Objective To investigate the old patients with vagina inflammation Candida and Trichomonas infection situation,provide the basis for clinical diagnosis and treatment. Methods 6 738 patients with vagina inflammation in the vaginal were retrospectively analyzed. Candida and Trichomonas detection results were compared, and focused on elderly patients with three different age groups(group 55-65years old,>65-75years old group and the group>75years)of two kinds of pathogenic microorganism infection status. Results 125 cases of detection in elderly patients with vagina inflammation,accounted for 1.8%,including detection Candida 37 cases, infection rate was 29.6%;Trichomonas detection 12 cases,infection rate was 9.6%; The dual infection in 2 cases, infection rate was 1.6%.55-65years old group,>65-75years old group and>5-year-old group infection rates were 52.2%(chisquare=6.33),30.4%(chi-square=6.21),10.0%(chi-square=6.13).55-65years old group of two kinds of pathogenic microorganism infection rates were higher than that of>65-75years old group and>75years old group,>65 -75years old group is higher than that of>75-year-old,differences were statistically significant(P<0.05). Conclusion In elderly patients with vagina inflammation has certain Candida and Trichomonas infection rate, the main pathogen of bacterial infection of Candida, and younger people has higher infection rate than older people. Key words: Candida; Trichomonas vaginalis; Vaginal inflammation; Aged