The Eastern Mediterranean region, a vital conduit for global maritime trade, faces significant environmental challenges due to marine pollution, particularly from oil spills. This is the first study covering the long period of comprehensive monitoring of oil pollution using the full mission of Sentinel-1 Synthetic Aperture Radar (SAR) data in the Mediterranean Sea, so this research aims to detect and analyze comprehensively the occurrence of oil spills in the Eastern Mediterranean over a decade (2014–2023). This study focuses on identifying geographical distribution patterns, proximity to shorelines, frequency across maritime zones, and potential sources of these spills, especially around major ports and maritime routes. This study utilizes SAR data from the Sentinel-1 satellite. The methodology included automated detection algorithms within the Sentinel application platform (SNAP) and integration with GIS mapping to study oil spill patterns and characteristics. Over 1000 Sentinel-1 scenes were investigated in the northern Mediterranean waters off the coast of Egypt, to detect and analyze 355 oil spill events with a total impacted area of more than 6000 km2. The analysis of temporal spill distribution reveals significant fluctuations from year to year. Within the entire timeline of the study, 2017 had the largest spatial areas covering one thousand square kilometers. In contrast, the single largest spill recorded during the study period occurred in 2020, covering 198.73 square kilometers. The results identified a non-uniform distribution of oil spills and primarily exhibiting elongated patterns aligned with the navigation routes. The distinct increase of oil spill incidents was within the Exclusive Economic Zone (EEZ), obviously drifted to the coastline and around major ports. The study emphasizes the critical role of remote sensing technologies in addressing environmental challenges caused by the maritime transport sector, advocating for enhanced monitoring and regulatory enforcement to protect marine ecosystems and support sustainable naval activities. The findings highlight the urgent need for targeted continuous monitoring and rapid response strategies in high-traffic maritime areas, particularly around the EEZ and major ports.