Diagnosis Of Paraneoplastic Encephalitis Research Articles

Steroid-responsive dual neuronal antibody-positive paraneoplastic encephalitis

Here, we report the case of an elderly African male with multifocal neuraxial involvement in the form of progressive parkinsonism and ataxia over a year. On evaluation, dual neuronal antibody positivity was detected. A diagnosis of paraneoplastic encephalitis was made without any detection of primary neoplasm. He was successfully managed with pulse steroid therapy followed by oral steroid and steroid-sparing oral immunosuppressive drug without any need for intravenous immunoglobulin or plasma exchange.

Testicular teratoma and anti-N-methyl-D-aspartate receptor-associated encephalitis

We report a patient with a testicular teratoma and seminoma, who developed treatment-responsive encephalitis associated with antibodies to NMDA receptor, but not antibodies to Ma2 protein. A 30-year-old male was...