The purpose of this research is to develop a model of the quality assurance information system based on an integration of BAN-PT accreditation and ISO 9001: 2008 for ISO-certified higher education institutions. Problems that arise when the higher education has been certified ISO 9001: 2008 and will carry out accreditation of study program based on BAN-PT. Another problem is that higher education institutions do not have an integrated model of the quality assurance information system based on the integration of BAN-PT Accreditation and ISO 9001: 2008. This study is the next stage of previous research showing a framework of accreditation results of BANT-PT and ISO 9001: 2008. This National Strategy Research for Institutions is a type of applied research that uses a qualitative approach. The result of this research is a model of Quality Assurance Information System (QAIS) based on an integration of BAN-PT accreditation and ISO 0001: 2008 for ISO-certified higher education institutions. This QAIS modeling will later facilitate software application development at the next stage of research in the future. This Quality Assurance Information System will be able to support the change management of study program to improve the accreditation standard of study program significantly.