Determining Factor Research Articles

Experiences of Social Burden amongst Survivors of Breast Cancer in Gaza: A qualitative study

PurposeThis qualitative study explores how social-cultural factors can either amplify or attenuate prospects for social support following a breast cancer diagnosis. The aim is to analyse narratives of individuals diagnosed with breast cancer to examine how the illness influences social support and hence their post-illness experiences. MethodsForty semi-structured interviews, including thirty-eight with breast cancer survivors, are analysed using a grounded theory approach. Data were collected between September 2020 and April 2021. ResultsParticipants' perceptions indicate that three main factors influenced experiences and the level of social support received. The first involves stigmatised cancer-related discourses and practices affecting women's social interactions and roles. The second is specific to (ex)married participants. It reveals how the foundation of marriage prior to the illness is a determining and influencing factor in the experience of women after illness. The third demonstrates how specific social identities enable coping, negotiation, and challenging cancer-related stigma, turning their experiences toward positivity. ConclusionsThe study concludes that breast cancer acts as a figurative magnifying glass, illuminating latent social practices in the community. This highlights the need to nurture existing social bonds or address the fragility of ties within distinct social categories. Implications for Cancer SurvivorsThe research suggests implementing customised support interventions aligned with each group of survivors' unique needs. Furthermore, enhancing awareness within patients' social networks regarding the illness and how to provide support, along with enhancing survivors' financial security through economic empowerment, may contribute to more effective coping with the social consequences of the illness.

A phase separation prediction model for CO2 capture by biphasic amine absorbents

The biphasic amine absorbent upon absorbing CO2, separates into CO2 poor and CO2 rich phases, making it a third-generation chemical absorbent with energy-saving potential. However, the current method of constructing biphasic amine absorbents involves screening phase separation agents through a large number of experiments, which involves significant amount of trial and error. In this study, a phase separation prediction model was built for CO2 capture by biphasic amine absorbents for quick screening of phase separation agents. The phase separation of CO2 absorption by organic amine 2-amino-2-methyl-1-propanol (AMP) using 34 phase separation agents was statistically analyzed based on 14 molecular descriptors of the solvents. The factors influencing the phase separation were thoroughly explored. It is proposed that the relative dielectric constant or molecular polarity index can replace the traditional polarity evaluation index, dipole moment, to better describe the phase separation situation. Additionally, it is found that the ability of phase separation agents to form hydrogen bonds, particularly as a hydrogen bond donor is the determining factor for phase separation to occur. Ultimately, the preferred molecular descriptors are used as predictors, leading to the development of a prediction model for phase separation that achieves high-accuracy predictions solely through theoretical calculation parameters. The model considerably reducing the construction costs of biphasic amine absorbents.

Changes in haptoglobin genotype-based gene expressions upon the observance of dawn-to-dusk intermittent fasting: a prospective cohort study on overweight and obese individuals.

Intermittent fasting (IF) has been reported to be involved in ameliorating oxidative stress and lessening the systemic-low grade inflammation that predisposes to chronic diseases. Gene polymorphism is currently a main determining factor for the metabolic responses to different dietary and lifestyle modifications. The current study was designed to explore the effect of observing four-week, dawn to dusk IF by participants with obesity on gene expression of the anti-inflammatory CD163, oxidative stress, and bioenergetics enzymes (SOD2, Nrf2, and TFAM), as well as metabolic and cellular regulatory genes (SIRT1 and SIRT3). Further, the study aimed to find out how haptoglobin (Hp) polymorphism modulates gene expression of the aforementioned genes and to determine changes in relative gene expressions of the aforementioned six genes based on Hp polymorphism in response to IF. Haptoglobin genotype was determined for the study subjects, and gene expressions were determined using qPCR. Gene expressions were assessed before and at the end of four consecutive weeks, dawn to sunset IF. The expressions of CD163, SOD, NfF2, and TFAM genes have significantly increased at the end of IF. At the same time, SIRT3 significantly decreased, implying that observing four consecutive weeks of dawn-to-dusk IF may enhance antioxidative stress response and reduce systemic inflammation. Participants with genotypes Hp2-1 and Hp2-2 revealed upregulation of the antioxidant genes in response to the metabolic stress induced by IF compared with Hp1-1, implying that Hp polymorphism plays a key role in shaping the body's response to dietary modifications such as fasting.

Maternal death before admission to the Sylvanus Olympia University Hospital Center (CHU SO) epidemiological and etiological aspects

Objective: determine the epidemiological and etiological profiles of a pregnant, parturient or women given birth before or within 10 minutes of admission Methods: This was a descriptive cross-sectional study from January 1, 2014, to December 31, 2021. All maternal deaths occurring before admission and within 10 minutes of admission to the clinic were included in the study. Of gynecology and obstetrics at CHU SO. The data were processed by Epi info version 7 software. Results: in total, 654 maternal deaths including 153 maternal deaths before admission were recorded, corresponding to 23.4% of all maternal deaths. The median age was 30.2 years. 37.2% of women were uneducated. 41.2% were resellers. 79.1% of women were cohabiting. 47.1% of women had performed less than 3 ANC. 43.8% of the women who died had completed their ANC in a medical center. 54.3% by a midwife, 37.3% by unqualified personnel. 62.7% of deaths occurred postpartum and 36.3% during pregnancy. 79.1% were referrals. 88.9% of the women who died arrived in a non-medical taxi car. Among the 57 patients who died during their pregnancy, 40.3% were carrying a pregnancy of 28 to 36 weeks, and 36.3% were full-term pregnancies. Among the 96 women who died postpartum; 93.3% had given birth vaginally. Among the 121 referrals, 34.7% came from a birthing center, 56.2% were referred by a state midwife and 30.6% by unqualified personnel; 46.3% referred without a reference form, 94.3% were referred without a venous access. In 10.7% the reason for evacuation was bleeding from the delivery with an average evacuation time of one-hour 5minutes. 60.3% of women who died had an evacuation delay of more than one hour. 94.8% of patients died of direct obstetric causes including immediate postpartum hemorrhage in 60.1% of cases. Conclusion: deaths before admission constitute an increasingly growing problem at CHU SO. Late referral is a determining factor in maternal deaths before admission.

Pengaruh Media Arcademics terhadap Minat Belajar Matematika Peserta Didik di SD Miftahussadah

The use of learning media that is easy to make and use is needed by teachers along with technological advances. Learning media has a significant influence on the learning process. Observations at Miftahussadah Elementary School in Gebog Subdistrict show that although learning is quite varied, conventional methods without the help of media are still often used. Students' learning motivation is a determining factor in learning activities. The more interesting the learning media used, the higher the tendency and attention of students in learning. This study aims to see the effect of Arcademics media on students' interest in learning. This study used a one group pretest-posttest pre-experiment design. The sampling technique was purposive sampling with a total of 14 students from class V SD Miftahussadah. Data analysis includes validity and reliability tests, normality tests, homogeneity tests (Levene's test), and t-tests with the help of SPSS applications. The results showed that the use of Arcademics media had a positive influence on students' learning motivation.

Influence of a local diabatic heating source on the midlatitude circulation

AbstractDiabatic heating due to latent heat release in the storm tracks plays an important but poorly understood role in the midlatitude circulation. To examine how localised diabatic heating affects the circulation, a dry model is used to apply midtropospheric perturbations to the radiative‐equilibrium temperature profile to which the model is relaxed. This allows us to isolate the one‐way causal influence of diabatic heating on the circulation without feedbacks of the circulation onto the heating. By applying switch‐on perturbations at various latitudes, the mechanisms by which an equilibrated state is reached are examined. In all cases, the equilibrated circulation exhibits a dynamically insensitive jet structure with eddies maintaining a region of self‐concentrated baroclinicity, latitudinally shifted away from the heating perturbation. However, the initial response is generally very different. For heating poleward of the jet, there is an initial thermal‐wind adjustment and weakened eddy heat fluxes, followed later by weakened eddy momentum fluxes that maintain an equilibrated equatorward jet shift. For heating equatorward of the jet, the evolution is more complex with an initial strengthening of the eddy heat fluxes that dominantly balance the imposed heating, as well as a weakening of the Hadley cell. Further, the initial thermal‐wind adjustment immediately modifies the subtropical critical lines and eddy momentum fluxes that encourage an 15° poleward propagation from the Subtropics to Midlatitudes, yielding an equilibrated poleward jet shift. The overall determining factor in balancing the imposed heating at equilibration is the local climatological heat budget: if the climatological eddy heat fluxes locally warm, such as in mid‐to‐high latitudes, then this effect weakens, whereas if the climatological overturning circulation locally warms, such as in the Subtropics, then this effect weakens. The insensitivity of the equilibrated jet profile to the imposed heating is remarkable given the maintenance mechanisms vary drastically according to heating latitude.

ЖАПОНИЯДАҒЫ САЛЫҚТЫҚ ӘКІМШІЛЕНДІРУДІ ЦИФРЛАНДЫРУ ТӘЖІРИБЕСІН ЗЕРТТЕУ

The tax policy of the state in conjunction with the methods of tax administration is a determining factor influencing the amount of tax revenues of the budget. Tax discipline, forms and close interaction between taxpayers and regulatory authorities also play a significant role. The development of information and communication technologies (ICT) in recent decades has provided the tax authorities with a wide range of opportunities to increase government revenue, improve the efficiency and quality of services provided to taxpayers, including electronic filing of returns and payment of taxes, while reducing the administrative burden on taxpayers and reducing public administration costs. The first phase of digitalization was the computerization of routine tax administration processes (such as taxpayer registration and income records), and in the second half of last decade and early this decade, many tax authorities adapted their websites to simplify operations by introducing online forms and calculators for taxpayers. In June 2017, Japan National Tax Agency published a strategic plan for the Japanese tax administration called "Looking to the Future." This includes the pursuit of sound taxation and good governance to ensure that taxes are paid based on the understanding and trust of taxpayers. The National Tax Agency of Japan is well aware of the importance of continually moving toward the future it seeks, emphasizing the goal of transparent tax administration. Keywords: tax and customs administration, OECD countries, tax and customs, administrative costs, Tax Code, tax authorities, taxpayers, tax relations, digitalization.

The Determinant Factor of Employee Engagement at Palm Oil Plantations Company in Central Kalimantan Province

With today's tougher business competition, many companies have realized how important human resources (HR) are. Organizational culture, knowledge management, and employee engagement are the keys to the success of human resources. This study aims to see the influence of organizational culture, knowledge management on employee engagement. This type of research uses mixed methods. Mixed Methods is a research method that combines quantitative research and qualitative research. In this research method using a sequential explanatory combination, starting with using quantitative methods and then expanding with qualitative and comparing the average results of both. In this study using a linearity test which is used to identify the regression model of the independent variable on the dependent variable, the study focused on a population of 1960 companies and 321 employees from the Palm Oil Company Group. The sample size consisted of 179 employees. The findings of the study are: 1) Organizational culture positively impacts employee engagement in Palm Oil Companies in Central Kalimantan Province, and 2) Knowledge management also has a positive effect on employee engagement in Palm Oil Companies in Central Kalimantan Province.

Three-Dimensional Evaluation of Impacted Mandibular Third Molar Angulation and its Impact on Lingual Cortical Bone Thickness: A Retrospective Cone-Beam Computed Tomography Study

Background: The removal of impacted lower third molars surgically can cause complications, and the lingual cortical bone thickness in this region becomes a determining factor in the risk of perforation and injury to the lingual nerve (LN). This study was conducted to assess the relationship between different angulations of impacted lower third molars based on Winter’s classification and the thickness of the lingual cortical bone. Variations in lingual cortical bone thickness among the genders were evaluated as well. Methods: Cone-beam computed tomography (CBCT) scans of 50 impacted lower third molar teeth of 50 patients (26 men and 24 women) were evaluated in this study. The lingual bone thickness surrounding impacted lower mandibular teeth was measured at three key points, namely, the cemento-enamel junction of the second mandibular molar, the mid-root of the impacted third molar, and the root apex of the impacted third molar. Mesiodistal angulation and buccolingual angulations of the impacted mandibular third molars underwent investigation. Statistical analysis was conducted using SPSS 23. Data were analyzed using the independent sample t test, one-way ANOVA, multiple linear regression analysis, and Fisher’s exact test. Results: There was a statistically significant relationship between the means of lingual cortical bone thickness surrounding the third molars based on Winter’s classification of third molars impacted at mesiodistal angulation (P=0.00). Regarding gender, buccolingual angulation demonstrated a statistically significant relationship among the means of lingual bone thickness around the third molars (P=0.022). Conclusion: In our study, the thickness of the lingual cortical bone was notably affected in the middle and apical areas of the impacted third molar region. The variable position of the LN near the mandible third molar region was significant in dental procedures due to its proximity. Three-dimensional (3D) imaging CBCT provides preoperative risk assessment that reduces preventable complications that cannot be answered by 2D imaging.

Mechanism of pyrite depression by marine Fe(II)-oxidizing bacteria in seawater flotation

Seawater flotation is a promising technique to reduce environmental and economic loads in mineral processing. This study attempted to depress pyrite, a common gangue sulfide mineral, using two marine iron (Fe) oxidizing bacteria (MFeOB), Thalassospira sp. TF-1 and Mariprofundus sp. E-4, in seawater flotation without pH control; the MFeOB could contribute to hydrophilization of the pyrite surface by oxidation and/or adhesion of bacterial cells. Pyrite or chalcopyrite samples were preconditioned in seawater containing MFeOB for different times (15 min or 30 min). As a result of flotation experiments, the recovery of pyrite preconditioned without MFeOB (i.e., control sample) decreased to 64.2 % after 30 min reaction. The same recovery was observed when pyrite was preconditioned with Thalassospira sp. TF-1, whereas the recovery was successfully decreased to 20.2 % after preconditioning with Mariprofundus sp. E-4 for 30 min. X-ray photoelectron spectroscopy analysis of preconditioned pyrite samples showed no significant difference of Fe-oxidizing compounds between with and without MFeOB reaction, suggesting that the formation of hydrophilic substances such as Fe(OH)3 derived from pyrite oxidation by MFeOB is unlikely to be the main reason for the pyrite depression by Mariprofundus sp. E-4. The adhesion experiment revealed that MFeOB cells could cover the pyrite surface but not the chalcopyrite surface, showing that the hydrophilicity of Mariprofundus sp. E-4 cell caused the pyrite depression. This result suggests that the hydrophilic/hydrophobic properties of bacterial cells are a significant determining factor in pyrite recovery in seawater flotation in the case of MFeOB.

A new hybrid approach to the impact of renewable energy consumption on economic growth: sectoral differences in European Union countries

The current energy crisis has shown all states that energy from renewable sources can be a determining factor in the states’ sustainable development. Several papers have studied the relationship between renewable energy consumption and economic development, finding various situations, but there is no consensus. Thus, this study aims to first investigate the causal relationship between economic growth and total and sectoral renewable energy consumption (European Union and each Member State, for 2004–2020) by testing various linear and non-linear regressions to choose the fit model. Second, the investigation extends to analysing the impact of renewable energy consumption by sector on economic development. A hybrid approach is used, namely structural equation modelling and artificial neural networks. The study findings indicate the effect and the meaning (directly or inversely) exerted by the three sectoral components on economic growth, with different intensities from one country to another. There is a significant influence on the consumption of renewable energy in the heating and cooling sectors and transport on gross domestic product at the European Union level and for most member states. Based on the obtained results, a series of theoretical, practical, and political implications are provided.

Enhancing environmental sustainability in Asian textile supply chains: insights from agile practices and mediating variables

The current energy crisis has shown all states that energy from renewable sources can be a determining factor in the states’ sustainable development. Several papers have studied the relationship between renewable energy consumption and economic development, finding various situations, but there is no consensus. Thus, this study aims to first investigate the causal relationship between economic growth and total and sectoral renewable energy consumption (European Union and each Member State, for 2004–2020) by testing various linear and non-linear regressions to choose the fit model. Second, the investigation extends to analysing the impact of renewable energy consumption by sector on economic development. A hybrid approach is used, namely structural equation modelling and artificial neural networks. The study findings indicate the effect and the meaning (directly or inversely) exerted by the three sectoral components on economic growth, with different intensities from one country to another. There is a significant influence on the consumption of renewable energy in the heating and cooling sectors and transport on gross domestic product at the European Union level and for most member states. Based on the obtained results, a series of theoretical, practical, and political implications are provided.

Assessing the Relationships between Physical Activity, a Healthy Life, and Personal Happiness in European Union Countries.

Background: Maintaining a physically active lifestyle is a determinant factor of a healthy life and personal happiness. Meanwhile, physical inactivity remains a significant issue, resulting in negative consequences for public health. Objectives: This paper investigates the relationships between physical activity, physical inactivity, a healthy life, life expectancy, and personal happiness in European Union (EU) countries. Methods: This empirical study uses an artificial neural network and cluster analysis to analyze and interpret data from 27 EU countries. Artificial neural network analysis enables the assessment of the relationships between physical activity and inactivity, a healthy life, and personal happiness, while cluster analysis identifies groups of EU countries based on physical activity, healthy life, and personal happiness indicators. Results: The results show significant positive links between physical activity and improvements in healthy living and personal happiness. Conclusions: This study highlights considerable variations among EU countries regarding the levels of physical activity, healthy living, and personal happiness, emphasizing the importance of promoting physical activity to enhance public health and overall well-being. The findings suggest the need to develop customized policies that address country-specific factors and promote an active lifestyle.

Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis.

The endothelial barrier plays an active role in transendothelial tumor cell migration during metastasis, however, the endothelial regulatory elements of this step remain obscure. Here we show that endothelial RhoA activation is a determining factor during this process. Breast tumor cell-induced endothelial RhoA activation is the combined outcome of paracrine IL-8-dependent and cell-to-cell contact β 1 integrin-mediated mechanisms, with elements of this pathway correlating with clinical data. Endothelial-specific RhoA blockade or in vivo deficiency inhibited the transendothelial migration and metastatic potential of human breast tumor and three murine syngeneic tumor cell lines, similar to the pharmacological blockade of the downstream RhoA pathway. These findings highlight endothelial RhoA as a potent, universal target in the tumor microenvironment for anti-metastatic treatment of solid tumors.

The effect of essential skills on perceived employability: a case of Malaysian undergraduates in energy-focused universities

PurposeThe purpose of this study is to examine the effect of technical skills, soft skills and social mobility skills on the perceived employability of Malaysian undergraduates in energy-focused universities. This study also aims to investigate the moderating effects of academic performance on such relationships.Design/methodology/approachTo accomplish these objectives, this study employed partial least squares-structural equation modelling (PLS-SEM) to analyse data obtained from 247 Malaysian undergraduates from public and private energy-focused universities across Malaysia. The Human Capital Theory served as the overarching theoretical framework for the study.FindingsThe study reveals that even if an undergraduate has stellar grades, they will not help him/her to land a job if they lack basic technical and computing skills. This study also indicates that undergraduates’ current academic performance affects their perceived employability despite already possessing the necessary soft skills. Along with academic performance, social mobility skills can be a determining factor in how graduates see their own employability. This is because social mobility has a significant impact on graduates’ chances of finding gainful employment.Research limitations/implicationsThis study provides insights into how technical skills, soft skills and social mobility skills influence the perceived employability of Malaysian undergraduates, especially in energy-focused universities, and the role of various parties involved. These parties, such as higher education institutions, are the key players that can initiate strategies to enhance specific skills and steer a public conversation towards a more methodical strategy for boosting graduates’ employability for future employment. This research also sheds light on how to better prepare for emerging job opportunities in the energy sector.Originality/valueThe study examines the effect of technical skills, soft skills and social mobility skills on the perceived employability of Malaysian undergraduates in energy-focused universities for future employment among Malaysia’s universities’ graduates. By providing a multidisciplinary viewpoint, this study paves the way for future research partnerships among experts in higher education, researchers in related fields and career researchers.

Emerging Technologies for Decarbonizing Silicon Production

AbstractSilicon (Si) is an important material for alloying, solar photovoltaics, and electronics. However, current methods of producing silicon require energy consumption of around 11–13 kWh/kgSi and direct carbon emissions are 4.7–5 tons CO2 per ton Si which conflicts with global efforts to limit climate change. In this work, we discuss several promising methods for reducing or eliminating carbon emissions from the silicon production process. Such methods include using biocarbon, integrating the current process with carbon capture and utilization/storage (CCU/CCS), metallothermic reduction, hydrogen reduction, and molten salt electrolysis. We present the positive aspects and challenges of each approach. Biocarbon coupled with CCU/CCS is the most industrially mature technology and can be carbon–neutral or -negative but is not carbon-free. Hydrogen directly reducing silicon dioxide is not thermodynamically favorable, but it may be viable to use hydrogen in conjunction with other processes to reduce emissions. Metallothermic and electrochemical methods of production are promising and have the potential to create high-purity silicon with no reduction-related carbon emissions but have only been demonstrated at lab scale. Economic viability will likely be the next determining factor for which technologies are more widely researched and implemented. Graphical Abstract

Shear Force of Interior Beam–Column Joints under Symmetrical Loading with Two Transverse Forces on the Beam †

The beam-to-column connection is a particularly vulnerable element in frame structures under seismic action and is often responsible for building damages. Experimental investigations carried out over the past six decades on shear strength in frame joints have not led to the establishment of a uniform procedure in the design codes of different countries. The reason lies probably in the varied nature of the investigated parameters and in the varied configurations of beam–column connections. A good knowledge of the forces passing through the frame joints in the beam–beam and column–column direction would allow both their adequate computation in new buildings and the verification of existing ones without requiring experimental studies. In the design codes of the leading countries in seismic engineering, the shear force is determined by the capacitive method, considering only the area of the longitudinal reinforcement of the beam passing through the column. This method shows us how much shear force the beam reinforcement can take, but not what the magnitude of the resulting forces actually is as a result of the acting loads. In addition, the method of the codes does not indicate the contribution of the concrete to the total magnitude of the shear force in the beam–column connection. In the proposed mathematical model for calculating the forces that leave the beam, the full dimensions of the cross-section of the beam were taken into account. The material properties and cross-sectional shape were also taken into account. A determining factor for the magnitude of forces entering the beam–column joint is the acting load on the beam. In this paper, the load of two transverse forces was considered. The forces are applied in different possible positions, while remaining symmetrically located on the beam. The calculations are based on Menabrea’s theorem to determine the hyperstatic unknowns. The results of the proposed method for the considered beam show that the magnitude of the shear force differs from that accepted in the literature and the norms by 2% to 27%, depending on the stage of development of the crack. In comparison, the Eurocode-recommended method shows differences in the order of 27% to 40% for the adopted beam under static loads.

Abstract A134: Overcoming barriers to prostate cancer screening: A tethered educational video and mobile screening program

Abstract Background: Prostate cancer (PC) is the most commonly diagnosed cancer in men. One in 8 White and 1 in 6 Black men will be diagnosed with PC in their lifetime. The current prostate cancer screening (PCS) guidelines recommend shared decision making to discuss the advantages and disadvantages of PCS. In Philadelphia, among men over 40 years of age, only 39% and 18% have discussed the advantages and disadvantages of PCS with a provider, respectively. Among men over 50 years of age, only 47% have had a Prostate Specific Antigen (PSA) test. This research evaluated an educational video designed to increase awareness of the advantages and disadvantages of PCS and provided access to mobile PSA screening among the diverse men in Philadelphia. Methods: Between April-May 2024, we enrolled men aged 40+ at community events within and around the city of Philadelphia and excluded men who previously participated in the study. Screening events were advertised through social media, printed flyers, emails, and text messages disseminated by labor union administrators to union members. Participants completed a questionnaire which examined PC and PCS knowledge, decisional conflict, and likelihood to screen before and after viewing a 12-minute educational video on an iPad or personal device. The video consisted of a conversation between a local pastor, who is a Black PC survivor, and a urologist. The video included the pastor’s personal experience with PC and allowed him and the urologist to have the opportunity to address common PC misconceptions and myths. After the video, participants provided video feedback. A $10 gift card and giveaways were offered before presenting the option for on-site PSA draws by a licensed phlebotomist. Results: A total of 133 men (38% Black; 56% White, 10% Hispanic; mean age of 53 years old (s.d.=10.4)) completed the pre and post questionnaires. A total of 61% of participants had never had a PSA test. Twenty-two percent did not know blood testing was an option, and 28% did not know they needed a PSA test. Thirty-two percent of participants would have been somewhat or very unlikely to get screened without this program. Having the screening option come to their community or place of work was the determining factor for 81% of screened participants. After watching the video, PC knowledge improved in 6 of 10 items (overall knowledge score pre vs. post p<.01). Post video, decisional conflict was reduced in 9 of the 10 questionnaire items (each item had a p≤.001). A total of 95% of participants stated ‘yes’, they would undergo PCS after watching the video versus 69% being either somewhat or very likely to get screened before watching the video (p<0.001). All 95% were screened on-site. The video information was deemed useful to 99% and credible by 97% of respondents. Conclusion: This educational video increased PCS awareness, intention to screen for PC, and completion of PCS. When coupled with an educational video, mobile PSA screening initiatives are an effective and efficient way to increase access to PSA screening for diverse men. Citation Format: Mallorie C. Jones, William Buckley, Alexandra Cordoba, Suji Kim, David Barreto, Debanjan Pain, Vivian Nguyen, Blane Newberry, Daniel Lee, Carmen E. Guerra. Overcoming barriers to prostate cancer screening: A tethered educational video and mobile screening program [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A134.

Temperature Interference on ZIKV and CHIKV Cycles in Mosquitoes and Mammalian Cells.

Temperature is a determining factor for the viral cycle. In this study, we investigate the effect of different temperatures on the cycles of two important arboviruses-Zika (ZIKV) and Chikungunya (CHIKV)-in Vero (mammalian) and C6/36 (mosquito) cells. We compare genome quantification to infectivity at 28 °C and 37 °C in both cell types. Virus-cell interaction was also examined by transmission electron microscopy, allowing the observation of phenomena such as virus-surfing and giant forms for CHIKV, as well as the the scarcity of ZIKV in C6/36 cells compared to its cycle in mammalian cells.

Assessment of tropospheric NO2 concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–2023

This study presents a temporal evaluation of the tropospheric NO2 column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO2 levels before, during and after the tournament over Greater Doha. Analysis of annual NO2 levels from 2019 to 2023 showed an increase in 2022 compared to that of the previous three years and a clear decrease in 2023 post the completion of the world cup preparations and hosting. Results also showed an increase in NO2 levels during winter compared to that in summer, with wind speed being an important determining factor. Findings showed that Fridays and Saturdays (both constitute the local weekend in Qatar) were 44% and 13% lower than that of the averaged weekdays, respectively. The annual NO2 levels in the post-world cup year of 2023 were found to be 24% lower than that in 2022 and around 16% lower than that of the previous years. NO2 levels during the World Cup tournament (20 Nov to Dec 18, 2022) were found to be higher than that of the same corresponding periods in all other available years including an increase of 27% compared to that in 2023. Wind speed played an important role in determining the NO2 levels during the world cup period and accounted for >96% of their daily variability, indicating that meteorological factors substantially influenced the NO2 column during the event.