The purpose of this study involves the development of new methodological approaches to solving the urgent problem of implementing the concept of sustainable development in the country, its regions, industries and enterprises. It is clear, that the specifics of the mining activity predetermines both the special nature of interests, contradictions and industrial relations, developing in this area, and the adequacy of the approach to setting and solving the tasks of achieving sustainable development goals (SDGs). They consist, firstly, in determining the influence of investment processes on the formation of a balanced system of sustainable development of the region, in which financial and economic goals would be harmonized with environmental and social processes, and, secondly, in developing a methodology and a specific method of diagnostics and assessment systems of factors, that manifest themselves as barriers and restrictions, threats and challenges. At the end, the obtained results of the study should contribute to significant progress in solving the problem of attracting investments and implementing the concept of sustainable development of mining regions.