Efficient energy conversion technologies are essential for mitigating the environmental impact of industrial activities. The development and application of high-efficiency heat exchangers are key components in this endeavor. Heat exchangers based on triply periodic minimal surfaces (TPMS) are widely acknowledged for their exceptional thermal-hydraulic performance. However, current research mainly focuses on the design and optimization of heat exchangers with standard TPMS structures. In this study, a hybrid process is utilized to construct ten novel heat exchangers, followed by comprehensive investigations of their internal flow fields using three-dimensional numerical simulations. In order to establish a baseline, five standard TPMS structures are also introduced as reference cases. The results reveal that complex secondary flow distributions and velocity variations are critical factors influencing the thermal-hydraulic performance. Moreover, the influence of different standard TPMS cells on the flow and heat transfer characteristics varies during the hybridization process. Specifically, the inclusion of the Schwarz cell generally leads to an improvement in heat transfer, while the presence of the Lindinoid cell may result in a deterioration of heat transfer. The Diamond and Lindinoid cells have an adverse impact on the flow characteristics, while the Gyroid and Neovius cells enhance the flow characteristics. To evaluate the overall thermal-hydraulic performance of different channels, a comprehensive performance assessment is introduced. The Diamond channel and the Gyroid-Neovius channel show superior overall performance in their respective Reynolds number regions, with the former exhibiting better flow characteristics and the latter has outstanding heat transfer performance.