Introduction. Current advances in war-waging strategies have imposed new demands on public medical care and civil defense forces amid social emergency settings. Elimination of medical and sanitary consequences of emergencies compels to explore new horizons in order to develop advanced approaches and strategies of medical care provided to victims at all stages of medical evacuation among affected population, emergency rescue personnel of various departmental affiliations, including military personnel of military rescue formations.The objective is to share the experience of cross-departmental medical forces providing medical care to victims amid disrupted and non-functional healthcare services due to biological and social emergency of regional scale.Results and analysis. The paper describes experience of medical aid efforts in the newly incorporated regions of Russia, suggesting a cross-institutional strategy of dedicated medical care provision to the population and military rescue personnel amid social emergency settings.Conclusion. Deployment of cross-institutional medical forces allows to reinforce the capacities of regular medical organizations in emergency areas, whereas advanced diagnostic, treatment and medical evacuation technologies allow to stabilize the condition of victims to carry out evacuation “as intended” within most optimal timeframes.