Heat stress is a climate extreme that impacts cattle health, fertility, feed intake, production, and well-being. In Vanuatu, the beef industry is crucial to local livelihoods and the nation’s economy, thus the objective of this study was to examine the impact of heat stress on cattle health and production. This study uses the Heat Load Index (HLI) and Accumulated Heat Load (AHL) as proxies to assess the impact of heat stress on cattle in Vanuatu over a 30-year period (1994–2023), using the fifth generation of the European Centre for Medium-Range Weather Forecasts (ECMWF) atmospheric reanalysis of the global climate (ERA5) data. The analysis examines historical patterns of heat stress in cattle across Vanuatu, identifying more instances of heat stress occurring during the wet season due to characteristically elevated temperatures, humidity, and low wind speeds. Findings also suggest that El Niño events may increase the intensity and duration of heat stress events. These insights inform the development of an Early Warning System for heat stress in cattle, establishing a crucial foundation for targeted adaptation strategies aimed at enhancing the resilience and sustainability of Vanuatu’s beef industry to climate variability and change.