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SUCCESSFUL TREATMENT OF RAYNAUD'S SYNDROME WITH ILOPROST, A CHEMICALLY STABLE PROSTACYCLIN ANALOGUE

Twelve female patients with severe secondary Raynaud's phenomenon were treated in a randomized order with both placebo and Iloprost infusions. Infusions were for 5 hours on 3 consecutive days and Iloprost was administered at variable dosage from 1.0 to 3.0 ng/kg/min. A 6-week follow-up period was used between the two sets of infusions. A significant number of patients reported Iloprost had improved Raynaud's symptomatology compared with placebo and this effect lasted for up to 6 weeks. The number of attacks of Raynaud's as recorded by patients in diary books was similarly reduced after Iloprost. Digital and nail-bed blood flows measured by laser-Doppler methods were increased for up to 6 weeks after Iloprost, but not after placebo infusions. Iloprost may be a useful therapeutic agent in the treatment of severe secondary Raynaud's syndrome.

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Rheumatology
Jan 1, 1988
D A Yardumian + 6

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The Use of Multiple Diaries in a Household Expenditure Survey in Hong Kong

Abstract This article discusses two aspects of using daily expenditure records, commonly referred to as diaries, in a household expenditure survey, based on the experience of the 1979–1980 Hong Kong Household Expenditure Survey. In particular, the article investigates the determinants of the decision by individual household members to fill out diaries, conditional upon the household having agreed to participate in the survey. In addition, estimates are presented of the additional reporting that results from household members keeping individual diaries, as opposed to one member keeping one household diary book.

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