, dietary fiber 11.81 g and antioxidants 52.28% with less favorable organoleptic acceptance. The selected snack bar can be claimed as high dietary fiber and antioxidants food.

Dietary Regulation As A Factor Predicting Quality of Life in Diabetic Peripheral Neuropathy Patients

Diabetic peripheral neuropathy is a complication of diabetes mellitus with the number of sufferers continuing to increase from time to time. A decrease in quality of life occurs as this disease progresses, both in physical, mental, and social aspects. Controlling risk factors for declining quality of life needs to be done early, one of the risk factors for declining quality of life is diet. The aim of this research is to analyze dietary regulation as a predictive factor for quality of life in diabetic peripheral neuropathy sufferers. The type of research used is quantitative research with a cross-sectional approach. The respondents in the study were 210 diabetic peripheral neuropathy sufferers who were selected using consecutive sampling techniques. Data collection uses a questionnaire that meets the existing validity and reliability criteria. The data analysis used in this research is SEM PLS analysis. The results show that dietary regulation has a positive influence on quality of life (r=0.236, p=0.0001). Dietary regulation has an effect size on quality of life (f square = 0.095) and also has the ability to predict quality of life well (Q square = 0.232). Dietary regulation is also feasible and suitable in explaining interactions between variables (NFI = 0.540; SRMR = 0.99). The conclusion is dietary regulation can be a good predictive factor for quality of life, so that by improving the diet of diabetic peripheral neuropathy sufferers it will be possible to improve their quality of life.

Molecular characterization and dietary regulation of the forkhead box O3 (foxo3a and foxo3b) in grass carp (Ctenopharyngodon idella)

The forkhead box O3 (foxo3) regulates the target genes expression involved in regulating cell cycle and biological metabolism. In the study, foxo3a and foxo3b of grass carp (Ctenopharyngodon idella) were cloned. The foxo3a cDNA have a complete open reading frame (ORF) spanning 1431 bp, which encodes a polypeptide of 476 amino acids. The foxo3b cDNA contains a complete ORF encompassing 1959 bp, encoding a protein consisting of 652 amino acid residues. The analysis of genetic codon preference and phylogenetic relationships revealed that the foxo3a and foxo3b genes in grass carp are closely related to the counterparts of Danio rerio and Megalobrama amblycephala. Tissue expression analysis showed that foxo3a expression reached the maximum in the brain while foxo3b expression in the muscle being the highest. Circadian expression pattern showed that, foxo3a expression presented a periodic upward trend from 3:00–9:00, 12:00–18:00 and 21:00–24:00, and the maximum level of foxo3b was detected at 9:00. Moreover, dietary regulation of foxo3a and foxo3b expression were performed in our research. In the feeding trial with different protein sources, the groups of fishmeal, rapeseed meal and soybean meal are in contrast to each other. Foxo3a expression was significantly higher in fish fed with rapeseed meal compared to those fed with soybean meal and fishmeal at 14th and 21st days of the experiment. Foxo3b expression was highest in the fishmeal group, followed by rapeseed meal, while it was lowest in soybean meal at 14th and 28th days. Analysis of the effect of dietary alanine-glutamine dipeptide on foxo3 expression in grass carp revealed that the expression of foxo3a gradually increased with increasing dietary Ala-Gln dipeptide concentration and reached its highest level at a concentration of 1.5%. Conversely, foxo3b expression significantly decreased when the dipeptide concentration reached 2%. The findings of this study may provide new insights into the molecular properties, spatiotemporal dynamics, and nutritional regulation of foxo3 in fish.

O.4.5-6 Psychosocial approach of dysfunctional eating attitude and behaviors in endurance sport: comparison of competitive and practice periods

Abstract Purpose Most of the determinants of the dysfunctional eating attitude and behaviors (DEAB) mentioned so far have been reported in aesthetic sports or weight categories and may therefore not be representative of all endurance athletes. Moreover, to our knowledge, very few studies have focused on the evolutionary nature of these variables during a sports season. The objective of this research was to identify the triggers of the implementation of inappropriate behaviors for the health and performance of endurance athletes. Methods The sample consisted of 14 French female athletes aged 18 or over who practiced an endurance sport more than 12 hours a week for more than 5 years. All athletes were at the national or international level. For one year, participants answered online questionnaires through an Athlete Management System. They were followed daily on the sports period, weekly on self-regulation of eating attitude in sport, and self-perceptions and quarterly on psychosocial parameters related to DEAB. Results The ANOVA performed showed that anxiety levels were higher and resilience levels lower in athletes with DEAB compared to other athletes, and anxiety levels tended to increase during competitive periods only in athletes with DEAB. On the other hand, the level of resilience of athletes does not vary significantly depending on the period of competition or training. The analyses performed revealed also indicate dietary regulation behaviors and a higher level of internalization of slimming standards when athletes were in competition compared to training phases. Conclusions Although DEAB are an increasing concern in the sport context, the specificity of DEAB in athletes can represent a challenge for stakeholders. It seems necessary that stakeholders from all fields to have a precise knowledge of the personal characteristics related to sports practice that could favor the DEAB development, to be able to carry out an appropriate evaluation allowing subsequently to propose avenues of intervention adapted to the realities of them. Support/Funding Source This research project was supported by the French athletics federation and financially supported by “Sport pour elles, FDJ”.

The Implementation of Diet In Pre-Diabetic Versus Diabetic Patients In Long Term Texas Facilities

Diabetes Mellitus and Pre-Diabetes Mellitus are two of the fastest growing diseases in the world (Toft 1). While extensive research has been done regarding dietary regulations in Diabetics, there is a lack of pre-existing research addressing diet regulations in Pre-diabetics. Considering diet plays a crucial role in the recovery process of these patients, the scarcity of information regarding diet regulation in Pre-Diabetics is quite alarming. Thus, this study focuses on examining the implementation of diet in Diabetic versus Pre-diabetic patients in long term Texas Facilities. To assess the adherence to the CDC’s Recommended Dietary Allowances, 12 long term Texas facilities participated in one or more of the following 3 methods: a quantitative questionnaire, qualitative interviews, and both a quantitative and qualitative dietary menu analysis. The results concluded that the extent to which the CDC’S recommended dietary allowances are implemented in the diet of Pre-diabetic patients in Texas facilities is much less efficient than in diabetics due to leniency of dietary regulation, granting of dietary requests, longer monitoring intervals, and lack of priority towards educating the patient on dietary restrictions in Pre-diabetics.

Effects of Dietary Supplementation with Mulberry Leaf Powder on the Growth Performance, Lipid Metabolism Parameters, Immunity Indicators, and Gut Microbiota of Dogs.

Overfeeding and a lack of exercise are increasingly causing obesity in dogs, which has become a big problem threatening the health of dogs. Therefore, it is necessary to investigate how dietary regulations can help to improve dogs' body conditions and minimize obesity. This study was carried out to investigate the effects of dietary mulberry leaf powder (MLP) supplementation on the growth performance, lipid metabolism parameters, and gut microbiota of Chinese indigenous dogs. Fifteen Chinese indigenous dogs (6.34 ± 0.56 kg) were randomly assigned to three treatment groups and received either the control diet (CON), high-fat diet (HF), or high-fat diet containing 6% Mulberry leaf powder (MLP) for four weeks. The CON group received a basal diet, the HF group received a basal diet supplemented with 10% lard, and the MLP group received a basal diet supplemented with 10% lard and 6% MLP. The trial lasted for four weeks. The growth performance, lipid metabolism parameters, immune globulins, cytokines, and fecal microbiota were measured. Results showed that there was no significant difference in growth performance. The MLP group appeared to have decreased (p < 0.05) the serum level of low-density lipoprotein cholesterol (LDL-C) and apoliprotein-A1(APO-A1) in serum. The MLP group appeared to have higher (p < 0.05) serum immune globulin A (IgA) levels. UPGMA results showed that the MLP group was closer to the CON group than to the HF group. LEfSe analysis showed that dietary supplementation with MLP contributed to an alteration in the genus Alloprevotella, Sarcina, and species belonging to the Bacteroides and Lactobacillus genus. Overall, the dietary supplementation of 6% MLP can improve lipid metabolism conditions and immunity in high-fat-diet-fed dogs, and can alter the gut microbial composition of dogs.

Identifying and ranking causal microbial biomarkers for colorectal cancer at different cancer subsites and stages: a Mendelian randomization study.

The gut microbiome is directly involved in colorectal carcinogenesis, but much of the epidemiological evidence for the effect of the gut microbiome on colorectal cancer (CRC) risk comes from observational studies, and it is unclear whether identified microbial alterations are the cause or consequence of CRC development. Univariate Mendelian randomization (MR) analysis and multivariate MR analysis based on Bayesian model averaging were performed to comprehensively explore the microbial risk factors associated with CRC. The Network Module Structure Shift method was used to identify microbial biomarkers associated with CRC. Mediation analysis was used to explore the dietary habits-microbiota-CRC pathway. The results of the four methods showed that 9 bacteria had a robust causal relationship with the development of CRC. Among them, Streptococcus thermophilus reduced the risk of CRC; Eubacterium ventriosum and Streptococcus were beneficial bacteria of malignant tumors of colon (CC); Erysipelotrichaceae was a protective factor for malignant tumors of rectal (CR); Bacteroides ovatus was a risk factor for benign tumors. Finally, the mediation analysis revealed 10 pathways by which dietary regulation bacteria affected the risk of CRC, including alcohol consumption increased the risk of CC by reducing the abundance of Eubacterium ventriosum (mediated proportion: 43.044%), and the mediated proportion of other pathways was 7.026%-34.22%. These findings will contribute to the understanding of the different carcinogenic mechanisms of intestinal flora in the colon and rectum and the risk of tumor transformation, thereby aiding CRC prevention, early screening, and the development of future strategies to reduce CRC risk.

Autism Spectrum Disorder is Related to Increasing Intestinal Prevotella That Can Be Regulated by Vitamin A

Background: Increasing studies suggest that the microbiome-gut-brain axis plays a fundamental role in developing autism spectrum disorder (ASD). Objectives: We aimed to explore biomarkers from gut bacteria in ASD and the dietary vitamin A (VitA) relationship with intestinal bacteria of autistic children and provide a theoretical basis for dietary regulation of ASD. Methods: Ten autistic children aged 2 to 6 from special training facilities were enrolled from 2017 to 2018. At the same time, 10 healthy children aged 2 to 6 from a kindergarten were collected as a control. All participants were from Chongqing, China. The 16sRNA amplicon sequencing was used to analyze children's intestinal bacteria. The serum retinol level was detected by high-performance liquid chromatography (HPLC), and children's dietary intake was analyzed using three-day 24-hour dietary recalls. Results: There were significant differences in alpha diversity between the groups. Also, a higher relative abundance of Prevotellaceae, Prevotella 9, and Roseburia was observed among ASD children. We also found decreases in 9 bacteria (Enterobacteriales, Gammaproteobacteria, Enterobacteriaceae, Clostridiaceae 1, Clostridium sensu stricto 1, Escherichia-Shigella, Bacteroides fragilis, Escherichia coli, and Clostridium neonatale). Dietary VitA intake and serum retinol concentration were lower in the ASD group than in the control group. Meanwhile, serum VitA had a significantly negative correlation with the abundance of intestinal Prevotella 9. Conclusions: Our study helps identify some bacterial biomarkers for ASD, as in previous reports. Meanwhile, the study suggests that dietary VitA may be involved in the clinical symptoms of ASD by regulating the intestinal bacteria Prevotella. It may provide a new way to treat ASD in the future. Further studies are needed to identify the results by expanding the sample size and developing animal experiments.

Auricularia auricular Adsorbs Aflatoxin B1 and Ameliorates Aflatoxin B1-Induced Liver Damage in Sprague Dawley Rats.

Aflatoxin B1 (AFB1), as a class I carcinogen, poses a substantial health risk to individuals. Contamination of food sources, particularly grains and nuts, with Aspergillus flavus (A. flavus) contributes to the prevalence of AFB1. The impact of global warming has spurred research into the development of AFB1 prevention technologies. While edible fungi have shown potential in detoxifying AFB1, there is a scarcity of literature on the application of Auricularia auricular (A. auricular) in this context. This study aimed to investigate the ability and underlying mechanism of A. auricular mycelia to adsorb aflatoxin B1, as well as evaluate its protective effects on the AFB1-induced liver damage in SD rats. Additionally, the effects of temperature, time, pH, and reaction ratio on the adsorption rate were examined. Combining thermodynamic and kinetic data, the adsorption process was characterized as a complex mechanism primarily driven by chemical adsorption. In SD rats, the A. auricular mycelia exhibited alleviation of AFB1-induced liver damage. The protective effects on the liver attributed to A. auricular mycelia may involve a reduction in AFB1 adsorption in the intestine, mitigation of oxidative stress, and augmentation of second-phase detoxification enzyme activity. The adsorption method for AFB1 not only ensures safety and non-toxicity, but also represents a dietary regulation strategy for achieving effective defense against AFB1.

Edukasi Self-Management terhadap Pengaturan Pola Makan dan Konsumsi Obat pada Pasien DM Tipe 2

This study aims to determine the effectiveness of self-management education on drug consumption and diet management in patients with Type 2 DM at the East Aceh Health Center. The research method used is quantitative research with a quasi-experimental design. The results showed that the average pretest and posttest results were 27.24 and 29.51 posttest, 8.18 pretest, and 11.10 posttest results. The statistical test results showed a significant difference between the pretest and posttest of dietary adjustments and drug consumption. There is an increase in dietary regulation and drug consumption after self-management education. In conclusion, the provision of self-management education effectively regulates diet and drug consumption in patients with Type 2 DM in the working area of the Idi Rayeuk Health Center.&#x0D; &#x0D; Keywords: Type 2 Diabetes Mellitus, Self-Management Education, Self-care

Philosophically, is obesity really a disease?

The question of whether obesity should be regarded as a disease remains controversial. One source of controversy can be addressed by distinguishing between two ways in which the word "obesity" is used. In medicine, the word "obesity" now typically refers to some or all of a set of interrelated dysfunctions of metabolism, adipose tissue, and dietary intake regulation. In other contexts, such as government-funded public education programs, the word "obesity" refers to a body mass index (BMI) category taken to indicate excess body fat. The result is that when medical experts say, "Obesity is a disease," the majority of outside medicine inevitably takes this to mean "being fat is a disease." In order to address this ambiguity, we apply key philosophical accounts of disease to the two different senses of "obesity." We draw two major conclusions: First, although obesity as understood in clinical medicine meets the criteria to be considered a disease, obesity as defined by BMI does not. Second, adequately addressing this disease requires us to distinguish it clearly and unambiguously from high BMI. Making this distinction would help both the public and policymakers to better understand the disease of obesity, facilitating advances in both prevention and treatment.