Six patients with spinal cord injuries, including three paraplegics and two quadriplegics, underwent extracorporeal shock wave lithotripsy (ESWL) successfully for removal of ureteral calculi. The five proximal-ureteral calculi measured 20 to 35 mm; the single distal ureteral calculus measured 10 to 15 mm. General anesthesia was used in four patients, spinal anesthesia in one, and no anesthesia in one. All had pre-ESWL obstruction necessitating placement of a percutaneous nephrostomy tube, which was used during the procedure to instill constrast medium to monitor stone destruction. All patients had stone-free ureters on antegrade nephrostograms 7 days after ESWL. There were no significant complications, although one patient had fever and leukocytosis that resolved with intravenous antibiotics. ESWL appears to be highly successful in the removal of ureteral calculi in patients with spinal cord injuries.