Axis Determination Research Articles

Ground calibration and in-orbit performance of the time-resolved soft x-ray spectrometer on board XPNAV-1

The time-resolved soft x-ray spectrometer (TSXS) aboard on the X-ray Pulsar Navigation Test Satellite is an x-ray timing spectrometer covering the energy range of 0.5 to 10 keV. It is China’s first focusing x-ray telescope launched into space orbit. The optical system of TSXS is an x-ray grazing incidence focusing system with a field of view 15 arc min, which is nested with 4 parabolic mirrors with a focal length of 1150 mm. The focal plane detector of TSXS uses a silicon drift detector. From April to June 2016, ground calibration was carried out on TSXS, including the optical axis determination, calibration of energy linearity and energy resolution, calibration of time resolution and photon arrival time accuracy, and calibration of mirrors’ reflectivity. After the launch on November 10, 2016, the in-orbit calibration and performance verification of the telescope was carried out, including the optical axis determination, the performance of energy response, the performance of time accuracy, the calibration of effective area, and the evaluation of telescope sensitivity. After calibration and verification on the ground and in orbit, the photon energy measurement error of the telescope is better than 0.5% at energies above 1.5 keV, the energy resolution is better than 156 eV at 6.4 keV, the time resolution is <1 μs, the photon arrival time measurement accuracy is <302 ns, and the telescope in-orbit background is <4.16 ± 1.42 × 10 − 3 photons / s (0.5 to 3 keV, 40°N to 40°S, not including South Atlantic Anomaly). The telescope has an in-orbit observation sensitivity of 2.09 × 10 − 3 photons / cm2 / s / keV (0.5 to 3 keV, T = 1000 s, and nσ = 5).

Development and Application of a Motion Analysis Protocol for the Kinematic Evaluation of Basic and Functional Hand and Finger Movements Using Motion Capture in a Clinical Setting—A Repeatability Study

The purpose of this study was to develop a motion analysis protocol that allows the simultaneous assessment of all hand and finger joint movements. The objective was to demonstrate repeatability for future clinical applications in functional assessments. This study includes selection of marker positions, movement tasks, kinematic approaches and a comparison of the two most commonly used finger marker sets. By using a test–retest measurement of the range of motion in twenty healthy volunteers, the repeatability of the developed protocol was validated. Estimated errors of the presented method ranged from 1.2° to 6.4°. Finger joint angles derived from the marker set with two markers per segment showed better repeatability (3.7°) than with markers located on the joints (5.1°). Given the high repeatability found, the presented method appears to be suitable for clinical applications. For the fingers, measurement repeatability can be improved by using at least two markers per segment. Within this study, advanced kinematic approaches, such as functional determination of joint centers and axes, are applied to the analysis of hand movements. The provided standard values and estimate of the minimal detectable differences provide a valuable basis for meaningful data interpretation and may be used for future comparison with other protocols.

A Synergy and Struggle of EPR, Magnetometry and NMR: A Case Study of Magnetic Interaction Parameters in a Six-Coordinate Cobalt(II) Complex.

Herein, we combine for the first time SQUID magnetometry, cw-EPR, THz-EPR, and paramagnetic NMR spectroscopies to study the magnetic properties of a high-spin cobalt(II) heteroscorpionate complex. Complementary information provided by these methods allowed precise determination of the magnetic interaction parameters, thereby removing the ambiguity inherit to single-method studies. We systematically investigate the extent to which information about the magnetic interaction parameters can be deduced from reduced data sets. The detailed study revealed significant different magnetic properties in solid state and solution. To further exploit the information content of the solution NMR experimental results, we introduce the new concept of reduced paramagnetic shift. It allows for the determination of the magnetic axes and, subsequently, full NMR signal assignment. It is shown that even in complicated cases, in which common NMR analytics (integral intensities, relaxation factors, etc.) fail, it yields robust results.

A screw theory approach to compute instantaneous rotation axes of indeterminate spherical linkages

This paper presents a screw theory approach for the computation of the instantaneous rotation axes of indeterminate spherical linkages. Since the last part of the XIX century, the determination of the instantaneous rotation, or velocity, centers of planar mechanisms has been studied using the Aronhold-Kennedy theorem, extended to the spatial case until the second part of last century. In the beginning of the XX century, it was found that there were planar mechanisms for which the application of the Aronhold-Kennedy theorem was unable to find all the instantaneous rotation centers; these mechanisms where denominated complex or indeterminate. The beginning of this century saw a renewed interest on the complex or indeterminate mechanisms, both planar and spherical; and very soon, taken advantage of the results obtained for planar mechanisms, there were several methods for the determination of the indeterminate instantaneous rotation axes. The new screw theory approach, presented here, provides a more straightforward method for setting up the equations; furthermore, the algebraic equations to be solved are simpler than the ones published up to date. In addition, the method is part of a comprehensive method for the determination of the instantaneous screw axes of spatial mechanisms or their many special cases. The method is based on a systematic application of screw theory, which is isomorphic to the Lie algebra, se(3), of the Euclidean group, SE(3), and the invariant symmetric bilinear forms defined on se(3).

Three-dimensional morphological analysis of the femoral neck torsion angle\u2014an anatomical study

BackgroundThe femoral neck torsion angle (FNTA) is an important but often neglected parameter in assessments of the anatomical morphology of the femoral neck, which is often confused with the femoral neck anteversion angle (FNAA) in the current literature. Currently, the measurement methods reported in the literature all adopt the naked eye or two-dimensional (2D) visualization method, and the measurement parameters and details are not clearly defined. The objection of this research was to provide a reliable 3D method for determining the femoral neck axis, to improve the measurement method of the FNTA, and to analyze the anatomical and clinical significance of the results.MethodsComputed tomography (CT) data of 200 patients who received a lower extremity CT angiography examination were selected, and the bilateral femurs were reconstructed with three dimensional CT (3D CT). First, the 3D axis of the femoral neck was built. Second, the long axis of the cross section the femoral neck isthmus (FNI) and femoral neck basilar part (FNB) were confirmed by the “inertia axes” method, and the plane consisting of the long axis of the cross-section and the center of the femoral head was defined as the long axial plane. Third, the coronal plane of the proximal femur was determined through the long axis of the proximal femur and the femoral coronal. Finally, the FNTAs (the angles between the long axial planes and the coronal plane of the proximal femur) of FNI and FNB were measured. The size of FNTA was compared between the sexes and sides and different locations, the correlation between the parameters and age, height, and weight were evaluated.ResultsThe difference in FNTA was statistically significant between the isthmus and the basilar part (isthmus 30.58 ± 8.90° vs. basilar part 23.79 ± 3.98°; p < 0.01). Significant difference in the FNTA was observed between the sexes (males 31.99 ± 9.25° vs. females 27.49 ± 7.19°; p < 0.01). The increase in FNTA from the basilar part to the isthmus was 6.79 ± 8.06°, and the male (7.87 ± 8.57°) was greater than the female (4.44 ± 6.23°, p < 0.01). However, no significant difference in the values was observed between sides. Height exerted the greatest effect on the FNTA according to the correlation analysis (r = 0.255, p< 0.001).ConclusionsThis study found a reliable 3D method for the determination of the femoral neck axis improved the measurement method of the FTNTA and made it more accurate and repeatable. The results provided a methodological basis and theoretical support for the research and development of internal fixation device for femoral neck fracture and the spatial configuration of implants in treatment. And the optimal opening point of the femoral medullary cavity was recommended to locate at the posterior position of the top of the femoral neck cross-section during hip replacement.

Determination, Reproducibility and Illustration of the Helical Axes of the knee after Total Arthroplasty

Determination, Reproducibility and Illustration of the Helical Axes of the knee after Total Arthroplasty

Determination of the tram track axis using a multi receiver GNSS measurement system

This article refers to research, that has been conducted by an interdisciplinary research team from the Gdańsk University of Technology and the Maritime University in Gdynia since 2009. These investigation concerns the determination of a railway track axis using the mobile satellite measurement technique. Following the dynamic development of GNSS techniques, that could be seen in the last decade, the team carried out further experiments aimed at developing an effective measurement method. Using the acquired experience in this period, another measurement campaign was carried out on the tram tracks in Gdansk. The main goal of these measurements was to check how the new assumptions regarding the method of mounting the antennas as well as their placement on the measuring platform will work in various field conditions. For this purpose, ten sets of GNSS receivers offered by two independent manufacturers – currently market leaders – were used. The choice of testing track section made it possible to analyze the repeatability of results obtained from multiple measurements in conditions of varying GNSS signal availability. The article presents in a synthetic way the course of this research and the obtained results. Keywords: Tram track; Satellite measurements; Accuracy analysis

A general method for the determination of the instantaneous screw axes of one-degree-of-freedom spatial mechanisms

Abstract. This contribution shows that a method proposed previously, for the determination of the instantaneous centers of rotation of planar closed chains, can be generalized for the determination of the instantaneous screw axes of general one-degree-of-freedom spatial mechanisms. Hence, the approach presented in this paper can be applied to any of the closed chains that belong to any of the subgroups of the Euclidean group, SE(3), namely planar, spherical or chains associated with the Schönflies subgroups, among others. Furthermore it can be also applied to multi-loop mechanisms and even to closed chains that are exceptional o paradoxical, as indicated by Hervé.

In This Issue

In This Issue

Localization elements and zip codes in the intracellular transport and localization of messenger RNAs in Saccharomyces cerevisiae.

Intracellular trafficking and localization of mRNAs provide a mechanism of regulation of expression of genes with excellent spatial control. mRNA localization followed by localized translation appears to be a mechanism of targeted protein sorting to a specific cell-compartment, which is linked to the establishment of cell polarity, cell asymmetry, embryonic axis determination, and neuronal plasticity in metazoans. However, the complexity of the mechanism and the components of mRNA localization in higher organisms prompted the use of the unicellular organism Saccharomyces cerevisiae as a simplified model organism to study this vital process. Current knowledge indicates that a variety of mRNAs are asymmetrically and selectively localized to the tip of the bud of the daughter cells, to the vicinity of endoplasmic reticulum, mitochondria, and nucleus in this organism, which are connected to diverse cellular processes. Interestingly, specific cis-acting RNA localization elements (LEs) or RNA zip codes play a crucial role in the localization and trafficking of these localized mRNAs by providing critical binding sites for the specific RNA-binding proteins (RBPs). In this review, we present a comprehensive account of mRNA localization in S. cerevisiae, various types of localization elements influencing the mRNA localization, and the RBPs, which bind to these LEs to implement a number of vital physiological processes. Finally, we emphasize the significance of this process by highlighting their connection to several neuropathological disorders and cancers. This article is categorized under: RNA Export and Localization > RNA Localization.

Regional tourism axes identification using GIS and TOPSIS model (Case study: Hormozgan Province, Iran)

Purpose This paper aims to identify and determine regional tourism axes in Hormozgan Province, Iran, as a region with significant potential Design/methodology/approach The research method is quantitative and uses the fuzzy accreditation tool and TOPSIS model; the identification, determination and ranking of regional tourism axes have been performed by analyzing the spatial distribution of tourism attractions in the GIS environment. Findings The results show that given the capacities of Hormozgan Province, at least 15 axes are recognizable. This paper highlights regional tourism planning as a tool for urban and rural socio-economic development in potential provinces such Hormozgan. Originality/value This study provides a number of practical implications for regional tourism development as follows: it identifies some of the most important potential axes in Hormozgan Province, which can be considered as investment areas in the national and regional tourism development strategy. The spatial results of this study could be embedded in all urban and rural developmental plans in the province. Tourism investment should shift its spatial concentration from the spot approach, especially islands and cities, to the axis approach while equipping those axes as comprehensive spatial strategic regional tourism plans. Sectoral tourism in each sector including sports, economy and nature could be planned as if sectoral institutions and organizations are going to develop their own tourism goals.

Fiber motion-insensitive fiber-based polarization-sensitive optical coherence tomography for optic axis determination

Polarization-sensitive optical coherence tomography (PS-OCT) is widely used to image fibrous biological tissues, providing additional image contrast compared to intensity-based OCT, including birefringence and optic axis orientation information. Here a theoretical and experimental analysis of the effect of the system fiber on determination of sample optic axis orientation using a previously reported algorithm based on the angle between Stokes vectors on the Poincaré sphere in fiber-based PS-OCT experimentally confirms that the algorithm only works correctly when the parameters of the system fiber are kept constant during the imaging acquisition of each frame. To extend the use of the algorithm to situations in which the parameters of the system fiber are varied among A-scans or image frames, which is true when the OCT probe scanning does move the sample arm fiber, we propose the use of polarization maintaining fiber (PMF) with a special polarization axis orientation as the sample arm fiber for extracting sample optic axis orientation using fiber-based PS-OCT systems. The use of the PMF makes the system insensitive to variations of the sample fiber birefringence for determining optic axis orientation by automatically removing the offset ambiguity from each A-scan. We demonstrated by using a computer evaluation model that the proposed method is capable of extracting the relative optic axis orientation correctly when the PMF birefringence is varied among A-scans due to external disturbances to the system fiber, provided that the polarization axis orientation (slow or fast) of the PMF is kept constant during the measurement.

Determination of dielectric axes and transition moment directions in β-Ga2O3 from the polarization dependence of vibrational spectra

β-Ga2O3 is a promising ultrawide bandgap semiconductor for high power and extreme environment applications. The dominant O—H center in Ga2O3 has been assigned to a Ga(1) vacancy–2H (VGa(1)-2H) complex. An analysis of the polarization dependence of the vibrational absorption of the VGa(1)-2D center in monoclinic β-Ga2O3 provides a unique strategy for the determination of both the orientation of the principal dielectric axes in the near infrared and the direction of the vibrational transition moment of the defect.

Analytical model for magnetic‐geared double‐rotor machines and its d–q ‐axis determination

This study presents an analytical sub-domain model for the prediction of various electromagnetic parameters of magnetic-geared double-rotor machine (MGDRM). By dividing the MGDRM into six sub-domains and solving the Maxwell equations in polar coordinates for each region, the vector magnetic potential distribution can be derived. Subsequently, the flux density distribution, back electromotive force, and output torque, can be calculated. Furthermore, based on the proposed model, the equivalent d - q -axis is elaborated. Also, the corresponding d and q inductance can be obtained. It proves that the MGDRM can be regarded as a non-salient-pole synchronous machine. Besides, the power factor of the MGDRM under i d = 0 control is deduced and optimised for the different thicknesses of modulators. In addition, the demagnetisation capability is analysed by adopting the sub-domain model. Finally, the accuracy of proposed sub-domain model for MGDRMs is validated via the finite-element method (FEM).

Расчет сталежелезобетонной балки при мгновенном загружении с учетом нелинейности диаграммы ε-σ бетона

Issues of calculating steel-reinforced concrete beams are considered taking into account a nonlinear concrete diagram based on the Sargin formula. The nonlinear system of equations for determination of curvature and neutral axis, which is solved numerically, is written in explicit form. Explicit expressions for determination of other calculated quantities needed for design of steel-reinforced concrete beams are derived. Numerical examples are given. The analysis of accounting nonlinearity in comparison with the linear calculation is carried out.

Accurate determination of the translational correlation function of two-dimensional solids.

The identification of the different phases of a two-dimensional (2D) system, which might be solid, hexatic, or liquid, requires the accurate determination of the correlation function of the translational and bond-orientational order parameters. According to the Kosterlitz-Thouless-Halperin-Nelson-Young (KTHNY) theory, in the solid phase the translational correlation function decays algebraically, as a consequence of the Mermin-Wagner long-wavelength fluctuations. However, recent results have shown an exponential-like decay. By revisiting different definitions of the translational correlation function commonly used in the literature, here we clarify that the observed exponential-like decay in the solid phase results from an inaccurate determination of the symmetry axis of the solid; the expected power-law behavior is recovered when the symmetry axis is properly identified. We show that, contrary to the common assumption, the symmetry axis of a 2D solid is not fixed by the direction of its global bond-orientational parameter, and we introduce an approach allowing one to determine the symmetry axis from a real space analysis of the sample.

Molecular patterning during the development of Phoronopsis harmeri reveals similarities to rhynchonelliform brachiopods

BackgroundPhoronids, rhynchonelliform and linguliform brachiopods show striking similarities in their embryonic fate maps, in particular in their axis specification and regionalization. However, although brachiopod development has been studied in detail and demonstrated embryonic patterning as a causal factor of the gastrulation mode (protostomy vs deuterostomy), molecular descriptions are still missing in phoronids. To understand whether phoronids display underlying embryonic molecular mechanisms similar to those of brachiopods, here we report the expression patterns of anterior (otx, gsc, six3/6, nk2.1), posterior (cdx, bra) and endomesodermal (foxA, gata4/5/6, twist) markers during the development of the protostomic phoronid Phoronopsis harmeri.ResultsThe transcription factors foxA, gata4/5/6 and cdx show conserved expression in patterning the development and regionalization of the phoronid embryonic gut, with foxA expressed in the presumptive foregut, gata4/5/6 demarcating the midgut and cdx confined to the hindgut. Furthermore, six3/6, usually a well-conserved anterior marker, shows a remarkably dynamic expression, demarcating not only the apical organ and the oral ectoderm, but also clusters of cells of the developing midgut and the anterior mesoderm, similar to what has been reported for brachiopods, bryozoans and some deuterostome Bilateria. Surprisingly, brachyury, a transcription factor often associated with gastrulation movements and mouth and hindgut development, seems not to be involved with these patterning events in phoronids.ConclusionsOur description and comparison of gene expression patterns with other studied Bilateria reveals that the timing of axis determination and cell fate distribution of the phoronid shows highest similarity to that of rhynchonelliform brachiopods, which is likely related to their shared protostomic mode of development. Despite these similarities, the phoronid Ph. harmeri also shows particularities in its development, which hint to divergences in the arrangement of gene regulatory networks responsible for germ layer formation and axis specification.

Effects of three zinc-containing sunscreens on development of purple sea urchin (Strongylocentrotus purpuratus) embryos

The growing popularity of physical sunscreens will lead to an increased release of ingredients from zinc oxide (ZnO) sunscreens into marine environments. Though zinc (Zn) is a necessary micronutrient in the ocean, greater than natural Zn concentrations may be released into marine environments by use of sunscreens. The extent of the consequences of this addition of Zn to the ocean are not fully understood. We investigated the effects of materials released by ZnO- sunscreens on the development of California purple sea urchin, Strongylocentrotus purpuratus. Embryos incubated in various concentrations of Zn (0.01, 0.05, 0.1, 0.5, and 1 mg/L), the sources of which included zinc-containing compounds: ZnO and zinc sulfate (ZnSO4); and ZnO sunscreens: All Good, Badger, and Raw Elements brands. Based on EC50 values, ZnO-containing sunscreens were slightly, but not significantly, more toxic than ZnO and ZnSO4, suggesting that sunscreens may release additional unknown materials that are detrimental to sea urchin embryo development. All concentrations of Zn-exposure resulted in significant malformations (skeletal abnormality, stage arrest, axis determination disruption), which were identified using light and fluorescence confocal microscopy. The concentration of Zn2+ internalized by the developing embryos correlated positively with the concentration of Zn in seawater. Additionally, exposure to both ZnO sunscreens and ZnO and ZnSO4 at 1 mg/L Zn, significantly increased calcein-AM (CAM) accumulation, indicating decreased multidrug resistant (MDR) transporter activity. This is one of the first studies documenting ZnO-containing sunscreens release high concentrations of Zn that are internalized by and have detrimental effects on aquatic organisms.

Fertilization and Cleavage Axes Differ In Primates Conceived By Conventional (IVF) Versus Intracytoplasmic Sperm Injection (ICSI)

With nearly ten million babies conceived globally, using assisted reproductive technologies, fundamental questions remain; e.g., How do the sperm and egg DNA unite? Does ICSI have consequences that IVF does not? Here, pronuclear and mitotic events in nonhuman primate zygotes leading to the establishment of polarity are investigated by multidimensional time-lapse video microscopy and immunocytochemistry. Multiplane videos after ICSI show atypical sperm head displacement beneath the oocyte cortex and eccentric para-tangential pronuclear alignment compared to IVF zygotes. Neither fertilization procedure generates incorporation cones. At first interphase, apposed pronuclei align obliquely to the animal-vegetal axis after ICSI, with asymmetric furrows assembling from the male pronucleus. Furrows form within 30° of the animal pole, but typically, not through the ICSI injection site. Membrane flow drives polar bodies and the ICSI site into the furrow. Mitotic spindle imaging suggests para-tangential pronuclear orientation, which initiates random spindle axes and minimal spindle:cortex interactions. Parthenogenetic pronuclei drift centripetally and assemble astral spindles lacking cortical interactions, leading to random furrows through the animal pole. Conversely, androgenotes display cortex-only pronuclear interactions mimicking ICSI. First cleavage axis determination in primates involves dynamic cortex-microtubule interactions among male pronuclei, centrosomal microtubules, and the animal pole, but not the ICSI site.

Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms.

Unrelated genes establish head-to-tail polarity in embryos of different fly species, raising the question of how they evolve this function. We show that in moth flies (Clogmia, Lutzomyia), a maternal transcript isoform of odd-paired (Zic) is localized in the anterior egg and adopted the role of anterior determinant without essential protein change. Additionally, Clogmia lost maternal germ plasm, which contributes to embryo polarity in fruit flies (Drosophila). In culicine (Culex, Aedes) and anopheline mosquitoes (Anopheles), embryo polarity rests on a previously unnamed zinc finger gene (cucoid), or pangolin (dTcf), respectively. These genes also localize an alternative transcript isoform at the anterior egg pole. Basal-branching crane flies (Nephrotoma) also enrich maternal pangolin transcript at the anterior egg pole, suggesting that pangolin functioned as ancestral axis determinant in flies. In conclusion, flies evolved an unexpected diversity of anterior determinants, and alternative transcript isoforms with distinct expression can adopt fundamentally distinct developmental roles.