Pneumoconiosis, a collective term for lung diseases resulting from the inhalation of specific dusts, presents significant global public health and economic challenges1. This is particularly prevalent in traditional sectors like mining and metal industries, and emerging industries such as nuclear fuel processing. Notably, nations like China and India have over 20 million workers at risk. While awareness around pneumoconiosis has been prevalent for decades, its status as a leading occupational disease, especially in regions like China, indicates a deficiency in current mitigation policies. This essay delves into the present diagnostic and treatment measures for pneumoconiosis, its prevention strategies, worldwide trends, and the existing policies from governmental and private entities, highlighting areas for enhancement. The global resurgence of pneumoconiosis underscores the pressing need for a thorough reassessment of workplace regulations and the creation of novel standards tailored to emergent industries. Comprehensive research aimed at identifying air pollutants and associated risks in new industry workspaces is imperative. Collaborative endeavors from governmental and private sectors should focus on enhanced protective gear, workplace safety education, and comprehensive medical insurance. Innovative strategies, like forecasting potential workplace pollutants, can bridge the gap between policy enforcement and safety measures, aiming to reduce the influence of this incapacitating ailment.