The article considers tendencies, peculiarities and problems of formation of geographical, commodity, industrial structure of export and import of goods, by the degree of their technological intensity (manufacturing), between the Eurasian Economic Union (EAEU) and regional integration groups, Association of Southeast Asian Nations (ASEAN), European Union (EU) and Shanghai Cooperation Organization (SCO). The analysis was conducted using UNCTAD statistics on the digit commodity codes of the International Standard Trade Classification (SATC). The directions of trade diversification are offered. The countries for access of the EAEU to the markets of manufactures of ASEAN, EU and SCO are selected. Positive changes in the structure of trade, especially with ASEAN as well as the SCO, are noted. On the basis of calculation of index of intra-industry trade the sensitive goods are allocated, in trade by which EAEU competes with integration groups, the directions of development of industrial cooperation and inclusion in Global Value Chains (GVC) are offered. The presence of a large number of sensitive positions in trade with China, India, Poland, Great Britain, France, Vietnam, Singapore is noted. Prospective export products have been identified into these integration groups, recommendations to reduce barriers to trade have been developed.