Dibutyric Acid Research Articles

Crystal Structure of 1,4-Piperazine-γ,γ′-Dibutyric Acid

1,4-Piperazine-γ,γ′-dibutyric acid, was prepared during investigations in polymer chemistry, and gave an infra-red spectrum which was inconsistent with both the normal COOH—COOH dimerization and zwitterion form of amino-acids. It appeared, therefore, that the hydrogen bonding might be of an unusual type, and, in view of this possibility, the crystal structure has been determined by X-ray methods.

The Reaction between Diphenylalkanes and Maleic Anhydride by the Friedel and Crafts Method

Abstract (1) By the reaction of diphenylmethane and diphenylethane with maleic anhydride in the presence of aluminium chloride, diphenyl-methane-4, 4′-di-γ-oxocrotonic acid and biben-zyl-4,4′-di-γ-oxocrotonic acid were produced, respectively. And cis and trans isomers of dimethyl esters of these acids were prepared. (2) By the reduction of the above two acids by zinc and acetic acid, diphenyl-methane-4, 4′-di-γ-oxobutyric acid and biben-zyl-4, 4′-di-γ-oxobutyric acid were prepared. (3) These saturated keto acids were reduced by amalgamated zinc in the mixture of ethanol and hydrochloric acid to diphenyl-methane-4,4′-dibutyric acid and diphenyl-ethane-4, 4′-dibutyric acid.