Diagnosis Of Fracture Research Articles

Clinical experience of a patient with hemopericardium

Introduction: pericardial effusion is a frequent entity in daily practice, which can occur due to a wide range of pathologies, it is the result of an increase in the blood content of the pericardial sac.Case presentation: female patient, white skin, 93 years old, presented with a fall on her own feet, was taken to the Orthopedics and Traumatology Department where a diagnosis of intertrochanteric right hip fracture was made and admission to the observation room was indicated for subsequent surgical treatment. The patient began to become tachycardic 110/min, hypotensive 80/50 mmHg, she began to resuscitate with volume responding to fluid minirection (4ml/Kg). Hematocrit was repeated and found to be 0.25, her state of shock was attributed as hypovolemic hemorrhagic. Signs of tissue hypoperfusion persisted, despite the prescribed measures and increased vasopressor requirements. It was decided to perform an echocardiogram where there were evident signs of pericardial effusion. Pericardial window and hemostasis of the bleeding site were performed, achieving the survival of this case. Conclusions: hemopericardium is an entity with a reserved prognosis, which may occur due to a wide range of traumatic and non-traumatic pathologies; imaging methods are a key diagnostic tool, transthoracic echocardiography is the first line method for its evaluation. Therapeutic percutaneous approach, surgical exploration, as well as pericardiocentesis are therapeutic methods

VerFormer: Vertebrae-Aware Transformer for Automatic Spine Segmentation from CT Images.

The accurate and efficient segmentation of the spine is important in the diagnosis and treatment of spine malfunctions and fractures. However, it is still challenging because of large inter-vertebra variations in shape and cross-image localization of the spine. In previous methods, convolutional neural networks (CNNs) have been widely applied as a vision backbone to tackle this task. However, these methods are challenged in utilizing the global contextual information across the whole image for accurate spine segmentation because of the inherent locality of the convolution operation. Compared with CNNs, the Vision Transformer (ViT) has been proposed as another vision backbone with a high capacity to capture global contextual information. However, when the ViT is employed for spine segmentation, it treats all input tokens equally, including vertebrae-related tokens and non-vertebrae-related tokens. Additionally, it lacks the capability to locate regions of interest, thus lowering the accuracy of spine segmentation. To address this limitation, we propose a novel Vertebrae-aware Vision Transformer (VerFormer) for automatic spine segmentation from CT images. Our VerFormer is designed by incorporating a novel Vertebrae-aware Global (VG) block into the ViT backbone. In the VG block, the vertebrae-related global contextual information is extracted by a Vertebrae-aware Global Query (VGQ) module. Then, this information is incorporated into query tokens to highlight vertebrae-related tokens in the multi-head self-attention module. Thus, this VG block can leverage global contextual information to effectively and efficiently locate spines across the whole input, thus improving the segmentation accuracy of VerFormer. Driven by this design, the VerFormer demonstrates a solid capacity to capture more discriminative dependencies and vertebrae-related context in automatic spine segmentation. The experimental results on two spine CT segmentation tasks demonstrate the effectiveness of our VG block and the superiority of our VerFormer in spine segmentation. Compared with other popular CNN- or ViT-based segmentation models, our VerFormer shows superior segmentation accuracy and generalization.

Study on automatic and rapid diagnosis of distal radius fracture by X-ray

This article aims to combine deep learning with image analysis technology and propose an effective classification method for distal radius fracture types. Firstly, an extended U-Net three-layer cascaded segmentation network was used to accurately segment the most important joint surface and non joint surface areas for identifying fractures. Then, the images of the joint surface area and non joint surface area separately were classified and trained to distinguish fractures. Finally, based on the classification results of the two images, the normal or ABC fracture classification results could be comprehensively determined. The accuracy rates of normal, A-type, B-type, and C-type fracture on the test set were 0.99, 0.92, 0.91, and 0.82, respectively. For orthopedic medical experts, the average recognition accuracy rates were 0.98, 0.90, 0.87, and 0.81, respectively. The proposed automatic recognition method is generally better than experts, and can be used for preliminary auxiliary diagnosis of distal radius fractures in scenarios without expert participation.

SonoBox: development of a robotic ultrasound tomograph for the ultrasound diagnosis of paediatric forearm fractures.

Paediatric forearm fractures are a prevalent reason for medical consultation, often requiring diagnostic X-rays that present a risk due to ionising radiation, especially concerning given the sensitivity of children's tissues. This paper explores the efficacy of ultrasound imaging, particularly through the development of the SonoBox system, as a safer, non-ionising alternative. With emerging evidence supporting ultrasound as a viable method for fracture assessment, innovations like SonoBox will become increasingly important. In our project, we want to advance ultrasound-based, contact-free, and automated cross-sectional imaging for diagnosing paediatric forearm fractures. To this end, we are building a technical platform that navigates a commercially available ultrasound probe around the extremity within a water-filled tank, utilising intelligent robot control and image processing methods to generate a comprehensive ultrasound tomogram. Safety and hygiene considerations, gender and diversity relevance, and the potential reduction of radiation exposure and examination pain are pivotal aspects of this endeavour. Preliminary experiments have demonstrated the feasibility of rapidly generating ultrasound tomographies in a water bath, overcoming challenges such as water turbulence during probe movement. The SonoBox prototype has shown promising results in transmitting position data for ultrasound imaging, indicating potential for autonomous, accurate, and potentially painless fracture diagnosis. The project outlines further goals, including the construction of prototypes, validation through patient studies, and development of a hygiene concept for clinical application. The SonoBox project represents a significant step forward in paediatric fracture diagnostics, offering a safer, more comfortable alternative to traditional X-ray imaging. By automating the imaging process and removing the need for direct contact, SonoBox has the potential to improve clinical efficiency, reduce patient discomfort, and broaden the scope of ultrasound applications. Further research and development will focus on validating its effectiveness in clinical settings and exploring its utility in other medical and veterinary applications.

Mortality, perioperative complications and surgical timelines in hip fracture patients: Comparison of the Spanish with the non-Spanish Cohort of the HIP ATTACK-1 trial

BackgroundHip fractures carry a substantial risk of complications and death. This study aimed to report the 90-day incidence of mortality, major perioperative complications and in-hospital timelines after a hip fracture in the Spanish HIP ATTACK-1 trial cohort, comparing with the non-Spanish cohort. MethodsProspective cohort study of Spanish patients nested in the HIP ATTACK-1 trial. The HIP ATTACK-1 was an international, randomized, controlled trial (17 countries, 69 hospitals, 7 in Spain, highest recruiting country). Patients were randomized to either accelerated surgery (goal of surgery within 6 h of diagnosis) or standard care. Participants were ≥45 years of age who presented with a low-energy hip fracture requiring surgery. ResultsAmong 534 patients in the Spanish cohort, 69 (12.9 %) patients died at 90 days follow-up, compared to 225 (9.2 %) in the non-Spanish cohort (p = 0.009), mostly due to higher nonvascular related mortality. A composite of major postoperative complication occurred in 126 patients (23.6 %). The most common perioperative complications were myocardial injury (189 patients, 35.4 %), infection with no sepsis (86 patients, 16.1 %) and perioperative delirium (84 patients, 15.7 %); all these complication rates in Spain were significantly higher than the non-Spanish patients (29.2 % p = 0.005; 11.9 % p = 0.008 and 9.2 % p < 0.0001, respectively). Spanish cohort patients were older and had more comorbidities than the non-Spanish cohort, evidencing their greater frailty at baseline. Among Spanish patients, the median time from hip fracture diagnosis to surgery was 30.0 h (IQR 21.1–53.9) in the standard-care group, with 68.8 % of patients receiving surgery within 48 h of diagnosis. This median time was lower in the non-Spanish cohort (22.8 h, IQR 9.5–37.0), where 82.1 % of patients were operated within 48 h. ConclusionsIn the HIP ATTACK-1 trial, 1 in 8 patients died 90 days after a hip fracture in Spain. The most common complication after a hip fracture was myocardial injury, followed by infection and delirium. Spanish patients had worse outcomes than non-Spanish patients. Research needs to focus on new interventions such as accelerated surgery and perioperative troponin measurement with the appropriate investment of resources, to prevent and identify early these complications with a goal of improving mortality for this high-risk population. Level of evidenceII

RECTANGULAR TAPER STEM DESIGNS ARE ASSOCIATED WITH A HIGHER RISK FOR PERIPROSTHETIC FEMORAL FRACTURES AFTER CEMENTLESS TOTAL HIP ARTHROPLASTY

Periprosthetic femoral fractures (PFFs) remain a major concern following cementless total hip arthroplasty (THA). This study aimed to evaluate the association between different types of cementless tapered stems and the risk of postoperative PFF.A retrospective review of primary THAs performed at a single center from January 2011 to December 2018 included 3,315 hips (2,326 patients). Cementless stems were classified according to their design geometry using the system proposed by Radaelli et al. The incidence of PFF was compared between flat taper porous-coated stems (type A), rectangular taper grit-blasted stems (type B1), and quadrangular taper hydroxyapatite-coated stems (type B2). Multivariate regression analyses were performed to identify independent factors related to PFF. The mean follow-up duration was 61 months (range, 12‒139 months).Overall, 45 (1.4%) postoperative PFFs occurred. The incidence of PFF was significantly higher in type B1 stems than in type A and type B2 stems (1.8 vs. 0.7 vs. 0.7%; P=0.022). Additionally, more surgical treatments (1.7 vs. 0.5 vs. 0.7%; P=0.013) and femoral revisions (1.2 vs. 0.2 vs. 0%; P=0.004) were required for PFF in type B1 stems. After controlling for confounding variables, older age (P&lt;0.001), diagnosis of hip fracture (P&lt;0.001), and use of type B1 stems (P=0.001) were significant factors associated with PFF.Type B1 rectangular taper stems were found to have higher risks for postoperative PFF and PFF requiring surgical management than type A and type B2 stems in THA. Femoral stem geometry should be considered when planning for cementless THA in elderly patients with compromised bone quality.

Impact of CBCT acquisition protocols and artifact reduction filters on diagnosing vertical root fractures.

To evaluate the impact of acquisition protocols and artifact reduction filters in cone beam computed tomography on diagnosing vertical root fractures in endodontically treated teeth with and without intraradicular posts. We analyzed 480 tomographic images acquired from two J. Morita scanners (0.125- and 0.08-mm voxel sizes protocols), with application of a blooming artifact reduction filter. Three evaluators assessed these images for root fractures using a 5-point Likert scale. Diagnostic accuracy between filters and protocols was determined using generalized linear models with binomial distribution for the outcome, considering protocol, filter, and dental status. Sensitivity, specificity, positive predictive value, and negative predictive value were also estimated for the filters and protocols. The 0.08-mm voxel size protocol demonstrated a significantly higher percentage of accurate diagnosis compared to the 0.125-mm protocol (p = .001). No statistically significant differences (p ≥ .087) were observed for filter application, interaction between protocol and filter, or dental status. Accuracy, sensitivity, and specificity values were respectively: .93, .87, 1.00 (protocol 1); .99, .99, .99 (protocol 2); .98, .96, .99 (no filter); .95, .90, 1.00 (with filter). The new findings found for the two J Morita scanners used in our study were that images acquired using the voxel size of 0.08 mm showed an improvement in the diagnosis of root fractures and the filters in these devices have no relevance significant for the diagnosis.

[Translated article] Evaluation, differential diagnosis and treatment of vertebral osteoporosis: How to avoid the occurrence of new fractures

Osteoporosis is a highly prevalent and multifactorial disease whose main manifestation is the appearance of fragility or low-impact fractures. The most frequent locations of osteoporotic fractures occur at the vertebrae, femoral, distal end of the radius and humerus. Osteoporotic vertebral fracture deserves special mention among them due to its prevalence, importance as it often goes unnoticed and medium-long term consequences are: pain, deformity, disability and deterioration in quality of life. In this review we will focus on the classification and initial evaluation of the patient with osteoporosis, estimation of risk factors, laboratory and imaging studies for an adequate assessment using simple radiography, dual densitometry and magnetic resonance imaging. We will also address the main aspects of the differential diagnosis, treatment and prevention of vertebral fragility fracture, briefly reviewing the main therapeutic agents currently used for its prevention and treatment.

Implementation status of comprehensive geriatric assessment among older inpatients: A nationwide retrospective study.

The importance of comprehensive geriatric assessment (CGA) is increasing in aging societies worldwide. However, there are few comprehensive studies on CGA, resulting in a limited understanding of its implementation rate, temporal changes and factors associated with its implementation. We aimed to investigate the implementation status of CGA and its regional variance in Japan. Using the Diagnosis Procedure Combination database, we investigated CGA trends, and identified the patient, hospital and regional factors associated with its implementation. We identified patients aged ≥65 years who were admitted for the first time between 2016 and 2020 with a diagnosis of stroke, heart failure, pneumonia, bone fracture or colorectal cancer. We examined the CGA implementation rate according to patient and hospital characteristics. We also investigated temporal changes and tendencies to carry out CGA in different prefectures. A total of 1 974 817 patients were analyzed, of whom 570 696 (28.9%) underwent CGA. The implementation trend increased steadily from 25.3% in fiscal year 2016 to 33.4% in fiscal year 2019. The implementation rate also increased with patient age (30.3% in patients aged ≥95 years). Regional variations in its implementation status were observed, with a higher tendency to be implemented in areas near major metropolitan regions. A trend toward carrying out CGA for colorectal cancer, but not for other diseases, has been observed in eastern Japan. Although CGA is increasingly carried out, considerable regional differences remain in its implementation status. Initiatives to reduce variations are necessary. Geriatr Gerontol Int 2024; ••: ••-••.

The combined talus and sustentaculum fracture: A case series

BackgroundThe sustentaculum tali is a biomechanically important stabilizer of the hindfoot and contributes to articular congruency of the subtalar joint. Sustentaculum injury associated with a talus fracture has been described infrequently and treatment of this combined injury varies. The purpose of this study was to describe and evaluate the outcomes of the combined talus and sustentaculum fracture. MethodsRetrospective chart and radiographic review was performed on all talus fractures (n = 436) requiring operative fixation over a 21-year period at a single Level-1 trauma center. All talus fractures with sustentaculum fractures were included. Statistical analysis was performed using Chi-squared and Fishers exact tests where appropriate. ResultsSustentaculum fractures occurred in 6.2 % (n = 27) of patients with talus fractures. Average follow-up was 14 months; 18.5 % were open fractures, 88.8 % were from high-energy mechanisms, and 44.4 % were polytraumas. Diagnosis of the sustentaculum fracture was missed on presenting radiographs in 69.2 % (n = 18). The most common associated talus fracture was a talar neck fracture (40.7 %) and the majority (73.7 %) were Hawkins II. Overall, 40.7 % (n = 11) of the sustentaculum fractures were treated with independent fixation and 7.4 % (n = 2) were treated with acute subtalar arthrodesis. Subtalar post-traumatic osteoarthritis (PTOA) at final follow-up was seen in 23.1 % of combined injuries. Independent sustentaculum fixation did not influence the rate of PTOA or re-operation (p = 0.92, p = 0.91, respectively). ConclusionTalar fractures have an associated sustentaculum fracture in approximately 6 % of cases, especially with Hawkins II fracture-dislocations. Over two-thirds of the associated sustentaculum fractures were missed on presenting radiographs, reiterating the need for heightened awareness and consideration of advanced imaging for all talus fractures. The rate of PTOA following these combined injuries at mean follow-up of 24 months does not exceed established rates after isolated talus fractures. Further research is required to determine the optimal management of the sustentaculum in these combined injuries. Level of evidenceIV

The establishment of a novel upper cervical complex fracture classification system

BACKGROUND CONTEXTUpper cervical complex fractures are associated with high rates of neurological damage and mortality. The Dickman's classification is widely used in the diagnosis of upper cervical complex fractures. However, it falls short of covering the full spectrum of complex fractures. This limitation hinders effective diagnosis and treatment of these injuries. PURPOSETo address the diagnostic gap in upper cervical complex fractures, the study introduces a novel classification system for these injuries, assessing its reliability and usability. STUDY DESIGNProposal of a new classification system for upper cervical complex fractures. PATIENT SAMPLEThe study comprised the clinical data of 242 patients with upper cervical complex fractures, including 32 patients treated at our hospital, along with an additional 210 cases from the literature. OUTCOME MEASURESThe inter-observer and intra-observer reliability (kappa coefficient, κ) of this classification system were investigated by 3 spine surgeons. The 3 researchers independently re-evaluated the upper cervical complex fracture classification system 3 months later. METHODSThe proposed classification categorizes upper cervical complex fractures into 3 main types: Type I combines odontoid and Hangman's fractures into 2 subtypes; Type II merges C1 with odontoid/Hangman's fractures into 3 subtypes; and Type III encompasses a combination of C1, odontoid, and Hangman's fractures, divided into 2 subtypes. Meanwhile, a questionnaire was administered in 15 assessors to evaluate the system's ease of use and clinical applicability. RESULTSA total of 45 cases (18.6%) unclassifiable by Dickman's classification were successfully categorized using our system. The mean κ value of inter-observer reliability was 0.783, indicating substantial reliability. The mean κ value of intra-observer reliability was 0.862, indicating almost perfect reliability. Meanwhile, thirteen assessors (87.7%) stated that the classification system is easy to remember, easy to apply, and they expressed intentions to apply it in clinical practice in the future. CONCLUSIONSThis system not only offers high confidence and reproducibility but also serves as a precise guide for clinicians in formulating treatment plans. Future prospective applications are warranted to further evaluate this classification system.

Real-time monitoring of rock fracture by true triaxial test using fiber-optic strain monitoring in adjacent wells

The real-time monitoring of fracture propagation during hydraulic fracturing is crucial for obtaining a deeper understanding of fracture morphology and optimizing hydraulic fracture designs. Accurate measurements of key fracture parameters, such as the fracture height and width, are particularly important to ensure efficient oilfield development and precise fracture diagnosis. This study utilized the optical frequency domain reflectometer (OFDR) technique in physical simulation experiments to monitor fractures during indoor true triaxial hydraulic fracturing experiments. The results indicate that the distributed fiber optic strain monitoring technology can efficiently capture the initiation and expansion of fractures. In horizontal well monitoring, the fiber strain waterfall plot can be used to interpret the fracture width, initiation location, and expansion speed. The fiber response can be divided into three stages: strain contraction convergence, strain band formation, and postshutdown strain rate reversal. When the fracture does not contact the fiber, a dual peak strain phenomenon occurs in the fiber and gradually converges as the fracture approaches. During vertical well monitoring in adjacent wells, within the effective monitoring range of the fiber, the axial strain produced by the fiber can represent the fracture height with an accuracy of 95.6% relative to the actual fracture height. This study provides a new perspective on real-time fracture monitoring. The response patterns of fiber-induced strain due to fractures can help us better understand and assess the dynamic fracture behavior, offering significant value for the optimization of oilfield development and fracture diagnostic techniques.

Evaluation of Fluid Distribution and Perforation Erosion in Multistage Fracture Treatment

Summary Fracture monitoring and diagnosis by fiber-optic sensing technology provides invaluable information about stimulation efficiency. This technology becomes more critical for multistage fracturing over long horizontal wells. The combined analysis of distributed temperature sensing (DTS) and distributed acoustic sensing (DAS) measurements has been used to map the fluid distribution during hydraulic fracturing, and fracture volume at the cluster level and at the stage level can be estimated from the analysis. In this paper, based on the interpretation of models for DTS and DAS, we extend the application to fluid containment and stage isolation evaluation. In plug and perforation hydraulic fracturing, when a stage is finished pumping, the stage is isolated by a plug, and the next stage is perforated and then fractured. If the plug is not functioning correctly, fracture fluid enters the previous stage, causing an uneven fluid distribution, and possibly more severe perforation erosion. Both DAS and DTS monitoring can record this phenomenon when it happens. Interpretation models are built to quantify the fluid distribution with the effect of plug leakage included. From DTS measurements, cooling below the stage being completed is counted as the fluid from the current stage. Given this information, the reservoir thermal model can estimate the volume of leakage. From the DAS measurement, we interpret the volume distribution based on frequency band energy to compare with the DTS interpretation. Perforation erosion measurements from a downhole camera are used to confirm the estimation. With this approach, we assess the fluid distribution, plug performance, and the importance of stage isolation on perforation erosion during a multistage fracture treatment. The information can then be used to analyze and optimize completion and fracture treatment design. Field examples are presented in the paper to support the discussion, findings, and conclusions. Based on the results of the fluid distribution estimated, we observed that higher injection rate and larger fluid volumes may create more uniformly distributed fluid between clusters in a stage. When considering communication between stages, the DTS and downhole camera show that there is a correlation between fluid distribution and perforation eroded area. An inconsistency of eroded area and fluid received is observed at toe-side clusters from DTS, DAS, and downhole images. This could be caused by a short erosion time at the toe-side clusters. In the completion design, only a few parameters show a strong impact on fluid distribution and perforation erosion.

Comparative Evaluation of Ultrasonography and Lateral Radiography in Nasal Fractures Diagnosis

Comparative Evaluation of Ultrasonography and Lateral Radiography in Nasal Fractures Diagnosis

AFFnet - a deep convolutional neural network for the detection of atypical femur fractures from anteriorposterior radiographs

Despite well-defined criteria for radiographic diagnosis of atypical femur fractures (AFFs), missed and delayed diagnosis is common. An AFF diagnostic software could provide timely AFF detection to prevent progression of incomplete or development of contralateral AFFs. In this study, we investigated the ability for an artificial intelligence (AI)-based application, using deep learning models (DLMs), particularly convolutional neural networks (CNNs), to detect AFFs from femoral radiographs. A labelled Australian dataset of pre-operative complete AFF (cAFF), incomplete AFF (iAFF), typical femoral shaft fracture (TFF), and non-fractured femoral (NFF) X-ray images in anterior-posterior view were used for training (N = 213, 49, 394, 1359, respectively). An AFFnet model was developed using a pretrained (ImageNet dataset) ResNet-50 backbone, and a novel Box Attention Guide (BAG) module to guide the model's scanning patterns to enhance its learning. All images were used to train and internally test the model using a 5-fold cross validation approach, and further validated by an external dataset. External validation of the model's performance was conducted on a Sweden dataset comprising 733 TFF and 290 AFF images. Precision, sensitivity, specificity, F1-score and AUC were measured and compared between AFFnet and a global approach with ResNet-50. Excellent diagnostic performance was recorded in both models (all AUC >0.97), however AFFnet recorded lower number of prediction errors, and improved sensitivity, F1-score and precision compared to ResNet-50 in both internal and external testing. Sensitivity in the detection of iAFF was higher for AFFnet than ResNet-50 (82 % vs 56 %). In conclusion, AFFnet achieved excellent diagnostic performance on internal and external validation, which was superior to a pre-existing model. Accurate AI-based AFF diagnostic software has the potential to improve AFF diagnosis, reduce radiologist error, and allow urgent intervention, thus improving patient outcomes.

Inter-Rater and Intrarater Reliability of Radiographs in the Diagnosis of Pediatric Scaphoid Fractures.

Pediatric scaphoid fractures can be challenging to diagnose on plain radiograph. Rates of missed scaphoid fractures can be as high as 30% to 37% on initial imaging and overall sensitivity ranging from 21% to 97%. Few studies, however, have examined the reliability of radiographs in the diagnosis of scaphoid fractures, and none are specific to the pediatric population. Reliability, both between different specialists and for individual raters, may elucidate some of the diagnostic challenges. We conducted a 2-iteration survey of pediatric orthopedic surgeons, plastic surgeons, radiologists, and emergency physicians at a tertiary children's hospital. Participants were asked to assess 10 series of pediatric wrist radiographs for evidence of scaphoid fracture. Inter-rater and intrarater reliability was calculated using the intraclass correlation coefficient of 2.1. Forty-two respondents were included in the first iteration analysis. Inter-rater reliability between surgeons (0.66; 95% confidence interval, 0.43-0.87), radiologists (0.76; 0.55-0.92), and emergency physicians (0.65; 0.46-0.86) was "good" to "excellent." Twenty-six respondents participated in the second iteration for intrarater reliability (0.73; 0.67-0.78). Sensitivity (0.75; 0.69-0.81) and specificity (0.78; 0.71-0.83) of wrist radiographs for diagnosing scaphoid fractures were consistent with results in other studies. Both inter-rater and intrarater reliability for diagnosing pediatric scaphoid fractures on radiographs was good to excellent. No significant difference was found between specialists. Plain radiographs, while useful for obvious scaphoid fractures, are unable to reliably rule out subtle fractures routinely. Our study demonstrates that poor sensitivity stems from the test itself, and not rater variability.

Myocardial Injury in Patients with Hip Fracture: A HIP ATTACK Randomized Trial Substudy.

Myocardial injury after a hip fracture is common and has a poor prognosis. Patients with a hip fracture and myocardial injury may benefit from accelerated surgery to remove the physiological stress associated with the hip fracture. This study aimed to determine if accelerated surgery is superior to standard care in terms of the 90-day risk of death in patients with a hip fracture who presented with an elevated cardiac biomarker/enzyme measurement at hospital arrival. The HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) trial was a randomized controlled trial designed to determine whether accelerated surgery for hip fracture was superior to standard care in reducing death or major complications. This substudy is a post-hoc analysis of 1392 patients (from the original study of 2970 patients) who had a cardiac biomarker/enzyme measurement (>99.9% had a troponin measurement and thus "troponin" is the term used throughout the paper) at hospital arrival. The primary outcome was all-cause mortality. The secondary composite outcome included all-cause mortality and non-fatal myocardial infarction, stroke, and congestive heart failure 90 days after randomization. Three hundred and twenty-two (23%) of the 1392 patients had troponin elevation at hospital arrival. Among the patients with troponin elevation, the median time from hip fracture diagnosis to surgery was 6 hours (interquartile range [IQR] = 5 to 13) in the accelerated surgery group and 29 hours (IQR = 19 to 52) in the standard care group. Patients with troponin elevation had a lower risk of mortality with accelerated surgery compared with standard care (17 [10%] of 163 versus 36 [23%] of 159; hazard ratio [HR] = 0.43 [95% confidence interval (CI) = 0.24 to 0.77]) and a lower risk of the secondary composite outcome (23 [14%] of 163 versus 47 [30%] of 159; HR = 0.43 [95% CI = 0.26 to 0.72]). One in 5 patients with a hip fracture presented with myocardial injury. Accelerated surgery resulted in a lower mortality risk than standard care for these patients; however, these findings need to be confirmed. Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.

Clinical Examination and Diagnosis of Nasal Bone Fracture; Is There Really a Need for X-ray Nasal Bone?

Objective: To evaluate the role of clinical examination in diagnosing nasal bone fracture. Methodology: This Prospective Observational study was carried out in the departments of Otolaryngology-Head and Neck Surgery and Radiology at the Pakistan Institute of Medical Sciences, Islamabad, from Jan 2022 to Dec 2023. About 1000 patients of nose trauma patients coming to ENT emergency were evaluated clinically by thorough nose examination by ENT surgeon and radiologically by X-ray nasal bone both lateral and anteroposterior view. Based on examination if nasal bone fracture was suspected patient was referred to radiology department for X-ray nasal bone which was reported by radiologist if the bone is fractured or not. The clinical findings were correlated with X-ray reports to find out if there really is a need for X-ray nasal bone for diagnosing nasal bone fracture. The diagnostic accuracy of clinical examination was calculated. Results: When clinical and radiological findings were compared regarding the diagnosis of nasal bone fracture a statistically significant association was found between the two (p=&lt;0.001) showing patients with clinical suspicion of fracture actually had fracture on X-ray. The diagnostic accuracy of clinical examination was very high with Positive Predictive Value, Negative Predictive Value, Sensitivity, Specificity, False Negative Rate and False Positive Rate being 96.1%, 93%, 88.5%, 97.7%, 11.5% and 2.3% respectively. Conclusion: We concluded that almost all patients with suspected nasal bone fracture actually had fractures on X-ray. Fractured nasal bone can correctly be diagnosed clinically by ENT surgeon and there is no real need for X-ray nasal bone just for diagnosing nasal bone fracture.

3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population.

To evaluate the feasibility of acquiring vertebral height from chest low-dose computed tomography (LDCT) images using an artificial intelligence (AI) system based on 3D U-Net vertebral segmentation technology and the correlation and features of vertebral morphology with sex and age of the Chinese population. Patients who underwent chest LDCT between September 2020 and April 2023 were enrolled. The Altman and Pearson's correlation analyses were used to compare the correlation and consistency between the AI software and manual measurement of vertebral height. The anterior height (Ha), middle height (Hm), posterior height (Hp), and vertebral height ratios (VHRs) (Ha/Hp and Hm/Hp) were measured from T1 to L2 using an AI system. The VHR is the ratio of Ha to Hp or the ratio of Hm to Hp of the vertebrae, which can reflect the shape of the anterior wedge and biconcave vertebrae. Changes in these parameters, particularly the VHR, were analysed at different vertebral levels in different age and sex groups. The results of the AI methods were highly consistent and correlated with manual measurements. The Pearson's correlation coefficients were 0.855, 0.919, and 0.846, respectively. The trend of VHRs showed troughs at T7 and T11 and a peak at T9; however, Hm/Hp showed slight fluctuations. Regarding the VHR, significant sex differences were found at L1 and L2 in all age bands. This innovative study focuses on vertebral morphology for opportunistic analysis in the mainland Chinese population and the distribution tendency of vertebral morphology with ageing using a chest LDCT aided by an AI system based on 3D U-Net vertebral segmentation technology. The AI system demonstrates the potential to automatically perform opportunistic vertebral morphology analyses using LDCT scans obtained during lung cancer screening. We advocate the use of age-, sex-, and vertebral level-specific criteria for the morphometric evaluation of vertebral osteoporotic fractures for a more accurate diagnosis of vertebral fractures and spinal pathologies.

Diagnostic Accuracy of Ultra-Low Dose CT Compared to Standard Dose CT for Identification of Fresh Rib Fractures by Deep Learning Algorithm.

The present study aimed to evaluate the diagnostic accuracy of ultra-low dose computed tomography (ULD-CT) compared to standard dose computed tomography (SD-CT) in discerning recent rib fractures using a deep learning algorithm detection of rib fractures (DLADRF). A total of 158 patients undergoing forensic diagnosis for rib fractures were included in this study: 50 underwent SD-CT, and 108 were assessed using ULD-CT. Junior and senior radiologists independently evaluated the images to identify and characterize the rib fractures. The sensitivity of rib fracture diagnosis by radiologists and radiologist + DLADRF was better using SD-CT than ULD-CT. However, the diagnosis sensitivity of DLADRF using ULD-CT alone was slightly more than SD-CT. Nonetheless, no substantial differences were observed in specificity, positive predictive value, and negative predictive value between SD-CT and ULD-CT by the same radiologist, radiologist + DLADRF, and DLADRF (P > 0.05). The area under the curve (AUC) of receiver operating characteristic indicated that senior radiologist + DLADRF was significantly better than senior and junior radiologists, junior radiologists + DLADRF, and DLADRF alone using SD-CT or ULD-CT (all P < 0.05). Also, junior radiologists + DLADRF was better with ULD-CT than senior and junior radiologists (P < 0.05). The AUC of the rib fracture diagnosed by senior radiologists did not differ from DLADRF using ULD-CT. Also, no significant differences were observed between junior + AI and senior and between junior and DLADRF using SD-CT. DLADRF enhanced the diagnostic performance of radiologists in detecting recent rib fractures. The diagnostic outcomes between SD-CT and ULD-CT across radiologists' experience and DLADRF did not differ significantly.