Medical Image Diagnosis Research Articles

Deep Learning Approaches for Medical Image Analysis and Diagnosis.

In addition to enhancing diagnostic accuracy, deep learning techniques offer the potential to streamline workflows, reduce interpretation time, and ultimately improve patient outcomes. The scalability and adaptability of deep learning algorithms enable their deployment across diverse clinical settings, ranging from radiology departments to point-of-care facilities. Furthermore, ongoing research efforts focus on addressing the challenges of data heterogeneity, model interpretability, and regulatory compliance, paving the way forseamless integration of deep learning solutions into routine clinical practice. As the field continues to evolve, collaborations between clinicians, data scientists, and industry stakeholders will be paramount in harnessing the full potential of deep learning for advancing medical image analysis and diagnosis. Furthermore, the integration of deep learning algorithms with other technologies, including natural language processing and computer vision, may foster multimodal medical data analysis and clinical decision support systems to improve patient care. The future of deep learning in medical image analysis and diagnosis is promising. With each success and advancement, this technology is getting closer to being leveraged for medical purposes. Beyond medical image analysis, patient care pathways like multimodal imaging, imaging genomics, and intelligent operating rooms or intensive care units can benefitfrom deep learning models.

Diagnosis of Medical Images Using Convolutional Neural Networks

Medical image diagnosis using Convolutional Neural Networks (CNNs) has emerged as a viable way to improve the accuracy and efficiency of disease identification and categorization in clinical settings. In this study, they look at how CNNs can be used to diagnose lung nodules from chest X-ray pictures, to provide insights into the technology's performance and future clinical applications. A dataset of 10,000 tagged chest X-ray pictures showing both benign and malignant lung nodules was obtained and preprocessed using standard methods. The dataset was used to construct and train a proprietary CNN architecture, which was then rigorously evaluated on distinct training, validation, and test sets. The CNN model showed good accuracy (94.8%), sensitivity (92.1%), specificity (96.5%), precision, recall, F1 score, and area under the ROC curve (AUC), indicating its robustness and generalization ability. These findings show that CNN-based diagnostic tools may help radiologists and physicians discover and diagnose lung cancer earlier, improving patient outcomes and optimizing healthcare delivery. However, difficulties such as interpretability, data privacy, and regulatory approval must be addressed before CNNs can be fully utilized in medical imaging. This study emphasizes CNNs' transformative significance in diagnostic medicine and the necessity for additional research and development to realize their full potential in clinical practice.

Studying the history of histopathology in preclinical medical education as a guide for the uniform integration of radiology in medical education

Radiology and pathology, though distinct fields within medical education, share a common foundation in their essential roles for accurate diagnosis and understanding of diseases. While pathology, particularly histopathology, has long been integrated into preclinical medical education in the United States, radiology education has traditionally been less emphasized. This paper examines the historical development of histopathology training in medical education and its central role, contrasting it with the comparatively peripheral position of radiology education. We explore the historical context of medical education in the United States, tracing the integration of histopathology following the Flexner Report of 1910. In contrast, radiology, emerging later as a specialized field, has faced challenges in achieving comparable integration into medical curricula. Despite the increasing importance of medical imaging in diagnosis and treatment, radiology education remains variable and often lacking in standardization across medical schools. We highlight the need for greater emphasis on radiology education to better prepare medical students for modern clinical practice, where medical imaging plays an increasingly pivotal role. A call for a comprehensive assessment of radiology education and advocacy for its integration into preclinical curricula is made, emphasizing the importance of collaboration between the radiology profession and accrediting bodies to ensure competence in imaging across medical specialties. As medical imaging continues to advance and become more integral to healthcare, it is imperative that medical education reflects this evolution by establishing radiology as a fundamental component of preclinical training.

Dynamic Weighting Translation Transfer Learning for Imbalanced Medical Image Classification.

Medical image diagnosis using deep learning has shown significant promise in clinical medicine. However, it often encounters two major difficulties in real-world applications: (1) domain shift, which invalidates the trained model on new datasets, and (2) class imbalance problems leading to model biases towards majority classes. To address these challenges, this paper proposes a transfer learning solution, named Dynamic Weighting Translation Transfer Learning (DTTL), for imbalanced medical image classification. The approach is grounded in information and entropy theory and comprises three modules: Cross-domain Discriminability Adaptation (CDA), Dynamic Domain Translation (DDT), and Balanced Target Learning (BTL). CDA connects discriminative feature learning between source and target domains using a synthetic discriminability loss and a domain-invariant feature learning loss. The DDT unit develops a dynamic translation process for imbalanced classes between two domains, utilizing a confidence-based selection approach to select the most useful synthesized images to create a pseudo-labeled balanced target domain. Finally, the BTL unit performs supervised learning on the reassembled target set to obtain the final diagnostic model. This paper delves into maximizing the entropy of class distributions, while simultaneously minimizing the cross-entropy between the source and target domains to reduce domain discrepancies. By incorporating entropy concepts into our framework, our method not only significantly enhances medical image classification in practical settings but also innovates the application of entropy and information theory within deep learning and medical image processing realms. Extensive experiments demonstrate that DTTL achieves the best performance compared to existing state-of-the-art methods for imbalanced medical image classification tasks.

Prediction of Chest X-Ray Abnormalities using Ensemble Learning

Abstract: Chest X-rays are a cornerstone of medical imaging, enabling rapid and cost-effective diagnosis of numerous chest pathologies. However, limitations in radiologist availability and long wait times can significantly delay diagnoses, potentially impacting patient outcomes. This study explores the potential of deep learning to address these challenges. Deep learning algorithms can analyse medical images and identify patterns associated with various diseases. In this study, Various deep learning models were trained and evaluated, including DenseNet121, EfficientNetB1, Xception, and an ensemble model combining EfficientNetB1 and Xception, using a random sample of 5,606 chest X-ray images from the National Institutes of Health (NIH) chest X-ray dataset. The ensemble model achieved the most promising results, demonstrating an accuracy of 72.66% and an AUC-ROC (Area Under the Receiver Operating Characteristic Curve) of 76.05%

BAF-Net: bidirectional attention-aware fluid pyramid feature integrated multimodal fusion network for diagnosis and prognosis

Objective. To go beyond the deficiencies of the three conventional multimodal fusion strategies (i.e. input-, feature- and output-level fusion), we propose a bidirectional attention-aware fluid pyramid feature integrated fusion network (BAF-Net) with cross-modal interactions for multimodal medical image diagnosis and prognosis. Approach. BAF-Net is composed of two identical branches to preserve the unimodal features and one bidirectional attention-aware distillation stream to progressively assimilate cross-modal complements and to learn supplementary features in both bottom-up and top-down processes. Fluid pyramid connections were adopted to integrate the hierarchical features at different levels of the network, and channel-wise attention modules were exploited to mitigate cross-modal cross-level incompatibility. Furthermore, depth-wise separable convolution was introduced to fuse the cross-modal cross-level features to alleviate the increase in parameters to a great extent. The generalization abilities of BAF-Net were evaluated in terms of two clinical tasks: (1) an in-house PET-CT dataset with 174 patients for differentiation between lung cancer and pulmonary tuberculosis. (2) A public multicenter PET-CT head and neck cancer dataset with 800 patients from nine centers for overall survival prediction. Main results. On the LC-PTB dataset, improved performance was found in BAF-Net (AUC = 0.7342) compared with input-level fusion model (AUC = 0.6825; p < 0.05), feature-level fusion model (AUC = 0.6968; p = 0.0547), output-level fusion model (AUC = 0.7011; p < 0.05). On the H&N cancer dataset, BAF-Net (C-index = 0.7241) outperformed the input-, feature-, and output-level fusion model, with 2.95%, 3.77%, and 1.52% increments of C-index (p = 0.3336, 0.0479 and 0.2911, respectively). The ablation experiments demonstrated the effectiveness of all the designed modules regarding all the evaluated metrics in both datasets. Significance. Extensive experiments on two datasets demonstrated better performance and robustness of BAF-Net than three conventional fusion strategies and PET or CT unimodal network in terms of diagnosis and prognosis.

Dynamic Attribute-guided Few-shot Open-set Network for medical image diagnosis

The scarcity of data on rare diseases poses a significant challenge to the development of diagnostic systems. While few-shot learning (FSL) offers promise in low-data regimes, it often struggles in open-set scenarios, failing to identify unknown diseases. In this paper, we introduce a Dynamic Attribute-guided Few-shot Open-set Network (DAFON), representing the first effort to simultaneously address closed-set classification and open-set recognition in rare disease diagnosis. To alleviate incomprehensive category knowledge stemming from data scarcity, we propose a Global Attribute Generator to create attributes and produce image attribute activations for closed-set data as auxiliary information. An attribute space is then constructed and employed to generate the pseudo open-set attribute activations using a designed Open-set Data Sampler. By incorporating closed-set and open-set attribute activations as conditions, we propose a Dynamic Attribute Guided Alignment module to align feature space with attribute space, so as to derive feature space with intra-class compactness for closed-set and open-set classes. Our DAFON achieves state-of-the-art performance on two public medical image datasets, demonstrating its effectiveness for FSOSR in medical image diagnosis.

3D medical image segmentation based on semi-supervised learning using deep co-training

In recent years, artificial intelligence has been applied to 3D COVID-19 medical image diagnosis, which reduces detection costs and missed diagnosis rates with higher predictive accuracy, and diagnostic efficiency. However, the limited size and low quality of clinical 3D medical image samples have hindered the segmentation performance of 3D models. Therefore, we propose a 3D medical image segmentation model based on semi-supervised learning using co-training. Multi-view and multi-modal images are generated using spatial flipping and windowing techniques to enhance the spatial diversity of 3D image samples. A pseudo label generation module based on confidence-weights is employed to generate reliable pseudo labels for non-annotated data, thereby increasing the sample size and reducing overfitting. The proposed approach utilizes a three-stage training process: firstly, training a single network based on annotated data; secondly, incorporating non-annotated data to train a dual-modal network and generate pseudo labels; finally, jointly training six models in three dimensions using both annotated and pseudo labels generated from multi-view and multi-modal images, aiming to enhance segmentation accuracy and generalization performance. Additionally, a consistency regularization loss is applied to reduce noises and accelerate convergence of the training. Moreover, a heatmap visualization method is employed to focus on the attention of features at each stage of training, providing effective reference for clinical diagnosis. Experiments were conducted on an open dataset of 3D COVID-19 CT samples and a non-annotated dataset from TCIA, including 771 NIFTI-format CT images from 661 COVID-19 patients. The results of 5-fold cross-validation show that the proposed model achieves a segmentation accuracy of Dice=73.30 %, ASD=10.633, Sensitivity=63.00 %, and Specificity=99.60 %. Compared to various typical semi-supervised learning 3D segmentation models, it demonstrates better segmentation accuracy and generalization performance.

Application of artificial intelligence digital holography technology based on medical sensors in the development of medical image fusion

With the rapid development of artificial intelligence and medical technology, sensor technology, as an important tool to obtain medical data, provides a wealth of physiological parameter information, but the traditional medical image fusion methods are difficult to make full use of the information provided by sensors. Therefore, this paper aims to explore the application of artificial intelligence digital holographic technology based on medical sensor in medical image fusion, and improve the accuracy and effect of medical image diagnosis and treatment. Based on the physiological parameter data obtained by medical sensor, combined with deep learning and image processing algorithm, a medical image fusion method based on artificial intelligence digital holography technology was proposed. The method uses the physiological parameter information provided by the sensor and combines multiple medical image sources to realize holographic medical image presentation. The experimental results show that the artificial intelligence digital holographic technology based on medical sensor can effectively improve the resolution and information content of medical image fusion. Compared with traditional medical image fusion methods, this method has higher image quality and more accurate diagnosis results.

Vision, body and interpretation in medical imaging diagnostics.

This article explores the profound impact of visualism and visual perception in the context of medical imaging diagnostics. It emphasizes the intricate interplay among vision, embodiment, subjectivity, language, and historicity within the realm of medical science and technology, with a specific focus on image consciousness. The study delves into the role of subjectivity in perception, facilitating the communication of opacity and historicity to the perceiving individual. Additionally, it scrutinizes the image interpretation process, drawing parallels to text interpretation and highlighting the influence of personal biases and individuality in medical practice. By revisiting Husserl's conceptualization of "image consciousness" and introducing the notion of "image theme", the paper seeks to establish a theoretical framework for making sense of images within the context of technological interpretation. A key objective is to enhance the phenomenology of technology through a systematic analysis of medical imaging diagnosis, contributing to an expanded epistemological foundation for medical practice. The article recognizes that the construction of medical knowledge incorporates subjective elements, especially within a historical context. The interpretation of images involves both instrumental and expert interpretation, with human subjectivity playing a crucial role. The article asserts that human creativity and conscious engagement are indispensable in interpreting all medical images.

Contrastive Learning Penalized Cross-Entropy with Diversity Contrastive Search Decoding for Diagnostic Report Generation of Reduced Token Repetition

Medical imaging description and disease diagnosis are vitally important yet time-consuming. Automated diagnosis report generation (DRG) from medical imaging description can reduce clinicians’ workload and improve their routine efficiency. To address this natural language generation task, fine-tuning a pre-trained large language model (LLM) is cost-effective and indispensable, and its success has been witnessed in many downstream applications. However, semantic inconsistency of sentence embeddings has been massively observed from undesirable repetitions or unnaturalness in text generation. To address the underlying issue of anisotropic distribution of token representation, in this study, a contrastive learning penalized cross-entropy (CLpCE) objective function is implemented to enhance the semantic consistency and accuracy of token representation by guiding the fine-tuning procedure towards a specific task. Furthermore, to improve the diversity of token generation in text summarization and to prevent sampling from unreliable tail of token distributions, a diversity contrastive search (DCS) decoding method is designed for restricting the report generation derived from a probable candidate set with maintained semantic coherence. Furthermore, a novel metric named the maximum of token repetition ratio (maxTRR) is proposed to estimate the token diversity and to help determine the candidate output. Based on the LLM of a generative pre-trained Transformer 2 (GPT-2) of Chinese version, the proposed CLpCE with DCS (CLpCEwDCS) decoding framework is validated on 30,000 desensitized text samples from the “Medical Imaging Diagnosis Report Generation” track of 2023 Global Artificial Intelligence Technology Innovation Competition. Using four kinds of metrics evaluated from n-gram word matching, semantic relevance, and content similarity as well as the maxTRR metric extensive experiments reveal that the proposed framework effectively maintains semantic coherence and accuracy (BLEU-1, 0.4937; BLEU-2, 0.4107; BLEU-3, 0.3461; BLEU-4, 0.2933; METEOR, 0.2612; ROUGE, 0.5182; CIDER, 1.4339) and improves text generation diversity and naturalness (maxTRR, 0.12). The phenomenon of dull or repetitive text generation is common when fine-tuning pre-trained LLMs for natural language processing applications. This study might shed some light on relieving this issue by developing comprehensive strategies to enhance semantic coherence, accuracy and diversity of sentence embeddings.

Application of deep learning radiomics in oral squamous cell carcinoma–Extracting more information from medical images using advanced feature analysis

ObjectiveTo conduct a systematic review with meta-analyses to assess the recent scientific literature addressing the application of deep learning radiomics in oral squamous cell carcinoma (OSCC). Materials and methodsElectronic and manual literature retrieval was performed using PubMed, Web of Science, EMbase, Ovid-MEDLINE, and IEEE databases from 2012 to 2023. The ROBINS-I tool was used for quality evaluation; random-effects model was used; and results were reported according to the PRISMA statement. ResultsA total of 26 studies involving 64,731 medical images were included in quantitative synthesis. The meta-analysis showed that, the pooled sensitivity and specificity were 0.88 (95 %CI: 0.87∼0.88) and 0.80 (95 %CI: 0.80∼0.81), respectively. Deeks’ asymmetry test revealed there existed slight publication bias (P = 0.03). ConclusionsThe advances in the application of radiomics combined with learning algorithm in OSCC were reviewed, including diagnosis and differential diagnosis of OSCC, efficacy assessment and prognosis prediction. The demerits of deep learning radiomics at the current stage and its future development direction aimed at medical imaging diagnosis were also summarized and analyzed at the end of the article.

SAM-IE: SAM-based image enhancement for facilitating medical image diagnosis with segmentation foundation model

The Segment Anything Model (SAM) is a large-scale model developed for general segmentation tasks in computer vision. Trained on a substantial dataset, SAM can accurately segment various objects in natural scene images. However, due to significant semantic differences between medical and natural images, directly applying SAM to medical image segmentation does not yield optimal results. Therefore, effectively utilizing such a comprehensive foundation model for medical image analysis is an emerging research topic. Despite SAM’s current suboptimal performance in medical image segmentation, it shows preliminary recognition and localization of tissues and lesions that radiologists focus on in medical images. This implies that SAM’s generated masks, features, and stability scores hold potential value for medical image diagnosis. Therefore, based on the model output of SAM, this study introduces a SAM-based Image Enhancement (SAM-IE) method for disease diagnosis. Targeting popular medical image classification models (e.g., ResNet50 and Swin Transformer), SAM-IE is proposed to enhance image inputs by combining the binary mask and contour mask generated by SAM with the original image to create attention maps, thereby improving diagnostic performance. To validate the effectiveness of SAM-IE for diagnosis, experiments were conducted on four medical image datasets for eight classification tasks. The results demonstrate the effectiveness of our proposed SAM-IE model, showcasing SAM’s potential value in medical image classification. This study provides a feasible approach for integrating SAM into disease diagnosis.

Application Exploration of Medical Image-aided Diagnosis of Breast Tumour Based on Deep Learning.

Nowadays, people attach increasing importance to accurate and timely disease diagnosis and personalized treatment. Because of the uncertainty and latency of the pathogenesis, it is difficult to detect breast tumour early. With higher resolution, magnetic resonance imaging (MRI) has become an important method for early detection of cancer in recent years. At present, DL technology can automatically study imaging features of different depths. This work aimed to use DL to study medical image-assisted diagnosis. The image data were collected from the patients. ROI (region of interest) containing the complete tumor area in the medical image was generated. The ROI image was extracted, and the extracted feature data were expanded. By constructing a three-dimensional (3D) CNN model, the evaluation indicators of breast tumour diagnosis results have been proposed. In the experiment part, 3D CNN model and other models have been used to diagnose the medical image of breast tumour. The 3D CNN model exhibited good ROI region extraction effect and breast tumor image diagnosis effect, and the average diagnostic accuracy of breast tumor image diagnosis was 0.736, which has been found to be much higher than other models and could be applied to breast tumor medical image-aided diagnosis. The 3D CNN model has been trained by combining the two-dimensional CNN training mode, and the evaluation index of diagnostic results has been established. The experimental part verified the medical image diagnosis effect of the 3D CNN model. The model had exhibited a high ROI region extraction effect and breast tumor image diagnosis effect.

SC-Net: Symmetrical conical network for colorectal pathology image segmentation

Background and ObjectiveImage segmentation of histopathology of colorectal cancer is a core task of computer aided medical image diagnosis system. Existing convolutional neural networks generally extract multi-scale information in linear flow structures by inserting multi-branch modules, which is difficult to extract heterogeneous semantic information under multi-level and different receptive field and tough to establish context dependency among different receptive field features. MethodsTo address these issues, we propose a symmetric spiral progressive feature fusion encoder-decoder network called the Symmetric Conical Network (SC-Net). First, we design a Multi-scale Feature Extraction Block (MFEB) matching with the Symmetric Conical Network to obtain multi-branch heterogeneous semantic information under different receptive fields, so as to enrich the diversity of extracted feature information. The encoder is composed of MFEB through spiral and multi-branch arrangement to enhance context dependence between different information flow. Secondly, the information loss of contour, color and others in high-level semantic information through causally stacking MFEB, the Feature Mapping Layer (FML) is designed to map low-level features to high-level semantic features along the down-sampling branch and solve the problem of insufficient global feature extraction in deep levels. ResultsThe SC-Net was evaluated on our self-constructed colorectal cancer dataset, a publicly available breast cancer dataset and a polyp dataset. The results revealed that the mDice of segmentation reached 0.8611, 0.7259 and 0.7144. We compare our model with the state-of-art semantic segmentation UNet++, PSPNet, Attention U-Net, R2U-Net and other advanced segmentation networks. The experimental results demonstrate that we achieve the most advanced performance. ConclusionsThe results indicate that the proposed SC-Net excels in segmenting H&E stained pathology images, effectively preserving morphological features and spatial information even in scenarios with weak texture, poor contrast, and variations in appearance.

Adversarial Attacks on Medical Image Diagnosis Models And its Mitigation Techniques

Adversarial Attacks on Medical Image Diagnosis Models And its Mitigation Techniques

Machine Learning-Based Medical Imaging Detection and Diagnostic Assistance

With the development of medical technology, medical imaging technology plays an increasingly important role in diagnosing and monitoring diseases. At the same time, machine learning technology has shown strong capabilities in data processing and analysis, providing new possibilities for the detection and auxiliary diagnosis of medical images. This paper will deeply discuss the application of machine learning in medical images, especially the application of deep learning in medical images, and how to achieve effective medical image detection and auxiliary diagnosis through steps such as preprocessing, feature extraction, model training and optimization.

Machine learning-based medical imaging diagnosis in patients with temporomandibular disorders: a diagnostic test accuracy systematic review and meta-analysis.

Temporomandibular disorders (TMDs) are the second most common musculoskeletal condition which are challenging tasks for most clinicians. Recent research used machine learning (ML) algorithms to diagnose TMDs intelligently. This study aimed to systematically evaluate the quality of these studies and assess the diagnostic accuracy of existing models. Twelve databases (Europe PMC, Embase, etc.) and two registers were searched for published and unpublished studies using ML algorithms on medical images. Two reviewers extracted the characteristics of studies and assessed the methodological quality using the QUADAS-2 tool independently. A total of 28 studies (29 reports) were included: one was at unclear risk of bias and the others were at high risk. Thus the certainty of evidence was quite low. These studies used many types of algorithms including 8 machine learning models (logistic regression, support vector machine, random forest, etc.) and 15 deep learning models (Resnet152, Yolo v5, Inception V3, etc.). The diagnostic accuracy of a few models was relatively satisfactory. The pooled sensitivity and specificity were 0.745 (0.660-0.814) and 0.770 (0.700-0.828) in random forest, 0.765 (0.686-0.829) and 0.766 (0.688-0.830) in XGBoost, and 0.781 (0.704-0.843) and 0.781 (0.704-0.843) in LightGBM. Most studies had high risks of bias in Patient Selection and Index Test. Some algorithms are relatively satisfactory and might be promising in intelligent diagnosis. Overall, more high-quality studies and more types of algorithms should be conducted in the future. We evaluated the diagnostic accuracy of the existing models and provided clinicians with much advice about the selection of algorithms. This study stated the promising orientation of future research, and we believe it will promote the intelligent diagnosis of TMDs.

Medical CT image diagnosis and simulation of drug sedation during ultrasound-guided transbronchial needle aspiration process

CT image diagnosis is widely used in clinical practice, but the effect of drug sedation during bronchial aspiration has not been fully simulated and studied. The aim of this study was to simulate the effect of drug sedation in the process of transbronchial needle aspiration guided by medical CT images in order to explore its potential effect in clinical application. A diagnostic model based on medical CT images was established to simulate the sedation of drugs during bronchial needle aspiration. A series of parameters of sedation, including dose, route of administration and drug selection, were used to better simulate the actual situation. The simulation experiment observed that the effect of drug sedation in the process of bronchial needle aspiration under the guidance of medical CT image diagnosis can effectively relieve the pain and discomfort of patients, and improve the success rate of the operation process, and drug sedation can also reduce the occurrence of postoperative infection and complications. Therefore, under the guidance of medical CT image diagnosis, the simulation of drug sedation during the process of transbronchial needle aspiration can help doctors better perform relevant operations and improve the safety and success rate of surgery.

3D-CAM: a novel context-aware feature extraction framework for neurological disease classification.

In clinical practice and research, the classification and diagnosis of neurological diseases such as Parkinson's Disease (PD) and Multiple System Atrophy (MSA) have long posed a significant challenge. Currently, deep learning, as a cutting-edge technology, has demonstrated immense potential in computer-aided diagnosis of PD and MSA. However, existing methods rely heavily on manually selecting key feature slices and segmenting regions of interest. This not only increases subjectivity and complexity in the classification process but also limits the model's comprehensive analysis of global data features. To address this issue, this paper proposes a novel 3D context-aware modeling framework, named 3D-CAM. It considers 3D contextual information based on an attention mechanism. The framework, utilizing a 2D slicing-based strategy, innovatively integrates a Contextual Information Module and a Location Filtering Module. The Contextual Information Module can be applied to feature maps at any layer, effectively combining features from adjacent slices and utilizing an attention mechanism to focus on crucial features. The Location Filtering Module, on the other hand, is employed in the post-processing phase to filter significant slice segments of classification features. By employing this method in the fully automated classification of PD and MSA, an accuracy of 85.71%, a recall rate of 86.36%, and a precision of 90.48% were achieved. These results not only demonstrates potential for clinical applications, but also provides a novel perspective for medical image diagnosis, thereby offering robust support for accurate diagnosis of neurological diseases.